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compositionComposition:SEMAGLUTIDE-1MG
prescriptionPrescription Medicine
Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's
Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's
Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's
Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is used for weight management in people with obesity or overweight when combined with a reduced-calorie diet and increased physical activity. By supporting weight loss and improving metabolic health, Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in certain individuals with heart disease. Common side effects may include nausea, diarrhoea, vomiting, constipation, abdominal pain, headache, fatigue, dizziness, bloating, and heartburn. 

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SEMAGLUTIDE-1MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is indicated for weight management when used together with a reduced-calorie diet and increased physical activity in individuals with obesity. It also helps to lower the risk of serious heart-related problems, such as heart attack and stroke, in people with obesity or overweight and established heart disease.

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's contains semaglutide, a GLP-1 receptor agonist that mimics a natural hormone involved in appetite regulation. It works by slowing the emptying of food from the stomach, increasing feelings of fullness, and reducing hunger, which helps lower calorie intake and support weight management. It also helps the body regulate blood sugar levels and supports overall metabolic health.

Additionally, by supporting weight loss and improving metabolic health, Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in people who are overweight or obese and have heart disease.

In some cases, Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may cause side effects such as nausea, vomiting, diarrhoea, constipation, abdominal discomfort, dizziness, or altered taste. Talk to your doctor if the side effects persist or worsen.

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is available in a pre-filled multi-dose pen that allows flexible dosing. It features an easy-to-use dialer for accurate dose delivery and is designed for convenient self-administration. Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is not recommended for use in children, during pregnancy, or while breastfeeding.

Uses of Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is used to treat various medical conditions. The detailed uses are as follows:

  • Chronic weight management: Used in individuals with obesity or overweight to help achieve and maintain weight loss when combined with a reduced-calorie diet and increased physical activity.
  • Cardiovascular risk reduction: Helps to lower the risk of serious heart-related problems, such as heart attack and stroke, in people with obesity or overweight and heart disease.

Key Benefits

  • Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's contains semaglutide, a GLP-1 receptor agonist that mimics a naturally occurring hormone that regulates appetite and digestion.
  • It helps reduce calorie intake by slowing gastric emptying, increasing feelings of fullness, and decreasing hunger and food cravings, thereby supporting weight loss.
  • Promotes long-term weight management when combined with a reduced-calorie diet and physical activity, helping patients achieve and maintain a healthy body weight.
  • Improves metabolic health by aiding in better blood sugar control, lowering cholesterol levels, and reducing blood pressure in patients with obesity or overweight.
  • Reduces cardiovascular risk by lowering the chance of major heart-related events (such as heart attack or stroke) in adults with established heart disease who are overweight or obese.
Side effects of Poviztra 0.25 mg Flextouch Prefilled Pen Injection Combipack 1.5 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • A qualified healthcare professional will instruct you on how to administer Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's.
  • It is a once-weekly subcutaneous injection in the abdomen, thigh, or upper arm. It should not be injected intravenously or intramuscularly.
  • Kindly do not self-administer without proper training and medical guidance.

How Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's Works

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's contains semaglutide, which acts like a natural hormone in the body that helps control appetite. It works by slowing the movement of food from the stomach, helping you feel full for longer and reducing hunger. This can help you eat less and support weight loss. It also helps the body control blood sugar levels. By supporting weight loss and improving overall health, Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in certain individuals.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's. It could lead to increased adverse events.

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Pregnancy

Unsafe

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's should not be used during pregnancy as there is a potential risk of harm to the unborn baby. Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is not recommended for women who are pregnant, planning to conceive soon, or not using reliable contraception during therapy.

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Breast Feeding

Unsafe

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is not recommended during breastfeeding as its safety is not established.

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Driving

Caution

Generally does not impair ability to drive; however, dizziness or low blood sugar (if combined with other drugs) may affect alertness.

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Liver

Caution

Inform your doctor before receiving Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's if you have a pre-existing or a history of liver disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's if you have a pre-existing or a history of kidney disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Consult your doctor

It is not recommended for use in children under 18 years of age, as the safety and efficacy have not been established.

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Heart

Safe if prescribed

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is used in patients with heart disease to help reduce the risk of major adverse events such as heart attack and stroke. However, people who have an irregular heartbeat or a very fast heart rate may need closer monitoring during treatment to make sure the medicine is safe and working properly.

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Geriatrics

Caution

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's should be used with caution in elderly patients, as it may be associated with a higher risk of fractures.

What if I have taken an overdose of Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's

As Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is supplied in a pre-filled injection pen, the risk of accidental overdose is low when used as directed. However, an overdose may occur if more than the prescribed dose is taken, such as accidentally administering an extra dose. Symptoms of overdose may include severe nausea, vomiting, and other gastrointestinal symptoms. If an overdose is suspected, seek medical attention immediately. Patients should be monitored for symptoms, and appropriate supportive treatment should be provided.

Diet & Lifestyle Advise

  • Follow a calorie-controlled, balanced diet as advised by your doctor or dietitian. This is essential for weight loss and to maximise the effect of Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's.
  • Choose high-fibre, nutrient-dense foods like vegetables, fruits, whole grains, and lean proteins. These help you feel full longer and support blood sugar control.
  • Avoid high-sugar and high-fat foods, which can slow weight loss and affect blood sugar levels. Limit processed snacks, fried foods, and sugary drinks.
  • Eat smaller, frequent meals and chew slowly to reduce nausea and discomfort, as Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's slows stomach emptying.
  • Stay hydrated by drinking plenty of water throughout the day. This helps prevent dehydration, especially if you experience vomiting or diarrhoea, which are possible side effects.
  • Limit or avoid alcohol, as it can increase the risk of low blood sugar (if you have diabetes or take insulin/sulfonylureas) and may worsen gastrointestinal side effects.
  • Be physically active for at least 150 minutes a week (e.g., brisk walking, cycling, swimming), as regular exercise enhances weight loss and improves blood pressure, cholesterol, and blood sugar.
  • Monitor your blood sugar regularly if you have type 2 diabetes or are taking other diabetes medications, as weight loss and Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may change your medication needs.
  • Keep regular follow-up appointments so your doctor can track your progress, adjust your dose if necessary, and check for side effects or complications.
  • Adopt long-term healthy habits, to help keep the weight off after stopping Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's, continue following a healthy diet and regular physical activity.

Have a query?

How Soon It Starts Working

  • The time required for Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's to start to work: Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's ideally shows its action within 1 hour after administration.
  • The time for which the effects of Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's last: The duration of action for Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is about 24-48 hours.

What if you forget to take Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's

If you miss a dose of Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's, consult your doctor or healthcare professional. They will reschedule the missed dose and may adjust the timing of your next doses if necessary.

Storage

• Store in a refrigerator (2°C to 8°C).
• Do not freeze or use if previously frozen.
• Keep this medicine out of the sight and reach of children.
icon image

Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Do not use Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's if you or a close family member has ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you have ever experienced a severe allergic reaction to semaglutide or any of its ingredients.
  • Let your doctor know about all your medical conditions before using Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's, including if you have or have ever had pancreatitis (inflamed pancreas), gallbladder problems or gallstones, kidney disease, severe digestive issues like gastroparesis (slow stomach emptying), diabetic eye disease (retinopathy), or any mental health concerns such as depression or suicidal thoughts.
  • Inform your doctor about every medicine, vitamin, or herbal supplement you are taking, as Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may change how other medicines are absorbed. For instance, using Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's with insulin or sulfonylureas can increase the risk of low blood sugar, so your doctor may need to adjust other treatments.
  • Do not use Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's if you are pregnant, planning pregnancy, or breastfeeding. Stop the medicine at least 2 months before trying to conceive due to its long-lasting effect in the body. If you find out you are pregnant while using Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's, stop it immediately and call your doctor.
  • It is not recommended for use in children under 18 years of age.
  • Contact your doctor immediately if you experience any severe or persistent side effects, such as ongoing stomach pain (which may signal pancreatitis), signs of an allergic reaction (swelling, rash, difficulty breathing), severe vomiting or diarrhoea leading to dehydration, or mood changes such as depression or suicidal thoughts.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's potentially interacts with certain medications used to treat certain cancers (e.g., bexarotene, capivasertib), certain general anaesthetics (e.g., desflurane, enflurane, etomidate, fospropofol, halothane, isoflurane, ketamine), antibiotics (e.g., gatifloxacin), certain insulin or sulfonylureas (e.g., glimepiride, glyburide) and certain GLP‑1 receptor agonists or similar weight-loss medications (e.g., liraglutide, tirzepatide).

Drug-Food Interactions: There are no significant food restrictions with Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's. However, limit alcohol intake as it can worsen nausea and vomiting and may increase the risk of low blood sugar, particularly if you are using other diabetes medicines.

Drug-Disease Interactions: If you have a history of suicidal behaviour and ideation, thyroid cancer, hypoglycemia, pancreatitis, retinopathy and GI adverse reactions. Inform your doctor before starting treatment with Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's. These conditions may require close monitoring or adjustments to your therapy.

SemaglutideGatifloxacin
Critical
SemaglutideBexarotene
Severe

Drug-Drug Interactions

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SemaglutideGatifloxacin
Critical
How does the drug interact with Poviztra 0.25 mg Flextouch Prefilled Pen Injection Combipack 1.5 ml:
Coadministration of Poviztra 0.25 mg Flextouch Prefilled Pen Injection Combipack 1.5 ml with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Poviztra 0.25 mg Flextouch Prefilled Pen Injection Combipack 1.5 ml can be taken with Gatifloxacin if prescribed by the doctor. Consult the doctor if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without first consulting your doctor.
SemaglutideBexarotene
Severe
How does the drug interact with Poviztra 0.25 mg Flextouch Prefilled Pen Injection Combipack 1.5 ml:
Co-administration of Bexarotene and Poviztra 0.25 mg Flextouch Prefilled Pen Injection Combipack 1.5 ml can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Bexarotene and Poviztra 0.25 mg Flextouch Prefilled Pen Injection Combipack 1.5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's is used for weight management in people with obesity when combined with a reduced-calorie diet and increased physical activity. It may also help lower the risk of serious heart-related problems, such as heart attack and stroke, in people who are overweight or obese and have heart disease.

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's works by acting like a natural hormone in the body that helps control appetite. It helps you feel full for longer, reduces hunger, and slows down the movement of food from the stomach. This can help you eat less and manage your weight more effectively. It also helps the body regulate blood sugar levels. By supporting weight loss and improving metabolic health, Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may help lower the risk of serious heart-related problems, such as heart attack and stroke, in certain individuals with heart disease.

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may cause side effects such as nausea, diarrhoea, vomiting, constipation, abdominal pain, headache, fatigue, upset stomach, dizziness, bloating, belching, low blood sugar (in people with type 2 diabetes), gas, gastroenteritis (stomach flu), heartburn, runny nose, and sore throat. Side effects may vary from person to person depending on individual factors. Consult your doctor if any side effects persist, worsen, or become bothersome.

Pancreatitis (inflammation of the pancreas) is a possible side effect of Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's. Stop using Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's and contact your healthcare provider immediately if you develop severe, persistent stomach pain, with or without nausea or vomiting. The pain may also spread from your abdomen to your back.

Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's may increase the risk of low blood sugar, especially in people with type 2 diabetes who also take insulin or certain diabetes medicines such as sulfonylureas. Checking your blood sugar levels before starting Poviztra 0.25mg/1.5ml Flextouch Prefilled Pen Injection Combipack 1's and during treatment is recommended. Symptoms of low blood sugar may include dizziness, sweating, shakiness, blurred vision, weakness, hunger, headache, anxiety, irritability, confusion, drowsiness, a fast heartbeat, slurred speech, or feeling jittery. If you experience these symptoms, contact your healthcare provider for advice on managing low blood sugar.

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Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - POV0178

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