apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Pentabloc 40 Capsule

Pentabloc 40 Capsule, Pack of 1 Capsule
Offers on medicine orders
All offers
axis icici
Written By Lakshmithulasi Yarragunta ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Pentabloc 40 Capsule is used to treat gastroesophageal reflux disease (GERD), stomach ulcer, Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour), duodenal ulcer, gastric ulcer and Crohn's Disease-associated Ulcers. It contains Pantoprazole, which reduces the amount of acid your stomach makes. It prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn. It may cause common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Read more
rxMedicinePrescription drug

Whats That

tooltip

Also Explore

Momverse
Ask Apollo
insurance

Composition :

PANTOPRAZOLE-40MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Pentabloc 40 Capsule

Pentabloc 40 Capsule belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Pentabloc 40 Capsule helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus prevents the release of stomach acid and relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Not everyone who is taking Pentabloc 40 Capsule will get these side effects. Pentabloc 40 Capsule may have common side effects, such as headache, diarrhoea, nausea, abdominal pain, vomiting, dizziness, and joint pain. These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Take Pentabloc 40 Capsule as advised. Your physician will decide the dosage based on your medical condition. You should take Pentabloc 40 Capsule 30 minutes before food. It is recommended not to exceed the recommended dose of Pentabloc 40 Capsule. Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to Pentabloc 40 Capsule. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Pentabloc 40 Capsule or will have an endoscopy in the future. Prolonged intake of Pentabloc 40 Capsule may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium and Vitamin D, leading to osteoporosis. Pentabloc 40 Capsule is not recommended for children below 5 years of age. Consult the doctor if you are pregnant or breastfeeding.

Uses of Pentabloc 40 Capsule

Pentabloc 40 Capsule is used to treat peptic ulcers, heartburn, and hyperacidity. The following are the specific applications of Pentabloc 40 Capsule:

  • Gastric reflux disease (GERD): Pentabloc 40 Capsule is frequently used to treat GERD by decreasing the production of stomach acid, which lessens the symptoms of acid reflux and heartburn.
  • Erosive Esophagitis: This medication efficiently promotes healing and symptom relief for this ailment, which is brought on by inflammation and damage to the oesophagus as a result of acid reflux.
  • Peptic Ulcers: By lowering stomach acid, Pentabloc 40 Capsule can be used to treat peptic ulcers and promote the healing of the affected areas.
  • Zollinger-Ellison Syndrome: This uncommon ailment results in an overabundance of stomach acid. Pentabloc 40 Capsule considerably lowers acid secretion, which aids with symptom management.

Directions for Use

  • Pentabloc 40 Capsule should be taken 30-60 minutes before a meal to enhance absorption and effectiveness.
  • It is usually taken once daily in the morning or as advised by your doctor. If prescribed twice daily, take the second dose before dinner.
  • Swallow Pentabloc 40 Capsule as a whole with a glass of water.
  • Do not crush, chew, open, or break it.

Medicinal Benefits

  • Pentabloc 40 Capsule is effective in healing erosive esophagitis (inflammation of the food pipe), heartburn, Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers. 
  • Pentabloc 40 Capsule works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • Pentabloc 40 Capsule helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How Pentabloc 40 Capsule Works

Pentabloc 40 Capsule contains pantoprazole as an active ingredient. It helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase) that is located in the cells of the stomach wall and is responsible for releasing gastric acid, which can damage tissues in the food pipe, stomach, and duodenum. Pentabloc 40 Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Pentabloc 40 Capsule

Do not take more than the prescribed dose of Pentabloc 40 Capsule as it may cause gastic irritation, trouble breathing or passing out. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Pentabloc 40 Capsule if you are allergic to Pentabloc 40 Capsule or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1. 
  • Prolonged intake of Pentabloc 40 Capsule may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), vitamin B12, and magnesium deficiency. 
  • Pentabloc 40 Capsule may interact with blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications. Please inform your doctor if you are taking any of these medications. 
  • Intake of Pentabloc 40 Capsule may mask the symptoms of gastric cancer, so if you have any severe stomach pain or blood in stool, immediately consult the doctor.
  • This medicine is not recommended for use in children below 5 years of age. 
  • Although Pentabloc 40 Capsule is safe for use during pregnancy or breastfeeding, inform your doctor if you are pregnant or breastfeeding before starting treatment with Pentabloc 40 Capsule. 
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products, to prevent any interactions.
  • It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

Diet & Lifestyle Advise

  • Avoid consuming foods or drinks that trigger acid reflux or heartburn, such as onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat foods, and spicy foods.
  • Before going to sleep, raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will prevent stomach acid from backing up into your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing the backflow of the stomach acid into the food pipe.
  • Include high-fibre-containing foods, such as berries, cherries, leafy green veggies (like kale and spinach), and black pepper in your meal. These foods are rich in antioxidants, calcium, and vitamin B12, which can help mitigate the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H. pylori infection.
  • Avoid sitting for long periods, as it can increase stomach acid production. Try to take a 5-minute break every hour by going for a brisk walk or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Pentabloc 40 Capsule Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Drinking alcohol with Pentabloc 40 Capsule may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Pentabloc 40 Capsule.

bannner image

Pregnancy

Consult your doctor

Pentabloc 40 Capsule is safe for use in pregnant women. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

bannner image

Breast Feeding

Consult your doctor

Pentabloc 40 Capsule is safe for use in lactating mothers. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

bannner image

Driving

Caution

In some cases, Pentabloc 40 Capsule may cause dizziness, sleepiness, or blur vision. If you observe these symptoms, do not drive or operate heavy machinery until you feel better.

bannner image

Liver

Caution

Pentabloc 40 Capsule should be taken with caution if you have liver problems.

bannner image

Kidney

Consult your doctor

Patients with kidney disease should consult a doctor before taking Pentabloc 40 Capsule.

bannner image

Children

Caution

Pentabloc 40 Capsule is not be prescribed for children under 5 years of age. It is generally prescribed from 5-16 years of children for the treatment of gastroesophageal reflux disease (GERD).

Have a query?

FAQs

Pentabloc 40 Capsule is used to treat Hyperacidity, Heartburn, and Peptic ulcer.

Pentabloc 40 Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

No. Gas and acidity are two different common discomforts. Acidity is caused when the improper functioning of the valve (sphincter) is located at the junction of the stomach and the food pipe. As a result, stomach acid backs up and enters the upper part of the oesophagus, causing heartburn. On the other hand, gas is a byproduct of digestion, eliminating gases like carbon dioxide, hydrogen, nitrogen, and methane from the body.

Yes. Pentabloc 40 Capsule can alter specific medical tests, such as neuroendocrine tumour (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such tests, contact your doctor.

Prolonged intake of Pentabloc 40 Capsule may weaken your bone and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

No. Pentabloc 40 Capsule prevents the excessive production of stomach acid, which can cause acid reflux and heartburn. If blood is present in your stool or mucus, contact your doctor immediately.

Prolonged intake of Pentabloc 40 Capsule may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin-enhancing medications to cope with long-term side effects.

No. Pentabloc 40 Capsule is not prescribed for stomach cancer. Do not take Pentabloc 40 Capsule until your doctor has prescribed it to you. Pentabloc 40 Capsule is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.

You should start to feel better in 2-3 days of starting Pentabloc 40 Capsule. However, it might take up to 4 weeks for Pentabloc 40 Capsule to work properly. Consult a doctor if you don't feel better or if your condition doesn't improve.

A single dose of Pentabloc 40 Capsule may not be sufficient. To treat your condition properly, take Pentabloc 40 Capsule in the dose and for the duration prescribed by your doctor.

Yes, it is safe to take Pentabloc 40 Capsule if your doctor prescribes it. It is a well-tolerated medicine.

Pentabloc 40 Capsule is usually prescribed for a short term. However, in some cases, it may be indicated in the long-term management of reflux oesophagitis. If you take Pentabloc 40 Capsule on a long-term basis (longer than 1 year), your doctor will advise regular monitoring.

It is best to take Pentabloc 40 Capsule 30 minutes to one hour before a meal.

Pentabloc 40 Capsule should not be discontinued without a doctor’s consultation. To treat your condition effectively, take Pentabloc 40 Capsule for as long as it has been prescribed. Talk to the doctor if you have any concerns.

Pentabloc 40 Capsule may cause weight changes as a side effect. Consult the doctor if you notice any weight changes that bother you.

Avoid alcohol consumption as it might make your stomach produce more acid than usual. This can irritate the stomach lining and make your symptoms worse.

Antacids can be taken with Pentabloc 40 Capsule if prescribed by the doctor. However, maintain a 2-hour gap between Pentabloc 40 Capsule and antacid medicines.

Eat smaller and more frequent meals. Avoid foods that trigger acidity, such as fatty and fried foods, spicy foods, carbonated drinks, and alcohol. Include non-citrus fruits, vegetables, lean meat, oatmeal, whole-grain bread, and rice in your diet. Do not lie down immediately after eating, and avoid vigorous exercise for at least a couple of hours afterwards.

Yes, it is safe to take painkillers along with Pentabloc 40 Capsule if advised by the doctor. To prevent stomach upset, painkillers can be taken with or just after a meal.

Pentabloc 40 Capsule should be swallowed as a whole with water; do not crush, break or chew it. Pentabloc 40 Capsule should be taken 30-60 minutes before meal.

Take the missed dose as soon as you remember, unless it is time for the scheduled dose. Do not take a double dose to make up for the forgotten dose. Take your next regular dose at the usual time.

In some people, Pentabloc 40 Capsule may cause side effects such as headaches, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Most of these side effects are temporary and usually resolve over time. However, if any side effects persist or worsen, contact your doctor.

Other Info - PENT421

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Praneetha AkunuriDoctor badge

Reviewed By

Praneetha Akunuri

M.Pharmacy

Last Updated

Aug 5, 2025 | 12:55 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/tips/pantoprazole-patient-tips
  2. https://www.nhs.uk/medicines/pantoprazole/
  3. https://www.medicines.org.uk/emc/product/484/pil#gref
  4. https://www.drugs.com/pro/pantoprazole-granules.html#s-34068-7
  5. https://mms.mckesson.com/product/1002689/Pfizer-00008084402
whatsapp Floating Button