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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Pradaxa 75 Capsule is used to prevent the formation of blood clots. It contains Dabigatran etexilate mesylate which works by blocking coagulation factor (thrombin) in the blood and prevents blood clot formation. In some cases, this medicine may cause side effects such as bleeding, stomach pain, nausea, and indigestion. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pradaxa 75 Capsule

Pradaxa 75 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Pradaxa 75 Capsule is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Pradaxa 75 Capsule contains Dabigatran etexilate mesylate, which is a new oral blood thinner. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Pradaxa 75 Capsule preventing blood clot formation in the body.

Take Pradaxa 75 Capsule as prescribed by your doctor. You are advised to take Pradaxa 75 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, stomach pain, nausea, and indigestion. Most of these side effects of Pradaxa 75 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Pradaxa 75 Capsule or any other medicines, please tell your doctor. Pradaxa 75 Capsule should not be taken in the conditions like bleeding disorder, or kidney disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Pradaxa 75 Capsule . Pradaxa 75 Capsule should not be used for children below 18 years of age. Pradaxa 75 Capsule has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Pradaxa 75 Capsule as it may increase the risk of bleeding.

Uses of Pradaxa 75 Capsule

Prevention of blood clot

Directions for Use

Take Pradaxa 75 Capsule with or without food as prescribed by the doctor. Swallow it as a whole with a full glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Pradaxa 75 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Pradaxa 75 Capsule is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent blood clots in the heart and prevent heart attacks. Besides this Pradaxa 75 Capsule is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. This Pradaxa 75 Capsule may also be used to prevent the formation of blood clots after hip replacement surgery. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Pradaxa 75 Capsule prevents blood clot formation in the body.

How Pradaxa 75 Capsule Works

Pradaxa 75 Capsule contains Dabigatran etexilate mesylate, which is a new oral blood thinner. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Pradaxa 75 Capsule preventing blood clot formation in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pradaxa 75 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

What if I have taken an overdose of Pradaxa 75 Capsule

Take Pradaxa 75 Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include unusual/prolonged bleeding, bloody/tarry/black stools, and pink/dark urine. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Pradaxa 75 Capsule or any other medicines, please tell your doctor. Pradaxa 75 Capsule should not be taken in the conditions like heart disease, bleeding problems, and kidney disease. Do not take Pradaxa 75 Capsule if you have reduced function of the liver, which might cause death. Inform your doctor if you have a serious injury (bone fracture, head injury). People who have any spinal surgery are more likely to have bleeding problems around the spine when already on this Pradaxa 75 Capsule . This bleeding infrequently occurs but can lead to not moving the body (paralysis) prolonged-term or paralysis that will not go away. Pradaxa 75 Capsule should not be taken if you are older than 75 years. Before taking Pradaxa 75 Capsule inform your doctor if you have a surgery in the past month. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Pradaxa 75 Capsule .  Pradaxa 75 Capsule should not be used for children below 18 years of age. Pradaxa 75 Capsule has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Pradaxa 75 Capsule as it may increase the risk of bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateClopidogrel
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Pradaxa 75 Capsule:
When Mifepristone is taken with Pradaxa 75 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Pradaxa 75 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateClopidogrel
Severe
How does the drug interact with Pradaxa 75 Capsule:
Taking Clopidogrel with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between clopidogrel and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
Dabigatran etexilateDanaparoid
Severe
How does the drug interact with Pradaxa 75 Capsule:
Taking Pradaxa 75 Capsule with Danaparoid can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 75 Capsule with Danaparoid together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDefibrotide
Severe
How does the drug interact with Pradaxa 75 Capsule:
Taking Pradaxa 75 Capsule with Defibrotide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 75 Capsule with Defibrotide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateFlurbiprofen
Severe
How does the drug interact with Pradaxa 75 Capsule:
Taking Flurbiprofen with Pradaxa 75 Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Flurbiprofen and Pradaxa 75 Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience bleeding, feeling dizzy or lightheaded, dark or sticky stools, throwing up blood, severe headache, or feeling weak contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Dabigatran etexilateFenoprofen
Severe
How does the drug interact with Pradaxa 75 Capsule:
Taking Pradaxa 75 Capsule with Fenoprofen can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 75 Capsule with Fenoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateReteplase
Severe
How does the drug interact with Pradaxa 75 Capsule:
Taking Pradaxa 75 Capsule with Reteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 75 Capsule with Reteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateCilostazol
Severe
How does the drug interact with Pradaxa 75 Capsule:
Co-administration of dabigatron etexilate with cilostazol can increase the risk or severity of bleeding.

How to manage the interaction:
Taking dabigatron etexilate with cilostazol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as unusual bleeding or bruising, dizziness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilateDiclofenac
Severe
How does the drug interact with Pradaxa 75 Capsule:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
Dabigatran etexilatePiroxicam
Severe
How does the drug interact with Pradaxa 75 Capsule:
Coadministration of Piroxicam with Pradaxa 75 Capsule can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Piroxicam and Pradaxa 75 Capsule, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DABIGATRAN ETEXILATE MESILATE-75MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE MESILATE-75MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Pradaxa 75 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Pradaxa 75 Capsule treatment.

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  •  Opt for high vitamin K foods (liver, leafy green vegetables, or vegetable oils) as Pradaxa 75 Capsule may lower Vitamin K in your body.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Pradaxa 75 Capsule and lead to unwanted side effects. Hence try to avoid these juices while taking Pradaxa 75 Capsule .
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Pradaxa 75 Capsule Substitute

Substitutes safety advice
  • Dabiclot 75 Capsule 10's

    by AYUR

    23.94per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Pradaxa 75 Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Pradaxa 75 Capsule is a Category C pregnancy drug as the effect of Pradaxa 75 Capsule is unknown on the mother and the unborn baby. Avoid the use of Pradaxa 75 Capsule if you are pregnant and inform your doctor.

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Breast Feeding

Unsafe

Pradaxa 75 Capsule should not be used while taking Pradaxa 75 Capsule . Inform your doctor if you are a breastfeeding mother.

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Driving

Safe if prescribed

Pradaxa 75 Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Pradaxa 75 Capsule with caution, especially if you have a history of Liver diseases/conditions. Pradaxa 75 Capsule may increase the chances of mild liver injury. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pradaxa 75 Capsule with caution, especially if you have a history of Kidney diseases/conditions, as this Pradaxa 75 Capsule may cause side effects. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Pradaxa 75 Capsule should not be used for children below 18 years as it is not approved for children.

Have a query?

FAQs

Pradaxa 75 Capsule is used to prevent blood clots. It is used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung).

People experiencing any uncommon bleeding or people allergic to Pradaxa 75 Capsule should not take Pradaxa 75 Capsule . People with artificial heart valves should also prevent Pradaxa 75 Capsule . Pradaxa 75 Capsule should not take those patients who have bleeding problems and heart disease. The use of this Pradaxa 75 Capsule is not suggested in patients with serious kidney disease.

As compared to other blood thinner medicines, Pradaxa 75 Capsule does not normally cause hair loss. Though, there do exist some unusual reports of hair loss related to Pradaxa 75 Capsule . Inform your doctor if you observe hair loss while taking Pradaxa 75 Capsule .

Yes, Pradaxa 75 Capsule increases the risk of bleeding. Always be cautious while doing activities that may lead to an injury or bleeding. Inform your doctor immediately if you notice any abnormal staining or bleeding.

Pradaxa 75 Capsule works by blocking a substance (a protein known as thrombin) in the blood and preventing blood clot formation. Therefore, Pradaxa 75 Capsule preventing blood clot formation in the body.

Unlike other blood thinners, Pradaxa 75 Capsule generally does not affect the functioning of the liver. But long-term use of Pradaxa 75 Capsule may raise the chances of mild liver injury in patients with a high level of liver enzymes. However, the complete chances of developing any such problem are lesser than other blood thinners. It is advisable to you that before starting this Pradaxa 75 Capsule inform your doctor if you have a history of liver disease.

Pradaxa 75 Capsule may increase the risk of bleeding during surgery. Therefore, the doctor might ask you to stop taking Pradaxa 75 Capsule a few days before surgery.

You can take Pradaxa 75 Capsule with or without food but try to take it at the same time every day. Pradaxa 75 Capsule should be swallowed as a whole with water; do not crush or chew it.

Pradaxa 75 Capsule should be taken as advised by the doctor. To help you remember to take Pradaxa 75 Capsule , take it at around the same time daily.

You are recommended to avoid alcohol consumption with Pradaxa 75 Capsule as it may increase the risk of bleeding.

Though Pradaxa 75 Capsule starts working within a few hours of taking the medicine, you may not feel any better. Keep taking Pradaxa 75 Capsule for the prescribed duration to treat your condition effectively.

Store Pradaxa 75 Capsule at room temperature, in a dry place. Keep out of sight and reach of children.

Pradaxa 75 Capsule may cause side effects like bleeding, stomach pain, nausea, and indigestion. Most of these side effects of Pradaxa 75 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - PRA0214

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