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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Paxilyf CR 25 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. It contains Paroxetine which works by increasing serotonin concentration, thereby regulating mood. This medicine may sometimes cause side effects such as insomnia, dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

PAROXETINE-25MG

Manufacturer/Marketer :

Lyf Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Paxilyf CR 25 Tablet

Paxilyf CR 25 Tablet belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoria disorder and generalised anxiety disorder. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.

Paxilyf CR 25 Tablet contains ‘Paroxetine’, which is a selective serotonin reuptake inhibitor. It works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.

Take Paxilyf CR 25 Tablet as prescribed. You are advised to take Paxilyf CR 25 Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and sexual disturbances. You are advised to talk to your doctor if the side effects persist or worsen.

Do not take Paxilyf CR 25 Tablet if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Paxilyf CR 25 Tablet if you are breastfeeding. Avoid driving or operating machinery as Paxilyf CR 25 Tablet may cause dizziness, confusion, sleepiness and blurred vision. Paxilyf CR 25 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Paxilyf CR 25 Tablet as it may make your symptoms or side-effects worse. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Paxilyf CR 25 Tablet

Treatment of Major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Directions for Use

Take Paxilyf CR 25 Tablet in the morning with food to prevent stomach upset. Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.

Medicinal Benefits

Paxilyf CR 25 Tablet belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Paxilyf CR 25 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. Paxilyf CR 25 Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders. Paxilyf CR 25 Tablet has fewer unwanted side effects than older antidepressants and helps people recover from depression.

How Paxilyf CR 25 Tablet Works

Paxilyf CR 25 Tablet contains ‘Paroxetine’, which is a selective serotonin reuptake inhibitor. It works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.

Storage

Store in a cool and dry place away from sunlight
Side effects of Paxilyf CR 25 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Quit smoking as smoking impairs erectile function by significantly damaging blood vessels.
  • Maintain a healthy weight as overweight can cause erectile dysfunction.
  • Exercise regularly as physical activity enhances blood flow and overall health, benefiting erectile function.
  • Consume a healthy diet loaded with whole grains, fruits and vegetables.
  • Limit alcohol consumption as excessive alcohol intake can impair erectile function.
  • Manage stress by practicing techniques such as yoga, relaxation exercises or meditation.
  • In case erectile dysfunction is due to psychological factors, consider couple counselling or sex therapy to address relationship and anxiety issues.
  • Openly discuss your concerns with your partner.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.

What if I have taken an overdose of Paxilyf CR 25 Tablet

Take Paxilyf CR 25 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sleepiness, nausea, vomiting, tremors, dizziness, confusion, fast heart rate, and coma. Other symptoms observed with the overdose are dilation of the pupil, convulsions, irregular heartbeat, high/low blood pressure, aggressive reactions, liver dysfunction, state of unconsciousness, involuntary muscle contractions, rhabdomyolysis (breakdown of muscle tissue), manic reactions, acute kidney failure, urinary retention, and serotonin syndrome. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Paxilyf CR 25 Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days, or if you are taking antipsychotic medicines such as thioridazine or pimozide. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, diabetes, low sodium levels in blood, glaucoma, or are undergoing treatment for severe depression called electro-convulsive therapy. Do not take Paxilyf CR 25 Tablet if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Paxilyf CR 25 Tablet if you are breastfeeding. Avoid driving or operating machinery as Paxilyf CR 25 Tablet may cause dizziness, confusion, sleepiness and blurred vision. Paxilyf CR 25 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Paxilyf CR 25 Tablet as it may make your symptoms or side-effects worse.

Drug-Drug Interactions

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ParoxetineIsocarboxazid
Critical

Drug-Drug Interactions

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How does the drug interact with Paxilyf CR 25 Tablet:
Taking Furazolidone with Paxilyf CR 25 Tablet can increase the risk of side effects

How to manage the interaction:
Taking Paxilyf CR 25 Tablet with Furazolidone is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineIsocarboxazid
Critical
How does the drug interact with Paxilyf CR 25 Tablet:
Using isocarboxazid with Paxilyf CR 25 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paxilyf CR 25 Tablet with Isocarboxazid is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Paxilyf CR 25 Tablet:
When Paxilyf CR 25 Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Paxilyf CR 25 Tablet with Selegiline can possibly lead to an interaction but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Paxilyf CR 25 Tablet:
Using Metoclopramide with Paxilyf CR 25 Tablet can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Metoclopramide with Paxilyf CR 25 Tablet is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Paxilyf CR 25 Tablet:
Using Linezolid together with Paxilyf CR 25 Tablet can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Taking Paxilyf CR 25 Tablet with Linezolid is not recommended but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetinePhenelzine
Critical
How does the drug interact with Paxilyf CR 25 Tablet:
Using phenelzine with Paxilyf CR 25 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paxilyf CR 25 Tablet with Phenelzine is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Paxilyf CR 25 Tablet:
Using tranylcypromine with Paxilyf CR 25 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paxilyf CR 25 Tablet with Tranylcypromine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Paxilyf CR 25 Tablet:
Combining Paxilyf CR 25 Tablet with Pimozide can effect the rhythm of the heart

How to manage the interaction:
Taking Paxilyf CR 25 Tablet with Pimozide is not recommended, but should be taken if advised by a doctor. However, if you experience chest tightness, irregular heartbeat, blurred vision and nausea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Paxilyf CR 25 Tablet:
Coadministration of Paxilyf CR 25 Tablet with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine with Paxilyf CR 25 Tablet is not recommended, but should be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineEliglustat
Critical
How does the drug interact with Paxilyf CR 25 Tablet:
Coadministration of Paxilyf CR 25 Tablet with eliglustat can increase the risk of irregular heart rhythm

How to manage the interaction:
Although there is an interaction between Paxilyf CR 25 Tablet and Eliglustat, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Paxilyf CR 25 Tablet as it may make your symptoms or side-effects worse.

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Pregnancy

Unsafe

Paxilyf CR 25 Tablet belongs to pregnancy category D. It is not recommended to take Paxilyf CR 25 Tablet if you are pregnant or planning for pregnancy as Paxilyf CR 25 Tablet might cause foetal harm.

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Breast Feeding

Caution

Paxilyf CR 25 Tablet may pass into breastmilk. Consult your doctor before taking Paxilyf CR 25 Tablet ; your doctor will decide whether Paxilyf CR 25 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Avoid driving or operating machinery as Paxilyf CR 25 Tablet may cause dizziness, confusion, sleepiness and blurred vision.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Paxilyf CR 25 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

Have a query?

FAQs

Paxilyf CR 25 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Paxilyf CR 25 Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This increases serotonin concentrations in the nerve synapse, thereby helping in regulating mood.

Do not discontinue Paxilyf CR 25 Tablet without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually, continue taking Paxilyf CR 25 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Paxilyf CR 25 Tablet ; the doctor may reduce the dose gradually.

Paxilyf CR 25 Tablet may cause decreased libido (sex drive), impotence (erectile dysfunction), abnormal ejaculation and problems with orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth could be a side-effect of Paxilyf CR 25 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Please consult your doctor before taking Paxilyf CR 25 Tablet if you have glaucoma as Paxilyf CR 25 Tablet might cause increased pressure in the eye.

Consult your doctor before taking Paxilyf CR 25 Tablet if you have diabetes as Paxilyf CR 25 Tablet might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Paxilyf CR 25 Tablet . Talk to your doctor if your blood sugar levels are unstable.

People taking antidepressants such as Paxilyf CR 25 Tablet are more likely at risk of developing suicidal thoughts. Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Consult your doctor before taking tamoxifen (used to treat cancer) along with Paxilyf CR 25 Tablet as Paxilyf CR 25 Tablet might make tamoxifen less effective.

Paxilyf CR 25 Tablet may cause unusual bleeding or bruising such as vomiting blood or passing blood in stools. Therefore, talk to your doctor before taking Paxilyf CR 25 Tablet if you have a history of bleeding disorders or if you are taking medicines that might increase the risk of bleeding such as blood thinners (warfarin), anti-psychotics (perphenazine or clozapine), tricyclic antidepressants (clomipramine), or NSAID’s (acetylsalicylic acid, ibuprofen, celecoxib, etodolac, diclofenac, meloxicam).

Paxilyf CR 25 Tablet may cause side effects such as nausea, headache, diarrhoea, dry mouth, fatigue (overtiredness), loss of appetite and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.

Yes, bone fractures have been associated with Paxilyf CR 25 Tablet .

The risk of serotonin syndrome is increased when Paxilyf CR 25 Tablet is taken together with other serotonergic medicines, including tricyclic antidepressants, fentanyl, triptans, tramadol, buspirone, lithium, tryptophan, thioridazine, isocarboxazid, pimozide, intravenous methylene blue, linezolid, amphetamines, procarbazine, phenelzine, selegiline, tranylcypromine and St. John’s Wort.

You may start noticing an improvement in your symptoms after 1-2 weeks of starting the treatment with Paxilyf CR 25 Tablet . If you do not see any improvement, do not stop taking Paxilyf CR 25 Tablet and consult your doctor. It may take around 4-6 weeks to see the full effects of Paxilyf CR 25 Tablet .

No, do not stop taking Paxilyf CR 25 Tablet suddenly, without first consulting your doctor. This is a common problem with Paxilyf CR 25 Tablet that you may feel your symptoms have worsened initially but the benefits start showing after 1-2 weeks. You must consult your doctor if the worsening does not improve even after 1-2 weeks.

Paxilyf CR 25 Tablet is not recommended for children and adolescents below 18 years of age as patients in this age group have an increased risk of experiencing side effects such as aggression, suicidal thoughts, oppositional behavior and anger when they take Paxilyf CR 25 Tablet . If you have any concerns regarding this, please discuss with your doctor.

No, do not take Paxilyf CR 25 Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Paxilyf CR 25 Tablet . However, Paxilyf CR 25 Tablet may make tamoxifen less effective and can lead to recurrence of breast cancer.

Yes, you need to be careful while taking Paxilyf CR 25 Tablet if you are a diabetic as Paxilyf CR 25 Tablet may change your blood sugar levels. Thus, may need dose adjustment of your insulin or antidiabetic medicines. Discuss with your doctor regarding this and monitor your blood sugar levels regularly.

Paxilyf CR 25 Tablet is usually considered safe if taken as advised by a doctor. However, it may cause side effects, just like any medication. Discuss with your doctor about your concerns or potential risks before starting Paxilyf CR 25 Tablet .

No, Paxilyf CR 25 Tablet is not a sleeping pill. Although its calming effect can promote better sleep, its main purpose is to manage depression and anxiety symptoms.

Your doctor determines the best time to take Paxilyf CR 25 Tablet . It can be taken with or without food, but follow your doctor's instructions for dosage and timing.

It may take a few weeks for Paxilyf CR 25 Tablet to show improvements in your symptoms. Even if you do not see immediate results, it is important to keep taking it as prescribed by your doctor.

Yes, Paxilyf CR 25 Tablet helps manage various anxiety disorders such as obsessive-compulsive disorder and panic disorder. It helps reduce anxiety symptoms by restoring the balance of serotonin in the brain.

If you experience any side effects while taking Paxilyf CR 25 Tablet , inform your doctor immediately. After analysing your symptoms, they will modify your treatment plan.

Country of origin

India
Other Info - PAX0091

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