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  3. Pamorelin La 22.5Mg Inj

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Pamorelin La 22.5Mg Inj, Pack of 1 Injection
Pamorelin La 22.5Mg Inj, Pack of 1 Injection
Pamorelin La 22.5Mg Inj, Pack of 1 Injection
Pamorelin La 22.5Mg Inj, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Pamorelin La 22.5Mg Inj is used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. It contains Triptorelin which works by inhibiting the synthesis of testosterone in men and oestrogen in women. In some cases, this medicine may cause side effects such as hot flashes, dizziness, headache, flu symptoms, nausea, vomiting, diarrhoea, upset stomach and swelling in the legs. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

TRIPTORELIN-22.5MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Pamorelin La 22.5Mg Inj

Pamorelin La 22.5Mg Inj belongs to the class of 'anti-neoplastic agents', primarily used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Pamorelin La 22.5Mg Inj contains Triptorelin that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. Triptorelin is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. The lowering of testosterone hormone levels in men helps slows down the growth of cancer cells in prostate cancer.

Use Pamorelin La 22.5Mg Inj as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Pamorelin La 22.5Mg Inj include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, flu symptoms, nausea, vomiting, diarrhoea, upset stomach and swelling in legs. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Pamorelin La 22.5Mg Inj, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Pamorelin La 22.5Mg Inj is not indicated for use in pregnant and breastfeeding women. Pamorelin La 22.5Mg Inj may make you feel dizzy, hence drive when you are alert only. Pamorelin La 22.5Mg Inj is not recommended for children below two years of age.

Uses of Pamorelin La 22.5Mg Inj

Pamorelin La 22.5Mg Inj is used in the treatment of Prostate cancer, endometriosis and precocious puberty. The detailed uses of Pamorelin La 22.5Mg Inj are as follows:

  • Advanced Prostate Cancer (in men): Pamorelin La 22.5Mg Inj is commonly prescribed for the palliative treatment of prostate cancer. It works by lowering testosterone levels, which helps slow the growth of hormone-sensitive cancer cells.
  • Central Precocious Puberty (in children): Pamorelin La 22.5Mg Inj is used in boys and girls (typically age 2 and older) to treat early onset puberty. It helps delay further sexual development until the appropriate age.
  • Endometriosis and Uterine Fibroids (in women): Pamorelin La 22.5Mg Inj reduces estrogen levels, helping manage symptoms like pelvic pain and heavy bleeding.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Pamorelin La 22.5Mg Inj will be administered by the doctor or nurse in a healthcare setting.
  • Do not self-administer.

Medicinal Benefits

Pamorelin La 22.5Mg Inj contains Triptorelin, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Pamorelin La 22.5Mg Inj is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Pamorelin La 22.5Mg Inj works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Pamorelin La 22.5Mg Inj reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis. Pamorelin La 22.5Mg Inj also has the role of a contraceptive drug.

How Pamorelin La 22.5Mg Inj Works

Pamorelin La 22.5Mg Inj contains Triptorelin that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. Triptorelin is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. The lowering of testosterone hormone levels in men helps slows down the growth of cancer cells in prostate cancer.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Pamorelin La 22.5Mg Inj
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.
  • Rest well; get enough sleep. This helps the body fight infection.
  • Keep yourself hydrated by drinking enough water and other fluids.
  • Wash your hands often and avoid touching your eyes, mouth or nose.
  • Wear a mask whilst going out.
  • Warm steam or a hot shower may help with nose secretions.
  • Avoid contact with others to prevent contamination.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Boost immunity with vitamins by including foods rich in vitamins C (citrus fruits, bell peppers) and D (fortified milk, fatty fish).
  • Eat omega-3 rich foods like fatty fish like salmon, tuna, and sardines to reduce inflammation.
  • Stay hydrated by drinking plenty of fluids to thin mucus and aid drainage.
  • Consider probiotic-rich foods like yogurt to potentially help prevent future ear infections.
  • Limit dairy and sugar intake to manage mucus production.
  • Sleep with head elevated by using extra pillows to facilitate fluid drainage.
  • Apply warm compress for temporary pain relief.
  • Wash hands frequently to prevent spreading germs.
  • Use a humidifier to add moisture to the air to help with congestion and ear pressure.
  • Avoid secondhand smoke to reduce risk of ear infections.
  • Consult your doctor before making significant dietary or lifestyle changes, especially if taking medication for ear infection.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Pamorelin La 22.5Mg Inj

Since Pamorelin La 22.5Mg Inj is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Inform your doctor if you have any allergic reactions to Pamorelin La 22.5Mg Inj or other medications. Before starting Pamorelin La 22.5Mg Inj, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Pamorelin La 22.5Mg Inj may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Pamorelin La 22.5Mg Inj. Pamorelin La 22.5Mg Inj can affect the unborn baby when used in pregnancy. Hence, Pamorelin La 22.5Mg Inj is not indicated for use in pregnancy and breastfeeding women. If you are using Pamorelin La 22.5Mg Inj, make sure to use reliable forms of contraception to prevent pregnancy during the course. Pamorelin La 22.5Mg Inj may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Pamorelin La 22.5Mg Inj can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Pamorelin La 22.5Mg Inj is not recommended for children younger than two years of age.

Drug-Drug Interactions

verifiedApollotooltip
TriptorelinClozapine
Severe
TriptorelinCeritinib
Severe

Drug-Drug Interactions

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TriptorelinClozapine
Severe
How does the drug interact with Pamorelin La 22.5Mg Inj:
Combining Pamorelin La 22.5Mg Inj with Clozapine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Pamorelin La 22.5Mg Inj and Clozapine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like an irregular heart rhythm, dizziness, shortness of breath, or heart palpitations, it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
TriptorelinCeritinib
Severe
How does the drug interact with Pamorelin La 22.5Mg Inj:
Coadministration of Pamorelin La 22.5Mg Inj with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Ceritinib with Pamorelin La 22.5Mg Inj can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
TriptorelinMoxifloxacin
Severe
How does the drug interact with Pamorelin La 22.5Mg Inj:
Using moxifloxacin together with Pamorelin La 22.5Mg Inj can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Pamorelin La 22.5Mg Inj together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like an irregular heart rhythm, prolonged diarrhea or vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, you should contact your doctor right away. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. 
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

Habit Forming

No

Therapeutic Class

GONADOTROPHIN-RELEASING HORMONE AGONIST

All Substitutes & Brand Comparisons

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Alcohol

Caution

It is advised to avoid alcohol consumption to minimize the unwanted effects of Pamorelin La 22.5Mg Inj. Please consult your doctor for more information.

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Pregnancy

Unsafe

Pamorelin La 22.5Mg Inj is a pregnancy category X drug. It is unsafe to use Pamorelin La 22.5Mg Inj in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using Pamorelin La 22.5Mg Inj.

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Breast Feeding

Unsafe

Pamorelin La 22.5Mg Inj is unsafe to use during breastfeeding. Consult your doctor for further information.

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Driving

Unsafe

Pamorelin La 22.5Mg Inj causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Pamorelin La 22.5Mg Inj.

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment before starting Pamorelin La 22.5Mg Inj.

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Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting Pamorelin La 22.5Mg Inj.

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Children

Caution

Pamorelin La 22.5Mg Inj is not recommended in children younger than two years of age.

FAQs

Pamorelin La 22.5Mg Inj is used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children.

Pamorelin La 22.5Mg Inj contains Triptorelin, a synthetic hormone. It helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis in women.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Pamorelin La 22.5Mg Inj should be used with caution and under doctor's supervision only if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Let your doctor know if you have any other medical concerns before using Pamorelin La 22.5Mg Inj.

During treatment with Pamorelin La 22.5Mg Inj in the first few weeks, a temporary increase in hormones may occur before they decrease. This may cause new or worsening of side effects of Pamorelin La 22.5Mg Inj. This is a normal response of your body to Pamorelin La 22.5Mg Inj. However, if you notice any symptoms that are not manageable, please seek medical advice.

Pamorelin La 22.5Mg Inj may worsen your mood disorders like depression. Hence it is advised to use Pamorelin La 22.5Mg Inj only when you are free from any kind of mental problems. Please consult your doctor for more information.

Pamorelin La 22.5Mg Inj may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting Pamorelin La 22.5Mg Inj.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - PAM0270

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 10, 2025 | 3:14 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.webmd.com/drugs/2/drug-22363-9162/triptorelin-pamoate-intramuscular/triptorelin-1-month-3-75-mg-injection/details
  2. https://www.medicines.org.uk/emc/files/pil.780.pdf
  3. https://www.drugs.com/mtm/triptorelin.html#uses

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