Onivyde 43 mg/10Ml Injection 1's

₹97116

(Inclusive of all Taxes)

₹14567.4 Cashback (15%)

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Onivyde 43 mg/10Ml Injection 1's is used to manage or treat Colorectal cancer (Cancer that develops in the colon or rectal tissue). It contains Irinotecan, which works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells cannot divide. As a result, Irinotecan inhibits cancer cell division and growth.

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About Onivyde 43 mg/10Ml Injection 1's

Onivyde 43 mg/10Ml Injection 1's belongs to a class of antineoplastic medications or chemotherapy drugs primarily used to manage or treat Colorectal cancer (Cancer that develops in the colon or rectal tissue). Colorectal cancer is a disease in which cells in the colon or rectum grow out of control.

Onivyde 43 mg/10Ml Injection 1's contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can not divide. As a result, Irinotecan inhibits cancer cell division and growth.

Onivyde 43 mg/10Ml Injection 1's should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. The most common adverse reactions are nausea, vomiting, abdominal pain, diarrhoea, constipation, anorexia (an eating disorder), Neutropenia (an unusually low number of cells called neutrophils), leukopenia (including lymphocytopenia), anaemia (not having enough healthy red blood cells), asthenia (abnormal weakness), fever, weight loss, alopecia (hair loss). You should talk to your doctor if you persistently experience these side effects.

Avoid using Onivyde 43 mg/10Ml Injection 1's if you are allergic to it. Onivyde 43 mg/10Ml Injection 1's can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on treatment with Onivyde 43 mg/10Ml Injection 1's. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Onivyde 43 mg/10Ml Injection 1's

Onivyde 43 mg/10Ml Injection 1's is used to treat cancers of the colon and rectum. The detailed uses of Onivyde 43 mg/10Ml Injection 1's are as follows:<br/>• Treats colon and rectal cancer: Onivyde 43 mg/10Ml Injection 1's is used alone or with other medications to manage cancer that starts in the large intestine.<br/>• Used in combination regimens: Onivyde 43 mg/10Ml Injection 1's is often given with other anticancer drugs to enhance effectiveness in advanced or metastatic colorectal cancer.<br/>• Stops cancer cell growth: Onivyde 43 mg/10Ml Injection 1's works by inhibiting topoisomerase I, an enzyme necessary for cancer cell replication, thereby slowing or preventing tumor growth.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Onivyde 43 mg/10Ml Injection 1's will be administered by a trained healthcare professional.• Do not self-administer.

Medicinal Benefits

Onivyde 43 mg/10Ml Injection 1's is an antineoplastic medicine or chemotherapeutic treatment used to control or treat colorectal cancer (colon or rectal cancer). Onivyde 43 mg/10Ml Injection 1's contains Irinotecan acts by inhibiting an enzyme known as topoisomerase I. This enzyme is required for all cells to divide and flourish. Irinotecan inhibits this enzyme, preventing cancer cells from dividing. As a result, Irinotecan inhibits cancer cell division and growth.

How Onivyde 43 mg/10Ml Injection 1's Works

Onivyde 43 mg/10Ml Injection 1's contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can not divide. As a result, Irinotecan inhibits cancer cell division and growth.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Onivyde 43 mg/10Ml Injection 1's out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ÂºC to 25ÂºC or below 30ÂºC.

What if I have taken an overdose of Onivyde 43 mg/10Ml Injection 1's

Since Onivyde 43 mg/10Ml Injection 1's is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Onivyde 43 mg/10Ml Injection 1's may cause severe neutropenia and severe diarrhoea.

Drug Warnings

Before taking the Onivyde 43 mg/10Ml Injection 1's, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may also suffer severe diarrhoea (known as ''late diarrhoea'') more than 24 hours after receiving Irinotecan. Your doctor would advise you to take antidiarrheal drugs at regular intervals throughout the day and night. When taking antidiarrheal drugs, always follow your doctor's instructions. During your therapy, your doctor will also inform you which foods to take and which to avoid to reduce diarrhoea. Drink plenty of fluids and strictly adhere to this diet.

Diet & Lifestyle Advise

After your treatment begins, several dietary adjustments can help you control side effects.
Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
Eat a healthy diet and exercise regularly to maintain proper weight.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Performing yoga may also help in improving both physical and mental health.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get optimal sleep; rest well.
Avoid smoking and alcohol consumption.
Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Alcohol

Caution

Avoid alcohol consumption while on treatment with Onivyde 43 mg/10Ml Injection 1's.

Pregnancy

Unsafe

Onivyde 43 mg/10Ml Injection 1's should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

Breast Feeding

Unsafe

Onivyde 43 mg/10Ml Injection 1's should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

Driving

Caution

Onivyde 43 mg/10Ml Injection 1's can make you dizzy or impair your vision, especially in the first 24 hours after taking it. Do not drive or operate machinery until you know how this drug affects you.

Liver

Caution

Onivyde 43 mg/10Ml Injection 1's should be used with caution if you have liver disease. Inform your doctor before receiving the Onivyde 43 mg/10Ml Injection 1's if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

Kidney

Caution

It is not recommended for use in patients on dialysis. Inform your doctor before receiving the Onivyde 43 mg/10Ml Injection 1's if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

Children

Caution

Safety and effectiveness in children have not been established. Hence, use is not recommended.

Have a query?

FAQs

What is the use of Onivyde 43 mg/10Ml Injection 1's?

Onivyde 43 mg/10Ml Injection 1's is used to treat Colorectal cancer.

How does Onivyde 43 mg/10Ml Injection 1's work?

Onivyde 43 mg/10Ml Injection 1's contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can&#039;t divide. As a result, Irinotecan inhibits cancer cell division and growth.

Is it ideal to use Onivyde 43 mg/10Ml Injection 1's in patients with pulmonary disorders?

Onivyde 43 mg/10Ml Injection 1's should not be used in patients with pulmonary diseases. So, inform your doctor if you have pulmonary disorders (lung problems).

What important things should I take care of while taking Onivyde 43 mg/10Ml Injection 1's?

While taking Onivyde 43 mg/10Ml Injection 1's, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Onivyde 43 mg/10Ml Injection 1's.

Can I have vaccinations while on this therapy?

The live vaccine may not work while on treatment with Onivyde 43 mg/10Ml Injection 1's. Only have immunizations/vaccinations after talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Does Onivyde 43 mg/10Ml Injection 1's therapy cause Neutropenia?

Irinotecan therapy may lead to Neutropenia (an unusually low number of neutrophil cells). Your doctor will order laboratory testing on a regular basis before and during your treatment.

Is Onivyde 43 mg/10Ml Injection 1's a cause of infertility?

You should know that this medicine may reduce fertility in both men and women. Discuss the risks of taking an irinotecan injection with your doctor.

Can Onivyde 43 mg/10Ml Injection 1's be used in pregnancy?

You are recommended to take the advice of your doctor before taking Onivyde 43 mg/10Ml Injection 1's. As Onivyde 43 mg/10Ml Injection 1's is not used during pregnancy.

What are the side effects of Onivyde 43 mg/10Ml Injection 1's?

The common side effects of Onivyde 43 mg/10Ml Injection 1's are nausea, vomiting, abdominal pain, diarrhoea, constipation, anorexia (an eating disorder), neutropenia (an unusually low number of cells called neutrophils), leukopenia (including lymphocytopenia), anaemia (not having enough healthy red blood cells), asthenia (abnormal weakness), fever, weight loss, alopecia (hair loss). If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Floor No. 1703, Plot No. C38 & 39, 17th Floor, Parinee Crescenzo, Kautilya Bhawan-2, B Wing, behind MCA, G Block BKC, Bandra Kurla Complex, Bandra East, Mumbai, Maharashtra 400051

Other Info - ONI0061

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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FAQs

What is the use of Onivyde 43 mg/10Ml Injection 1's?

How does Onivyde 43 mg/10Ml Injection 1's work?

Is it ideal to use Onivyde 43 mg/10Ml Injection 1's in patients with pulmonary disorders?

What important things should I take care of while taking Onivyde 43 mg/10Ml Injection 1's?

Can I have vaccinations while on this therapy?

Does Onivyde 43 mg/10Ml Injection 1's therapy cause Neutropenia?

Is Onivyde 43 mg/10Ml Injection 1's a cause of infertility?

Can Onivyde 43 mg/10Ml Injection 1's be used in pregnancy?

What are the side effects of Onivyde 43 mg/10Ml Injection 1's?

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