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Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Pagenax 120 mg/ml Injection 1's

Pagenax 120 mg/ml Injection 1's is used to treat eye conditions that may affect your vision, such as neovascular (wet) age-related macular degeneration (AMD) and diabetic macular edema (DME). AMD is a condition that leads to vision loss due to the formation of abnormal blood vessels in the retina. DME is a complication of diabetes that causes swelling in the macula, the part of the retina responsible for sharp, central vision.

Pagenax 120 mg/ml Injection 1's contains brolucizumab, which is a monoclonal antibody. It blocks VEGF (vascular endothelial growth factor), a protein involved in the formation of abnormal blood vessels in the retina. This helps reduce fluid leakage, prevent further vision loss, and improve vision in patients with these eye conditions. 

A healthcare professional will administer Pagenax 120 mg/ml Injection 1's. This medicine may sometimes cause side effects, such as eye discomfort, redness, or increased intraocular pressure. Most of these side effects do not require medical treatment and will subside with time. However, if they persist or worsen, see a doctor.

Pagenax 120 mg/ml Injection 1's should not be received if you are allergic to it. Let your doctor know if you have ever had any eye diseases such as glaucoma, dark floating spots, retinal vascular occlusion, retinal vasculitis, or any previous eye treatments before receiving Pagenax 120 mg/ml Injection 1's. If you are pregnant or breastfeeding, please consult a doctor before taking Injection. Pagenax 120 mg/ml Injection 1's is not recommended for children, as its safety and efficacy have not been established.

Uses of Pagenax 120 mg/ml Injection 1's

Pagenax 120 mg/ml Injection 1's is used to treat wet age-related macular degeneration (AMD) and diabetic macular edema (DME). The detailed uses of Pagenax 120 mg/ml Injection 1's are as follows:<br/>• Wet Age-Related Macular Degeneration (AMD) Treatment: Pagenax 120 mg/ml Injection 1's treats wet AMD by blocking VEGF-A, reducing abnormal blood vessel growth and leakage, slowing disease progression, and preserving vision.<br/>• Diabetic Macular Edema (DME) Treatment: Pagenax 120 mg/ml Injection 1's treats diabetic macular edema (DME) by blocking VEGF-A, reducing fluid leakage and swelling in the retina, and improving vision.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Pagenax 120 mg/ml Injection 1's should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications.• Do not self-administer.

Medicinal Benefits

Pagenax 120 mg/ml Injection 1's provides significant benefits for patients with wet AMD and DME because it reduces abnormal blood vessel formation and fluid leakage. This helps to prevent vision loss and improve vision. The drug is supplied directly into the eye via pre-filled injection, usually on a predetermined schedule that changes based on the patient's response. Pagenax 120 mg/ml Injection 1's blocks VEGF (vascular endothelial growth factor), a protein involved in the formation of abnormal blood vessels in the retina. This helps reduce fluid leakage, prevent further vision loss, and improve vision in patients with these eye conditions.

How Pagenax 120 mg/ml Injection 1's Works

Vascular endothelial growth factor (VEGF) is a protein that helps new blood vessels grow. Sometimes, abnormal blood vessels start growing under the retina in certain eye conditions. These abnormal vessels can leak fluid and bleed, causing damage to the macula, the central part of the retina responsible for sharp vision. This can lead to severe vision loss and blurry vision in the centre of your sight. Pagenax 120 mg/ml Injection 1's works by blocking the VEGF protein. Doing this helps reduce the growth and leakage of these abnormal blood vessels in the retina, protecting your vision.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Pagenax 120 mg/ml Injection 1's

Pagenax 120 mg/ml Injection 1's is administered in a hospital setting by a healthcare professional, and the likelihood of an overdose is much less. However, if you suspect an overdose or experience any adverse effects, seek medical attention immediately.

Drug Warnings

Let the doctor know if you are allergic to the Pagenax 120 mg/ml Injection 1's. Before starting treatment with Pagenax 120 mg/ml Injection 1's, inform your doctor about any other medications or herbal products you are taking. If you are pregnant or nursing, speak with your doctor. Pagenax 120 mg/ml Injection 1's is not recommended for use in conditions like ocular/periocular infections and active intraocular infections. Tell your doctor if you have a history of eye disorders such as glaucoma, dark floating spots, retinal vascular occlusion, retinal vasculitis, or any past eye treatments. Pagenax 120 mg/ml Injection 1's is not recommended for children under 18 years old.

Diet & Lifestyle Advise

  • Consume a balanced diet high in leafy greens, seafood, nuts, and citrus fruits.
  • Stay hydrated for better general and eye health.
  • Control your blood sugar and blood pressure to avoid worsening eye issues.
  • To decrease retinal damage, avoid smoking and consuming alcohol.
  • Regular exercise improves circulation and overall well-being.
  • Wear UV-blocking sunglasses to protect your eyes.
  • Schedule regular eye exams to monitor your condition.

Habit Forming

No

Therapeutic Class

OPHTHALMOLOGIC AGENTS
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Alcohol

Consult your doctor

It is unknown if alcohol interacts with Pagenax 120 mg/ml Injection 1's. Please consult a doctor if you have any concerns.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform the doctor before receiving Pagenax 120 mg/ml Injection 1's. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data exist on the use of Pagenax 120 mg/ml Injection 1's during breastfeeding. Consult your healthcare provider to assess the risks and benefits.

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Driving

Unsafe

Pagenax 120 mg/ml Injection 1's may affect vision temporarily. Avoid driving or operating heavy machinery if you experience visual disturbances after the injection.

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Liver

Caution

Dose adjustment may be needed in case of moderate to severe liver impairment patients. Hence, inform your doctor if you have kidney disease before receiving Pagenax 120 mg/ml Injection 1's. Your doctor will prescribe Pagenax 120 mg/ml Injection 1's only if the benefits overweigh risks.

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Kidney

Caution

Dose adjustment may be needed in case of moderate to severe kidney impairment patients. Hence, inform your doctor if you have kidney disease before receiving Pagenax 120 mg/ml Injection 1's. Your doctor will prescribe Pagenax 120 mg/ml Injection 1's only if the benefits overweigh risks.

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Children

Unsafe

Pagenax 120 mg/ml Injection 1's is not recommended for children below 18 years, as its safety and efficacy have not been established.

Have a query?

FAQs

Pagenax 120 mg/ml Injection 1's is used to treat wet age-related macular degeneration (AMD) and diabetic macular edema (DME).

Pagenax 120 mg/ml Injection 1's works by targeting and blocking VEGF (vascular endothelial growth factor). VEGF promotes the growth of abnormal blood vessels in the eye, which can lead to fluid leakage and vision impairment. By inhibiting VEGF, Pagenax 120 mg/ml Injection 1's reduces fluid buildup and maintains retinal health.

Common side effects include eye discomfort, redness, and increased intraocular pressure. If the symptoms persist or worsen, seek medical attention.

Pregnant or breastfeeding women should consult their healthcare provider before using Pagenax 120 mg/ml Injection 1's, as its safety during pregnancy and breastfeeding is not fully established.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - PAG0011

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