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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Omnacortil-40 Tablet is used to prevent or treat organ rejection, symptoms of asthma, and nephrotic syndrome. Besides this, it may also be indicated to treat inflammation caused by illness or injury. It helps treat nephrotic syndrome by removing the protein and extra water in the urine. It helps prevent asthma attacks and controls symptoms like wheezing. Prednisolone prevents organ rejection by suppressing the body’s immune response.

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Whats That

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Synonym :

PREDNISOLONE SODIUM PHOSPHATE

Composition :

PREDNISOLONE-40MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Omnacortil-40 Tablet

Omnacortil-40 Tablet is indicated to prevent or treat organ rejection, symptoms of asthma, and nephrotic syndrome. It may also be used to treat inflammation caused by illness or injury.

Omnacortil-40 Tablet contains Prednisolone, which helps treat nephrotic syndrome by removing the protein and extra water in the urine. It helps prevent asthma attacks and controls symptoms like wheezing. Prednisolone prevents organ rejection by suppressing the body’s immune response.

In some cases, Omnacortil-40 Tablet may cause side effects such as nausea, vomiting, weight gain, and stomach upset. Most of these side effects may not require medical attention and resolve gradually over time. However, consult the doctor if the side effects persist or worsen.

Let the doctor know if your child is allergic to any of the components in Omnacortil-40 Tablet . Keep the doctor informed about your child’s health condition and medications to rule out any side effects/interactions.

Uses of Omnacortil-40 Tablet

Omnacortil-40 Tablet is used for Immunosuppression/prevention of Organ rejection, Asthma, Nephrotic syndrome, and Inflammation. The detailed uses of Omnacortil-40 Tablet are as follows:
• Allergic Reactions: Omnacortil-40 Tablet alleviates allergic reactions by reducing inflammation and relieving symptoms like rashes and hives.
• Asthma Management: Omnacortil-40 Tablet helps to manage asthma by reducing airway inflammation, improving breathing.
• Autoimmune Conditions: Omnacortil-40 Tablet treats autoimmune conditions like lupus and rheumatoid arthritis by reducing immune system activity and inflammation.
• Nephrotic syndrome: Omnacortil-40 Tablet treats nephrotic syndrome by reducing protein loss, inflammation, and immune system activity, helping alleviate symptoms.
• Gastrointestinal Disorders: Omnacortil-40 Tablet manages gastrointestinal disorders like Crohn's disease and ulcerative colitis by reducing digestive tract inflammation.
• Skin Disorders: Omnacortil-40 Tablet treats skin conditions like eczema and psoriasis by reducing inflammation, redness, itching, and swelling.

Directions for Use

  • Omnacortil-40 Tablet can be taken with meals to reduce stomach irritation and improve absorption.
  • It is usually given once daily, preferably in the morning with breakfast, or as advised by the doctor.
  • Check the label for directions before using this medication.
  • Shake the bottle well before use.
  • Give the prescribed dose to your child by mouth using the measuring cup provided with the pack.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Omnacortil-40 Tablet contains Prednisolone, a corticosteroid and immunosuppressant used to prevent or treat organ rejection, symptoms of asthma, and nephrotic syndrome. Besides this, it may also be indicated to treat inflammation caused by illness or injury. Omnacortil-40 Tablet helps treat nephrotic syndrome by removing the protein and extra water in the urine. It helps prevent asthma attacks and controls symptoms like wheezing. Prednisolone prevents organ rejection by suppressing the body’s immune response.

How Omnacortil-40 Tablet Works

Omnacortil-40 Tablet contains Prednisolone, which helps treat nephrotic syndrome by removing the protein and extra water in the urine. It helps prevent asthma attacks and controls symptoms like wheezing. Prednisolone prevents organ rejection by suppressing the body’s immune response.

Storage

Store in a cool and dry place away from sunlight
Side effects of Omnacortil-40 Tablet
  • Avoid diet rich in salt and carbohydrates
  • Drink plenty of water and stay hydrated.
  • Exercise regularly and maintain a healthy lifestyle.
  • Take potassium rich foods like potatoes, spinach, tomatoes, sea food and dairy products.
  • Take beverages containing caffeine like coffee and tea.
  • Consult your doctor if you experience severe symptoms like high blood sugar, increased thirst, urination, or blurred vision to check if your medication is the cause.
  • Your doctor may adjust your medications to reduce the risk of impaired blood sugar regulation.
  • Eat a balanced diet rich in whole foods like fruits, vegetables, whole grains, and lean proteins.
  • Protein and healthy fats, such as avocado, almonds, and seeds, can help manage blood sugar levels.
  • Limit added sugars from sugary drinks, baked goods, and candy.
  • To maintain your blood sugar levels within a healthy range, check them frequently.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.

What if I have taken an overdose of Omnacortil-40 Tablet

Do not take more than the prescribed dose. Symptoms of an overdose may include Altered mental status with agitation (psychosis), Burning or itching skin, Convulsions (seizures), Deafness, Depression and Worsening of health conditions. If you suspect that you or anyone else who may have overdosed of Omnacortil-40 Tablet , please go to the emergency department of the closest hospital.

Drug Warnings

Do not administer Omnacortil-40 Tablet if the child is allergic to any of its components. Inform the doctor if the child has liver or kidney problems, tuberculosis, high blood pressure, thyroid problems, seizures or diabetes. Let the doctor know if your child takes other medications, including supplements or herbal products.

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Omnacortil-40 Tablet:
Co-administration of Iohexol and Omnacortil-40 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Omnacortil-40 Tablet with Iohexol is not generally advised as they can lead to an interaction, they can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Omnacortil-40 Tablet:
Co-administration of Omnacortil-40 Tablet and Desmopressin may increase the risk of hyponatremia (low levels of sodium in the blood).

How to manage the interaction:
Taking Omnacortil-40 Tablet with Desmopressin is not generally advised as they lead to an interaction, they can be taken together if advised by a doctor. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Omnacortil-40 Tablet:
When Mifepristone is taken with Omnacortil-40 Tablet, the effects of Omnacortil-40 Tablet might be considerably reduced, which may be less effective in treating your condition.

How to manage the interaction:
Taking Omnacortil-40 Tablet with Mifepristone is not recommended, they can be taken together if advised by a doctor. Do not discontinue the medication without consulting a doctor.
PrednisoloneBCG vaccine
Critical
How does the drug interact with Omnacortil-40 Tablet:
When BCG vaccine is used with Omnacortil-40 Tablet, its effectiveness may be reduced.

How to manage the interaction:
Taking Omnacortil-40 Tablet with BCG vaccine is not generally advised, but they can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Omnacortil-40 Tablet:
Taking Omnacortil-40 Tablet with Vigabatrin, especially over long periods, may increase the risk of severe side effects, including eyesight loss.

How to manage the interaction:
Although taking Omnacortil-40 Tablet with Vigabatrin together can result in an interaction, it can be taken if a doctor has prescribed it. A routine vision test is necessary during this treatment. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Omnacortil-40 Tablet:
Bupropion is capable of causing seizures (fits) and combining it with Omnacortil-40 Tablet, may enhance the risk.

How to manage the interaction:
Although taking Omnacortil-40 Tablet and Bupropion together can result in an interaction, it can be taken if a doctor has prescribed it. You should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
PrednisoloneCertolizumab
Severe
How does the drug interact with Omnacortil-40 Tablet:
Taking Omnacortil-40 Tablet with Certolizumab can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Omnacortil-40 Tablet and Certolizumab, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Omnacortil-40 Tablet:
Co-administration of Nalidixic acid may cause tendinitis and tendon rupture, and the risk may be increased when combined with Omnacortil-40 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Omnacortil-40 Tablet and Nalidixic acid, but it can be taken if prescribed by a doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking bempedoic acid and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Omnacortil-40 Tablet:
Co-administration of Norfloxacin may cause tendinitis (inflammation of a tissue that attaches muscle to bone) and tendon rupture, and the risk may be increased when combined with Omnacortil-40 Tablet. People over the age of 60 and people who have had a kidney, heart, or lung transplant may be especially at risk.

How to manage the interaction:
Although there is an interaction, Omnacortil-40 Tablet can be taken with Norfloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, stop taking norfloxacin and consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Omnacortil-40 Tablet:
Co-administration of Moxifloxacin may cause tendinitis (inflammation of a tissue that attaches muscle to bone) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Omnacortil-40 Tablet can be taken with Moxifloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area (back of the ankle, biceps, shoulder, hand, or thumb), consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fruits and vegetables in the child’s diet.
  • Make sure the child is well-rested and stays hydrated.
  • Do not let the child consume large amounts of soft drinks, tea, coffee, or chocolate drinks.
  • Encourage your child to stay physically active.
  • Limit their intake of high-calorie food such as cakes, sweets or crisps.

Habit Forming

No

Therapeutic Class

CORTICOSTEROIDS

Omnacortil-40 Tablet Substitute

Substitutes safety advice
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

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Liver

Consult your doctor

Please consult the doctor if your child has liver problems.

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Kidney

Consult your doctor

Please consult the doctor if your child has kidney problems.

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Children

Safe if prescribed

Omnacortil-40 Tablet can be given to children if prescribed by the doctor.

Have a query?

FAQs

Omnacortil-40 Tablet is used for Immunosuppression/prevention of Organ rejection, Asthma, Nephrotic syndrome, and Inflammation.

Omnacortil-40 Tablet works by removing the protein and the extra water in the urine. It prevents organ rejection by suppressing the body's immune response.

To treat the child's condition effectively, completing the course of Omnacortil-40 Tablet is recommended even if the child feels well. Talk to the doctor if you have any concerns.

If you miss giving a dose to the child, administer the missed dose as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and administer the next dose at the scheduled time. Avoid doubling the dose.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - OMN0004

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