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  3. Osteorol Nasal Spray 3.7 ml

Osteorol Nasal Spray 3.7 ml, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Osteorol Nasal Spray is used to treat Postmenopausal osteoporosis. It contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus, it helps to treat osteoporosis in postmenopausal women. Common side effects of Osteorol Nasal Spray are hypocalcemia, runny nose, nosebleed, sinus pain, application site reactions such as rhinitis (stuffy nose), epistaxis (nose bleeds) and other nasal symptoms, back pain, arthralgia (Joint pain) and headache.

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Synonym :

CALCITONIN SALMON

Composition :

CALCITONIN-2200IU

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Osteorol Nasal Spray

Osteorol Nasal Spray is primarily indicated for the treatment of postmenopausal osteoporosis in women more than five years postmenopause when alternative therapies are unsuitable. Post-menopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period.

Osteorol Nasal Spray contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus, it helps treat osteoporosis in postmenopausal women.

Use Osteorol Nasal Spray as prescribed by the doctor. Osteorol Nasal Spray may cause certain side effects such as hypocalcemia, runny nose, nosebleed, sinus pain, application site reactions such as rhinitis (stuffy nose), epistaxis (nose bleeds) and other nasal symptoms, back pain, arthralgia (Joint pain) and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Osteorol Nasal Spray is for intranasal use only; do not inject or take it orally. Before using Osteorol Nasal Spray , inform your doctor of all your medical conditions, sensitivities, and medications. Osteorol Nasal Spray is intended for post-menopausal women; therefore, it should not be recommended for other populations. Avoid drinking alcohol because it affects how the body absorbs calcium and vitamin D, which are essential for good bone formation.

Uses of Osteorol Nasal Spray

Osteorol Nasal Spray is used in the treatment of Postmenopausal osteoporosis. The detailed uses of Osteorol Nasal Spray are as follows:<br/>• Treat postmenopausal osteoporosis: Osteorol Nasal Spray helps slow bone loss and increase bone density in women who are at least five years past menopause. It reduces the risk of vertebral fractures by mimicking the natural hormone calcitonin, which regulates calcium levels and inhibits bone breakdown.<br/>• Manage bone pain in Paget’s disease: Osteorol Nasal Spray alleviates bone discomfort associated with abnormal bone remodeling in Paget’s disease by suppressing osteoclast activity and stabilizing bone turnover.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Remove the cap of the bottle, insert the tip into a nostril while closing the other nostril and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.• Wipe the nozzle with a clean tissue and replace the cap after each use.

Medicinal Benefits

Osteorol Nasal Spray contains Calcitonin, a calcitonin receptor agonist that prevents the loss of bones that happens after menopause and helps to rebuild bones. Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the parathyroid hormone's action, helping regulate the blood’s calcium and phosphate levels. Osteorol Nasal Spray works by suppressing the activity of the osteoclasts (cells that break down bone). When the osteoclasts break down bone tissue, the calcium enters the bloodstream. Osteorol Nasal Spray lessens the amount of calcium in the blood by preventing the breakdown of bone. Thereby, Osteorol Nasal Spray strengthens the bones and minimizes the risk of fractures. Osteorol Nasal Spray also seems to decrease the amount of calcium the kidneys can re-absorb, lowering calcium levels further.

How Osteorol Nasal Spray Works

Osteorol Nasal Spray contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus, it helps treat osteoporosis in postmenopausal women.

Storage

• Store in a cool and dry place away from sunlight.• Keep Osteorol Nasal Spray out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Osteorol Nasal Spray 3.7 ml
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Osteorol Nasal Spray

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Osteorol Nasal Spray may include nausea and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Before using Osteorol Nasal Spray , Inform your doctor about all your medical conditions, sensitivities, and all medications you are using. Osteorol Nasal Spray is intended for post-menopausal women; therefore, Osteorol Nasal Spray should not be recommended for other populations. In rare situations, individuals using Osteorol Nasal Spray may be affected with anaphylactic shock (a sudden, severe, life-threatening allergic reaction leading to difficulty breathing); if you encounter it, stop using Osteorol Nasal Spray and contact your doctor immediately.

Drug-Drug Interactions

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calcitonin (salmon synthetic)Etelcalcetide
Severe

Drug-Drug Interactions

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calcitonin (salmon synthetic)Etelcalcetide
Severe
How does the drug interact with Osteorol Nasal Spray 3.7 ml:
Etelcalcetide may decrease the calcium levels in the blood. Concomitant use with calcitonin may increase the risk of hypocalcemia, or low blood calcium.

How to manage the interaction:
Although there is an interaction, calcitonin can be taken with etelcalcetide if prescribed by the doctor. Consult the prescriber if you notice symptoms of hypocalcemia like numbness or tingling around your mouth, muscle spasms, or mental changes (irritability, depression, psychosis). Do not discontinue using any medication without contacting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume calcium-rich foods like milk, yoghurt, cheese, green leafy vegetables, fish with bones such as salmon, sardines, calcium-fortified cereals and orange juice.
  • Exposure to sunlight helps synthesise vitamin D, which is essential for strong bones and muscles.
  • Eating vitamin-D-rich foods such as egg yolks, salmon, oily fish like sardines, and mackerel.
  • Indulging in regular exercise to prevent bone loss. Activities include brisk walking, dancing, jogging, and strength training exercises like lifting weights and using weight machines or elastic bands.
  • Engaging in activities for stress relief, such as meditation and yoga.
  • Preserving a healthy weight eases pressure on the bones.
  • Taking medications if one is at risk for osteoporosis.
  • Quitting smoking and limiting alcohol consumption.

Habit Forming

No

Therapeutic Class

HYPOCALCEMIC AGENTS

Osteorol Nasal Spray Substitute

Substitutes safety advice
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Alcohol

Caution

Consuming alcohol is not advisable; it affects how the body absorbs calcium and vitamin D, both of which are essential for good bone formation.

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Pregnancy

Not applicable

Osteorol Nasal Spray is intended for postmenopausal women only. So, it is not recommended for use in pregnancy.

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Breast Feeding

Not applicable

Osteorol Nasal Spray is intended for postmenopausal women only. So, it is not recommended for use in breastfeeding women.

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Driving

Safe

Osteorol Nasal Spray does not impact your ability to drive or operate machinery.

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Liver

Caution

Limited information is available on the use of Osteorol Nasal Spray in patients with liver disease. Inform your doctor before receiving the Osteorol Nasal Spray if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information is available about using Osteorol Nasal Spray in patients with liver disease. Inform your doctor before receiving the Osteorol Nasal Spray if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Not applicable

Osteorol Nasal Spray is intended for postmenopausal women only. So, it is recommended not to use it in children.

FAQs

Osteorol Nasal Spray is used to treat Postmenopausal osteoporosis.

Osteorol Nasal Spray contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness).

If you have osteoporosis, avoid smoking, or try to quit. Tobacco use disrupts the mechanisms of bone turnover, resulting in reduced bone mass and bone mineral density (BMD), making bones prone to osteoporosis.

Osteorol Nasal Spray contains Calcitonin, a hormone that regulates the calcium level in the blood. This hormone helps in bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damages bones become comparatively less; hence the bone damage is halted. Using Osteorol Nasal Spray can increase bone formation by activation of the bone-forming cells.

Persons whose age is more than 45 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.

Yes, Osteorol Nasal Spray is used together with calcium and vitamin D to treat bone loss in women with postmenopausal osteoporosis who have been postmenopausal for at least five years. Osteorol Nasal Spray inhibits the function of osteoclasts (bone breakdown), reducing bone resorption; thus, combining calcium and calcitonin could result in a positive bone balance.

Store the unopened bottle in the refrigerator between 2°C- 8°C until ready to use, protect it from freezing. Osteorol Nasal Spray in use can be stored at room temperature between 15°C- 30°C for 35 days in an upright position. Keep it out of reach from children.

Osteorol Nasal Spray may increase the bone density. Osteorol Nasal Spray helps reduce bone loss and damage in individuals with osteoporosis. In certain cases, it also promotes bone formation by stimulating bone-building cells, which can lead to increased bone density.

You are not recommended to use Osteorol Nasal Spray if you are having any allergic reactions to calcitonin-salmon to avoid potential interactions. Therefore, please contact a doctor before using Osteorol Nasal Spray . Do not self-medicate.

When using Osteorol Nasal Spray , you are recommended to, inform your doctor if you have allergies to any of its active substances or a history of severe allergic reactions. Also, let them know if you are pregnant, planning to become pregnant, or breastfeeding. Calcitonin is not recommended for children. In rare cases, it may cause severe allergic reactions, such as bronchospasm, swelling of the tongue or throat, or anaphylactic shock. If any of these occur, seek immediate medical attention.

Osteorol Nasal Spray is not recommended for use during pregnancy or breastfeeding. It is intended only for postmenopausal women. However, if you have any concerns, contact your doctor.

Osteorol Nasal Spray causes side effects such as back pain, headache, muscle pain, and runny nose. However, these will gradually reduce over time and do not require any medical attention. Please, consult a doctor if persists longer.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - OST0150

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:03 AM IST

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Reference

  1. https://www.drugs.com/cdi/calcitonin-injection.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020313s036lbl.pdf
  3. https://www.hormone.org/your-health-and-hormones/glands-and-hormones-a-to-z/hormones/calcitonin
  4. https://creakyjoints.org/diet-exercise/alcohol-and-osteoporosis/#:~:text=Alcohol%20consumption%20impacts%20how%20the,Boden.
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517743/#:~:text=Calcitonin%20(CT)%2C%20a%2032,2%2B%20excretion%20by%20the%20kidney.

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