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  3. Novomix 50 100IU/ml Penfill 3ml

Novomix 50 100IU/ml Penfill 3ml, Pack of 1
Novomix 50 100IU/ml Penfill 3ml, Pack of 1
Novomix 50 100IU/ml Penfill 3ml, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Novomix 50 100IU/ml Penfill 3ml is used to treat diabetes mellitus in children (above 2 years of age) and adults. It maintains blood sugar levels in adults and children. It ensures rapid and stable sugar control by facilitating the reuptake of sugar in muscle and fat cells, while also decreasing sugar production in the liver. It may cause side effects such as weight gain, injection site allergic reaction, rash, lipodystrophy (skin thickening or pits at the injection site), hypoglycaemia (low blood glucose level), and itching.

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Composition :

INSULIN ASPART PROTAMINE-50% + INSULIN ASPART-50%

Manufacturer/Marketer :

Novo Nordisk India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Novomix 50 100IU/ml Penfill 3ml

Novomix 50 100IU/ml Penfill 3ml used for the treatment of both type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in adults and children. In Type 1 Diabetes Mellitus, the body does not produce enough insulin to regulate blood sugar levels. In type 2 diabetes mellitus, either the body stops producing enough insulin (a hormone that helps lower blood sugar levels) or there is resistance to the action of insulin. As a result, insulin is produced in large quantities, but it is unable to function properly on the body's organs.

Novomix 50 100IU/ml Penfill 3ml is a combination medicine that works by promoting the recovery of sugar in muscle and fat cells and suppressing sugar production in the liver. Together, Novomix 50 100IU/ml Penfill 3ml confirms rapid and stable sugar control.

Not everyone who is taking Novomix 50 100IU/ml Penfill 3ml will get these side effects. You may experience rash, injection site allergic reaction, weight gain, edema (tissue swelling or fluid overload), skin thickening at the injection site, low blood glucose levels, and itching. Most of these side effects of Novomix 50 100IU/ml Penfill 3ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Novomix 50 100IU/ml Penfill 3ml should be taken 15 minutes before food or as advised by your doctor. It should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks) only. Your doctor will explain how to inject the medicine by your own. However, if it is difficult to inject the medicine, ask a healthcare professional to administer it. Along with Novomix 50 100IU/ml Penfill 3ml, you should take a healthy diet, do regular exercise, and maintain weight as advised by your doctor.

Inform your doctor if you are allergic to Novomix 50 100IU/ml Penfill 3ml. Do not take Novomix 50 100IU/ml Penfill 3ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription or recreational drugs. Try not to stop receiving Novomix 50 100IU/ml Penfill 3ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Novomix 50 100IU/ml Penfill 3ml is a cold chain medicine, and so it must be stored in the refrigerator between 2-8 degrees Celsius, or else its efficiency might get lost. Do not store in the freezer or the fridge.

Uses of Novomix 50 100IU/ml Penfill 3ml

Novomix 50 100IU/ml Penfill 3ml is used in the treatment of Type 1 diabetes mellitus and Type 2 diabetes mellitus. The detailed uses of Novomix 50 100IU/ml Penfill 3ml are as follows:

  • Diabetes Management: Novomix 50 100IU/ml Penfill 3ml is widely prescribed for controlling blood sugar levels in individuals with Type 1 and Type 2 diabetes.
  • Combination Therapy: Novomix 50 100IU/ml Penfill 3ml may be used alongside other oral antidiabetic medications to achieve improved blood sugar control, offering a comprehensive approach to diabetes management.
  • Reduction of Cardiovascular Risks: Regular use of Novomix 50 100IU/ml Penfill 3ml can help reduce the risk of cardiovascular diseases in diabetic patients.

Directions for Use

  • Novomix 50 100IU/ml Penfill 3ml should be administered 15 minutes before taking the meal. 
  • Novomix 50 100IU/ml Penfill 3ml is usually given once or twice daily when both rapid and prolonged insulin effects are desired or as advised by a doctor. 
  • Your doctor will train you on how to use Novomix 50 100IU/ml Penfill 3ml at home. Check the label for directions and use it as advised by the doctor. 
  • Novomix 50 100IU/ml Penfill 3ml should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm. Clean the injection site, pinch the skin, insert the needle, and inject the insulin. 
  • Rotate the injection site every time. Do not inject into skin that is red, bruised, or hard. Do not reuse or share needles.

Medicinal Benefits

  • Novomix 50 100IU/ml Penfill 3ml works by ensuring rapid and stable sugar control. It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver.
  • Novomix 50 100IU/ml Penfill 3ml helps in improving the glycemic control, which in turn decreases the risk of progression of complications of diabetes like damage of the retina, damage to the kidney, damage to nerve cells, delayed wound healing, diabetic foot ulcer and others.
  • Novomix 50 100IU/ml Penfill 3ml offers the flexibility to adjust insulin intake based on carbohydrate consumption and blood glucose levels, ensuring tailored diabetes management. The
  • The Penfill format facilitates precise and convenient dosing using an insulin pen device, thereby enhancing the ease of use for diabetic patients.

How Novomix 50 100IU/ml Penfill 3ml Works

Novomix 50 100IU/ml Penfill 3ml is a combination medicine that contains insulin aspart (rapid-acting) and the other insulin aspart protamine (longer-acting). Insulin aspart has a fast onset of action, and insulin aspart protamine has a prolonged duration of action. Together, they ensure rapid and stable sugar control by enabling the reuptake of sugar in muscle and fat cells and decreasing sugar production in the liver.

Storage

• Store in a cool and dry place away from sunlight.• Keep Novomix 50 100IU/ml Penfill 3ml out of the sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Novomix 50 100IU/ml Penfill 3ml

Do not take more than the prescribed dose of Novomix 50 100IU/ml Penfill 3ml as it may cause an overdose. Insulin overdose may cause life-threatening hypoglycemia (low blood pressure). The symptoms of overdose include blurred vision, drowsiness, trouble speaking, confusion, muscle weakness, jerky or clumsy movements, fits or loss of consciousness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Inform your doctor if you are allergic to Novomix 50 100IU/ml Penfill 3ml. 
  • Do not take Novomix 50 100IU/ml Penfill 3ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription or recreational drugs. 
  • Try not to stop receiving Novomix 50 100IU/ml Penfill 3ml of your own. Please inform your doctor about this, as it may cause withdrawal symptoms. 
  • Novomix 50 100IU/ml Penfill 3ml may decrease the level of potassium, leading to a state of hypokalemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death.
  • Novomix 50 100IU/ml Penfill 3ml is for subcutaneous (under the skin) use only. 
  • If you are switching to a different insulin brand or using a different method of injection, it should be done under strict medical supervision. 
  • Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. 
  • The first symptoms of hyperglycemia (high blood sugar levels) may include excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite, and an acetone odour in the breath. You should closely monitor these symptoms.
  • It is advisable not to consume alcohol, as it may either increase or decrease your blood glucose level. 
  • Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. 
  • Novomix 50 100IU/ml Penfill 3ml is a cold chain medicine, and therefore it must be stored in the refrigerator at a temperature between 2 °C and 8 °C; otherwise, its efficiency may be compromised. Do not store in the freezer or the fridge.
  • It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date. 
  • Novomix 50 100IU/ml Penfill 3ml should not be administered intravenously (into the vein).

Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and for some time after the physical activity.
  • Exercise may also accelerate the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection immediately before running).
  • Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise.
  • Avoid eating sugary foods and opt for cooked foods that are low in calories.
  • When travelling across more than two time zones, consult your doctor about adjusting your insulin schedule.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Caution

You are recommended not to consume alcohol along with Novomix 50 100IU/ml Penfill 3ml to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

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Pregnancy

Safe if prescribed

If you are pregnant or become pregnant follow your doctor's advice about using insulin. During pregnancy controlling diabetes is very important and having high blood sugar may cause problems in both the mother and the baby.

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Breast Feeding

Safe if prescribed

Novomix 50 100IU/ml Penfill 3ml can be given safely to nursing mothers but only under the supervision of a physician.

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Driving

Unsafe

Drive with caution, Novomix 50 100IU/ml Penfill 3ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycemia (low blood sugar).

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Liver

Caution

Novomix 50 100IU/ml Penfill 3ml to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Novomix 50 100IU/ml Penfill 3ml to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Novomix 50 100IU/ml Penfill 3ml can be given safely to children provided; dose has to be prescribed under the supervision of a doctor.

Have a query?

FAQs

Novomix 50 100IU/ml Penfill 3ml is used to treat type 1 & 2 diabetes mellitus. It works by enabling the reuptake of sugar in muscle and fat cells and decreasing sugar production in the liver.

Novomix 50 100IU/ml Penfill 3ml works by replacing the insulin that the body normally produces. Thereby, it helps manage blood sugar levels.

Cold sweat, cool pale skin, headache, rapid heartbeat, nausea, intense hunger, temporary vision changes, drowsiness, unusual tiredness and weakness, nervousness or tremors, feeling anxious, feeling confused, and difficulty concentrating are some of the common signs of low blood sugar levels in an individual.

If you experience low blood sugar, eat glucose tablets or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizzy or drowsy.

It is advisable do not share your insulin device with other persons, even if the needle has been changed. You may give other persons a serious infection or get a severe infection from them.

Novomix 50 100IU/ml Penfill 3ml typically begins working after 10-20 minutes, and its effect will last for at least 24 hours.

Novomix 50 100IU/ml Penfill 3ml is to be injected below the skin (subcutaneously). The best areas to give Novomix 50 100IU/ml Penfill 3ml are on your stomach, upper arm, upper thigh, or buttocks.

Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.

Novomix 50 100IU/ml Penfill 3ml should not be discontinued without a doctor's consultation as stopping Novomix 50 100IU/ml Penfill 3ml may cause severe hypoglycaemia (low blood sugar) and ketoacidosis (buildup of acid in the blood). Consult the doctor if you feel uncomfortable after taking Novomix 50 100IU/ml Penfill 3ml.

The injection site should be changed to prevent skin changes like lumps under the skin. Novomix 50 100IU/ml Penfill 3ml may not work well if injected into the lumpy area.

Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.

Check the label for directions and use Novomix 50 100IU/ml Penfill 3ml as advised by the doctor. Talk to the doctor if you have any concerns. Fill the injection with the appropriate dose. Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin, inject the needle into the skin and then push the plunger in. After injecting the insulin, pull out the needle and dispose of the syringe safely.

Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, have too much or unexpected exercise, eat too little food or are ill.

Symptoms of high blood sugar include feeling thirsty, increased urination, weakness or tiredness, blurred vision and weight loss.

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the usual dose at the scheduled time. Do not use a double dose of Novomix 50 100IU/ml Penfill 3ml.

Novomix 50 100IU/ml Penfill 3ml can be used with other insulins like Insulin isophane or Insulin detemir if prescribed by the doctor.

Opened Novomix 50 100IU/ml Penfill 3ml should be stored at or below 30°C after taking it out of the refrigerator. It can be used up to 4 weeks. Discard opened Novomix 50 100IU/ml Penfill 3ml after 4 weeks even if there is still some medicine left in it.

Avoid reusing the needles to prevent infection and contamination. Always use a new needle for each injection and safely dispose of the used needle.

Country of origin

India

Manufacturer/Marketer address

Plot No.32, 47-50, EPIP Area, Whitefield, Bangalore - 560 066
Other Info - NOV0357

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 7:48 AM IST

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Reference

  1. https://www.drugs.com/mtm/insulin-aspart-and-insulin-aspart-protamine.html
  2. https://www.drugs.com/mtm/insulin-aspart.html

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