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Onco-BCG 40 mg Injection is a vaccine used to prevent tuberculosis. Tuberculosis is an infectious respiratory disease that affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. It contains a weakened bacteria that is used to prevent tuberculosis. It is administered only to those individuals who have not previously been infected with Mycobacterium tuberculosis and are at high risk of exposure.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Onco-BCG 40 mg Injection

Onco-BCG 40 mg Injection is a vaccine belonging to the class of immunizing agents. It is used to prevent tuberculosis. Tuberculosis is an infectious respiratory disease that affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Onco-BCG 40 mg Injection is also used to stop bladder cancer from spreading into the deeper layers of the bladder.

Onco-BCG 40 mg Injection is a Bacillus of Calmette-Guerin (BCG) live attenuated vaccine form of Mycobacterium bovis, used to prevent tuberculosis. It is given to individuals who are not previously infected with Mycobacterium tuberculosis and are at high risk for exposure.

Onco-BCG 40 mg Injection may cause certain common side effects, such as redness and soreness at the site of injection, injection site reactions, and ulceration at the vaccination site. Most of these side effects will last for only a few days and resolve by themselves. A trained healthcare doctor will administer Onco-BCG 40 mg Injection in the hospital.

Inform the doctor if you/your child develops any allergic reactions to the previous dose if received, has a known pre-existing allergy to any of the contents of Onco-BCG 40 mg Injection or has had a severe allergic reaction following a previous dose of Onco-BCG 40 mg Injection. Let your doctor know about your detailed medical history, including any chronic disease, neurological disease, or severe illness. It is important to inform the doctor about your vaccination history.

Uses of Onco-BCG 40 mg Injection

Onco-BCG 40 mg Injection is used in the Prevention of Tuberculosis. The detailed use of Onco-BCG 40 mg Injection is as follows:

  • Prevention of Tuberculosis: Onco-BCG 40 mg Injection is indicated for protecting against tuberculosis in high-risk groups, such as infants, children, and healthcare workers frequently exposed to Mycobacterium tuberculosis, thereby reducing the incidence of severe forms of TB like meningitis.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Onco-BCG 40 mg Injection will be administered by a healthcare professional.
  • Do not self-administer it.

Key Benefits

Onco-BCG 40 mg Injection is a Bacillus of Calmette-Guerin (BCG) live attenuated vaccine form of Mycobacterium bovis. It contains a weakened bacteria that is used to prevent tuberculosis. Onco-BCG 40 mg Injection is administered only to those individuals who have not previously been infected with Mycobacterium tuberculosis and are at high risk of exposure.

How Onco-BCG 40 mg Injection Works

Onco-BCG 40 mg Injection is a Bacillus of Calmette-Guerin (BCG) live attenuated vaccine form of Mycobacterium bovis, used to prevent tuberculosis. Onco-BCG 40 mg Injection stimulates the immune system to fight Mycobacterium tuberculosis (TB prevention) or bladder cancer cells (bladder cancer treatment). It is given to individuals who are not previously infected with Mycobacterium tuberculosis and are at high risk for exposure.

Storage

Store in a cool and dry place away from sunlight
Side effects of Onco-BCG 40 mg Injection
  • Painful urination can be reduced by drinking lots of water.
  • Don't hold urine, as it can worsen the pain during urination.
  • Try taking probiotics and eating garlic, which can help reduce painful urination.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet and avoid bladder-irritating foods.
  • Quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.
  • Bladder infection needs immediate medical attention when you observe blood in urine or have any abnormal changes in your body.
  • Get a physical examination and blood tests to identify factors that led to infection and initiate the treatment process immediately.
  • Avoid anxiety and stress, as it can worsen your condition.
  • Follow your doctor's instructions, and there can be medication with antibiotics and other supportive vitamins.
  • Take a balanced diet to prevent negative changes in your body.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Onco-BCG 40 mg Injection

As Onco-BCG 40 mg Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Avoid receiving Onco-BCG 40 mg Injection if you or your child have any known hypersensitivity reactions to a previous dose of Onco-BCG 40 mg Injection or any of its components. It is contraindicated in patients with positive tuberculin tests, patients with active TB disease, impaired immune responses because of HIV infections, congenital immunodeficiencies, leukaemia, lymphoma, and other malignancies. Hence, patients should be observed carefully after receiving the vaccine. This medicine is not intended for use in infants, children, or adults with severe immune deficiency syndromes. Also, children with a family history of weak immune systems should avoid receiving the vaccination. Inform the doctor about any medications that you/your child is currently taking and about any previous vaccination and medical history. Pregnant and breastfeeding mothers should inform their doctor before administering Onco-BCG 40 mg Injection.

Drug-Drug Interactions

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BCG vaccineAmikacin
Critical
BCG vaccineSirolimus
Critical

Drug-Drug Interactions

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BCG vaccineAmikacin
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Coadministration of Onco-BCG 40 mg Injection with Amikacin can reduce its effectiveness.

How to manage the interaction:
Taking Amikacin with the Onco-BCG 40 mg Injection can result in an interaction. Furthermore, if you have active TB, you should not undergo BCG therapy. However, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
BCG vaccineSirolimus
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Coadministration of Sirolimus with the Onco-BCG 40 mg Injection can make the vaccine less effective.

How to manage the interaction:
Taking Sirolimus with the Onco-BCG 40 mg Injection is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Co-administration of Onco-BCG 40 mg Injection with Dimethyl fumarate can increase the risk of infection.

How to manage the interaction:
Taking Dimethyl fumarate with the Onco-BCG 40 mg Injection can possibly lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without a doctor's advice.
BCG vaccineMelphalan
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Co-administration of the Onco-BCG 40 mg Injection with Melphalan together can increase the risk or severity of infection or reduces the effectiveness of the vaccine.

How to manage the interaction:
Taking Melphalan with the Onco-BCG 40 mg Injection is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medication without consulting your doctor.
BCG vaccineLenalidomide
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Combining the Onco-BCG 40 mg Injection with Lenalidomide increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenalidomide with Onco-BCG 40 mg Injection is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
BCG vaccineFludrocortisone
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Coadministration of Fludrocortisone with Onco-BCG 40 mg Injection can increase the risk of serious infections.

How to manage the interaction:
Taking Fludrocortisone with Onco-BCG 40 mg Injection is not recommended, but can be taken if doctor has prescribed it. but can be taken if doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
BCG vaccineMercaptopurine
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Co-administration of the Onco-BCG 40 mg Injection with Mercaptopurine together can increase the risk of infection.

How to manage the interaction:
Taking Mercaptopurine with Onco-BCG 40 mg Injection is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
BCG vaccineCefoperazone
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
When Onco-BCG 40 mg Injection is used with Cefoperazone, its effectiveness may be reduced.

How to manage the interaction:
Taking cefoperazone with Onco-BCG 40 mg Injection is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor
BCG vaccineTrimethoprim
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Taking trimethoprim with Onco-BCG 40 mg Injection can reduce the effectiveness of the Onco-BCG 40 mg Injection

How to manage the interaction:
Although there is an interaction between trimethoprim and Onco-BCG 40 mg Injection is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
BCG vaccinePazopanib
Critical
How does the drug interact with Onco-BCG 40 mg Injection:
Taking Onco-BCG 40 mg Injection with Pazopanib can increase the risk of infection.

How to manage the interaction:
Taking Pazopanib with Onco-BCG 40 mg Injection is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Apply an ice pack on the injection site in case of pain or soreness.
  • It is important to keep your child hydrated post-vaccination. Make sure to give them plenty of water. 
  • In case of fever, consult your doctor before treating with any OTC medication.
  • Ensure a balanced diet for proper nourishment and immunity.
  • Keep your child's immunisations up to date.

Habit Forming

No

Therapeutic Class

[IMMUNIZING AGENTS]

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Alcohol

Consult your doctor

It is not known whether alcohol can be consumed when you are taking Onco-BCG 40 mg Injection. Please consult your doctor.

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Pregnancy

Caution

If you are pregnant or planning to be pregnant, inform your doctor before receiving Onco-BCG 40 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Onco-BCG 40 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Safe

Onco-BCG 40 mg Injection may not affect your ability to drive. However, do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Caution

Inform your doctor if the patient has liver problems before receiving the vaccination. Your doctor will decide whether a dosage adjustment is needed.

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Kidney

Caution

Inform your doctor if the patient has kidney impairment before receiving the vaccination. Your doctor will decide whether a dosage adjustment is needed.

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Children

Safe if prescribed

Onco-BCG 40 mg Injection is safe for use in children below 12 years of age. Please consult your doctor if you have any concerns. For children, Onco-BCG 40 mg Injection should be given in the deltoid region. Administration via intravenous, intramuscular, intradermal, and subcutaneous routes is not recommended.

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Heart

Please consult your doctor before receiving Onco-BCG 40 mg Injection if you have pre-existing heart problems. Your doctor will prescribe Onco-BCG 40 mg Injection if the benefits outweigh the risks.

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Geriatrics

Safe if prescribed

Onco-BCG 40 mg Injection is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

FAQs

Onco-BCG 40 mg Injection is a Bacillus of Calmette-Guerin (BCG) live attenuated vaccine form of Mycobacterium bovis, used to prevent tuberculosis.

Onco-BCG 40 mg Injection may rarely cause injection site reactions. However, if the condition persists for longer or worsens, consult a doctor.

Onco-BCG 40 mg Injection causes side effects such as soreness, tenderness, allergic reactions, pain at the site of injection, vomiting, blood in urine, and redness at the site of injection. Please contact a doctor if any of these side effects persist for longer durations.

Yes, Onco-BCG 40 mg Injection can lead to blood in the urine, as a common side effect, especially after bladder cancer treatment. If it continues or is severe, contact a doctor.

No, it is not safe to have intercourse (sex) for at least 24 hours following each Onco-BCG 40 mg Injection treatment. You are recommended to use a condom for one week after the therapy to prevent the sexual transmission of BCG bacteria. Please contact a doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ONC0012

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