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compositionComposition:ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MG
prescription
Prescription Medicine
info
Planit Tablet 21's

Planit Tablet 21's is used for contraception and treating dysmenorrhea (irregular and painful periods). It contains Ethinylestradiol and Levonorgestrel, which maintains a normal menstrual cycle (periods) in women. It works by fulfilling the deficiency of estrogen hormone, thereby preventing symptoms like night sweats, hot flashes, and mood swings. Also, it prevents the release of an egg from the ovary (female reproductive cells) or prevents fertilization of an egg by sperm (male reproductive cells). It may also change the lining of the uterus to prevent the development of a pregnancy. It may cause side effects such as stomach pain, headache, nausea, breast pain, weight gain, and irregular uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MG

Manufacturer/Marketer :

Biological E Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Planit Tablet 21's

Planit Tablet 21's is an oral prescription medication primarily used to prevent pregnancy. It is a combined hormonal pill that helps women manage family planning reliably. Additionally, healthcare providers may prescribe it to regulate menstrual cycles and manage heavy or painful periods.

For maximum effectiveness, you must take this tablet once daily at the exact same time every day without fail. You can take it with or without food, though taking it with your evening meal or at bedtime may help reduce mild stomach upset. Maintaining a consistent routine is crucial to ensuring its protective effects.

While taking Planit Tablet 21's, you may notice mild side effects like temporary nausea, breast tenderness, or light spotting between your periods. These usually resolve as your body adjusts to the hormones. However, you should contact your doctor immediately if you experience severe symptoms, such as sudden chest pain, severe headaches, or swelling and warmth in one of your legs.

Do not take this if you have a history of blood clots, active liver damage, uncontrolled high blood pressure, or breast cancer. It is also not recommended for women over the age of 35 who smoke, as this combination greatly increases the risk of serious cardiovascular complications. Talk to your doctor to ensure this option is safe for your specific medical history.

Certain medications, including some anti-seizure drugs and specific antibiotics, can make Planit Tablet 21's less effective, increasing the risk of unexpected pregnancy. Avoid smoking while using this treatment, as it raises your risk of heart problems and blood clots. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before starting this treatment.

Uses of Planit Tablet 21's

Planit Tablet 21's is used to treat contraception and dysmenorrhea (irregular menstrual periods). The detailed uses of Planit Tablet 21's are as follows:

  • Pregnancy Prevention (Contraception): Planit Tablet 21's is highly effective at preventing unwanted pregnancy by stopping the release of an egg from the ovaries, thickening cervical mucus to block sperm, and altering the womb lining.
  • Irregular Menstrual Cycles: This medication regulates your hormone levels, helping to establish a highly predictable and consistent monthly period cycle.
  • Painful or Heavy Periods: Planit Tablet 21's lightens blood flow and reduces painful uterine cramping, making your monthly cycles much more manageable.

Key Benefits

Planit Tablet 21's helps provide reliable contraception while supporting better menstrual cycle control and reproductive health. Regulating hormone levels can help improve menstrual symptoms and offer greater predictability in your monthly cycle. Benefits may include:

• Provides effective and reliable pregnancy prevention when used as directed.
• Helps regulate menstrual cycles and improve cycle predictability.
• Reduces menstrual cramps and discomfort during periods.
• Helps decrease heavy menstrual bleeding and associated symptoms.
• May improve acne and other hormone-related skin concerns in some women.
• May help manage symptoms associated with conditions such as endometriosis and provide certain long-term reproductive health benefits.
 

Directions for Use

  • Swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet.
  • Take one tablet every day at the exact same time. Setting a daily alarm on your phone can help you stay consistent.
  • You can take this medication with or without food. If you experience mild nausea, taking it after your evening meal or right before bed may help.
  • Follow the arrows and days printed on the blister pack to keep track of your daily doses.

How Planit Tablet 21's Works

Planit Tablet 21's contains Ethinylestradiol and Levonorgestrel. • Ethinylestradiol: It helps prevent pregnancy by stopping the release of an egg from the ovaries. It also helps regulate the menstrual cycle and reduce irregular bleeding. • Levonorgestrel: It helps prevent pregnancy by thickening the fluid at the entrance of the womb, making it difficult for sperm to reach an egg. It also helps make the lining of the womb less suitable for implantation.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Planit Tablet 21's to avoid unpleasant side effects.

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Pregnancy

Unsafe

Caution should be exercised. Hormonal medicines can affect the developing baby. It is advisable to consult a doctor before using it.

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Breast Feeding

Unsafe

Not safe; this Planit Tablet 21's may pass into breast milk. They may harm the baby and also may affect the production of milk. So, this Planit Tablet 21's is unsafe for breastfeeding mothers.

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Driving

Caution

Planit Tablet 21's has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Planit Tablet 21's to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Planit Tablet 21's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Planit Tablet 21's is not recommended for children. Safety and efficacy of Planit Tablet 21's are established in women of reproductive age. But sufficient studies have not been performed on women less than 16 years of age. So, take Planit Tablet 21's only when prescribed by a doctor.

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Heart

Unsafe

Planit Tablet 21's is not recommended for use in heart patients as it can lead to side effects like heart attack, blood clots, or stroke in some patients.

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Geriatrics

Unsafe

Planit Tablet 21's is not recommended for use in elderly patients and postmenopausal women.

What if I have taken an overdose of Planit Tablet 21's

If you accidentally take more than your prescribed dose, seek emergency medical care immediately. While an overdose of this medication is unlikely to be life-threatening, it can cause symptoms such as severe nausea, vomiting, or unexpected vaginal bleeding. Contact a healthcare provider or your local poison control center right away.

Diet & Lifestyle Advise

  • Do not smoke: Smoking significantly increases your risk of serious cardiovascular complications, including blood clots, heart attacks, and strokes, especially if you are over 35.
  • Stay active on long journeys: If you are traveling for more than four hours, make sure to stretch your legs, walk around, or perform simple foot exercises to keep blood circulating and prevent blood clots.
  • Monitor your blood pressure: This medication can sometimes raise blood pressure. Check your blood pressure regularly at home or during routine doctor visits.
  • Limit alcohol intake: Excessive drinking can place extra strain on your liver, which is responsible for processing this medication.
  • Maintain a balanced diet: Eating foods rich in calcium and vitamin D can help support bone health, which is important for overall hormonal wellness.
     

Have a query?

How Soon It Starts Working

The time required for Planit Tablet 21's to start to work: Planit Tablet 21's ideally shows its action within 7 days of consistent use. 

The time for which the effects of Planit Tablet 21's last: The effect of Planit Tablet 21's lasts for 7.7 to 15 hours.

What if you forget to take Planit Tablet 21's

If you miss a dose, take it as soon as you remember, even if that means taking two tablets in one day. Continue taking your subsequent tablets at your regular scheduled time. Depending on when and how many tablets you missed, you may need to use a backup barrier method of contraception (such as condoms) for the next 7 days. Please consult the patient leaflet that came with your pack or talk to your doctor or pharmacist for precise guidance based on your specific cycle week.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inspect the medicine before use: Always check the expiration date and ensure the blister pack is intact before taking your tablet.
  • Take your tablet at the same time every day: Consistent daily dosing helps maintain reliable contraceptive protection. Consider using an alarm or reminder app to avoid missed doses.
  • Use backup contraception when needed: If you experience severe vomiting or diarrhea within 3 to 4 hours of taking a tablet, treat it as a missed dose and use a backup contraceptive method, such as condoms, for the next 7 days.
  • Inform healthcare providers before surgery: Tell your surgeon or doctor if you have a planned surgery or expect prolonged immobility. You may need to stop Planit Tablet 21's several weeks before the procedure to help reduce the risk of blood clots.
  • Remember the limitations of protection: Planit Tablet 21's helps prevent pregnancy but does not protect against HIV or other sexually transmitted infections. Use condoms if protection against sexually transmitted infections is needed.
  • Follow the correct starting instructions: Contraceptive protection usually begins immediately if the medicine is started on the first day of your menstrual period. If started on any other day, use a reliable backup contraceptive method for the first 7 days.
  • Seek advice when changing contraceptive methods: Consult your doctor or pharmacist for guidance when switching from another birth control pill, injection, implant, IUD, or patch to help maintain continuous contraceptive protection.
  • Use with special care after childbirth or abortion: The appropriate time to start Planit Tablet 21's after childbirth, abortion, or during breastfeeding depends on your individual situation. Follow your healthcare provider’s instructions carefully.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Anti-seizure medicines (e.g., carbamazepine, phenytoin, phenobarbital): These medicines can reduce the effectiveness of Planit Tablet 21's and increase the risk of unintended pregnancy.
  • Tuberculosis medicines (e.g., rifampin): Taking these alongside Planit Tablet 21's can significantly lower hormone levels in the body, making the contraceptive less reliable.
  • Herbal supplements (e.g., St. John's Wort): These supplements may speed up the breakdown of hormones in Planit Tablet 21's, increasing the risk of breakthrough bleeding and contraceptive failure.

Drug-Food Interactions

  • Grapefruit and grapefruit juice: Consuming grapefruit products while taking Planit Tablet 21's may increase hormone levels in the bloodstream and raise the risk of side effects.

Drug-Disease Interactions

  • Blood clotting disorders: Planit Tablet 21's can significantly increase the risk of dangerous blood clots in people with existing clotting disorders.
  • Severe liver disease: Do not take Planit Tablet 21's if you have active liver disease or liver tumors, as it may worsen liver function.
  • Uncontrolled high blood pressure: Planit Tablet 21's may further increase blood pressure and raise the risk of serious complications such as stroke or heart attack.
  • Migraines with aura: Planit Tablet 21's may increase the risk of stroke in people who experience migraines accompanied by visual disturbances or other neurological symptoms
Ethinylestradiol + LevonorgestrelEtretinate
Critical
Ethinylestradiol + LevonorgestrelAcitretin
Critical

Drug-Drug Interactions

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Ethinylestradiol + LevonorgestrelEtretinate
Critical
How does the drug interact with Planit Tablet:
Using Etretinate with Ethinylestradiol, Levonorgestrel can increase the risk of side effects during pregnancy.

How to manage the interaction:
Taking Etretinate with Ethinylestradiol, Levonorgestrel can cause an interaction, consult a doctor before taking it. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
Ethinylestradiol + LevonorgestrelAcitretin
Critical
How does the drug interact with Planit Tablet:
Co-administration of Acitretin with Ethinylestradiol, Levonorgestrel can increase the risk of side effects during pregnancy.

How to manage the interaction:
Taking Acitretin with Ethinylestradiol, Levonorgestrel together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not stop using any medications without talking to a doctor.
Ethinylestradiol + LevonorgestrelTranexamic acid
Critical
How does the drug interact with Planit Tablet:
Taking Ethinylestradiol, Levonorgestrel with Tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Ethinylestradiol, Levonorgestrel with Tranexamic acid can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you experience any symptoms like chest tightness, shortness of breath, blood in the urine, blood in the cough, disturbances in eye sight or swelling in the arms or legs, consult a doctor. Do not stop using any medications without talking to a doctor.
Ethinylestradiol + LevonorgestrelBoceprevir
Severe
How does the drug interact with Planit Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Boceprevir together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Boceprevir, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ethinylestradiol + LevonorgestrelPhenytoin
Severe
How does the drug interact with Planit Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Phenytoin together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Phenytoin, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ethinylestradiol + LevonorgestrelAnastrozole
Severe
How does the drug interact with Planit Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Anastrozole together may decrease the blood levels of anastrozole.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Anastrozole, they can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ethinylestradiol + LevonorgestrelPrimidone
Severe
How does the drug interact with Planit Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Primidone together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Primidone, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ethinylestradiol + LevonorgestrelRifampicin
Severe
How does the drug interact with Planit Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Rifampicin together may decrease the blood levels of Rifampicin.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Rifampicin, they can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ethinylestradiol + LevonorgestrelBexarotene
Severe
How does the drug interact with Planit Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Bexarotene together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Bexarotene, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ethinylestradiol + LevonorgestrelRifapentine
Severe
How does the drug interact with Planit Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Rifapentine together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Rifapentine, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CONTRACEPTIVES]

FAQs

Planit Tablet 21's is used for contraception and treating dysmenorrhea (irregular and painful periods).
Yes, Planit Tablet 21's can cause spotting in between the regular periods. Usually, it does not persist, but if spotting does not, please inform your doctor, as medical attention may be required.
Yes, Planit Tablet 21's is known to cause weight gain. So, avoid weight gain, exercise regularly, and eat home-cooked food.
No, the Planit Tablet 21's does not protect against sexually transmitted diseases (STDs). It is an oral form of contraception that does not protect against STDs. So, use some other form of contraception, like condoms, to avoid transmission.
You will usually get your period within three days after taking the last pill. If you have not followed the dosing schedule like you have missed one or two pills or started taking them a day after, you should have the probability of pregnancy at the time of the first missed period, and you should contact your doctor.
Do not take Planit Tablet 21's if you have a heart fitted with an artificial valve, heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), confirmed or suspected ectopic pregnancy, have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Planit Tablet 21's in these conditions can cause life-threatening conditions in an individual.
If you forget to take one tablet of Planit Tablet 21's, take it as soon as you remember, even if it means taking two tablets at the same time and then follow the usual dosing schedule. However, if you forget to take two or more doses, you may not be completely protected against pregnancy. In this case, start taking the Planit Tablet 21's as soon as you remember and use a non-hormonal method of contraception such as condoms for at least the next 7 days to prevent pregnancy. Frequent missing doses may cause spotting (bloodstain) or unexpected vaginal bleeding. If this persists, contact your doctor.
Planit Tablet 21's is contraindicated in women with a history of breast and cervical cancer. Women with known or suspected carcinoma of the breast or personal history of breast cancer should not use Planit Tablet 21's because breast cancer is usually a hormonally-sensitive tumor, and Planit Tablet 21's slightly increases your risk of breast cancer.Therefore, inform your doctor if you have had a history of breast cancer before taking Planit Tablet 21's.
Yes, Planit Tablet 21's is a 21-day oral contraceptive pill used for regulating periods and preventing pregnancy.
To take Planit Tablet 21's, swallow the tablet whole with a glass of water. Do not chew, crush, or break it. Your doctor will determine the correct dose based on your medical condition. If you have any concerns, please consult your doctor.
Smokers over 35 should avoid taking Planit Tablet 21's due to increased risks of blood clots, stroke, and heart attack. If you're a smoker, consult your doctor for guidance on safer alternatives or to discuss any concerns.
If you vomit within 3-4 hours of taking Planit Tablet 21's, take another tablet as soon as possible to maintain effectiveness. However, please consult a doctor if vomiting persists or worsens.
The common side effects of Planit Tablet 21's include stomach pain, nausea, headache, breast tenderness, weight gain, and irregular menstrual bleeding. Most of these side effects are temporary and resolve on their own. However, if they persist, consult your doctor for guidance.
The hormones in Planit Tablet 21's can pass into breast milk and may also slightly reduce the quantity and quality of your milk. It is generally recommended to use other forms of contraception while breastfeeding. Talk to your doctor or pharmacist to find a safer alternative
If you start taking Planit Tablet 21's on the first day of your menstrual period, it is usually effective immediately. If you start on any other day of your cycle, it can take up to 7 days of continuous daily use to become fully effective. You should use a backup contraceptive, like condoms, during these first 7 days.
Yes, common pain relievers like ibuprofen or acetaminophen do not typically interact with Planit Tablet 21's or reduce its contraceptive effectiveness. However, always let your pharmacist know all the medications you are taking to prevent any unexpected issues. Talk to your doctor for personalized advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Ethinyl Estradiol And Levonorgestrel Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.9565 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.1127 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. U.S. Food and Drug Administration (FDA). 020683S012Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  5. Ezinelle 1.5 mg tablet - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 27 April 2021] Check here
  6. Ezinelle 1.5 mg tablet - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 27 April 2021]Check here

Country of origin

India

Manufacturer/Marketer address

Block 6, Sharda Puri, Delhi, 110015
Other Info - PLA0489

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