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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Panpraz-D Capsule is used to treat peptic ulcers and gastroesophageal reflux disease (GERD). It prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn. It contains Domperidone and Pantoprazole, which work by increasing the movement of food through the stomach and the digestive tract more quickly. This helps reduce the feeling of bloating, or fullness and indigestion. It helps in reducing the stomach acid. Also, it effectively blocks the action of vomiting centre in your brain, that is responsible for inducing the feeling of nausea and vomiting.

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Manufacturer/Marketer :

Citric Labs

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Panpraz-D Capsule

Panpraz-D Capsule is composed of two medicines, Domperidone and Pantoprazole. Domperidone is a prokinetic and anti-nausea agent that helps to treat indigestion and stomach pain. On the other hand, Pantoprazole is a proton pump inhibitor that reduces excess stomach acid formation by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). Panpraz-D Capsule is a widely used medicine to treat peptic ulcers and gastroesophageal reflux disease (GERD). Panpraz-D Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and, in this way, reduces the feeling of bloating, fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall and is responsible for the release of gastric acid secretion, damaging tissues in the food pipe, stomach, and duodenum.

It should be taken as prescribed by the doctor. Like all medicines, Panpraz-D Capsule may cause side effects, although not everybody gets them. The most common side effects of Panpraz-D Capsule are diarrhoea, stomach pain, flatulence (gas), dryness in the mouth, dizziness, and headache. Everyone doesn't need to experience the above side effects. In case of any discomfort, speak with your doctor.

It is recommended not to use it if you are allergic to any of its ingredients. Prolonged intake of Pantoprazole is associated with a low level of Vitamin B12 and low magnesium. Hence, a yearly test of Vitamin B12 and magnesium is required if you are taking Panpraz-D Capsule for the long term. Use of Panpraz-D Capsule is contraindicated in people with lupus (autoimmune inflammatory disease). Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Uses of Panpraz-D Capsule

Panpraz-D Capsule is used in the treatment of Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of the food pipe (esophagitis), and Peptic ulcers.The detailed uses of Panpraz-D Capsule are as follows:
•Gastroesophageal Reflux Disease (GERD): Panpraz-D Capsule is commonly used to alleviate GERD symptoms and lower stomach acid production by relieving heartburn and acid reflux.
•Peptic Ulcers: Panpraz-D Capsule is useful in treating peptic ulcers, assisting in healing and minimizing ulcer recurrence by regulating gastric acid output.
•Dyspepsia: Panpraz-D Capsule is usually given to treat dyspeptic symptoms such as bloating, nausea, and discomfort by improving stomach motility and decreasing acid output.
•Zollinger-Ellison Syndrome: Panpraz-D Capsule is used to treat Zollinger-Ellison syndrome, a disorder marked by increased stomach acid production, and it aids in reducing the symptoms and problems associated with the condition.
•Inflammation of the food pipe (esophagitis): Panpraz-D Capsule is also involved in treating esophagitis and works by blocking the gastric proton pump to relieve symptoms and promote healing.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Panpraz-D Capsule plays a vital role in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions due to hyperacidity or acid reflux. Pantoprazole prevents the proton pump gate from producing an excessive amount of stomach acid. While Domperidone stops nausea (feeling sick) and vomiting (being sick), it blocks messages between parts of your brain called the chemoreceptor trigger zone (CTZ) and the vomiting centre.

How Panpraz-D Capsule Works

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and, in this way, reduces the feeling of bloating, fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall and is responsible for the release of gastric acid secretion, damaging tissues in the food pipe, stomach, and duodenum.
Side effects of Panpraz-D Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Panpraz-D Capsule

Do not take more than the prescribed dose of Panpraz-D Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Panpraz-D Capsule if you are allergic to Panpraz-D Capsule or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Panpraz-D Capsule may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Panpraz-D Capsule may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Panpraz-D Capsule may mask the symptoms of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool), immediately consult the doctor.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
PantoprazoleMethotrexate
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Panpraz-D Capsule:
Co-administration of Rilpivirine is taken with Panpraz-D Capsule, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Panpraz-D Capsule with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PantoprazoleMethotrexate
Severe
How does the drug interact with Panpraz-D Capsule:
Co-administration of Methotrexate with Panpraz-D Capsule can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Panpraz-D Capsule and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
PantoprazoleDacomitinib
Severe
How does the drug interact with Panpraz-D Capsule:
Taking Panpraz-D Capsule can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Panpraz-D Capsule with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleNelfinavir
Severe
How does the drug interact with Panpraz-D Capsule:
Taking Nelfinavir with Panpraz-D Capsule may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Panpraz-D Capsule with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleDasatinib
Severe
How does the drug interact with Panpraz-D Capsule:
Taking Dasatinib with Panpraz-D Capsule may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Panpraz-D Capsule with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
PantoprazoleErlotinib
Severe
How does the drug interact with Panpraz-D Capsule:
Taking Erlotinib with Panpraz-D Capsule may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Panpraz-D Capsule with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazolePazopanib
Severe
How does the drug interact with Panpraz-D Capsule:
Taking Panpraz-D Capsule with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Panpraz-D Capsule and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PantoprazoleGefitinib
Severe
How does the drug interact with Panpraz-D Capsule:
Taking Gefitinib with Panpraz-D Capsule reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Panpraz-D Capsule with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Panpraz-D Capsule to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
PantoprazoleAtazanavir
Severe
How does the drug interact with Panpraz-D Capsule:
Co-administration of Panpraz-D Capsule reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Panpraz-D Capsule with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), which prevents the backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Panpraz-D Capsule Substitute

Substitutes safety advice
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  • Piza-D Tablet 10's

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    8.01per tablet
  • Panido-D Tablet 15's

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    11.55per tablet
  • Geripan D Tablet 10's

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    7.92per tablet
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Alcohol

Caution

It is best to avoid alcohol while taking medication.

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Pregnancy

Caution

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. You should use this medicine only if your doctor considers the benefit for you greater than the potential risk for your unborn child or baby.

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Breast Feeding

Caution

Panpraz-D Capsule should be used in breastfeeding mothers only if the benefits outweigh the risks.

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Driving

Caution

Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking Panpraz-D Capsule you should not drive or operate any machinery or vehicles.

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Liver

Caution

In patients with severe liver impairment, the liver enzymes should be monitored regularly during treatment with pantoprazole, particularly on long-term use

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Kidney

Caution

Inform your doctor before receiving the Panpraz-D Capsule if you have a kidney impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Panpraz-D Capsule can be given safely to children provided; dose has been prescribed by a child specialist.

Have a query?

FAQs

Panpraz-D Capsule is used to treat Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), and Peptic ulcer.

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and, in this way, reduces the feeling of bloating, fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall and is responsible for the release of gastric acid secretion, damaging tissues in the food pipe, stomach, and duodenum.

Panpraz-D Capsule can be safely taken as long as your doctor has prescribed it to you.

Yes, taking Panpraz-D Capsule for a very long time can cause calcium depletion in the body, leading to weakening of bones. Hence, a calcium and vitamin D supplement is recommended along with Panpraz-D Capsule to replenish calcium depletion in the body.

Yes. Panpraz-D Capsule can alter certain medical tests, such as those for neuroendocrine tumours (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such diagnostic tests, contact your doctor.

Prolonged intake of Panpraz-D Capsule may weaken your bone and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 to enhance haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

A combination of pantoprazole and domperidone is effective and safe.

No, Panpraz-D Capsule is a prescribed drug with minimal side effects. Only take it if your doctor has recommended it to you for acidity.

Panpraz-D Capsule is an antacid medicine containing Domperidone (anti-emetic) and Pantoprazole (proton pump inhibitor). It is used to treat acidity-related conditions.

Yes, Panpraz-D Capsule is safe for use if taken in the dose and duration prescribed by the doctor.

Do not take Panpraz-D Capsule if you are allergic to any of its components. It should be used with caution in patients with liver or kidney disease.

Dry mouth could be a side-effect of Panpraz-D Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Panpraz-D Capsule may cause diarrhoea as a side effect. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. Consult the doctor if the diarrhoea persists or worsens.

Store Panpraz-D Capsule at room temperature, in a dry place. Keep out of sight and reach of children.

Foods/drinks that aggravate acidity like fried or spicy food, butter, oil, beverages containing caffeine, citrus fruits and alcohol should be avoided.

Alcohol may not affect Panpraz-D Capsule . However, it might increase acid production. Therefore, avoid alcohol consumption.

Do not discontinue Panpraz-D Capsule without consulting your doctor. To treat your condition effectively, keep taking Panpraz-D Capsule for the prescribed duration.

Country of origin

India

Manufacturer/Marketer address

Plot-121, Second Floor, Phase-1, Industrial area, Panchkula-134113
Other Info - PAN1569

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