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compositionComposition:CETRORELIX-0.25MG
prescription
Prescription Medicine
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Ovucet PFS 0.25 mg Injection 0.5 ml is used to treat female infertility. It contains Cetrorelix which works by blocking a natural hormone in the body and inhibits premature ovulation. In some cases, this medicine may cause side effects such as itching, redness, or swelling at the site of injection, headache, or nausea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CETRORELIX-0.25MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Ovucet PFS 0.25 mg Injection 0.5 ml

Ovucet PFS 0.25 mg Injection 0.5 ml is a prescription injection used to support fertility treatments, specifically assisted reproductive technologies like in vitro fertilisation (IVF). It is prescribed to prevent your ovaries from releasing eggs too early, which ensures they can mature properly before collection. This medical purpose is vital for helping increase the chances of a successful pregnancy.

This medicine must be injected consistently at the same time every day to maintain its protective effect on your cycle. Since it is given as an injection under the skin, its absorption is not affected by whether you take it with or without food. Combining this treatment with healthy habits, like eating a balanced diet and reducing physical and emotional stress, can help support your body's response to the fertility cycle.

Many women experience only mild reactions at the injection site, such as redness, itching, or swelling. However, it is essential to contact your doctor immediately if you experience severe symptoms like intense abdominal pain, bloating, or trouble breathing, which could indicate a serious condition called ovarian hyperstimulation syndrome.

Before starting this medication, talk to your doctor if you have a history of active allergies or severe kidney or liver damage. Specifically, you should not take this medicine if you are already pregnant, breastfeeding, or suffer from severe kidney damage.

Be sure to inform your healthcare provider about all other medicines you are taking, as well as your alcohol and smoking habits, because they can alter your body's hormonal response and impact the success of your fertility treatment. Additionally, this medication is not intended for pregnant or breastfeeding women, nor is it designed for use in elderly individuals.

Uses of Ovucet PFS 0.25 mg Injection 0.5 ml

Ovucet PFS 0.25 mg Injection 0.5 ml is commonly used during fertility treatment to help control the timing of ovulation and improve the success of assisted reproductive procedures.

  • Premature ovulation in fertility cycles: During controlled ovarian stimulation, your body may try to release eggs before they are fully mature. Ovucet PFS 0.25 mg Injection 0.5 ml blocks the chemical trigger that starts ovulation, allowing the eggs to develop completely so your doctor can safely collect them during IVF.
  • Assisted Reproductive Technology (ART) cycle control: In complex fertility cycles, precise timing is essential. This medicine helps coordinate and control your hormonal cycle, giving your medical team the predictable window they need to perform the egg retrieval procedure successfully.

Key Benefits

Ovucet PFS 0.25 mg Injection 0.5 ml offers several benefits by helping control ovulation and supporting the success of fertility treatment.

  • Helps prevent premature ovulation: Ovucet PFS 0.25 mg Injection 0.5 ml reduces the risk of eggs being released too early, helping ensure they can be collected at the right time during IVF or other assisted reproductive procedures.
  • Supports successful fertility treatment: By allowing precise control over the timing of ovulation, Ovucet PFS 0.25 mg Injection 0.5 ml helps optimise egg retrieval and supports a well-coordinated fertility treatment cycle.
Side effects of Ovucet PFS 0.25 mg Injection 0.5 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Stay hydrated by drinking plenty of water to help reduce swelling.
  • Include anti-inflammatory foods like turmeric, ginger, and omega-3 rich foods in your diet.
  • Avoid processed and high-sodium foods that can exacerbate swelling.
  • Utilize an ice pack wrapped in a cloth to cool the affected area, helping to alleviate swelling and discomfort.
  • Gently massage the site, if recommended by your healthcare provider, to promote lymphatic drainage.
  • Rotate injection sites to minimize irritation and swelling.
  • Allow your body time to rest and recuperate, limiting physically demanding tasks to facilitate a smoother recovery.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions and use it as advised by the doctor.
  • Ovucet PFS 0.25 mg Injection 0.5 ml should be injected into the lower abdomen, at least one inch away from the belly button.
  • Choose a different injection site each day to minimize irritation.

How Ovucet PFS 0.25 mg Injection 0.5 ml Works

Ovucet PFS 0.25 mg Injection 0.5 ml contains cetrorelix, which works as a gonadotropin-releasing hormone (GnRH) blocker. In a natural menstrual cycle, your brain releases a hormone called GnRH, which signals your body to produce luteinizing hormone (LH). This surge in LH is what triggers your ovaries to release an egg. When you undergo fertility treatments, your doctor uses other hormones to stimulate the growth of multiple eggs. However, this growth can cause a premature LH surge, prompting your body to release the eggs too early. Ovucet PFS 0.25 mg Injection 0.5 ml immediately binds to GnRH receptors, blocking their activity. By doing this, it stops the LH surge in its tracks, keeping your eggs safely in place until they are fully mature and ready for your medical team to retrieve.
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Alcohol

Caution

The interaction of Ovucet PFS 0.25 mg Injection 0.5 ml with alcohol is unknown. Please consult a doctor before consuming alcohol while using Ovucet PFS 0.25 mg Injection 0.5 ml.

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Pregnancy

Unsafe

Ovucet PFS 0.25 mg Injection 0.5 ml is a category X pregnancy drug and is not recommended for use during pregnancy as it may cause miscarriage, stillbirth, or birth defects. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Ovucet PFS 0.25 mg Injection 0.5 ml is contraindicated in breastfeeding women. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Ovucet PFS 0.25 mg Injection 0.5 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Ovucet PFS 0.25 mg Injection 0.5 ml in patients with Liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding using Ovucet PFS 0.25 mg Injection 0.5 ml in patients with kidney problems, please consult a doctor. Avoid using Ovucet PFS 0.25 mg Injection 0.5 ml if you have severe kidney disease.

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Children

Unsafe

Ovucet PFS 0.25 mg Injection 0.5 ml is not recommended for children.

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Heart

Caution

Limited information was available regarding the use of Ovucet PFS 0.25 mg Injection 0.5 ml in patients with heart problems. Please consult your doctor before receiving Ovucet PFS 0.25 mg Injection 0.5 ml.

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Geriatrics

Caution

Limited information is available regarding the use of Ovucet PFS 0.25 mg Injection 0.5 ml in elderly patients. If you have any concerns about the usage of Ovucet PFS 0.25 mg Injection 0.5 ml in geriatrics, please consult your doctor.

What if I have taken an overdose of Ovucet PFS 0.25 mg Injection 0.5 ml

If you inject more of this medicine than prescribed, seek medical attention immediately. While an accidental extra dose is unlikely to cause severe or life-threatening symptoms, it can alter your cycle's hormonal balance and needs to be evaluated by your fertility specialist.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of water throughout the day to help manage bloating and support overall health.
  • Eat a balanced diet: Include healthy fats, leafy green vegetables, lean proteins, and whole grains to support reproductive health.
  • Exercise gently: Choose low-impact activities such as walking, and avoid heavy lifting or high-impact exercise during ovarian stimulation unless advised by your doctor.
  • Manage stress: Practice deep breathing, mindfulness, or other relaxation techniques to support your emotional well-being during treatment.
  • Avoid smoking and alcohol: Smoking and alcohol may reduce fertility treatment success and should be avoided during your IVF cycle.
health query

Have a query?

How Soon It Starts Working

The time required for Ovucet PFS 0.25 mg Injection 0.5 ml to start to work: Ovucet PFS 0.25 mg Injection 0.5 ml ideally shows its action within 1 hour of administration of the 3 mg dose and within 2 hours of administration of the 0.25 mg dose. The time for which the effects of Ovucet PFS 0.25 mg Injection 0.5 ml last: The effect of Ovucet PFS 0.25 mg Injection 0.5 ml lasts for 4 to 6 hours.

What if you forget to take Ovucet PFS 0.25 mg Injection 0.5 ml

If you miss a dose, contact your fertility clinic or doctor immediately for advice. Because timing is critical to prevent premature ovulation, missing a dose by even a few hours can disrupt your entire treatment cycle. Do not inject a double dose to make up for a missed one unless specifically instructed by your healthcare provider.

Storage

• Store Ovucet PFS 0.25 mg Injection 0.5 ml in its original carton to protect the medication from direct light.

Drug Warnings

  • Inspect before use: Ensure the solution is clear and colourless. Do not use it if it appears cloudy, discoloured, or contains particles.
  • Rotate injection sites: Change the injection site on your lower abdomen each day to help reduce skin irritation and bruising.
  • Use a new needle each time: Never reuse needles or syringes. Always use a new sterile needle for every injection.
  • Complete your treatment: Make sure you have enough medication to finish your prescribed cycle and avoid missing doses.
  • Watch for warning signs: Contact your doctor immediately if you develop sudden weight gain, severe pelvic pain, or significant abdominal bloating, as these may be signs of ovarian hyperstimulation syndrome (OHSS).

Drug-Drug Interactions

verifiedApollotooltip

  • While no specific severe drug interactions have been established, always inform your doctor about other hormonal therapies or medications you are taking, as they may influence how your body responds to fertility treatment.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Ovucet PFS 0.25 mg Injection 0.5 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Ovucet PFS 0.25 mg Injection 0.5 ml contains Cetrorelix that works by blocking a natural hormone in the body and inhibits premature ovulation (release of eggs from the ovary too early).
Ovucet PFS 0.25 mg Injection 0.5 ml may cause ovarian hyper-stimulation syndrome (OHSS) if used along with other medicines that cause stimulation of ovaries to develop more ready-to-be-released eggs. However, if you experience lower stomach pain with nausea or vomiting, please consult a doctor as these might be signs of OHSS.
Ovucet PFS 0.25 mg Injection 0.5 ml may be used in women undergoing IVF (in-vitro fertilization) treatment to prevent premature release of eggs so that mature eggs can be collected directly from ovaries. However, please consult a doctor before using Ovucet PFS 0.25 mg Injection 0.5 ml.
You are recommended to consult a doctor before using Ovucet PFS 0.25 mg Injection 0.5 ml during more than 1 menstrual cycle so that the doctor may check the benefits and risks of using Ovucet PFS 0.25 mg Injection 0.5 ml.
Ovucet PFS 0.25 mg Injection 0.5 ml may cause miscarriage, birth defects, or stillbirth. Therefore, avoid Ovucet PFS 0.25 mg Injection 0.5 ml if you are pregnant and consult a doctor.
You are advised to follow instructions given by your doctor if you are taking Ovucet PFS 0.25 mg Injection 0.5 ml at home. Inject Ovucet PFS 0.25 mg Injection 0.5 ml under the belly's skin and select different parts of your belly every day to minimize skin irritation.
Ovucet PFS 0.25 mg Injection 0.5 ml is an anti-gonadotropin-releasing hormone medicine. It is used for the prevention of premature ovulation in patients undergoing controlled ovarian stimulation.
Possible side effects of Ovucet PFS 0.25 mg Injection 0.5 ml are itching, redness, or swelling at the site of injection, headache, or nausea. If any of these side effects persist or worsen, please consult your doctor.
Timing is critical because the medicine blocks the ovulation-triggering hormone for only about 24 hours. Injecting it at the same time each day ensures there are no gaps in protection, which prevents your ovaries from releasing the eggs too early. Talk to your doctor if you are unsure about your injection schedule.
Mild redness, itching, or swelling is a common reaction that usually goes away on its own within a few hours. To help prevent this, ensure you rotate your injection sites daily and do not rub the area after injecting. Talk to your doctor or pharmacist if the skin irritation gets worse or does not clear up.
During IVF, your ovaries are stimulated to grow multiple eggs. Ovucet PFS 0.25 mg Injection 0.5 ml prevents your body from prematurely releasing these eggs before your doctor can collect them, helping to ensure a successful retrieval process. Talk to your doctor for more details about your specific IVF protocol.
Generally, this medicine must be stored in the refrigerator between 2°C and 8°C. Some formulations can be kept at room temperature for a very limited time, but you should always consult the specific package instructions or talk to your pharmacist to ensure your storage method is safe.
You will typically use this medicine for a few consecutive days during the middle to late phase of your ovarian stimulation cycle. Your fertility doctor will monitor your egg growth using ultrasounds and tell you exactly when to start and stop the injections. Talk to your doctor to understand your customised treatment timeline.
Yes, this medication does not typically affect your ability to drive or operate machinery. However, if you feel dizzy, tired, or unwell after your injection, you should avoid driving until you feel better. Talk to your doctor if you experience persistent dizziness or fatigue.
Your fertility specialist monitors your ovarian response using ultrasound scans and blood hormone (estradiol) tests. These results determine the most appropriate time to start Ovucet PFS 0.25 mg Injection 0.5 ml to help prevent premature ovulation.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - OVU0056
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