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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is used in the treatment of neuropathic pain. It contains Pregabalin and Methylcobalamin, which decreases the pain signals and helps rejuvenate and protect damaged nerve cells. It may cause common side effects such as dizziness, drowsiness, headache, loss of appetite, nausea or vomiting, diarrhea, headache, vision problems, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Qura Plus Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

You should take this medicine as prescribed by your doctor. The common side-effects of Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.

Do not take Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse.  It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may cause dizziness or drowsiness. Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor. 

Uses of Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is used in the treatment of Neuropathic pain. The detailed uses of Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule are as follows:
•Anxiety Relief: Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule known is to help reduce anxiety and tension, fostering a sense of calm and relaxation.
•Pain Management: Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may provide effective relief from various types of pain, including headaches and muscle discomfort.
•Sleep Aid: Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule can be beneficial for individuals experiencing sleep disturbances, helping to enhance sleep quality and duration.
•Mood Stabilization: Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may assist in managing mood swings and supporting individuals with depressive symptoms, promoting emotional balance.
•Neuropathic Pain Relief: Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule helps reduce nerve pain by calming overactive nerves and supports nerve repair and regeneration.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule helps in providing relief from neuropathic pain and improved nerve signal conduction.  

 

How Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule Works

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule

Do not take more than the prescribed dose of Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may need a change in diabetic medicines. If you notice decreased urination while taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule , inform your doctor as Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule . In such cases, inform your doctor immediately.  

Drug-Drug Interactions

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PregabalinSodium oxybate
Severe
PregabalinRemifentanil
Severe

Drug-Drug Interactions

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PregabalinSodium oxybate
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Sodium oxybate together with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
PregabalinRemifentanil
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinBuprenorphine
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinPentazocine
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTramadol
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
When Tramadol is used with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Although taking tramadol and Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinEsketamine
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
When Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule and Esketamine are taken together, it may increase the risk of side effects.

How to manage the interaction:
Although taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTapentadol
Severe
How does the drug interact with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule 75 mg and Methylcobalamin 750 mcg Capsule:
Using Tapentadol together with Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain.

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

 

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule Substitute

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  • Neugaba M 75 mg Capsule 15's

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  • Pregalin M 75 Capsule 15's

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  • Maxgalin M 75 Capsule 15's

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  • Venerva 750 mcg/75 mg Tablet 10's

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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side-effects.

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Pregnancy

Unsafe

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is a category C medicine. It is not recommended for use in pregnant women unless the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule should be used with caution in breastfeeding mothers unless the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may cause dizziness and drowsiness. So, avoid driving or operating heavy machinery while using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule .

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Liver

Caution

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule should be used with caution in patients with kidney diseases. Dose adjustments may be necessary

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Children

Unsafe

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is not recommended for anyone below the age of 18 years.

FAQs

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is used in the treatment of neuropathic pain, a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule block the brain's pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule should be stopped gradually over a minimum of 1 week.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule . Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule .

You may notice pain improvement within 2-3 days after taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule . However, it may take 2-3 months for your symptoms to improve depending on your health condition.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may increase your appetite, which might make you eat more, and thus increases the risk of weight gain. However, it’s easier to prevent weight gain than losing the weight. Try to eat a healthy balanced diet. Avoid consuming high-calorie foods, such as soft drinks, chips, oily food, biscuits, cakes, and sweets. If you feel hungry between meals, do not eat junk food, instead eat vegetables, fruits, and low-calorie foods. Regular exercise helps to prevent weight gain. If you still have any concerns, discuss with your doctor.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.

Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule may show an initial benefit after 2 weeks of taking it. However, for full benefits, it may take around 2 to 3 months or more (in some patients).

If you forget to take a dose of Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.

You are advised to avoid alcohol consumption while taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule as it may increase the risk of side effects. However, if you have any concerns, please discuss with your doctor.

If you have started taking Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule , you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.

Store Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule at room temperature in a cool place. Protect from light and moisture. Keep it out of reach of children.

The side effects of Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule include nausea, vomiting, headache, dizziness, drowsiness, increased appetite, weight gain and vision problems. If these side effects persist or worsen, please consult your doctor.

You are recommended to take Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule only if it is advised by your doctor. Therefore, if you are pregnant or planning pregnancy, take your doctor’s advice.

You are recommended to avoid driving or using any tools or machines until you know how Pregabalin 75 mg and Methylcobalamin 750 mcg Capsule affects you as it may cause dizziness or drowsiness in some people.

Country of origin

India

Manufacturer/Marketer address

6, Qura Plus Pharma, Lawspet, Rajaji Nagar, 4Th Cross Street, Pondicherry, Puducherry
Other Info - PRE1200

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