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  3. Osteofos 35 Tablet 4's

Osteofos 35 Tablet 4's, Pack of 4 TABLETS
Osteofos 35 Tablet 4's, Pack of 4 TABLETS
Osteofos 35 Tablet 4's, Pack of 4 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Osteofos 35 Tablet is used in the prevention and treatment of osteoporosis and Paget’s disease of the bone. This medicine promotes bone integrity by regulating bone cell turnover and preventing bone cell destruction by suppressing the activity of osteoclasts. Common side effects include muscle or joint pain, nausea, indigestion, gas and headache.

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Composition :

ALENDRONIC ACID-35MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Osteofos 35 Tablet

Osteofos 35 Tablet belongs to the group of fortified bisphosphonates used in the prevention and treatment of osteoporosis and Paget’s disease of the bone. Osteoporosis is a condition in which bones become weak and brittle. Paget’s disease of the bone is a disorder in which the replacement of old bone cells by new bone cells is disrupted and dysregulated. 

Osteofos 35 Tablet contains Alendronic acid, which promotes bone integrity by regulating bone cell turnover and preventing bone cell destruction by suppressing the activity of osteoclasts. Osteofos 35 Tablet strengthens bones, thereby reducing the risk of fractures.

Take Osteofos 35 Tablet as prescribed. In some cases, Osteofos 35 Tablet may cause side effects such as muscle or joint pain, nausea, indigestion, gas and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Keep your doctor informed if you suffer from any oesophageal disorders, jaw problems, peptic ulcer disease, kidney disease, low blood calcium, low Vitamin D, if you are a smoker or have had a history of smoking, or if you have been immobilised for some time and are unable to sit upright. Consult your doctor if you are pregnant or breastfeeding. 

Uses of Osteofos 35 Tablet

Osteofos 35 Tablet is used to treat Osteoporosis and Paget's disease of the bone. The detailed uses of Osteofos 35 Tablet are as follows:<br/>• Osteoporosis Treatment: Osteofos 35 Tablet helps strengthen bones and reduce the risk of fractures and it is prescribed for postmenopausal women and older men at risk of osteoporosis.<br/>• Paget’s Disease of Bone: Osteofos 35 Tablet is used to manage Paget’s disease and helps control excessive bone resorption and formation.<br/>• Prevention of Bone Loss Due to Steroid Use: Osteofos 35 Tablet is used in patients taking long-term corticosteroids, which can lead to decreased bone density.<br/>

Directions for Use

• Take it on an empty stomach, preferably 30 minutes before food or beverages, for better absorption. • Follow your doctor's instructions regarding dosage and timing for optimal results. • Swallow Osteofos 35 Tablet as a whole with a glass of water. • Do not crush, chew, or break it. Take it while sitting upright or standing. Try staying upright, and do not lie down for 30 minutes after taking it. Do not take Osteofos 35 Tablet at bedtime or just before waking up.

Medicinal Benefits

Osteofos 35 Tablet contains Alendronic acid, a bisphosphonate used to treat osteoporosis. It is used primarily to strengthen bones, joints, muscles and in the treatment of bone disease. Osteofos 35 Tablet works by preventing bone destruction and resorption, thereby retaining the normal density of bones. It slows down the activity of bone-destroying cells (osteoclasts), which tend to be in overdrive in case of bone diseases such as osteoporosis and Paget’s. Hence, Osteofos 35 Tablet is useful in strengthening and restoring the integrity and health of weak bones.

How Osteofos 35 Tablet Works

Osteofos 35 Tablet contains Alendronic acid, which promotes bone integrity by regulating bone cell turnover and preventing bone cell destruction by suppressing the activity of osteoclasts. Osteofos 35 Tablet strengthens bones, thereby reducing the risk of fractures.

Storage

Store at room temperature in a cool, dry place.
Side effects of Osteofos 35 Tablet
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Osteofos 35 Tablet

Never take more than the prescribed dose. Climatic skin, CNS depression, dysphagia, hiccups, miosis, respiratory depression, seizures, and wheezing are indications and symptoms of an overdose of Osteofos 35 Tablet. For the treatment of voluntary overdose, supportive therapy and monitoring of urine flow, calcium levels, and phsophorous level are crucial.

Drug Warnings

Avoid taking Osteofos 35 Tablet if you are allergic to any of its components. Inform your doctor if you suffer from any oesophageal disorders, jaw problems, peptic ulcer disease, kidney disease, low blood calcium, low Vitamin D, digestive problems, hyperparathyroidism, cancer, mouth infection, are on chemotherapy or radiotherapy, if you smoke, or if you have been immobilised for some time and are unable to sit upright. Keep your doctor informed if you have recently had any surgery or are about to undergo surgery or a dental procedure. Offer a detailed medical history and inform the doctor, especially if you are on steroids, antacids, antibiotics like gentamycin or amikacin, calcium supplements, laxatives containing magnesium, aspirin or any painkillers. Consult your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Alendronic acidEtelcalcetide
Severe
Alendronic acidNaproxen
Severe

Drug-Drug Interactions

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Alendronic acidEtelcalcetide
Severe
How does the drug interact with Osteofos 35 Tablet:
Co-administration of Osteofos 35 Tablet and Etelcalcetide may increase the risk of hypocalcemia (low levels of calcium).

How to manage the interaction:
Although taking Osteofos 35 Tablet and Etelcalcetide together can evidently cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your calcium levels. Make sure to regularly check a blood calcium level and let a doctor know if you experience any symptoms like numbness, muscle spasms, or irregular heartbeat. They can help you if anything feels off. Do not stop using any medications without talking to a doctor.
Alendronic acidNaproxen
Severe
How does the drug interact with Osteofos 35 Tablet:
Co-administration of Naproxen with Osteofos 35 Tablet may increase the risk or severity of side effects.

How to manage the interaction:
Taking Naproxen with Osteofos 35 Tablet together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you develop severe stomach pain, bloating, sudden dizziness, lightheadedness, vomiting (especially with blood), nausea, loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Alendronic acidDeferasirox
Severe
How does the drug interact with Osteofos 35 Tablet:
Co-administration of Osteofos 35 Tablet (oral form) with Deferasirox may increase the risk of developing gastrointestinal ulcers.

How to manage the interaction:
Although there is a possible interaction between Osteofos 35 Tablet and Deferasirox, you can take these medicines together if advised by your doctor. However, if you develop severe stomach pain, bloating, sudden dizziness or lightheadedness, vomiting (especially with blood), nausea, loss of appetite, and/or black, tarry stools, contact your doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Load up on Vitamin D rich foods such as oily fish, egg yolks, spinach, broccoli, salmon and orange juice to promote bone health.
  • Stay hydrated by drinking plenty of water.
  • Doing weight-bearing exercises such as brisk walking, jogging, tennis, or even dance can be very useful in promoting overall bone health. However, do not over-exert yourself if you feel too tired or suffer from severely brittle bones. 
  • Muscle training activities such as yoga and Pilates can also be very helpful.
  • Spend time under the sun (however, with proper sunscreen) for quality intake of Vitamin D.
  • Limit alcohol and caffeine consumption and stop smoking as these may have a negative effect on bone health. Smokers tend to have lower bone density than non-smokers. 

Habit Forming

No

Therapeutic Class

BONE ENHANCERS

Osteofos 35 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consuming alcohol with Osteofos 35 Tablet as it may cause increased dizziness. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Osteofos 35 Tablet is not indicated in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Osteofos 35 Tablet is not indicated in breastfeeding women. Please consult your doctor if you have any concerns.

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Driving

Caution

Osteofos 35 Tablet usually does not affect your ability to drive. However, in rare cases, it may cause dizziness, muscle or bone pain. So, drive only if you are alert.

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Liver

Caution

Exercise caution before using Osteofos 35 Tablet in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Osteofos 35 Tablet in case of established kidney disease. Please consult your doctor to address any concerns. Osteofos 35 Tablet is not recommended for patients with renal impairment.

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Children

Unsafe

Osteofos 35 Tablet is not recommended for use in children below. Please consult your doctor if you have any concerns.

Have a query?

FAQs

Osteofos 35 Tablet is used in the prevention and treatment of osteoporosis and Paget’s disease of the bone.

Osteofos 35 Tablet works by maintaining bone density. It helps in supporting bones and joints by inhibiting bone-destroying cells from being overactive.

Please see an orthopaedic doctor if you have had a fracture. Osteofos 35 Tablet is used in the case of osteoporosis and has limited use in the direct treatment of fractures as a fracture is more of surgical concern.

It usually takes one month for Osteofos 35 Tablet to start working. However, full benefits may take six months to one year to show.

Osteofos 35 Tablet can be taken with other medicines if prescribed by the doctor. However, maintaining a gap of 30minutes between Osteofos 35 Tablet and other medicines is advised.

Consult your doctor before taking NSAID&amp;#039;s/pain killer medicines along with Osteofos 35 Tablet.

Osteofos 35 Tablet may cause osteonecrosis of the jaw. It is a bone disease in which there is a loss of blood to the bone. Maintain good oral hygiene, and have a regular dental check-up throughout the treatment with Osteofos 35 Tablet. Consult your dentist if you experience any problems such as loose teeth, swelling, or pain.

You can help keep your bones healthy by making some fundamental lifestyle changes, including eating food for strong bones (foods high in calcium and vitamin D), Getting vitamin D from sunlight, Exercising (walking and low-impact aerobics are suitable for your bones), Stopping smoking, and Cutting down on alcohol.

You'll usually take Osteofos 35 Tablet long term. Your doctor will then review your ongoing need for it. Your doctor will usually assess your risk of broken bones every 3 to 5 years. This may include tests to check your bones' strength (density). Depending on the results, you'll either keep taking Osteofos 35 Tablet, take a break from it or stop taking it completely.

The best time to take your medicine is usually 30 minutes before you have breakfast. Take it on an empty stomach. Osteofos 35 Tablet works best on an empty stomach because your body can absorb it properly.

Swallow it as a whole with water; do not crush, break or chew it. It's important to follow the instructions for this medicine very carefully.

Osteofos 35 Tablet may cause has a side effect of causing hair loss. Consult your doctor if it persists.

Osteofos 35 Tablet is not indicated in pregnancy. Please consult your doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - OST0003

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:56 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5697.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021575s017lbl.pdf
  3. https://www.nhs.uk/medicines/alendronic-acid/
  4. https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/osteoporosis
  5. https://www.healthline.com/health/osteopenia#:~:text=Causes%20and%20risk%20factors%20of%20osteopenia&amp;text=That%20means%20you%20lose%20some,than%20age%2050%20get%20osteopenia.
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC15105/

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