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  3. Plerixa 24 mg Injection 1.2 ml

Plerixa 24 mg Injection 1.2 ml, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Plerixa 24 mg Injection is used in the treatment of Non-Hodgkin’s Disease (a blood cancer that affects your lymph system) and multiple myeloma (a type of cancer that affects the plasma cells of the bone marrow). Plerixa 24 mg Injection contains Plerixafor, which belongs to the hemopoietic stem cell mobilizer class or drugs. It works by releasing stem cells from the bone marrow, making them available to collect from your bloodstream.

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Composition :

PLERIXAFOR-24MG

Manufacturer/Marketer :

Therdose Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Plerixa 24 mg Injection

Plerixa 24 mg Injection belongs to the class of hemopoietic stem cell mobilizer. It is used in the treatment of Non-Hodgkin’s Disease (a blood cancer that affects your lymph system) and multiple myeloma (a type of cancer that affects the plasma cells of the bone marrow) in combination with granulocyte-colony stimulating factor (G-CSF).

Plerixa 24 mg Injection contains Plerixafor, which belongs to the hemopoietic stem cell mobilizer class or drugs. It works by binding to the chemokine receptor CXCR4 and inhibits the binding of its cognate ligand CXCL12.

Plerixa 24 mg Injection may cause certain side effects, such as nausea, vomiting, headache, dizziness, diarrhoea, flatulence, fatigue, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. A trained healthcare professional will administer it. Do not self-administer.

Avoid taking it and inform your doctor if you are allergic to Plerixa 24 mg Injection or its components. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, blood disorders or respiratory conditions. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued during the treatment.

Uses of Plerixa 24 mg Injection

Plerixa 24 mg Injection is used in the treatment of Multiple Myeloma and Non-Hodgkin's Disease. The detailed uses of Plerixa 24 mg Injection are as follows:<br/>• Stem cell mobilization: Plerixa 24 mg Injection is used in combination with granulocyte-colony stimulating factor (G-CSF) to help the bone marrow release hematopoietic stem cells into the bloodstream. These cells are then collected for autologous stem cell transplantation, a procedure often used in cancer treatment.<br/>• Treatment of certain cancers: Plerixa 24 mg Injection is indicated for patients with non-Hodgkin’s lymphoma and multiple myeloma who are undergoing stem cell transplantation. By increasing the number of stem cells in the blood, it improves the success rate of the transplant.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication. Typically, it is injected once a day, 11 hours prior to blood cell removal, for up to 4 days in a row.• Plerixa 24 mg Injection will be administered under the skin by a doctor or nurse in a medical facility.• Do not self-administer.

Medicinal Benefits

Plerixa 24 mg Injection contains Plerixafor, which belongs to the hemopoietic stem cell mobilizer class or drugs. It works by binding to the chemokine receptor CXCR4 and inhibiting its cognate ligand CXCL12 binding. This mobilizes hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in cancer patients.

How Plerixa 24 mg Injection Works

Plerixa 24 mg Injection contains Plerixafor, which belongs to the hemopoietic stem cell mobilizer class or drugs. It works by binding to the chemokine receptor CXCR4 and inhibits the binding of its cognate ligand CXCL12.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Plerixa 24 mg Injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Plerixa 24 mg Injection 1.2 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Plerixa 24 mg Injection

As Plerixa 24 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Plerixa 24 mg Injection may cause nausea, vomiting, stomach pain, diarrhea, gas, dizziness or lightheadedness, and fainting.

Drug Warnings

Plerixa 24 mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, blood disorders, anaemia, or respiratory conditions. Plerixa 24 mg Injection may cause the potential for tumor cell mobilization in leukemia patients, haematological effects, and splenic rupture in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. Plerixa 24 mg Injection should be avoided in children as safety is not established.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Plerixa 24 mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is unknown whether Plerixa 24 mg Injection interacts with alcohol or not. Please consult your doctor.

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Pregnancy

Unsafe

Plerixa 24 mg Injection is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Plerixa 24 mg Injection . Effective birth control is necessary during treatment and for one week after your last dose.

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Breast Feeding

Unsafe

Plerixa 24 mg Injection is not recommended if you are breastfeeding. You should not breastfeed while taking this medication and for one week after your last dose.

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Driving

Caution

Plerixa 24 mg Injection is generally administered to hospitalized patients. Driving is not advised after taking this medicine.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Plerixa 24 mg Injection . A dose adjustment may be made, or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Plerixa 24 mg Injection . A dose adjustment may be made, or a suitable alternative may be advised based on your condition.

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Children

Unsafe

Plerixa 24 mg Injection is not recommended for use in children as the safety and efficacy are not established.

Have a query?

FAQs

Plerixa 24 mg Injection is used to treat Multiple Myeloma, Non-Hodgkin’s Disease.

Plerixa 24 mg Injection contains Plerixafor, which works by binding to the chemokine receptor CXCR4 and inhibits the binding of its cognate ligand CXCL12.

Plerixa 24 mg Injection may cause tumor cell mobilization and haematological effects such as increased lymphocytes, decreased platelet count, and splenic rupture in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Country of origin

India

Manufacturer/Marketer address

Plot No'S : 118 - 120, Road No.6, Aleap Ie, Pragathi Nagar, Gajularamaram Village, Kukatpally, Hyderabad ,Telangana - 500 072, India.
Other Info - PLE0092

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://go.drugbank.com/drugs/DB06809
  2. https://reference.medscape.com/drug/mozobil-plerixafor-342168
  3. https://medlineplus.gov/druginfo/meds/a609018.html
  4. https://www.oncolink.org/cancer-treatment/oncolink-rx/plerixafor-mozobil-r
  5. https://www.mozobil.com/healthcare/about-mozobil

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