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  3. Ondem 4 Tablet 10's

Ondem 4 Tablet 10's, Pack of 10 TABLETS
Ondem 4 Tablet 10's, Pack of 10 TABLETS
Ondem 4 Tablet 10's, Pack of 10 TABLETS
Ondem 4 Tablet 10's, Pack of 10 TABLETS
Ondem 4 Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ondem 4 Tablet is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment or surgery. It contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause side effects such as feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ondem 4 Tablet

Ondem 4 Tablet belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Ondem 4 Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondem 4 Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Ondem 4 Tablet as prescribed. Your doctor will advise you on how often you take Ondem 4 Tablet based on your medical condition. A person taking Ondem 4 Tablet often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Ondem 4 Tablet , and even some of the unpleasant effects of Ondem 4 Tablet do not require medical attention.

The use of Ondem 4 Tablet is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Ondem 4 Tablet should be used during pregnancy or breastfeeding after consulting a doctor. Ondem 4 Tablet contains lactose so tell your doctor if you have an intolerance to some sugars.

Uses of Ondem 4 Tablet

Ondem 4 Tablet is used in the prevention of Nausea and Vomiting. The detailed uses of Ondem 4 Tablet are as follows:
•Chemotherapy-Induced Nausea: Ondem 4 Tablet is frequently prescribed to alleviate nausea and vomiting caused by chemotherapy treatments.
•Radiation Therapy Support: Ondem 4 Tablet can help manage nausea and vomiting experienced by patients undergoing radiation therapy, improving treatment tolerance.
•Postoperative Nausea Relief: Many patients experience nausea after surgical procedures, and Ondem 4 Tablet is effective in controlling and reducing these symptoms.

Directions for Use

Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.

Medicinal Benefits

Ondem 4 Tablet belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Ondem 4 Tablet acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

How Ondem 4 Tablet Works

Ondem 4 Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondem 4 Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ondem 4 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Avoid rubbing or scratching the affected area, as this can cause further irritation and discomfort.
  • Consider using a humidifier to add moisture to the air and help reduce the sensation.
  • Seek medical attention if the sensation is severe, persistent, or worsens over time.
  • Avoid extreme temperatures, such as hot or cold showers, that can exacerbate the sensation.
  • Wear light, breathable clothing to help keep the body cool and reduce the sensation.
  • Avoid triggers that can cause the sensation, such as spicy foods or hot drinks.
  • Use cool compresses or fans to help lower body temperature and reduce the sensation.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Ondem 4 Tablet

Do not take more than the prescribed dose of Ondem 4 Tablet as it may cause overdose. The symptoms of overdose include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness or lightheadedness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Ondem 4 Tablet may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondem 4 Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondem 4 Tablet daily. Ondem 4 Tablet should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Ondem 4 Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronClomipramine
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Ondem 4 Tablet:
Taking Ondem 4 Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondem 4 Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronClomipramine
Severe
How does the drug interact with Ondem 4 Tablet:
The combined use of Ondem 4 Tablet with clomipramine can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking clomipramine and Ondem 4 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronAnagrelide
Severe
How does the drug interact with Ondem 4 Tablet:
Taking Ondem 4 Tablet with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem 4 Tablet alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronTranylcypromine
Severe
How does the drug interact with Ondem 4 Tablet:
When Ondem 4 Tablet, is taken with tranylcypromine it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
Although taking Ondem 4 Tablet along with tranylcypromine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronVilazodone
Severe
How does the drug interact with Ondem 4 Tablet:
When Vilazodone is taken with Ondem 4 Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Ondem 4 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
OndansetronDextromethorphan
Severe
How does the drug interact with Ondem 4 Tablet:
Co-administration of Ondem 4 Tablet and Dextromethorphan may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Ondem 4 Tablet and Dextromethorphan, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), extreme changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasms or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
OndansetronEscitalopram
Severe
How does the drug interact with Ondem 4 Tablet:
Taking Ondem 4 Tablet with escitalopram may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Co-administration of Ondem 4 Tablet along with escitalopram can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
OndansetronMethadone
Severe
How does the drug interact with Ondem 4 Tablet:
Taking Ondem 4 Tablet with methadone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem 4 Tablet along with methadone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronPentazocine
Severe
How does the drug interact with Ondem 4 Tablet:
Taking Pentazocine with Ondem 4 Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Taking Ondem 4 Tablet with Pentazocine together can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
OndansetronOsimertinib
Severe
How does the drug interact with Ondem 4 Tablet:
Taking Ondem 4 Tablet with Osimertinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem 4 Tablet along with Osimertinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 

  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.

  • Eat cool foods instead of hot and spicy foods.

  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

 

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Ondem 4 Tablet Substitute

Substitutes safety advice

  • Nuavomin 4 mg Tablet

    by Others

    ₹5.75per tablet

  • Ondem-MD 4 Tablet 10's

    by Others

    ₹5.18per tablet

  • Emeset-4 Tablet 10's

    by Others

    ₹5.18per tablet

  • Zofer MD 4 Tablet 10's

    by Others

    ₹5.13per tablet

  • Vomikind MD 4 Tablet 10's

    by Others

    ₹4.50per tablet

Product Substitutes

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Alcohol

Unsafe

One should avoid consuming alcohol while taking Ondem 4 Tablet as this medicine can interact with alcohol and may worsen the side effects.

bannner image

Pregnancy

Safe if prescribed

Ondem 4 Tablet could be used during pregnancy after consulting a doctor.

bannner image

Breast Feeding

Safe if prescribed

Ondem 4 Tablet could be used during breastfeeding after consulting a doctor.

bannner image

Driving

Caution

Ondem 4 Tablet may cause lightheadedness in the body, so a person taking Ondem 4 Tablet should avoid driving or operating any heavy machinery or tasks that require mental alertness.

bannner image

Liver

Safe if prescribed

In persons dealing with liver problems, the use of Ondem 4 Tablet is allowed if prescribed by the doctor. However, in patients with severe liver problems should take a low dose of Ondem 4 Tablet as much as possible. Do not take more than 8 mg of Ondem 4 Tablet per day in case of liver disease.

bannner image

Kidney

Safe if prescribed

The use of Ondem 4 Tablet is safe in patients dealing with kidney disorders. No dose adjustment is required.

bannner image

Children

Safe if prescribed

Ondem 4 Tablet should not be given to the children below 4 years of age. The use of Ondem 4 Tablet is safe in children above 4 years of age if prescribed by the doctor.

FAQs

Ondem 4 Tablet is indicated in the treatment of nausea and vomiting.

Ondem 4 Tablet works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

Ondem 4 Tablet may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.

People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondem 4 Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondem 4 Tablet daily. Taking Ondem 4 Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Ondem 4 Tablet is an anti-sickness medicine that takes about 1-2 hours to show its action.

Ondem 4 Tablet contains Ondansetron, an antiemetic drug.

Ondem 4 Tablet is ineffective in preventing nausea associated with motion sickness.

Before taking the Ondem 4 Tablet , let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Yes, Ondem 4 Tablet might make you feel sleepy or tired.

Ondem 4 Tablet usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.

Common side effects of Ondem 4 Tablet may include warmth, constipation, headache, diarrhoea, drowsiness, and tiredness. However, not every person faces these side effects, and even some of the unpleasant effects of Ondem 4 Tablet do not require medical attention.

Ondem 4 Tablet was not found to be beneficial in the treatment of seasickness.

Ondem 4 Tablet works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Ondem 4 Tablet prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Yes, you can take Ondem 4 Tablet half an hour to 1 hour before meals.

If you forget to take a dose of Ondem 4 Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

Ondem 4 Tablet may cause changes in the vision, so one should avoid driving or operating any machine that requires mental alertness.

Suppose you took more than the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Ondem 4 Tablet may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

No, Ondem 4 Tablet is not a steroid. Ondem 4 Tablet belongs to a class of drugs known as anti-emetics.

While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.

Take Ondem 4 Tablet exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.

Yes, Ondem 4 Tablet has also been prescribed during pregnancy to help with symptoms of nausea and vomiting in pregnancy.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OND0001

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Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 15, 2025 | 2:39 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020103s035_020605s019_020781s019lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.6049.pdf
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