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Posanat 300 mg Injection 16.7 ml
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Delivery Information
More about the Product
Composition :
POSACONAZOLE-18MG
Manufacturer/Marketer :
Natco Pharma Ltd
Consume Type :
Parenteral
Expires on or after :
Jan-27
Return Policy :
Not Returnable
About Posanat 300 mg Injection 16.7 ml
Posanat 300 mg Injection 16.7 ml is an antifungal medicine given by injection into a vein to prevent and treat serious, invasive fungal infections. It is typically prescribed for people with weakened immune systems, such as those undergoing chemotherapy or receiving an organ transplant. This medicine helps stop the spread of severe fungal overgrowth in the body.
Because this medicine is given directly into a vein by a healthcare provider, it does not rely on food absorption like oral forms do. Your healthcare team will schedule and give these injections consistently to maintain steady medicine levels in your blood. Staying hydrated and eating a balanced diet support your body's immune system during treatment.
While using Posanat 300 mg Injection 16.7 ml, you may experience mild side effects like nausea, diarrhea, or headache. However, you must contact your doctor immediately if you experience signs of liver damage, such as yellowing of your skin or eyes, dark urine, or severe abdominal pain.
Talk to your doctor before starting Posanat 300 mg Injection 16.7 ml if you have a history of irregular heartbeats, kidney disease, or liver problems. Do not take this if you are allergic to similar antifungal medicines or if you have a family history of heart rhythm issues.
Posanat 300 mg Injection 16.7 ml can interact with other drugs, particularly cholesterol-lowering medicines or blood thinners, by changing how your body processes them. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe for your specific situation.
Uses of Posanat 300 mg Injection 16.7 ml
This medicine is used to treat and prevent serious fungal infections, particularly in people with weakened immune systems. The detailed uses of this medicine are as follows:
- Prevention of serious fungal infections: Helps protect people with severely weakened immune systems, such as those with leukemia or those who have undergone a stem cell transplant, from developing life-threatening fungal infections.
- Treatment of invasive aspergillosis: Helps treat severe infections caused by Aspergillus species, particularly in patients who cannot tolerate or have not responded adequately to other antifungal treatments.
- Treatment of oropharyngeal candidiasis: Oral forms of Posanat 300 mg Injection 16.7 ml may also be used to treat fungal infections of the mouth and throat (oropharyngeal candidiasis). However, the intravenous formulation is primarily used for serious invasive fungal infections or when oral treatment is not suitable.
Key Benefits
This medicine helps treat or prevent serious fungal infections and supports recovery in people at high risk of invasive fungal disease. Its benefits include:
- Helps prevent life-threatening fungal infections in people with severely weakened immune systems.
Helps treat serious mold and yeast infections by reaching infected tissues throughout the body. - Provides rapid treatment when given by injection, allowing the medicine to enter the bloodstream directly without relying on absorption through the digestive system.
- Supports faster recovery by controlling fungal infections before they can cause severe complications.
Side effects of Posanat 300 mg Injection 16.7 ml
- Avoid alcohol as it may be harmful and worsen certain condition.
- Take nutritional supplements only as advised by your doctor.
- Limit sodium intake.
- Consult your doctor for medications to treat your condition effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here's a comprehensive approach to managing medication-triggered fever:
- Inform your doctor immediately if you experience a fever after starting a new medication.
- Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
- Monitor your body temperature to monitor fever progression.
- Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
- Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
- Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
- If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
- Tell your doctor immediately if you experience shortness of breath after taking medication.
- Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
- Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
- For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
- Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
- Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
- Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the steps to cope with constipation as a side effect of medication:
- Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
- Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
- Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
- Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
- Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
- Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Directions for Use
- Your doctor will determine the dosage and frequency depending on your condition.
- Posanat 300 mg Injection 16.7 ml will be administered by a healthcare professional.
- Do not self-administer.
How Posanat 300 mg Injection 16.7 ml Works
Posanat 300 mg Injection 16.7 ml belongs to a class of medicines called azole antifungals. It works by blocking the fungus's ability to produce ergosterol, which is an essential building block of the fungal cell membrane. Without a stable cell membrane, the fungal cells become weak, leak their contents, and eventually die. This stops the spread of the infection and allows your body's immune system to clear the remaining fungi.
Alcohol
Caution
Limit or avoid consumption of alcohol while on treatment with Posanat 300 mg Injection 16.7 ml as it may increase the risk of serious side effects.
Pregnancy
Caution
Posanat 300 mg Injection 16.7 ml is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posanat 300 mg Injection 16.7 ml.
Breast Feeding
Caution
There is no substantial research yet on using Posanat 300 mg Injection 16.7 ml in breastfeeding women. Inform your doctor if you are a nursing mother before taking Posanat 300 mg Injection 16.7 ml; your doctor will decide whether Posanat 300 mg Injection 16.7 ml can be taken by breastfeeding mothers.
Driving
Caution
It is unknown whether Posanat 300 mg Injection 16.7 ml alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.
Liver
Caution
Inform your doctor before receiving the Posanat 300 mg Injection 16.7 ml if you have a liver impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
Kidney
Caution
Inform your doctor before receiving the Posanat 300 mg Injection 16.7 ml if you have a kidney impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
Children
Consult your doctor
Please consult your doctor. Your doctor will prescribe a suitable dose based on your child's age and condition.
Heart
Caution
Posanat 300 mg Injection 16.7 ml should be used cautiously in heart patients due to its potential to cause arrhythmias, especially when combined with certain medications. Always consult your cardiologist and monitor ECG and electrolytes during treatment.
Geriatrics
Caution
Geriatric patients can receive Posanat 300 mg Injection 16.7 ml, as studies show no significant safety differences compared to younger adults. However, kidney function should be monitored closely, and oral therapy may be preferred if renal impairment is present.
What if I have taken an overdose of Posanat 300 mg Injection 16.7 ml
Because this medication is prepared and administered by trained medical staff, an overdose is rare. If you suspect you have received too much, inform your medical team immediately, as they will monitor your symptoms and provide supportive care.
Diet & Lifestyle Advise
- Eat fully cooked foods: Since your immune system may be weak, avoid raw or undercooked meats, seafood, and unpasteurized dairy products to minimize the risk of other infections.
- Stay well-hydrated: Drink plenty of water (unless your doctor tells you otherwise) to help your kidneys process and flush out the medicine efficiently.
- Avoid grapefruit juice: Grapefruit can alter how your body processes this medicine, potentially raising drug levels in your blood and increasing the risk of side effects.
- Maintain good hygiene and avoid infections: Wash your hands regularly, avoid close contact with people who are sick, and follow your healthcare team's infection-prevention advice, especially if your immune system is weakened.
Have a query?
How Soon It Starts Working
The time required for Posanat 300 mg Injection 16.7 ml to start to work: The exact onset time of Posanat 300 mg Injection 16.7 ml has not been clinically established. The time for which the effects of Posanat 300 mg Injection 16.7 ml last: The duration of Posanat 300 mg Injection 16.7 ml’s effect is clinically not established.
What if you forget to take Posanat 300 mg Injection 16.7 ml
Since this medicine is given by a healthcare professional in a clinical setting, missing a dose is unlikely. However, if you miss an appointment or suspect a dose was missed, contact your healthcare provider right away to reschedule your infusion.
Storage
• Unused vials of Posanat 300 mg Injection 16.7 ml must be stored in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze the vials.
Drug Warnings
- Inspect the infusion solution: Before administration, ensure the infusion solution is clear and colorless to pale yellow. Do not use it if you notice cloudiness, discoloration, or visible particles.
- Report injection site reactions: Tell your nurse or healthcare provider immediately if you experience pain, burning, swelling, redness, or coldness at the infusion site.
- Inform your doctor about all medicines: Provide your healthcare provider with a complete list of all prescription medicines, over-the-counter products, and supplements you are taking, as Posanat 300 mg Injection 16.7 ml has the potential for significant drug interactions.
- Attend regular blood tests: Have your liver function and blood electrolyte levels, including potassium and magnesium, monitored as recommended by your doctor during treatment.
- Watch for heart-related symptoms: Contact your healthcare provider immediately if you develop an irregular heartbeat, severe dizziness, or fainting while receiving Posanat 300 mg Injection 16.7 ml.
Drug-Drug Interactions
Drug-Drug Interaction Summary:
- Statins: Posanat 300 mg Injection 16.7 ml may increase the levels of certain cholesterol-lowering medicines (statins), increasing the risk of muscle damage.
- Heart rhythm medicines: Combining with medicines that affect heart rhythm may increase the risk of QT prolongation and serious abnormal heart rhythms.
- Blood thinners: Posanat 300 mg Injection 16.7 ml may increase the effects of some blood thinners, increasing the risk of bleeding. Your doctor may monitor your treatment more closely.
- Calcineurin inhibitors (such as tacrolimus and cyclosporine): Posanat 300 mg Injection 16.7 ml can significantly increase the levels of these medicines, which are commonly used after organ transplantation. Your doctor may need to adjust the dose and monitor blood levels regularly.
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Co-administration of Posanat 300 mg Injection 16.7 ml with Ticagrelor can increase the risk of bleeding.
How to manage the interaction:
Taking Ticagrelor with Posanat 300 mg Injection 16.7 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Co-administration of Posanat 300 mg Injection 16.7 ml with Ticagrelor can increase the risk of bleeding.
How to manage the interaction:
Taking Ticagrelor with Posanat 300 mg Injection 16.7 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
When Dronedarone is taken with Posanat 300 mg Injection 16.7 ml, can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml with Dronedarone is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.
When Dronedarone is taken with Posanat 300 mg Injection 16.7 ml, can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml with Dronedarone is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Taking Posanat 300 mg Injection 16.7 ml with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Posanat 300 mg Injection 16.7 ml with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Coadministration of sirolimus with Posanat 300 mg Injection 16.7 ml can lower the levels of sirolimus in the blood.
How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml with sirolimus, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of sirolimus with Posanat 300 mg Injection 16.7 ml can lower the levels of sirolimus in the blood.
How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml with sirolimus, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleConivaptan
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
When Posanat 300 mg Injection 16.7 ml is taken with Conivaptan, it can increase the blood levels and effects of conivaptan.
How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and conivaptan, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, or mood changes. Do not discontinue any medications without consulting a doctor.
When Posanat 300 mg Injection 16.7 ml is taken with Conivaptan, it can increase the blood levels and effects of conivaptan.
How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and conivaptan, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, or mood changes. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Taking lovastatin with Posanat 300 mg Injection 16.7 ml can increase the levels of lovastatin in the blood which can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between Lovastatin and Posanat 300 mg Injection 16.7 ml, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
Taking lovastatin with Posanat 300 mg Injection 16.7 ml can increase the levels of lovastatin in the blood which can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between Lovastatin and Posanat 300 mg Injection 16.7 ml, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Using ivabradine together with Posanat 300 mg Injection 16.7 ml may significantly increase the blood levels and effects of ivabradine.
How to manage the interaction:
Taking Ivabradine with Posanat 300 mg Injection 16.7 ml together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Using ivabradine together with Posanat 300 mg Injection 16.7 ml may significantly increase the blood levels and effects of ivabradine.
How to manage the interaction:
Taking Ivabradine with Posanat 300 mg Injection 16.7 ml together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Coadministration of Posanat 300 mg Injection 16.7 ml with Ziprasidone can increase the risk of abnormal heart rhythm.
How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Coadministration of Posanat 300 mg Injection 16.7 ml with Ziprasidone can increase the risk of abnormal heart rhythm.
How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Taking Tolvaptan and Posanat 300 mg Injection 16.7 ml together results in an increase in the levels and effects of Tolvaptan.
How to manage the interaction:
Although there is an interaction between Tolvaptan and Posanat 300 mg Injection 16.7 ml, it can be taken if prescribed by a doctor. However, consult a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures (fits). Do not stop using any medications without a doctor's advice.
Taking Tolvaptan and Posanat 300 mg Injection 16.7 ml together results in an increase in the levels and effects of Tolvaptan.
How to manage the interaction:
Although there is an interaction between Tolvaptan and Posanat 300 mg Injection 16.7 ml, it can be taken if prescribed by a doctor. However, consult a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures (fits). Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Coadministration of Posanat 300 mg Injection 16.7 ml with eplerenone can increase the blood levels of eplerenone. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).
How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and eplerenone, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Posanat 300 mg Injection 16.7 ml with eplerenone can increase the blood levels of eplerenone. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).
How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and eplerenone, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interaction Summary:
- Grapefruit and grapefruit juice: Although food does not affect the absorption of the injectable form, avoid grapefruit and grapefruit juice because they can increase Posanat 300 mg Injection 16.7 ml levels in the blood and raise the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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FAQs
Posanat 300 mg Injection 16.7 ml is used to treat Fungal infections.
Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.
Posanat 300 mg Injection 16.7 ml is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posanat 300 mg Injection 16.7 ml.
If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.
Posanat 300 mg Injection 16.7 ml may cause side effects like injection site reactions, diarrhoea, nausea, fever, vomiting, headache and coughing, although not everybody gets them. Most of these side effects of Posanat 300 mg Injection 16.7 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
In some cases, using Posanat 300 mg Injection 16.7 ml may lead to nosebleeds as a side effect. It does not require medical attention and gradually resolves over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, Posanat 300 mg Injection 16.7 ml is effective in the treatment of fungal infections and prevention of invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs).
Posanat 300 mg Injection 16.7 ml is given as a slow intravenous (IV) infusion directly into a vein by a healthcare provider. Talk to your doctor if you have questions about the infusion process.
While it is usually given in a hospital or clinic, some patients may receive it at home under the supervision of a home health nurse. Talk to your doctor to see if this is an option for you.
In some cases, Posanat 300 mg Injection 16.7 ml can cause liver problems. Your doctor will perform regular blood tests to monitor your liver health during treatment. Talk to your doctor if you notice yellowing of your skin or eyes.
It is best to avoid alcohol during treatment, as both alcohol and Posanat 300 mg Injection 16.7 ml can place stress on your liver. Talk to your doctor for personalized advice.
The duration of treatment depends on your infection type and immune system status. Your doctor will decide how long you need the medication. Talk to your doctor about your treatment timeline.
Tell your nurse or doctor immediately if you feel pain, burning, redness, or swelling where the needle is inserted. Talk to your doctor or healthcare team about managing local injection site reactions.
Posanat 300 mg Injection 16.7 ml is generally not recommended during pregnancy unless the benefits outweigh the risks to the unborn baby. Talk to your doctor if you are pregnant or planning to become pregnant.
Depending on your recovery progress, your doctor may transition you from the intravenous infusion to oral tablets or liquid forms of the medicine. Talk to your doctor about whether an oral switch is right for you.
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Reference
- MedlinePlus. A616017 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
- Drugs.com Clinical Review Team. Posaconazole Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
- DrugBank Online. Db01263 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026]Check here
- National Health Service (NHS). Posaconazole Nac Pil - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
- Posaconazole Posaconazole. 2006. [Accessed on 29 Mar. 2019]Check here
- Noxafil [Prescribing Information]. 2015. [Accessed on 25 Jul. 2024]Check here
Country of origin
INDIA
Manufacturer/Marketer address
Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Therapeutic Class
[ANTIFUNGALS]
Habit Forming
No
Other Info - POS0079
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