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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Polymyx- B Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Polymyx- B Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Whats That

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

AAA Pharma Trade Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Polymyx- B Injection

Polymyx- B Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Polymyx- B Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Polymyx- B Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Polymyx- B Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Polymyx- B Injection

Treatment of Bacterial infections

Directions for Use

Polymyx- B Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Polymyx- B Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Polymyx- B Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Polymyx- B Injection Works

Polymyx- B Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Polymyx- B Injection

As Polymyx- B Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Polymyx- B Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Polymyxin bEverolimus
Severe
Polymyxin bNetilmicin
Severe

Drug-Drug Interactions

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Polymyxin bEverolimus
Severe
How does the drug interact with Polymyx- B Injection:
Taking Everolimus and Polymyx- B Injection together may increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Everolimus and Polymyx- B Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bNetilmicin
Severe
How does the drug interact with Polymyx- B Injection:
Co-administration of Netilmicin with Polymyx- B Injection can increase the risk of side effects.

How to manage the interaction:
Co-administration of Netilmicin with Polymyx- B Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bAtracurium
Severe
How does the drug interact with Polymyx- B Injection:
Co-administration of Polymyx- B Injection with Atracurium may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Polymyx- B Injection and Atracurium, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bBacitracin
Severe
How does the drug interact with Polymyx- B Injection:
Taking Polymyx- B Injection and Bacitracin together can increase the risk of kidney and inner ear damage

How to manage the interaction:
Although taking Polymyx- B Injection and Bacitracin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience ringing in the ears, hearing loss, vertigo, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bTobramycin
Severe
How does the drug interact with Polymyx- B Injection:
Taking Tobramycin with Polymyx- B Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Polymyx- B Injection, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Polymyxin bVecuronium
Severe
How does the drug interact with Polymyx- B Injection:
Co-administration of Polymyx- B Injection and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Polymyx- B Injection with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bAdefovir dipivoxil
Severe
How does the drug interact with Polymyx- B Injection:
Taking Adefovir dipivoxil with Polymyx- B Injection may increase the risk of side effects.

How to manage the interaction:
Although taking Polymyx- B Injection and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bTacrolimus
Severe
How does the drug interact with Polymyx- B Injection:
Taking Tacrolimus with Polymyx- B Injection may increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Polymyx- B Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Polymyxin bCholera, live attenuated
Severe
How does the drug interact with Polymyx- B Injection:
Taking Polymyx- B Injection and Cholera together may lead to a decrease in the effectiveness of the vaccine.

How to manage the interaction:
There may be a possibility of interaction between Polymyx- B Injection and Cholera, live attenuated, but it can be taken if prescribed by a doctor. It is advised not to receive the cholera vaccination until at least 14 days after finishing your Polymyx- B Injection therapy in order to ensure an appropriate immune response. Do not discontinue any medications without a doctor's advice.
Polymyxin bTubocurarine
Severe
How does the drug interact with Polymyx- B Injection:
Co-administration of Polymyx- B Injection and Tubocurarine together may cause serious breathing problems.

How to manage the interaction:
There may be a possibility of interaction between Polymyx- B Injection and Tubocurarine, but it can be taken if prescribed by a doctor. However, if you experience any breathing difficulty, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Polymyx- B Injection Substitute

Substitutes safety advice
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  • Fixmac-B Injection

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    2205.00per tablet
  • Hixpoly 5L Injection

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    1615.95per tablet
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Polymyx- B Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Polymyx- B Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Polymyx- B Injection. Caution is advised while administering Polymyx- B Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Polymyx- B Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Polymyx- B Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Polymyx- B Injection.

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Children

Safe if prescribed

Polymyx- B Injection may be safe for use in children if prescribed by the doctor.

Have a query?

FAQs

Polymyx- B Injection is used to treat Bacterial infections.

Polymyx- B Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Polymyx- B Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Polymyx- B Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Polymyx- B Injection will be administered by a healthcare professional. Do not self-administer.

Yes, Polymyx- B Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Polymyx- B Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

E-11, MOTI NAGAR , NEW DELHI-110015
Other Info - POL0102

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