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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pomyelo-4 Tablet is used to treat a type of blood cancer called multiple myeloma in adults 18 years or older. It contains Pomalidomide. Pomalidomide is both a targeted therapy drug and an immunotherapy drug, which works in several different ways. It can help the immune system attack and destroy cancer cells (immune system modulator); it kills or stops cancer cells' growth (cancer growth inhibitor). On the other side, it can block the development of new blood vessels, which cancer cells need to grow and spread (angiogenesis inhibitor).

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Whats That

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Composition :

POMALIDOMIDE-4MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pomyelo-4 Tablet

Pomyelo-4 Tablet belongs to the group of immunomodulatory drugs used to treat a type of blood cancer called multiple myeloma in adults 18 years or older. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer that affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Pomyelo-4 Tablet contains Pomalidomide. Pomalidomide is both a targeted therapy drug and an immunotherapy drug. It works in several different ways. It can help the immune system attack and destroy cancer cells (immune system modulator); it kills or stops cancer cells' growth (cancer growth inhibitor). On the other side, it can block the development of new blood vessels, which cancer cells need to grow and spread (angiogenesis inhibitor).

Pomyelo-4 Tablet is a prescription-only medicine. Take Pomyelo-4 Tablet as prescribed. Pomyelo-4 Tablet may be taken with or without food. In some cases, Pomyelo-4 Tablet may cause certain common side effects such as nausea, rash or allergic reactions, breathing problems, infection, low blood counts, bruising, chest pain, constipation, confusion, dizziness, diarrhoea, fever, faintness, and headaches. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

Before taking the Pomyelo-4 Tablet , inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Pomyelo-4 Tablet can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months afterwards. Before beginning treatment, discuss effective contraception with your healthcare professional. Inform them immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk.

Uses of Pomyelo-4 Tablet

Treatment of Multiple myeloma

Directions for Use

Take Pomyelo-4 Tablet exactly as directed by the physician. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Pomyelo-4 Tablet contains Pomalidomide. It is both a targeted therapy drug and an immunotherapy drug. It works in several different ways. It can assist the immune system in attacking and destroying cancer cells (immune system modulator) and kill or stop cancer cell growth (cancer growth inhibitor). On the other hand, it can prevent the formation of new blood vessels, which cancer cells require in order to grow and spread (angiogenesis inhibitor).

How Pomyelo-4 Tablet Works

Pomyelo-4 Tablet contains Pomalidomide. Pomalidomide is both a targeted therapy drug and an immunotherapy drug. It works in several different ways. It can help the immune system attack and destroy cancer cells (immune system modulator); it kills or stops cancer cells' growth (cancer growth inhibitor). On the other side, it can block the development of new blood vessels, which cancer cells need to grow and spread (angiogenesis inhibitor).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pomyelo-4 Tablet

  • Anaemia
  • Fatigue (tiredness)
  • Nausea
  • Rash or Allergic Reactions
  • Breathing Problems
  • Infection
  • Low Blood Counts
  • Bruising
  • Chest Pain
  • Constipation
  • Confusion
  • Dizziness
  • Diarrhea
  • Fever
  • Feeling Faint
  • Headache
  • Injury
  • Swelling
  • Itching
  • Numbness
  • Weakness
  • Pain

What if I have taken an overdose of Pomyelo-4 Tablet

As Pomyelo-4 Tablet is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Before taking Pomyelo-4 Tablet , inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Avoid taking Pomyelo-4 Tablet if you are pregnant or breastfeeding or allergic to any component present in Pomyelo-4 Tablet . Both women and men using this Pomyelo-4 Tablet should use birth control to avoid pregnancy. Inform your doctor if you have a history of infections; your doctor will closely monitor and manage it. Pomalidomide can lower the number of red blood cells, white blood cells, and platelets in the blood. Anaemia and weariness can result from a low red blood cell count. A blood transfusion may be required if you are anaemic. A low white blood cell count increases the risk of infection, necessitating additional precautions such as rigorous hand washing and avoiding infected people. A fever or temperature of 37°C or above indicates infection. If a patient's temperature is 380 C or higher, medical attention should be sought right away.

Drug-Drug Interactions

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PomalidomideBCG vaccine
Critical
PomalidomideChlorotrianisene
Severe

Drug-Drug Interactions

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PomalidomideBCG vaccine
Critical
How does the drug interact with Pomyelo-4 Tablet:
Taking the BCG vaccine with Pomyelo-4 Tablet can increase the risk of infection.

How to manage the interaction:
Taking Pomyelo-4 Tablet with BCG vaccine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
PomalidomideChlorotrianisene
Severe
How does the drug interact with Pomyelo-4 Tablet:
Taking Chlorotrianisene with Pomyelo-4 Tablet can cause dangerous blood clots, the risk is increased with age, cigarette smoking, high blood pressure, or high cholesterol.

How to manage the interaction:
Co-administration of Chlorotrianisene with Pomyelo-4 Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, difficulty breathing, blood in the cough, sudden loss of vision, pain, redness, or swelling in an arm or leg, as well as numbness or weakness on one side of the body, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideDurvalumab
Severe
How does the drug interact with Pomyelo-4 Tablet:
Taking Pomyelo-4 Tablet with Durvalumab can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Pomyelo-4 Tablet with Durvalumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideDiethylstilbestrol
Severe
How does the drug interact with Pomyelo-4 Tablet:
Taking Pomyelo-4 Tablet with Diethylstilbestrol together can increase the risk of blood clots.

How to manage the interaction:
There may be a possibility of interaction between Pomyelo-4 Tablet and Diethylstilbestrol, but it can be taken if prescribed by a doctor. However, if you experience chest pain, difficulty breathing, blood in the cough, sudden loss of vision, pain, redness, or swelling in an arm or leg, as well as numbness or weakness on one side of the body, consult a doctor. Do not stop using any medications without talking to a doctor.
PomalidomideFingolimod
Severe
How does the drug interact with Pomyelo-4 Tablet:
Taking Pomyelo-4 Tablet with Fingolimod may increase the risk of serious and potentially life-threatening infections.

How to manage the interaction:
Although taking Pomyelo-4 Tablet and Fingolimod together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideInfliximab
Severe
How does the drug interact with Pomyelo-4 Tablet:
When Pomyelo-4 Tablet is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Pomyelo-4 Tablet and Infliximab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
PomalidomideGolimumab
Severe
How does the drug interact with Pomyelo-4 Tablet:
When Pomyelo-4 Tablet is taken with Golimumab, it can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Pomyelo-4 Tablet and Golimumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideEltrombopag
Severe
How does the drug interact with Pomyelo-4 Tablet:
Co-administration of Eltrombopag with Pomyelo-4 Tablet can increase the risk or severity of developing blood clots.

How to manage the interaction:
Taking Eltrombopag with Pomyelo-4 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of the body, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
PomalidomideClozapine
Severe
How does the drug interact with Pomyelo-4 Tablet:
Taking Pomyelo-4 Tablet with Clozapine can increase the risk of serious infections.

How to manage the interaction:
Although taking Pomyelo-4 Tablet and Clozapine together can cause an interaction, it can be taken if a doctor has suggested it. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor. Do not stop using any medications without a doctor's advice.
PomalidomideLeflunomide
Severe
How does the drug interact with Pomyelo-4 Tablet:
Combining Pomyelo-4 Tablet with Leflunomide can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Pomyelo-4 Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Pomyelo-4 Tablet Substitute

Substitutes safety advice
  • Pomalid 4mg Capsule 21's

    by AYUR

    622.65per tablet
  • Adpomide 4 mg Capsule 21's

    by Others

    869.05per tablet
  • Pomalong 4 mg Capsule 21's

    by Others

    952.38per tablet
  • Pomide 4 mg Capsule 21's

    by Others

    711.45per tablet
  • Pomamac-4 Capsule 21's

    by Others

    728.52per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Pomyelo-4 Tablet .

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Pregnancy

Unsafe

Pomyelo-4 Tablet should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy.

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Breast Feeding

Unsafe

You should not breastfeed when taking Pomyelo-4 Tablet as it is unknown if the Pomalidomide can pass to your baby in the milk.

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Driving

Caution

This treatment will make you feel very tired. If you feel tired or sleepy, do not drive or use machinery.

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Liver

Caution

Treatment with Pomyelo-4 Tablet may affect how your liver works. Please inform your doctor before prescribing Pomyelo-4 Tablet if you have liver impairment. Your doctor will weigh the benefits and potential risks before prescribing Pomyelo-4 Tablet .

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Kidney

Caution

Treatment with Pomyelo-4 Tablet may affect how your kidneys work. Please inform your doctor before prescribing Pomyelo-4 Tablet if you have kidney impairment. Your doctor will weigh the benefits and potential risks before prescribing Pomyelo-4 Tablet .

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Children

Consult your doctor

It is not known if Pomyelo-4 Tablet is safe and effective in children.

FAQs

Pomyelo-4 Tablet is used to treat Multiple myeloma.

Pomyelo-4 Tablet contains Pomalidomide. Pomalidomide is both a targeted therapy drug and an immunotherapy drug. It works in several different ways. It can help the immune system to attack and destroy cancer cells (immune system modulator); it kills or stops the growth of cancer cells (cancer growth inhibitor). On the other side, it can block the development of new blood vessels, which cancer cells need to grow and spread (angiogenesis inhibitor).

No, it is unsafe to father a child while taking Pomyelo-4 Tablet . It is recommended for sexually active men to use condoms while on treatment and for at least six months after their last dose of Pomyelo-4 Tablet .

Pomyelo-4 Tablet can affect the results of this blood test. Tell the person doing the test that you are using Pomyelo-4 Tablet .

Based on the medical condition, Pomyelo-4 Tablet may be given alone or with other medicines used to treat multiple myeloma.

Pomyelo-4 Tablet can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.

It is recommended that you complete the course of Pomyelo-4 Tablet even if you feel better. To treat your condition effectively, continue taking Pomyelo-4 Tablet for as long as your doctor has prescribed it.

If you miss the dose of Pomyelo-4 Tablet , take it as soon as you remember. If it is almost time for the next dose, skip the forgotten dose and go back to your regular schedule. Do not take double the dose to compensate for the forgotten dose.

No, Pomyelo-4 Tablet is not a steroid. It is a third-generation immunomodulatory drug.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - POM0016

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