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  3. Predoss 1000mg Injection

Predoss 1000mg Injection, Pack of 1 Injection
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Synonym :

METHYLPREDNISOLONE SODIUM SUCCINATE

Composition :

METHYLPREDNISOLONE-1000MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Predoss 1000mg Injection

Predoss 1000mg Injection belongs to the corticosteroid drug class. It is used to treat symptoms associated with allergic reactions or inflammatory conditions. Predoss 1000mg Injection is primarily used to treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons. It is also useful in treating severe allergic reactions, asthma, ulcerative colitis, and Crohn's disease (inflammatory bowel disease).

Predoss 1000mg Injection contains methylprednisolone, a corticosteroid medicine. It works by suppressing the migration of certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergies and inflammation.

Predoss 1000mg Injection is administered by a doctor in a hospital setting. Do not self-administer. It shows side effects like depression, suicidal thoughts, anxiety, sleeping disorders, difficulty in thinking or being confused, memory loss, hallucinations (seeing or hearing things that do not exist), and feeling high (mania) or mood swings. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects are persistent, consult your doctor.

Inform your doctor before receiving Predoss 1000mg Injection if you are allergic to corticosteroids or methylprednisolone, if you just had a vaccination or have a vaccination planned, or if you have a viral infection such as measles or chickenpox, shingles, or any other medical condition. Stay away from people who have chickenpox or shingles. Consult your doctor immediately if you come into contact with chickenpox or shingles patients. If you are pregnant or breastfeeding and suspect pregnancy or planning pregnancy, inform your doctor before receiving this medicine. Predoss 1000mg Injection is generally not recommended for use in children as it may delay growth and development and cause severe headaches with blurred vision or temporary visual problems in children. Your paediatrician may weigh the benefits and risks before prescribing this medicine to your child.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Predoss 1000mg Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Predoss 1000mg Injection plays a vital role in treating a wide range of allergic reactions and inflammation in the body by blocking certain chemical messengers known as 'histamine,' which is naturally involved in allergic reactions. Predoss 1000mg Injection is accepted to treat various medical conditions such as allergies, joint inflammation (arthritis, golfer's elbow), breathing problems (e.g., asthma), and intestinal problems (e.g., ulcerative colitis, inflammatory bowel disease). Take this medicine for the duration prescribed by your doctor for its maximum benefits.

How Predoss 1000mg Injection Works

Predoss 1000mg Injection contains methylprednisolone, a corticosteroid medicine. It works by suppressing the migration of certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergies and inflammation.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Predoss 1000mg Injection

Predoss 1000mg Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of this medicine may cause elevated blood pressure, retention of salt and water can result in swelling in your feet, legs, or arms, low blood potassium levels, which can lead to fatigue, cramping in the muscles, and weakness. Your doctor may take immediate necessary measures if an overdose is suspected.

Drug Warnings

Inform your doctor if you are allergic to steroids, methylprednisolone, or any components present in the Predoss 1000mg Injection. Inform your doctor if you are pregnant or breastfeeding before receiving Predoss 1000mg Injection. Your doctor will weigh the benefits and potential risks before prescribing Predoss 1000mg Injection for you. Let your doctor know if you have bipolar disorder or depression, tuberculosis, diabetes, epilepsy, glaucoma, osteoporosis, myasthenia gravis (muscle weakness), stomach ulcers, high blood pressure or heart failure, liver or kidney problems or any viral infections or if you are about to undergo an organ transplantation procedure. Predoss 1000mg Injection is generally not recommended for use in children because it can cause growth and development delays as well as severe headaches with blurred vision or temporary visual problems. Individuals with poor immune systems should not take any live vaccinations while taking this medicine. It is safe to take killed vaccinations or toxoids (inactivated toxins), as their effects may be limited.

Drug-Drug Interactions

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MethylprednisoloneMifepristone
Critical
MethylprednisoloneIohexol
Critical

Drug-Drug Interactions

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MethylprednisoloneMifepristone
Critical
How does the drug interact with Predoss 1000mg Injection:
When Predoss 1000mg Injection is taken with Mifepristone, it may decrease the levels of Predoss 1000mg Injection, which may be less effective in treating your condition.

How to manage the interaction:
Taking Predoss 1000mg Injection with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneIohexol
Critical
How does the drug interact with Predoss 1000mg Injection:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Predoss 1000mg Injection with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneVigabatrin
Critical
How does the drug interact with Predoss 1000mg Injection:
Co-administration of Predoss 1000mg Injection and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Predoss 1000mg Injection with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneClarithromycin
Severe
How does the drug interact with Predoss 1000mg Injection:
Taking Clarithromycin with Predoss 1000mg Injection together may significantly increase the blood levels of Predoss 1000mg Injection.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Predoss 1000mg Injection if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneCeritinib
Severe
How does the drug interact with Predoss 1000mg Injection:
Taking Predoss 1000mg Injection with ceritinib may significantly increase the blood levels of Predoss 1000mg Injection.

How to manage the interaction:
Although taking Predoss 1000mg Injection and ceritinib together can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience swelling, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneInfliximab
Severe
How does the drug interact with Predoss 1000mg Injection:
The combined use of Infliximab with Predoss 1000mg Injection can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Predoss 1000mg Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a serious infection, sepsis, complications, fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
MethylprednisoloneCiprofloxacin
Severe
How does the drug interact with Predoss 1000mg Injection:
Coadministration of ciprofloxacin with Predoss 1000mg Injection can increase the risk of tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(an injury that is usually painful and likely to affect your ability to walk).

How to manage the interaction:
Although there is an interaction, Predoss 1000mg Injection can be taken with Ciprofloxacin if prescribed by the doctor. However, if you experience any symptoms such as pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneTofacitinib
Severe
How does the drug interact with Predoss 1000mg Injection:
Using tofacitinib together with Predoss 1000mg Injection may increase the risk of serious infections.

How to manage the interaction:
Although taking Predoss 1000mg Injection and Tofacitinib together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or bleeding, consult the doctor. Do not stop using any medications without a doctor's advice.
MethylprednisoloneThalidomide
Severe
How does the drug interact with Predoss 1000mg Injection:
Taking Thalidomide together with Predoss 1000mg Injection may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Predoss 1000mg Injection together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneRitonavir
Severe
How does the drug interact with Predoss 1000mg Injection:
Taking Predoss 1000mg Injection with ritonavir may significantly increase the blood levels of Predoss 1000mg Injection.

How to manage the interaction:
Although taking Predoss 1000mg Injection and Ritonavir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience swelling, palpitations, sweating, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, menstrual irregularities, or excessive growth of facial or body hair contact a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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METHYLPREDNISOLONE-1000MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLPREDNISOLONE-1000MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Predoss 1000mg Injection with Grapefruit may increase the blood level of Predoss 1000mg Injection. Avoid consuming Grapefruit and Grapefruit juice while taking Predoss 1000mg Injection.

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, tomatoes, cherries, squash, and bell peppers are high in antioxidants.
  • Consuming probiotic-rich foods aids in the development of the immune system's resistance to allergies.
  • Consume foods that are rich in quercetin (a flavonoid), such as apples, cherries, spinach, broccoli, and blueberries.
  • Include seasonal fruits, vegetables, whole grains, healthy fats, and fish in your daily diet.
  • Limit your intake of foods that may cause allergies, such as dairy products, soy, eggs, and nuts.
  • Limit the consumption of foods high in sugar that may aggravate inflammation.
  • Reducing stress and having a regular sleep schedule might be beneficial.
  • Avoid processed meats, refined carbohydrates, sugar, trans fats, and alcohol, as they may aggravate inflammation.

Habit Forming

No

Therapeutic Class

CORTICOSTEROIDS

Predoss 1000mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

No interaction was found. However, limit alcohol consumption as a precautionary measure.

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Pregnancy

Caution

Inform your doctor if you are pregnant or suspect or planning pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Predoss 1000mg Injection.

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Breast Feeding

Safe if prescribed

Predoss 1000mg Injection is considered safe to be used during breastfeeding. If you are breastfeeding, inform your doctor before receiving this injection. Your doctor will weigh the benefits and potential risks before prescribing Predoss 1000mg Injection.

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Driving

Caution

Predoss 1000mg Injection has no or insignificant effect on one's ability to drive or operate machinery. In rare cases, Predoss 1000mg Injection may cause blurred vision or other visual disturbances. If you experience these symptoms, do not drive or operate machinery until you are alert.

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Liver

Caution

If you have a history of liver diseases/conditions or ongoing liver conditions, inform your doctor before receiving Predoss 1000mg Injection. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

If you have a history of kidney diseases/conditions or ongoing kidney conditions, inform your doctor before receiving Predoss 1000mg Injection. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Predoss 1000mg Injection is generally not recommended for use in children because it can delay growth and development as well as severe headaches with blurred vision or temporary visual problems. Before prescribing this medication to your child, your paediatrician may weigh the benefits and risks.

Have a query?

FAQs

Predoss 1000mg Injection belongs to the corticosteroid drug class. It is used to treat symptoms associated with allergic reactions or inflammatory conditions. It is primarily used to treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons.

Predoss 1000mg Injection contains the corticosteroid medication methylprednisolone. It works by blocking the transmission of certain chemical messengers in the body that cause inflammation and allergic reactions, effectively treating a variety of medical conditions associated with allergic and inflammatory reactions.

Corticosteroid medications such as Predoss 1000mg Injection can alter how your body processes carbs and sugars (glucose). They can elevate your blood sugar by preventing insulin from working. If you have diabetes, your blood glucose levels need to be monitored regularly while you are on treatment with this medicine.

Predoss 1000mg Injection is not recommended for treating viral infections such as measles, chickenpox, shingles, or any other viral conditions.

Complete the entire course of treatment with Predoss 1000mg Injection even if you feel better after receiving a few doses, as abrupt stopping may lead to undesirable effects.

While taking Predoss 1000mg Injection, do not receive a "live" vaccine (including measles, mumps, polio, chickenpox) as the vaccine may not work, and you may develop the disease again.

Country of origin

India
Other Info - PR72381

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 17, 2025 | 10:57 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.6701.pdf
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