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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nucarnit 500 Tablet is used to treat carnitine deficiency and contains Levocarnitine, a substance that helps the body convert fat into energy. It works by restoring low levels of carnitine, which is essential for energy production. Nucarnit 500 Tablet is also used to prevent and treat carnitine deficiency in patients with end-stage kidney disease undergoing dialysis. Some people may experience side effects such as nausea, vomiting, abdominal cramps, or diarrhoea. Before using this medicine, inform your doctor if you are allergic to any of its ingredients, pregnant or breastfeeding, or if you have any pre-existing medical conditions or are taking other medications or supplements.

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Composition :

LEVOCARNITINE-500MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nucarnit 500 Tablet

Nucarnit 500 Tablet belongs to a class of medications known as nutritional supplements and is used to treat carnitine deficiency. Carnitine deficiency occurs when the body does not produce enough carnitine or cannot absorb sufficient amounts from food, even if the diet contains it. Carnitine is essential for energy production, especially in muscles. A deficiency may lead to symptoms such as muscle weakness in the hips, shoulders, upper arms, and legs, as well as fatigue, irritability and delayed motor development, particularly in children.

Nucarnit 500 Tablet contains levocarnitine, which works by replenishing carnitine levels. This natural compound helps transport fatty acids into the mitochondria, the energy-producing parts of cells, where fats are converted into usable energy. This process is essential in tissues that require a significant amount of energy, such as the muscles and heart. Thus, by improving the body’s ability to generate energy, Nucarnit 500 Tablet helps prevent or treat conditions related to carnitine deficiency, such as muscle weakness, fatigue, heart dysfunction, and delayed physical development.

Take Nucarnit 500 Tablet as prescribed by your doctor. You are advised to take Nucarnit 500 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Some people may experience nausea, vomiting, abdominal cramps, and diarrhoea. Most of these side effects of Nucarnit 500 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Before using Nucarnit 500 Tablet , inform your doctor if you are allergic to this medicine or any other medications. It is essential to consult your doctor if you are pregnant or breastfeeding, as the safety of Nucarnit 500 Tablet in such conditions should be assessed by a healthcare professional. You should also tell your doctor if you have a history of seizures, liver or kidney disease, diabetes, or heart problems. Additionally, let your doctor know about any other medications, supplements, or herbal products you are currently taking to avoid potential interactions. Although Nucarnit 500 Tablet is generally considered safe for use in children, it should only be used under medical supervision.

Uses of Nucarnit 500 Tablet

Nucarnit 500 Tablet is used in the treatment of carnitine deficiency. Its detailed uses are as follows:•Primary Systemic Carnitine Deficiency (SPCD): Nucarnit 500 Tablet is used to treat SPCD, an inherited condition that impairs carnitine transport, by restoring carnitine levels in the body.
•Secondary Carnitine Deficiency (SCD): Nucarnit 500 Tablet is used to treat both acute and chronic forms of SCD caused by inborn metabolic disorders (such as propionic acidemia, methylmalonic aciduria, and medium-chain acyl-CoA dehydrogenase deficiency) by promoting the excretion of toxic organic acids.
•Dialysis-Related Deficiency: Nucarnit 500 Tablet helps prevent and treat carnitine deficiency in patients with end-stage renal disease undergoing dialysis.
•Cardiac Support: Nucarnit 500 Tablet helps improve symptoms and enhance exercise capacity in individuals with heart problems.
•Hypothyroidism Symptoms: Nucarnit 500 Tablet helps alleviate symptoms like palpitations (rapid or pounding heartbeat), nervousness, and weakness associated with elevated thyroid hormone levels.
•Male Fertility: Nucarnit 500 Tablet is used alone or in combination with acetyl-L-carnitine to increase sperm count and sperm movement in men with fertility issues.
•Weight Management: Nucarnit 500 Tablet may help reduce body weight, body mass index (BMI), and fat mass, particularly in adults who are overweight or obese.
•Cognitive Support: Nucarnit 500 Tablet may offer benefits in improving cognitive function or slowing cognitive decline in individuals with neurodegenerative diseases (such as Parkinson's disease).

Directions for Use

  • Nucarnit 500 Tablet should be taken with of after meals.
  • It is recommended to follow your doctor's advice.
  • Swallow Nucarnit 500 Tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

Nucarnit 500 Tablet contains the nutritional supplement Levocarnitine, which is used to treat carnitine deficiency, a condition where the body doesn’t have enough carnitine to produce energy from fats. It is beneficial for people on kidney dialysis, as dialysis can lower carnitine levels. By restoring these levels, levocarnitine helps reduce fatigue, muscle weakness, and low blood pressure during dialysis. It also supports heart health by improving energy utilisation in the heart muscles. It may be beneficial in certain genetic or metabolic disorders where the body is unable to process fats properly.

How Nucarnit 500 Tablet Works

Nucarnit 500 Tablet works by increasing carnitine levels in the body, which helps turn fat into energy. Carnitine is essential for muscles and the heart, as it helps move fatty acids into cells, where they are used for energy. When the body lacks sufficient carnitine due to kidney problems, certain medications, or other conditions, Nucarnit 500 Tablet helps restore balance, improving energy and reducing symptoms such as weakness and fatigue.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Nucarnit 500 Tablet

Do not take more than the prescribed dose of Nucarnit 500 Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not use Nucarnit 500 Tablet if you are allergic to it or any of its ingredients. Before starting this medicine, inform your doctor if you have a history of seizures, liver or kidney disease, or diabetes. It is also vital to share details of all medications you are currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements, to avoid potential interactions. Nucarnit 500 Tablet should not be used during pregnancy or breastfeeding unless clearly prescribed by your doctor. Although it is considered safe for children, medical supervision is strongly recommended before use. This medicine contains sucrose; therefore, please inform your doctor if you have any sugar intolerance.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Animal products, such as meat, fish, poultry, and milk, are the best sources.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight through a proper diet and regular exercise.
  • Increase the intake of calcium and magnesium-rich foods, including prunes, raisins, and orange juice.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, and cheese, etc.).
  • Include more vegetables, fruits, low-fat dairy, whole grains and nuts in your diet.
  • Make a habit of regular exercise for at least 30 minutes to 1 hour a day, or at least one should walk for about half an hour for good health.
  • Instead of munching on chips or sweets, opt for unsalted nuts and frozen yoghurt, which are very good for your health.
  • Replace refined carbohydrates-containing foods with whole grain foods and increase the intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.

Habit Forming

No

Therapeutic Class

AMINO ACID SUPPLEMENTS
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Alcohol

Caution

The interaction of alcohol with Nucarnit 500 Tablet is unknown. However, as a precautionary measure, limit or avoid the consumption.

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Pregnancy

Caution

Tell your doctor if you are pregnant or plan to become pregnant. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

There are limited studies of Nucarnit 500 Tablet on breastfeeding women. Please consult your doctor before using Nucarnit 500 Tablet if you are breastfeeding.

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Driving

Safe

Nucarnit 500 Tablet is generally safe to use before driving. However, if you notice any side effects like dizziness, avoid driving and operating machinery until you feel better.

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Liver

Caution

Inform your doctor if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

Inform your doctor if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Nucarnit 500 Tablet can be used in children, but only under the supervision and guidance of a doctor.

Have a query?

FAQs

Nucarnit 500 Tablet is used to treat carnitine deficiency, including in people with kidney disease who are on dialysis. During dialysis, the body can lose significant amounts of carnitine, which is essential for producing energy. On the other hand, some people are unable to absorb enough carnitine from their diet. A lack of carnitine can lead to problems like muscle weakness, tiredness, low blood pressure during dialysis, and heart or liver issues. Nucarnit 500 Tablet helps restore normal carnitine levels in the body and can improve energy, muscle strength, and overall well-being.

Nucarnit 500 Tablet works by increasing carnitine levels in the body, which helps turn fat into energy. Carnitine is essential for muscles and the heart, as it helps move fatty acids into cells, where they are used for energy. When the body lacks sufficient carnitine due to kidney problems, certain medications, or other conditions, Nucarnit 500 Tablet helps restore balance, improving energy and reducing symptoms such as weakness and fatigue.

You are recommended to take Nucarnit 500 Tablet for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with diarrhea, stomach pain, nausea, and vomiting, please consult your doctor.

There are limited studies of Nucarnit 500 Tablet on breastfeeding women. Please consult your doctor before using Nucarnit 500 Tablet if you are breastfeeding. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

The best time to take Nucarnit 500 Tablet is with or after meals, usually 2 to 3 times a day, as directed by your doctor. Taking it with food helps improve absorption and reduces the risk of stomach upset. However, the timing may vary depending on factors such as your medical condition, response to treatment, and other medications you are taking. Always follow your doctor's instructions for the most effective and safe use.

In some patients, warfarin, when taken along with Nucarnit 500 Tablet , may increase the time required for the formation of blood clots. Hence, before starting Nucarnit 500 Tablet , inform your doctor if you are taking warfarin.

The common side effects of Nucarnit 500 Tablet include nausea, vomiting, abdominal cramps, and diarrhoea. Most of these side effects of Nucarnit 500 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - NUC0003

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