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  3. Omez-40 Tablet 10's

Omez-40 Tablet 10's, Pack of 10 TABLETS
Omez-40 Tablet 10's, Pack of 10 TABLETS
Omez-40 Tablet 10's, Pack of 10 TABLETS
Omez-40 Tablet 10's, Pack of 10 TABLETS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Omez-40 Tablet is used to treat gastroesophageal reflux disease (GERD), stomach ulcer, and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour). It contains Omeprazole, which helps reduce stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn. It may cause common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

OMEPRAZOLE-40MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Omez-40 Tablet

Omez-40 Tablet belongs to the class of drugs known as proton pump inhibitors (PPIs) used to treat gastroesophageal reflux disease (GERD), stomach ulcer, and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour). Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in the long run, it gets eroded by excessive stomach acid production, leading to complications like GERD, peptic ulcer, and Zollinger-Ellison syndrome.

Omez-40 Tablet contains omeprazole, which helps reduce stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the stomach wall cells and is responsible for releasing gastric acid secretion. Omez-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Omez-40 Tablet may cause common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. These side effects are temporary and may be resolved after some time. However, if the side effects persist or worsen, contact the doctor.

Omez-40 Tablet should not be given to the patient suffering from Clostridium difficile-associated diarrhoea. Consult the doctor if you are pregnant or breastfeeding. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to any components in Omez-40 Tablet , or will have an endoscopy in the future. Ask your doctor if you should stop taking Omez-40 Tablet a few weeks before your endoscopy as it may hide some of the problems that would be spotted during an endoscopy. Prolonged use of Omez-40 Tablet may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine due to loss of magnesium. Avoid using Omez-40 Tablet with St John’s Wort (plant-based antidepressant), rifampin (antibiotic) and methotrexate (anti-cancer and anti-arthritis medicine) due to the severe drug interaction.

Uses of Omez-40 Tablet

Omez-40 Tablet is used to treat Stomach ulcers, Acid reflux (GERD), Hyperacidity, and Zollinger-Ellison syndrome. The detailed uses of Omez-40 Tablet are as follows:
• Acid reflux treatment: Omez-40 Tablet is a proton pump inhibitor (PPI) that reduces stomach acid production, providing relief from acid reflux symptoms. It is commonly used to treat conditions like gastroesophageal reflux disease (GERD).
• Hyperacidity: Omez-40 Tablet helps to relieve hyperacidity by reducing the production of stomach acid.
• Dyspepsia relief: Omez-40 Tablet provides relief from dyspepsia symptoms like bloating, heartburn, and stomach pain by reducing stomach acid.
• Zollinger-Ellison syndrome: Omez-40 Tablet can also be prescribed to treat Zollinger-Ellison syndrome, which helps control acid production and manage symptoms.
• Prevention of stomach ulcers: Omez-40 Tablet prevents stomach ulcers by reducing acid and promoting healing.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Omez-40 Tablet is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome, stomach ulcers. Omez-40 Tablet works by irreversibly blocking the proton pump gate (which secretes stomach acid). 

How Omez-40 Tablet Works

Omez-40 Tablet contains omeprazole, which helps reduce stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the stomach wall cells and is responsible for releasing gastric acid secretion. Omez-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Storage

Store in a cool and dry place away from sunlight
Side effects of Omez-40 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

What if I have taken an overdose of Omez-40 Tablet

Do not take more than the prescribed dose of Omez-40 Tablet as it may cause overdose. The symptoms of overdose include blurred vision, confusion, drowsiness, vomiting, nausea, sweating, fast or pounding heartbeat, flushing (feeling of warmth), headache and dry mouth. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Omez-40 Tablet should not be given to the patient suffering from Clostridium difficile-associated diarrhoea. Consult the doctor if you are pregnant or breastfeeding. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Omez-40 Tablet or will have an endoscopy in the future. Ask your doctor if you should stop taking Omez-40 Tablet a few weeks before your endoscopy as it may hide some of the problems that would be spotted during an endoscopy. Prolonged use of Omez-40 Tablet may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine due to loss of magnesium. Avoid using Omez-40 Tablet with St John’s Wort (plant-based antidepressant), rifampin (antibiotic) and methotrexate (anti-cancer and anti-arthritis medicine) due to the severe drug interaction.

Drug-Drug Interactions

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OmeprazoleErlotinib
Critical
OmeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OmeprazoleErlotinib
Critical
How does the drug interact with Omez-40 Tablet:
Omez-40 Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Omez-40 Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleRilpivirine
Critical
How does the drug interact with Omez-40 Tablet:
Using rilpivirine together with Omez-40 Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking Omez-40 Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
OmeprazoleItraconazole
Severe
How does the drug interact with Omez-40 Tablet:
Co-administration of Omez-40 Tablet with itraconazole can lessen the amount or effects of itraconazole.

How to manage the interaction:
Although taking Itraconazole along with Omez-40 Tablet can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
OmeprazoleNelfinavir
Severe
How does the drug interact with Omez-40 Tablet:
Using Omez-40 Tablet in conjunction with nelfinavir can reduce the effectiveness of nelfinavir.

How to manage the interaction:
Although taking Omez-40 Tablet with nelfinavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleCarbamazepine
Severe
How does the drug interact with Omez-40 Tablet:
Taking Omez-40 Tablet and carbamazepine may possibly reduce the effects of Omez-40 Tablet, which could reduce its capacity to treat the condition.

How to manage the interaction:
Although taking Omez-40 Tablet and carbamazepine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without consulting a doctor.
OmeprazoleTacrolimus
Severe
How does the drug interact with Omez-40 Tablet:
Taking tacrolimus with Omez-40 Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk of serious side effects (high sugars, infections, kidney problems, hyperkalemia - high blood levels of potassium).

How to manage the interaction:
Although taking Omez-40 Tablet with tacrolimus can lead to interaction, they can be taken if recommended by a doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations (fast heartbeat), muscle spasm, tremor (shaking of hands & legs), and seizures(fits). Do not stop using any medications without talking to a doctor.
OmeprazoleIsoniazid
Severe
How does the drug interact with Omez-40 Tablet:
When Omez-40 Tablet is taken with Isoniazid, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Omez-40 Tablet with Isoniazid can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleMesalazine
Severe
How does the drug interact with Omez-40 Tablet:
Co-administration of Omez-40 Tablet with mesalazine can decrease the effects of mesalazine.

How to manage the interaction:
There could be a possible interaction between Mesalazine and Omez-40 Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
OmeprazoleAcalabrutinib
Severe
How does the drug interact with Omez-40 Tablet:
Omez-40 Tablet, through decreasing stomach acidity, may interfere with the absorption of acalabrutinib capsules and reduce their effectiveness.

How to manage the interaction:
Although taking Omez-40 Tablet with acalabrutinib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleClopidogrel
Severe
How does the drug interact with Omez-40 Tablet:
When taken together Omez-40 Tablet can lower the levels of Clopidogrel in the blood, which can result in a decreased effectiveness of clopidogrel.

How to manage the interaction:
Taking Omez-40 Tablet and clopidogrel together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Omez-40 Tablet Substitute

Substitutes safety advice

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Product Substitutes

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Alcohol

Caution

Drinking alcohol with Omez-40 Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Omez-40 Tablet .

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Pregnancy

Caution

It is not known whether Omez-40 Tablet affects the baby or not. So, contact a doctor before taking Omez-40 Tablet if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Omez-40 Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before taking Omez-40 Tablet if you are breastfeeding. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

In some cases, Omez-40 Tablet may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Caution

Omez-40 Tablet should be taken with precaution in patients with liver disease.

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Kidney

Caution

Patients with kidney disease should consult a doctor before taking Omez-40 Tablet .

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Children

Caution

Omez-40 Tablet should not be prescribed for children under 1 years of age. Omez-40 Tablet is generally prescribed from 1-12 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

Have a query?

FAQs

Omez-40 Tablet is used to treat gastroesophageal reflux disease (GERD), stomach/peptic ulcer, and Zollinger-Ellison syndrome (overproduction of acid due to the pancreatic tumour).

Omez-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Prolonged intake of Omez-40 Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long-term side effects.

No. Omez-40 Tablet is not prescribed for stomach cancer. Omez-40 Tablet is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.

Yes. Omez-40 Tablet can alter certain medical tests like neuroendocrine tumours (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostic tests, contact your doctor.

No. Omez-40 Tablet prevents excess production of stomach acid, causing acid reflux and heartburn. If you notice blood in your stool or mucous, immediately contact the doctor.

You’ll usually take Omez-40 Tablet once a day, first thing in the morning. It will not affect your stomach, so you can take it with or without food.

Yes, you can take Omez-40 Tablet with domperidone, however it should be taken only of recommended by the doctor.

Before taking any medication including Omez-40 Tablet , it's important to consult with a doctor. They can assess your individual needs and provide customized advice. Follow the instructions provided by your healthcare professional and be aware of potential adverse effects. If you have any concerns, don't hesitate to ask for clarification.

Diarrhea is a possible side effect of omeprazole. It's often mild and short-lived, but if it's severe or accompanied by other symptoms, please see your doctor.

The duration of omeprazole treatment is individualized and depends on your specific condition and response to the medication.

Omeprazole can increase the risk of calcium deficiency and osteoporosis if taken for a long time. This is because it can interfere with calcium absorption. If you're taking omeprazole for a long time, talk to your doctor about the risks and benefits.

Yes, long-term use of Omez-40 Tablet may increase the risk of vitamin deficiencies, particularly vitamin B12. If you have any concerns or face any adverse effects related to vitamin deficiencies, please consult your doctor.

The decision to prescribe omeprazole to cardiac patients should be made individually, taking into account their medical history and risk factors.

Swallow it whole with a glass of water; do not crush, chew, or break it.

No, it is recommended not to crush, chew, or break.

Omez-40 Tablet may cause common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhea, and headache. These side effects are temporary and may be resolved after some time. However, if the side effects persist or worsen, contact the doctor.

Before taking the Omez-40 Tablet , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Yes, Omez-40 Tablet can interact with other medications. It's important to inform your doctor about all the medications you're taking, including prescription medications, over-the-counter drugs and herbal supplements.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - OME0004

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 14, 2025 | 2:34 PM IST

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Reference

  1. https://www.nhs.uk/medicines/omeprazole/
  2. https://www.medicines.org.uk/emc/product/5944/smpc#gref
  3. https://www.medicines.org.uk/emc/files/pil.5944.pdf
  4. https://www.drugs.com/omeprazole.html
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