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compositionComposition:FLUCONAZOLE-50MG
prescription
Prescription Medicine
info
Onecan 50 Tablet 4's

Onecan 50 Tablet is used to treat a broad range of infections caused due to fungi and yeast. It contains Fluconazole, which kills or prevents the growth of fungi or yeast. It may cause common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUCONAZOLE-50MG

Manufacturer/Marketer :

Wallace Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Onecan 50 Tablet

Onecan 50 Tablet is a prescription medication used to treat a wide variety of fungal infections. It works by stopping the growth of certain types of yeast and fungi that cause discomfort and illness in the body. Doctors commonly prescribe this medicine to treat fungal infections in the mouth, throat, oesophagus, and vaginal area.

To get the best results, you should take Onecan 50 Tablet consistently and exactly as your doctor prescribes, even if your symptoms clear up after only a few doses. You can take this oral medicine with or without food. Making simple lifestyle adjustments, such as maintaining good hygiene and avoiding excess moisture in affected areas, can also help support your recovery.

While taking this medication, you may experience mild side effects like an upset stomach, headache, or mild diarrhoea. However, you should consult your doctor immediately if you experience serious side effects, such as signs of liver damage or a severe skin rash. Your healthcare provider can help determine if these symptoms require medical attention.

Talk to your doctor before starting this medicine if you have a history of liver disease, kidney disease, or heart rhythm disorders. Do not take this if you are allergic to similar antifungal medicines or if you take other medications that can affect your heart rhythm. Your doctor will help evaluate if this treatment is safe for your specific health profile.

This medicine can interact with blood thinners, certain diabetes medications, and alcohol, which can increase the risk of side effects or affect how the drug works. Pregnant or breastfeeding women, as well as elderly individuals, must consult their healthcare provider before using this medicine, as special dosing or alternative treatments may be necessary.

Uses of Onecan 50 Tablet

Onecan 50 Tablet is used to treat infections. The detailed uses of Onecan 50 Tablet are as follows:

  • Vaginal yeast infections: Onecan 50 Tablet helps clear up vaginal itching, burning, and unusual discharge by stopping the overgrowth of vaginal yeast.
  • Oral thrush: Onecan 50 Tablet treats painful white patches in the mouth and throat by reducing fungal levels in the oral cavity.
  • Oesophageal candidiasis: Onecan 50 Tablet helps relieve painful or difficult swallowing caused by fungal infections in the food pipe.
  • Systemic fungal infections: Onecan 50 Tablet treats serious, deep-seated fungal infections in the bloodstream or internal organs by halting the spread of the fungus.

Key Benefits

Onecan 50 Tablet helps treat fungal infections by reducing fungal growth and improving infection-related symptoms. This medicine brings several key health benefits:

  • Convenient oral administration: Because this medication is taken by mouth, it provides an easy and mess-free alternative to localised topical creams or vaginal inserts.
  • Effective prevention: For individuals with weakened immune systems, this medicine helps prevent recurring or severe fungal infections before they can start, offering peace of mind.
  • Relief from uncomfortable symptoms: This medicine treats the underlying fungal infection, which can help improve symptoms such as itching, burning, and pain as the infection starts to clear. The time needed for improvement depends on the type and severity of the infection.
Side effects of Onecan 50 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.

Directions for Use

To ensure the medication works safely and effectively, please follow these step-by-step instructions:

  • Swallow the tablet or capsule whole with a full glass of water. Do not crush, chew, or break it.
  • You may take this medicine with or without food, as food does not affect how it is absorbed.
  • If you are taking the liquid suspension form, shake the bottle thoroughly before each use and measure your dose carefully using the provided medical syringe or spoon.
  • Take your dose at the same time each day to maintain a steady level of the medicine in your body.

Always follow your doctor's exact instructions regarding your dose and how long you should continue taking this medicine, even if you start to feel better early in the treatment course.

How Onecan 50 Tablet Works

Onecan 50 Tablet contains fluconazole. It works by blocking an important process that fungi need to build their protective outer layer. It stops the production of a substance called ergosterol, which helps maintain the structure and strength of fungal cells. By reducing ergosterol production, this medicine weakens the fungal cell membrane and stops the fungus from growing and spreading, allowing your body to fight the infection.
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Alcohol

Unsafe

It is advisable to avoid or limit the intake of alcohol while you use Onecan 50 Tablet.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant or are planning to conceive before starting Onecan 50 Tablet.

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Breast Feeding

Caution

Onecan 50 Tablet should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.

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Driving

Caution

Onecan 50 Tablet may sometimes cause dizziness or other side effects that may affect your mental ability to drive. Hence do not drive or operate machinery if you are not mentally alert.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases when you are prescribed Onecan 50 Tablet.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases when you are prescribed Onecan 50 Tablet.

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Children

Caution

Onecan 50 Tablet may be prescribed to children by the doctor, depending on the infection. The doctor decides the right dose for a child based on his/her age and weight.

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Heart

Unsafe

Onecan 50 Tablet is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Consult your doctor

Limited information is available. Please consult your doctor.

What if I have taken an overdose of Onecan 50 Tablet

Do not take more than the prescribed dose of Onecan 50 Tablet as it may cause serious side effects. The symptoms of overdose include mental/mood changes and hallucinations. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Reduce sugar intake: Yeast thrives on sugar. Limiting sweet foods, sugary drinks, and refined carbohydrates can help starve the fungus and speed up your recovery.
  • Stay hydrated: Drink plenty of water to help your kidneys efficiently process and flush the medication from your body.
  • Wear breathable fabrics: If you are treating a vaginal yeast infection, wear loose cotton underwear and avoid tight synthetic pants to prevent moisture buildup where yeast grows.
  • Avoid douching: Do not use scented body washes, douches, or feminine sprays, as these can disrupt the natural balance of bacteria and worsen yeast infections.
  • Support your gut: Consider eating unsweetened yogurt with active cultures to help rebuild healthy bacteria levels that keep yeast in check.

Have a query?

How Soon It Starts Working

The time required for Onecan 50 Tablet to start to work: The time required for Onecan 50 Tablet to show its action is unknown.

The time for which the effects of Onecan 50 Tablet last: The duration of action for Onecan 50 Tablet is unknown.

What if you forget to take Onecan 50 Tablet

If you miss a dose of Onecan 50 Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Onecan 50 Tablet tablets or capsules at room temperature, ideally in the range 20°C to 25°C (68°F to 77°F). •Keep all forms of this medication safely out of reach of children and pets.

Drug Warnings

  • Complete the full course: Always finish the entire prescription even if you feel completely better, as stopping early can cause the infection to return.
  • Monitor your skin: Check your skin regularly for any new rashes, as this medication can occasionally trigger severe skin reactions.
  • Report unusual fatigue: Keep an eye out for extreme tiredness, loss of appetite, or stomach pain, which can be early warning signs of liver strain.
  • Avoid driving if dizzy: This medicine can sometimes cause dizziness; do not drive or operate machinery until you know how it affects you.
  • Check liquid suspension: If using the liquid form, ensure it is thoroughly mixed and has a uniform color before taking your dose.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Blood thinners (like warfarin): May increase your risk of bleeding, requiring regular blood monitoring.
  • Diabetes medications (like glipizide): May increase the risk of low blood sugar, so you should monitor your glucose levels closely.
  • Heart rhythm medications: Combining these can cause dangerous, irregular heartbeats.
  • Seizure medicines (like phenytoin): May raise the levels of the seizure medication in your body, increasing the risk of side effects.

 

Drug-Food Interactions:

  • Alcohol: Drinking alcohol while taking this medicine can increase the risk of liver damage and worsen dizziness.

 

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking this medicine as it may worsen your condition or cause complications.

  • Liver disease: May worsen liver function, requiring close monitoring or a different treatment option.
  • Kidney disease: The body may clear the drug more slowly, which might require your doctor to adjust your dose.
  • Heart conditions (like QT prolongation): Can increase the risk of serious, irregular heart rhythms.
FluconazoleEliglustat
Critical
FluconazoleErythromycin
Critical

Drug-Drug Interactions

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FluconazoleEliglustat
Critical
How does the drug interact with Onecan 50 Tablet:
When Eliglustat and Onecan 50 Tablet are taken together, Onecan 50 Tablet can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Onecan 50 Tablet with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with Onecan 50 Tablet:
Taking Onecan 50 Tablet with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Onecan 50 Tablet with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with Onecan 50 Tablet:
When Lomitapide is taken with Onecan 50 Tablet, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Onecan 50 Tablet with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Onecan 50 Tablet:
When Astemizole is taken with Onecan 50 Tablet, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Onecan 50 Tablet with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleAmisulpride
Severe
How does the drug interact with Onecan 50 Tablet:
Taking Amisulpride with Onecan 50 Tablet may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Amisulpride can be taken with Onecan 50 Tablet if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not discontinue any medications without consulting a doctor.
FluconazoleWarfarin
Severe
How does the drug interact with Onecan 50 Tablet:
Co-administration of Warfarin with Onecan 50 Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking Onecan 50 Tablet and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
FluconazoleAlfentanil
Severe
How does the drug interact with Onecan 50 Tablet:
Co-administration of Alfentanil and Onecan 50 Tablet may significantly increase the blood levels of ALfentanil which may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Alfentanil and Onecan 50 Tablet, you can take these medicines together if prescribed by a doctor. These symptoms include feeling very tired, having trouble breathing, feeling dizzy or lightheaded, having low blood pressure, having an irregular heartbeat, or having any other problems. Do not stop using any medications without a doctor's advice.
FluconazoleMoxifloxacin
Severe
How does the drug interact with Onecan 50 Tablet:
Taking Onecan 50 Tablet with Moxifloxacin can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Onecan 50 Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience dizziness, shortness of breath, or irregular heartbeat consult a doctor. Do not discontinue the medications without consulting a doctor.
FluconazoleVemurafenib
Severe
How does the drug interact with Onecan 50 Tablet:
Taking Onecan 50 Tablet with vemurafenib may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Onecan 50 Tablet can be taken with vemurafenib if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without a doctor's advice.
FluconazoleRibociclib
Severe
How does the drug interact with Onecan 50 Tablet:
Taking Onecan 50 Tablet with Ribociclib may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Onecan 50 Tablet can be taken with Ribociclib if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Onecan 50 Tablet is used in the treatment of fungal infections.
Onecan 50 Tablet contains Fluconazole, an antifungal drug, which works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.
Do not stop using Onecan 50 Tablet even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.
The usual recommendation of dosage for Onecan 50 Tablet can be for a short time. However, your doctor may prescribe it for a longer time, depending on the type and severity of your infection.
Onecan 50 Tablet may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. However, it is advised to seek a doctor's advice before starting Onecan 50 Tablet if you have a previous medical history.
Onecan 50 Tablet is a prescription antifungal medication used to treat various fungal infections. Before taking Onecan 50 Tablet, you must consult a doctor to ensure it's the right medication for your condition and discuss any potential risks or interactions.
No, Onecan 50 Tablet is not typically used to treat cough, cold, or flu. It's an antifungal medication designed to treat fungal infections, not viral infections like the common cold or flu.
It's always best to follow your doctor's specific instructions regarding when to take Fluconazole. They can provide personalized advice based on your individual needs and medical history.
Onecan 50 Tablet has common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
Onecan 50 Tablet can interact with other drugs. Inform your healthcare practitioner of all medications you are taking, including over-the-counter medicines, prescription medications, and herbal supplements.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.
No, do not use Onecan 50 Tablet after the expiration date, as they may no longer be effective.
Dispose of unused medicines according to your local pharmacy's guidelines. Do not flush them down the toilet or pour them down the drain.
Most people begin to feel relief from their symptoms within 1 to 3 days after taking the medicine. However, it may take several days for the infection to clear up completely. Talk to your doctor if your symptoms do not improve after a few days.
Taking this medicine during pregnancy is generally not recommended, especially in high doses or for long periods, as it may harm the unborn baby. If you are pregnant or planning to become pregnant, talk to your doctor to discuss safer treatment options.
It is best to avoid alcohol while taking this medication. Alcohol can increase your risk of liver strain and make side effects like dizziness or an upset stomach worse. Talk to your doctor about what is safe for you.
If your symptoms return or do not clear up completely, do not take another dose on your own. Recurring infections may require a different dosing schedule or a different medication entirely. Talk to your doctor for an accurate diagnosis and treatment plan.
No, this medication should not make your infection worse. If your itching, burning, or discomfort increases significantly after taking it, you might be experiencing an allergic reaction or a different type of infection. Talk to your doctor immediately.
Onecan 50 Tablet does not usually reduce the effectiveness of birth control pills. However, it may affect how your body processes certain hormones in some cases. If you use oral contraceptives or have concerns about interactions, talk to your doctor or pharmacist for personalised advice.
Yes, this medicine can be prescribed to children and even infants for certain fungal infections. The child's dose will be carefully calculated by a healthcare provider based on their weight and the type of infection. Talk to your doctor to determine the appropriate use.

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Reference

  1. National Center for Biotechnology Information (NCBI). Nbk537158 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  2. National Center for Biotechnology Information (NCBI). Fluconazole Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Fluconazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. National Health Service (NHS). Fluconazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  5. Fluconazole Fluconazole. 2014. [Accessed on 29 Mar. 2019] Check here
  6. Diflucan 150 Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 17 November 2021] Check here
  7. DIFLUCAN Tablets/Oral Suspension USP [Internet]. Accessdata.fda.gov. 2021 [Accessed on 17 November 2021]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
Other Info - ONE0002

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