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Pacin Bru 400mg/325mg Tablet is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever. Pain can be temporary (acute) or long-lasting (chronic).
Pacin Bru 400mg/325mg Tablet contains Ibuprofen and Paracetamol. This medicine works by blocking the effect of prostaglandin, which is responsible for inducing pain and inflammation in the body.
Like all medicines, Pacin Bru 400mg/325mg Tablet may cause side effects, although not everybody gets them. Stop taking this medicine if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, or any signs of hypersensitivity.
Inform your doctor if you are allergic to any of the components present in it. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Avoid consumption of alcohol as it may damage your liver and cause increased side effects on taking this drug.
Pacin Bru 400mg/325mg Tablet is used for the treatment of Pain and Fever. The detailed uses of Pacin Bru 400mg/325mg Tablet are as follows:
Unsafe
Taking Pacin Bru 400mg/325mg Tablet with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with Pacin Bru 400mg/325mg Tablet.
Unsafe
Use of Pacin Bru 400mg/325mg Tablet during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.
Consult your doctor
Take Pacin Bru 400mg/325mg Tablet only if prescribed by your doctor.
Unsafe
After taking Pacin Bru 400mg/325mg Tablet you may notice dizziness, sleepiness, drowsiness or fatigue.
Caution
Pacin Bru 400mg/325mg Tablet to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.
Caution
Pacin Bru 400mg/325mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.
Caution
Pacin Bru 400mg/325mg Tablet is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.
Unsafe
Pacin Bru 400mg/325mg Tablet should be avoided in cardiac patients as it can lead to serious cardiavascular risks
Caution
Pacin Bru 400mg/325mg Tablet should be used under caution in geriatric patients as it can lead to serious side effects.

Have a query?
The time required for Pacin Bru 400mg/325mg Tablet to start to work: The time required for Pacin Bru 400mg/325mg Tablet to show its action is unknown.
The time for which the effects of Pacin Bru 400mg/325mg Tablet last: The duration of action for Pacin Bru 400mg/325mg Tablet is unknown.
Drug Interactions: Pacin Bru 400mg/325mg Tablet is shown to interact with various drugs. Some of them include lithium, blood thinner or anticoagulant (warfarin, ticlopidine), anti-arthritis pills (methotrexate), blood pressure or heart medicine, nausea/vomiting medicine (metoclopramide, domperidone), diuretic/water pills (thiazides, furosemide), steroid medicine (prednisone), quinolones antibiotics (ciprofloxacin), respiratory medicines (theophylline, ephedrine), cholesterol-reducing medicine (colestyramine) and antidepressants (duloxetine). These drugs may affect the working of Pacin Bru 400mg/325mg Tablet and may alter its efficacy.
Drug-Food Interactions: Pacin Bru 400mg/325mg Tablet interacts with alcoholic beverages and increases your risk of stomach bleeding.
Drug-Disease Interactions: Pacin Bru 400mg/325mg Tablet should not be recommended for people having the liver disease (like Gilbert’s syndrome in which the liver does not process bile), asthma, allergic skin diseases (Stevens-Johnson syndrome, toxic epidermal necrolysis), blood clot disorder, high blood pressure (hypertension), or history of heart failure. Besides this, Pacin Bru 400mg/325mg Tablet should not be given to the children suffering from influenza (flu) or chickenpox. It should also be avoided in case of the presence of gastric/duodenal ulcers and low glutathione levels.
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Pacin Bru 400mg/325mg Tablet is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever.
Pacin Bru 400mg/325mg Tablet is comprised of two medications, Ibuprofen and Paracetamol. Pacin Bru 400mg/325mg Tablet has analgesic and anti-inflammatory properties that help relieve mild to moderate pain. Pacin Bru 400mg/325mg Tablet functions by inhibiting the production of specific chemical messengers that induce fever, discomfort, and inflammation (redness and swelling).
No, it is not advisable to take Pacin Bru 400mg/325mg Tablet with depression medication. Please inform your doctor if you are taking depression medicine before starting Pacin Bru 400mg/325mg Tablet.
Yes, Pacin Bru 400mg/325mg Tablet is a short term medication and if you feel better you can stop taking Pacin Bru 400mg/325mg Tablet, but only after consulting your doctor.
Pacin Bru 400mg/325mg Tablet is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.
Yes, Pacin Bru 400mg/325mg Tablet is known to cause dizziness. If you feel dizzy, please take rest and also avoid driving while you take Pacin Bru 400mg/325mg Tablet as it can be harmful.
No, Pacin Bru 400mg/325mg Tablet is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer, or gastric bleeding. Do not take Pacin Bru 400mg/325mg Tablet in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.
It depends on whether your cough and cold pills contain ibuprofen and paracetamol or not. If it contains these two medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.
Pacin Bru 400mg/325mg Tablet is known to cause stomach upset in some cases. So, please take Pacin Bru 400mg/325mg Tablet with a meal or a glass of milk to avoid upset stomach.
No, Pacin Bru 400mg/325mg Tablet should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Pacin Bru 400mg/325mg Tablet, please take it in doses and duration mentioned by your doctor.
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