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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ovalet 2.5 Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Letrozole, which prevents the growth of cancer cells. Thereby, it helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts. It may cause certain common side effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

LETROZOLE-2.5MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Ovalet 2.5 Tablet

Ovalet 2.5 Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
Ovalet 2.5 Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Ovalet 2.5 Tablet prevents the growth of cancer cells. Thereby Ovalet 2.5 Tablet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Ovalet 2.5 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Ovalet 2.5 Tablet may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
Avoid taking Ovalet 2.5 Tablet if you are pregnant or breastfeeding. Ovalet 2.5 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Ovalet 2.5 Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Ovalet 2.5 Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Ovalet 2.5 Tablet

Ovalet 2.5 Tablet is used in the treatment of Breast cancer. The detailed uses of Ovalet 2.5 Tablet are as follows:
•Breast Cancer Treatment: Ovalet 2.5 Tablet is primarily prescribed for postmenopausal women with hormone-receptor-positive breast cancer. It works by lowering estrogen levels, which helps slow or halt the growth of certain breast tumors.
•Adjuvant Therapy: After surgery for early-stage breast cancer, Ovalet 2.5 Tablet may be used as adjuvant therapy to reduce the risk of recurrence and improve survival rates.
•Neoadjuvant Therapy: Ovalet 2.5 Tablet can serve as a neoadjuvant treatment to shrink breast tumors before surgery, facilitating their removal.
•Ovarian Function Suppression: Ovalet 2.5 Tablet is occasionally used off-label during fertility treatments to suppress ovarian function, particularly in cases of polycystic ovary syndrome (PCOS).

Directions for Use

Take Ovalet 2.5 Tablet with or without food. Swallow Ovalet 2.5 Tablet as a whole with a glass of water; do not chew or break it. Take Ovalet 2.5 Tablet at the same time every day.

Medicinal Benefits

Ovalet 2.5 Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors. Ovalet 2.5 Tablet is used to treat breast cancer in women who have gone through menopause (cessation of periods). Ovalet 2.5 Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Ovalet 2.5 Tablet prevents the growth of cancer cells. Thereby, Ovalet 2.5 Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

How Ovalet 2.5 Tablet Works

Ovalet 2.5 Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Ovalet 2.5 Tablet prevents the growth of cancer cells. Thereby Ovalet 2.5 Tablet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ovalet 2.5 Tablet

  • Hypercholesterolemia (increased cholesterol levels)
  • Tiredness
  • Weakness
  • Increased sweating
  • Feeling unwell
  • Pain in joints
  • Hot flushes (feeling of warmth)

What if I have taken an overdose of Ovalet 2.5 Tablet

Do not take more than the prescribed dose of Ovalet 2.5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Ovalet 2.5 Tablet if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Ovalet 2.5 Tablet if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Ovalet 2.5 Tablet may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Ovalet 2.5 Tablet. Avoid taking Ovalet 2.5 Tablet if you are pregnant or breastfeeding. Ovalet 2.5 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Ovalet 2.5 Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Ovalet 2.5 Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Ovalet 2.5 Tablet to rule out any side-effects. 

Drug-Drug Interactions

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LetrozoleEstrone
Severe
LetrozoleEstradiol
Severe

Drug-Drug Interactions

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LetrozoleEstrone
Severe
How does the drug interact with Ovalet 2.5 Tablet:
When taken together Ovalet 2.5 Tablet's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEstradiol
Severe
How does the drug interact with Ovalet 2.5 Tablet:
Ovalet 2.5 Tablet may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleThalidomide
Severe
How does the drug interact with Ovalet 2.5 Tablet:
Coadministration of thalidomide and Ovalet 2.5 Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleDiethylstilbestrol
Severe
How does the drug interact with Ovalet 2.5 Tablet:
Co-administration of Ovalet 2.5 Tablet may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleCitalopram
Severe
How does the drug interact with Ovalet 2.5 Tablet:
Co-administration of Ovalet 2.5 Tablet and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleEstramustine
Severe
How does the drug interact with Ovalet 2.5 Tablet:
when taken together Ovalet 2.5 Tablet's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleDesogestrel
Severe
How does the drug interact with Ovalet 2.5 Tablet:
Co-administration of Desogestrel together with Ovalet 2.5 Tablet may decrease the effects of Ovalet 2.5 Tablet.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with Ovalet 2.5 Tablet:
Coadministration of Conjugated estrogens with Ovalet 2.5 Tablet may reduce the effect of Ovalet 2.5 Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Ovalet 2.5 Tablet together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
LetrozoleEthinylestradiol
Severe
How does the drug interact with Ovalet 2.5 Tablet:
When taken together ethinyl estradiol may interfere with Ovalet 2.5 Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Ovalet 2.5 Tablet and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.

  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Ovalet 2.5 Tablet Substitute

Substitutes safety advice
  • Letroz Tablet 5's

    by Others

    29.52per tablet
  • Femara 2.5 mg Tablet 10's

    by Others

    28.86per tablet
  • Letroz Tablet 30's

    by AYUR

    29.54per tablet
  • Fempro Tablet 10's

    by Others

    8.01per tablet
  • Letoval Tablet 5's

    by Others

    29.52per tablet
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Ovalet 2.5 Tablet to avoid unpleasant side effects. Alcohol intake, along with Ovalet 2.5 Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Ovalet 2.5 Tablet is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Ovalet 2.5 Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Caution

Ovalet 2.5 Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Ovalet 2.5 Tablet if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Ovalet 2.5 Tablet if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this. No dosage adjustment is required for kidney patients with creatinine clearance greater than 10 mL/min.

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Children

Unsafe

Ovalet 2.5 Tablet should not be used by children, as the efficacy and safety have not been established.

FAQs

Ovalet 2.5 Tablet belongs to the group of anti-cancer medicines used to treat breast cancer in women.

Ovalet 2.5 Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Ovalet 2.5 Tablet prevents the growth of cancer cells. Thereby, Ovalet 2.5 Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Ovalet 2.5 Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Ovalet 2.5 Tablet. Regularly monitor blood pressure levels while taking Ovalet 2.5 Tablet. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Ovalet 2.5 Tablet on your own. You are advised to take Ovalet 2.5 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Ovalet 2.5 Tablet.

Ovalet 2.5 Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Ovalet 2.5 Tablet.

Ovalet 2.5 Tablet may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.

Ovalet 2.5 Tablet should be swallowed as a whole with water; do not crush or chew it.

Ovalet 2.5 Tablet can be taken with or without food.

Ovalet 2.5 Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Ovalet 2.5 Tablet is prescribed to treat breast cancer in women who have gone through menopause.

Ovalet 2.5 Tablet may cause high blood pressure. Therefore, irbesartan should be taken with Ovalet 2.5 Tablet only if prescribed by the doctor. Regularly monitor blood pressure levels while taking Ovalet 2.5 Tablet.

Ovalet 2.5 Tablet may cause eye problems like blurred vision and cataracts. Consult the doctor if you experience blurred vision or eye irritation.

Ovalet 2.5 Tablet may cause hot flushes leading to sweating. These symptoms usually improve during the first few months. However, if the symptoms persist or worsen, consult the doctor.

Serious side effects of Ovalet 2.5 Tablet are difficulty breathing, chest pain, fainting, rapid heart rate, formation of blood clots (bluish skin discolouration, or sudden arm, leg or foot pain) and rupture of a tendon. These side effects are rare and may not occur in everyone taking Ovalet 2.5 Tablet.

Letrozole may induce ovulation in anovulatory infertility patients and augment follicles for ovulatory women. However, it is an off-label use. Talk to the doctor if you have any concerns.

Ovalet 2.5 Tablet is not recommended for use during pregnancy or while breastfeeding.

The time required for Ovalet 2.5 Tablet to show its effects depends upon your condition and severity. Consult the doctor if you have any concerns.

If you miss a dose of Ovalet 2.5 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Ovalet 2.5 Tablet may interact with antidepressants (citalopram, escitalopram) and anticancer medicines (tamoxifen). Let the doctor know if you are taking these medicines.

Store Ovalet 2.5 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Country of origin

India
Other Info - OV71173

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