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Opdyta 100 mg Injection 10 ml used to treat various cancers, including Metastatic Melanoma, metastatic non-small cell lung cancer, Renal Cell Carcinoma, Hepatocellular carcinoma, Colorectal Cancer, Malignant pleural mesothelioma, Stomach Cancer, Squamous cell carcinoma of head and neck, and Urothelia carcinoma. It contains Nivolumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the action of a programmed death receptor-1 (PD-1), thereby stopping the abnormal growth of cancer cells.
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About Opdyta 100 mg Injection 10 ml
Opdyta 100 mg Injection 10 ml is an anti-cancer medicine used in the treatment of Melanoma in combination with ipilimumab and other cancers in adults. Melanoma is a severe form of skin cancer that spreads primary melanoma cells to distant organs such as lymph nodes, lungs, liver, brain, and bones. This medicine is used in treating advanced renal cell carcinoma, hepatocellular carcinoma, colorectal cancer, metastatic non-small cell lung cancer, metastatic melanoma, gastric cancer, classical Hodgkin’s disease, urothelial carcinoma, malignant pleural mesothelioma and head and neck cancer.
Opdyta 100 mg Injection 10 ml contains Nivolumab, which belongs to the class of monoclonal antibody. It works by inhibiting the action of a programmed death receptor-1 (PD-1), thereby stopping the abnormal growth of cancer cells.
Opdyta 100 mg Injection 10 ml may cause certain side effects such as diarrhoea, nausea, vomiting, tiredness, itching, rash, headache, fever, shortness of breath, muscle/joint pain, loss of appetite and injection site reactions. Inform your doctor if any of these side effects persist for longer. Opdyta 100 mg Injection 10 ml will be administered by an oncologist trained in administering anti-cancer agents.
Avoid receiving Opdyta 100 mg Injection 10 ml and inform your doctor if you are allergic to it or any other components of it. Before taking Opdyta 100 mg Injection 10 ml, tell your doctor if you have/had liver or kidney disease, autoimmune disorders such as ulcerative colitis or Crohn's disease, a history of organ transplants, received an allogeneic stem cell transplant, or had radiation treatment to the chest. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy. Avoid breastfeeding while taking this Opdyta 100 mg Injection 10 ml.
Uses of Opdyta 100 mg Injection 10 ml
Opdyta 100 mg Injection 10 ml is used in the treatment of cancer. The detailed use of Opdyta 100 mg Injection 10 ml is as follows:

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Directions for Use
Medicinal Benefits
Opdyta 100 mg Injection 10 ml contains Nivolumab, which is used in the treatment of different types of cancers. It works by inhibiting the action of a programmed death receptor-1 (PD-1) that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other body parts.
How Opdyta 100 mg Injection 10 ml Works
Storage
What if I have taken an overdose of Opdyta 100 mg Injection 10 ml
Drug Warnings
To treat your condition effectually, continue receiving Opdyta 100 mg Injection 10 ml for the period that your doctor has prescribed. Opdyta 100 mg Injection 10 ml may cause severe immune-mediated adverse reactions (IMAR) such as immune-mediated colitis, hepatitis, hepatotoxicity, nephritis, endocrinopathies, pneumonitis, complications of allogeneic Hematopoietic Stem Cell Transplantation (allo HSCT) and dermatologic reactions. It may also cause infusion-related reactions in some patients. Therefore, caution should be exercised if you have/had liver or kidney disease, any history of organ transplant, gastrointestinal disorders, myasthenia gravis, received a stem cell transplant that uses donor stem cells (allogeneic), undergone radiation treatment to the chest and autoimmune disorders such as ulcerative colitis, or Crohn’s disease while receiving Opdyta 100 mg Injection 10 ml. Discontinue the treatment if any severe infusion reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy are not established.
Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Consult your doctor
It is unknown whether Opdyta 100 mg Injection 10 ml interacts with alcohol. Consult your doctor for more information.
Pregnancy
Unsafe
Opdyta 100 mg Injection 10 ml is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Opdyta 100 mg Injection 10 ml. You should not become pregnant while you are receiving Opdyta 100 mg Injection 10 ml for at least five months from the last dose of Opdyta 100 mg Injection 10 ml. Using effective birth control methods while on treatment is suggested.
Breast Feeding
Unsafe
Opdyta 100 mg Injection 10 ml should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine and for at least five months from the last dose of medicine.
Driving
Not applicable
Opdyta 100 mg Injection 10 ml will be administered to hospitalized patients.
Liver
Caution
If you have a pre-existing or a history of liver problems, tell your doctor before receiving this medicine. Inform your doctor if you experience severe nausea or vomiting, right-sided upper stomach pain, easy bruising or bleeding, dark urine, or jaundice (yellowing of the skin or eyes). Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.
Kidney
Caution
If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Opdyta 100 mg Injection 10 ml. Tell your doctor if you have little or no urination, swelling in your feet or ankles, or blood in your urine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Safe if prescribed
Opdyta 100 mg Injection 10 ml is not recommended for children below 12 years. It is safe for use in children above 12 years for the treatment of microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer. It will be administered only if the benefits outweigh the risks.
Heart
Please consult your doctor before receiving Opdyta 100 mg Injection 10 ml if you have pre-existing heart problems. Your doctor will prescribe Opdyta 100 mg Injection 10 ml if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Please consult a doctor before administering Opdyta 100 mg Injection 10 ml to geriatric patients. Your doctor will prescribe Opdyta 100 mg Injection 10 ml if the benefits outweigh the risks.
Opdyta 100 mg Injection 10 ml is used to treat various cancers, including Metastatic Melanoma, metastatic non-small cell lung cancer, Renal Cell Carcinoma, Hepatocellular carcinoma, Colorectal Cancer, Malignant pleural mesothelioma, Stomach Cancer, Squamous cell carcinoma of head and neck, and Urothelia carcinoma.
Opdyta 100 mg Injection 10 ml contains Nivolumab, which works by inhibiting the action of a programmed death receptor-1 (PD-1) that causes the multiplication of cancerous cells.
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Keep Refrigerated. Do not freeze.
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