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  3. Olumiant 4 mg Tablet 7's

Olumiant 4 mg Tablet 7's, Pack of 1 TABLET
Olumiant 4 mg Tablet 7's, Pack of 1 TABLET
Olumiant 4 mg Tablet 7's, Pack of 1 TABLET
Olumiant 4 mg Tablet 7's, Pack of 1 TABLET
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Olumiant 4 mg Tablet belongs to the class of immunomodulators used in the treatment of rheumatoid arthritis, atopic dermatitis and coronavirus infection. This medicine works by stopping the viral entry into body cells, limits viral replication, and thereby controls the release of cytokines. Common side effects include throat infection, fatigue and high blood cholesterol.

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Composition :

BARICITINIB-4MG

Manufacturer/Marketer :

Eli Lilly and Company (India) Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Olumiant 4 mg Tablet

Olumiant 4 mg Tablet belongs to the group of immunomodulators. Olumiant 4 mg Tablet is used in the treatment of hospitalised cases of coronavirus disease, an infection caused by COVID-19 and is also used to treat Rheumatoid Arthritis. Rheumatoid arthritis is a chronic inflammatory and autoimmune disorder of the joints. Atopic dermatitis is a skin disease in which the skin becomes red, inflamed and itchy.  Coronavirus disease is an infectious disease caused by SARS-CoV-2. It can range from a mild cold to a serious form of pneumonia

Olumiant 4 mg Tablet contains ‘’Baricitinib.’’ Olumiant 4 mg Tablet works by inhibiting viral entry into body cells, limits viral replication and also controls the release of inflammatory mediators called cytokines.

Take Olumiant 4 mg Tablet as prescribed by the doctor. Olumiant 4 mg Tablet may cause certain common side effects such as throat infection, fatigue and high blood cholesterol. Most of these adverse effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to Olumiant 4 mg Tablet or any of its components. Keep your doctor informed if you suffer from any medical disorders. Avoid Olumiant 4 mg Tablet in case of a history of thromboembolism, abdominal disorders such as diverticulitis, cancer, liver disease, chronic infections such as tuberculosis, hepatitis B and C and shingles, and any anaemias. Keep your doctor informed if you have recently had any surgery or are scheduled for surgery in the near future. Offer a detailed medical and vaccination history. Discuss any recent vaccinations with the doctor. Inform the doctor if you are on any other JAK-2 inhibitor medicines, painkillers, steroids and/or drugs that affect the immunity and immune system of the body. Consult your doctor if you are planning to get pregnant or are breastfeeding. Avoid Olumiant 4 mg Tablet use with alcohol.

Uses of Olumiant 4 mg Tablet

Treatment of Rheumatoid Arthritis, Atopic Dermatitis and COVID-19

Directions for Use

Take Olumiant 4 mg Tablet with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Olumiant 4 mg Tablet is an immunomodulator used in the treatment of various types of cancers and infections such as Covid-19. Olumiant 4 mg Tablet contains Baricitinib. Baricitinib works by inhibiting the entry of the virus into the body cells. Olumiant 4 mg Tablet targets an enzyme called Janus kinase (JAK-2), which is responsible for the formation of cytokines. Cytokines are inflammatory mediators. Hence, by inhibiting a cytokine-forming enzyme, Baricitinib reduces the level of cytokines in the body, thus relieving signs of inflammation.  In addition, Baricitinib works by reducing viral replication, thus arresting the progress of the disease.

How Olumiant 4 mg Tablet Works

Olumiant 4 mg Tablet contains ‘’Baricitinib.’’ Olumiant 4 mg Tablet works by inhibiting viral entry into body cells, limits viral replication and also controls the release of inflammatory mediators called cytokines.

Storage

Store in a cool and dry place away from sunlight
Side effects of Olumiant 4 mg Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
  • If you experience symptoms like difficulty breathing, stridor (high-pitched whistling sound when breathing), high fever or chest pain, consult a doctor immediately.
  • Use a nebulizer or a cool-mist humidifier to help loosen mucus and soothe inflamed airway.
  • Drink lots of water to thin mucus and help with coughing.
  • Get enough sleep to allow the body to heal.
  • Suck on lozenges to soothe sore throat.
  • Quit smoking and alcohol consumption.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Olumiant 4 mg Tablet

Never take more than the prescribed dose of Olumiant 4 mg Tablet as it may lead to serious side effects. Patients should promptly seek medical attention and be closely monitored for signs and symptoms of adverse reactions in the event of an overdose. Since there is no known counteragent for Baricitinib, patients ought to receive supportive care.

Drug Warnings

It is advisable to inform the doctor if you are allergic to Olumiant 4 mg Tablet or any of its components. Keep your doctor informed if you suffer from any medical disorders. Avoid Olumiant 4 mg Tablet in case of a history of thromboembolism, abdominal disorders such as diverticulitis, cancer, liver disease, chronic infections such as tuberculosis, hepatitis B and C and shingles, and any anaemias. Keep your doctor informed if you have recently had any surgery or are scheduled for surgery in the near future. Offer a detailed medical and vaccination history. Discuss any recent vaccinations with the doctor. Inform the doctor if you are on any other JAK-2 inhibitor medicines, DMARD’s, painkillers, steroids and/or any drugs that affect the immunity and immune system of the body. Consult your doctor if you are planning to get pregnant or are breastfeeding. Avoid Olumiant 4 mg Tablet use with alcohol.

Drug-Drug Interactions

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BaricitinibCiclosporin
Critical
BaricitinibAzathioprine
Severe

Drug-Drug Interactions

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BaricitinibCiclosporin
Critical
How does the drug interact with Olumiant 4 mg Tablet:
Co-administration of Olumiant 4 mg Tablet with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Ciclosporin with Olumiant 4 mg Tablet is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
BaricitinibAzathioprine
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Coadministration of Olumiant 4 mg Tablet and azathioprine can raise the risk of developing harmful infections.

How to manage the interaction:
Although there is an interaction, Olumiant 4 mg Tablet can be taken with azathioprine if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
BaricitinibOlaparib
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Coadministration of Olumiant 4 mg Tablet and Olaparib can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Olumiant 4 mg Tablet can be taken with Olaparib if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
BaricitinibTacrolimus
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Taking Olumiant 4 mg Tablet and tacrolimus can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Olumiant 4 mg Tablet can be taken with tacrolimus if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your phlegm, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without first talking to your doctor.
BaricitinibPeginterferon alfa-2a
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Coadministration of Peginterferon alfa-2a with Olumiant 4 mg Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Peginterferon alfa-2a with Olumiant 4 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
BaricitinibLomustine
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Using Olumiant 4 mg Tablet together with lomustine may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Olumiant 4 mg Tablet and Lomustine, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - consult a doctor. Do not stop using any medications without talking to a doctor.
BaricitinibDoxorubicin
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Using Olumiant 4 mg Tablet together with Doxorubicin may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Olumiant 4 mg Tablet can be taken with doxorubicin if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
BaricitinibRilonacept
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Using Olumiant 4 mg Tablet together with rilonacept can increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Olumiant 4 mg Tablet can be taken with rilonacept if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
BaricitinibVedolizumab
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Coadministration of Vedolizumab with Olumiant 4 mg Tablet can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Olumiant 4 mg Tablet and Vedolizumab, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
BaricitinibLeflunomide
Severe
How does the drug interact with Olumiant 4 mg Tablet:
Coadministration of Olumiant 4 mg Tablet and leflunomide can raise the risk of infections.

How to manage the interaction:
Although there is an interaction, Olumiant 4 mg Tablet can be taken with leflunomide if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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BARICITINIB-4MGHigh fat foods
Mild

Drug-Food Interactions

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BARICITINIB-4MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Coadministration of Olumiant 4 mg Tablet and high-fat meals can decrease the absorption of Olumiant 4 mg Tablet. Avoid fatty food and oily food while being treated with Olumiant 4 mg Tablet.

Diet & Lifestyle Advise

  • Keep a healthy state of mind. Fear is the one of the biggest causes of decreased immunity. See a therapist if you feel the need. 

  • Meditation, music and yoga have also proven very effective in helping with mental health.

  • Keep yourself at a safe distance from people.

  • Always sneeze or cough into your elbow and keep a handkerchief on you.

  • Wash your hands with soap and water and keep yourself clean.

  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. Load up on Vitamin-C rich citrus fruit for enhanced immunity.

  • Do not forget to take your Vitamin B complex and Vitamin C supplements every day as these are essential for the body and immunity.

  • Steam inhalation for 3-5 minutes every day and salt-water gargle with warm water has been proven very effective in keeping respiratory infections at bay and in promoting health. 

  • Avoid taking Olumiant 4 mg Tablet with alcohol as there may be an interaction.

  • Stay hydrated by drinking plenty of water as dehydration is often seen in pneumonia.

  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. Doing weight-bearing exercises can prove very helpful in promoting bone health.

  • Avoid tobacco use as smoking hampers lung health and makes breathing even more difficult.

  • Spend time under the sun (however with proper sunscreen) for quality intake of Vitamin D. Vitamin D is necessary for the absorption of Calcium, which is the most important component of bones and can help with bone and joint pain.

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Olumiant 4 mg Tablet Substitute

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Product Substitutes

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Alcohol

Caution

It is not recommended to use alcohol with Olumiant 4 mg Tablet. Please consult your doctor if you have any concerns.

bannner image

Pregnancy

Unsafe

Olumiant 4 mg Tablet is absolutely contraindicated during pregnancy.

bannner image

Breast Feeding

Caution

Not enough studies exist to ascertain the effect of Olumiant 4 mg Tablet on nursing. Olumiant 4 mg Tablet is not recommended to use without contraception during and for at least 1 week after treatment. Please consult your doctor in case of any concerns.

bannner image

Driving

Safe if prescribed

Olumiant 4 mg Tablet does not affect your ability to drive.

bannner image

Liver

Caution

Exercise caution before using Olumiant 4 mg Tablet in case of established liver disease as it may cause a derangement of liver enzymes. Please consult your doctor to address any concerns.

bannner image

Kidney

Caution

Exercise caution before using Olumiant 4 mg Tablet in case of established kidney disease. Please consult your doctor to address any concerns.

bannner image

Children

Caution

Not enough studies exist to ascertain the effect of Olumiant 4 mg Tablet in children. Please consult your doctor in case of any concerns.

Have a query?

FAQs

Olumiant 4 mg Tablet belongs to the group of immunomodulators. It is used in the treatment of hospitalised cases of coronavirus disease, an infection caused by COVID-19 and is also used to treat Rheumatoid Arthritis.

Olumiant 4 mg Tablet works by preventing the virus from attaching to the body’s cell receptors and thereby blocking its entry and spread.

If you suffer from Chronic Kidney Disease, please consult with your doctor before using Olumiant 4 mg Tablet and discuss any concerns with them. Olumiant 4 mg Tablet is to be used with caution in those suffering from kidney and liver problems.

Not enough literature exists to ascertain the effects of Olumiant 4 mg Tablet on fertility. However, Olumiant 4 mg Tablet should be absolutely avoided in pregnancy. Please consult your doctor in case of any concerns.

Advanced age, obesity, chronic kidney disease, lung disease, sickle cell disease, neurodevelopmental disorders (for example cerebral palsy) and diseases of metabolism are some risk factors for disease progression.

If you have liver problems, you should consult a healthcare practitioner before using Baricitinib. Baricitinib may impair liver function, so your doctor will need to analyze your specific circumstances to determine whether the benefits exceed risk.

While Olumiant 4 mg Tablet has not been directly related to cancer, you should discuss any potential concerns with your doctor. They can give you with information based on the most recent research and your individual health needs.

Before starting Olumiant 4 mg Tablet, your doctor may recommend certain investigations to assess your overall health and to monitor for any potential side effects. These may include blood tests, liver function tests, and other assessments as needed.

Country of origin

India

Manufacturer/Marketer address

Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, Haryana, India
Other Info - OLU0002

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:46 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.youtube.com/watch?v=UjhLJZZ-uo0
  2. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-drug-combination-treatment-covid-19
  3. https://reference.medscape.com/drug/olumiant-baricitinib-1000107
  4. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00331-3/fulltext
  5. https://en.wikipedia.org/wiki/Baricitinib#Mechanism_of_action
  6. https://www.ema.europa.eu/en/documents/product-information/olumiant-epar-product-information_en.pdf
  7. https://www.medicines.org.uk/emc/product/2434/smpc#PREGNANCY
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