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  3. Premarin Tablet 28's

Premarin Tablet 28's, Pack of 28 TABLETS
Premarin Tablet 28's, Pack of 28 TABLETS
Premarin Tablet 28's, Pack of 28 TABLETS
Premarin Tablet 28's, Pack of 28 TABLETS
Premarin Tablet 28's, Pack of 28 TABLETS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Premarin Tablet is used as hormone replacement therapy to treat symptoms and conditions associated with menopause. It contains conjugated estrogens, which works by replacing the estrogen hormone in menopausal women. It also regulates the secretions of hormones such as luteinizing hormone (LH) (necessary for sexual function and the menstrual cycle) and follicle-stimulating hormone (FSH) (regulates the menstrual cycle). These effects help to improve the symptoms of menopause. It may cause certain side effects such as abnormal vaginal bleeding or spotting, vaginal discharge, pain and swelling in the breasts, discharge from the nipples, changes in breast tissue, feeling or being sick, bloating, abdominal pain, headache, dizziness, mood changes, irritability, joint pain, leg cramps, increased or decreased libido (sexual desire), swelling of face or ankles, rashes on the skin, changes in hair growth, eye, weight and triglyceride levels (fats), intolerance to glucose, memory loss and jaundice (yellowing of the skin or eyes).
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Composition :

CONJUGATED ESTROGENS-0.625MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Premarin Tablet

Premarin Tablet belongs to the class of hormones used as ‘hormone replacement therapy’ to treat symptoms and conditions associated with menopause. During menopause, estrogen levels decrease, leading to hot flushes (feeling of heat over the face, neck, and chest). Women with menopause are at risk of developing osteoporosis (thinning of bones). Premarin Tablet can be used to prevent osteoporosis after menopause.

Premarin Tablet contains ‘conjugated estrogens’, which is used as hormone replacement therapy (HRT). It works by replacing the estrogen hormone in menopausal women. It also regulates the secretions of hormones such as luteinizing hormone (LH) (necessary for sexual function and the menstrual cycle) and follicle-stimulating hormone (FSH) (regulates the menstrual cycle). These effects help to improve the symptoms of menopause.

Premarin Tablet should be taken as advised by your doctor. The dose of medicine and duration of treatment will be decided by the doctor based on your medical condition. Premarin Tablet may cause certain side effects such as abnormal vaginal bleeding or spotting, vaginal discharge, pain and swelling in the breasts, discharge from the nipples, changes in breast tissue, feeling or being sick, bloating, abdominal pain, headache, dizziness, mood changes, irritability, joint pain, leg cramps, increased or decreased libido (sexual desire), swelling of face or ankles, rashes on the skin, changes in hair growth, eye, weight and triglyceride levels (fats), intolerance to glucose, memory loss and jaundice (yellowing of the skin or eyes).

Premarin Tablet should be avoided if you have a history of breast cancer, endometrial cancer (cancer of the lining of the womb), unexplained vaginal bleeding, untreated endometrial hyperplasia (thickening of the womb lining), have a blood clot in the veins (thrombosis), in the legs (deep vein thrombosis) or the lungs (pulmonary embolism), blood clotting disorder, heart attack or angina (chest pain), inherited porphyria (a blood disorder) or liver disease. It is not recommended for use in pregnant and breastfeeding women. Stop taking Premarin Tablet and consult your doctor immediately if you are allergic to it or if you develop jaundice (yellowing of the skin and eyes), high blood pressure and migraine-like headache, become pregnant or notice signs of a blood clot such as redness, swelling and pain in the legs, sudden chest pain or difficulty in breathing. Inform your doctor if you have any intolerance to sugar.

Uses of Premarin Tablet

Treatment of Menopause

Directions for Use

• Premarin Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Premarin Tablet as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Premarin Tablet contains ‘conjugated estrogens’, which is used for hormone replacement therapy (HRT). In menopause, estrogen levels become too low, so Premarin Tablet works by replacing this hormone.  It also regulates the secretions of other hormones from the pituitary gland, such as luteinizing hormone (LH) (necessary for sexual function and the menstrual cycle) and follicle-stimulating hormone (FSH) (regulates the menstrual cycle). These effects help to reduce the symptoms of menopause.

How Premarin Tablet Works

Premarin Tablet contains ‘conjugated estrogens’, which is used as hormone replacement therapy (HRT). It works by replacing the estrogen hormone in menopausal women. It also regulates the secretions of hormones such as luteinizing hormone (LH) (necessary for sexual function and the menstrual cycle) and follicle-stimulating hormone (FSH) (regulates the menstrual cycle). These effects help to improve the symptoms of menopause.

Storage

Keep Premarin Tablet out of sight and reach of children.

What if I have taken an overdose of Premarin Tablet

Do not take more than the prescribed dose of Premarin Tablet as it may cause overdose. The symptoms of overdose include stomach pain, vomiting, nausea, breast tenderness, overtiredness, and withdrawal bleeding may occur in women. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before starting treatment with Premarin Tablet , inform your doctor if you are allergic to it. Also inform if you have fibroids inside the womb, growth of womb lining outside the womb (endometriosis), excessive thickening of the womb lining (endometrial hyperplasia), increased risk of developing blood clots, increased risk of getting estrogen-sensitive cancer (in people with a family history of breast cancer), high blood pressure, diseases associated with liver, kidney, or heart, fluid retention (oedema), diabetes, gallbladder stones, migraine or severe headache, systemic lupus erythematosus, epilepsy (fits), asthma, osteosclerosis (a condition affecting eardrum and hearing), hypocalcemia (low calcium levels in the blood), and high levels of fat in the blood. Premarin Tablet increases the risk of endometrial hyperplasia and endometrial cancer, so your doctor may prescribe you the hormonal medicine ‘progesterone’ to minimize this risk. Inform your doctor if you are pregnant or breastfeeding, as Premarin Tablet is not recommended for use in such a population. Long-term use of high dosages of this medication may raise your risk of heart attack, stroke, blood clots, dementia, breast cancer, or uterine cancer. Discuss this risk with your doctor. If you still have your uterus (womb), see your doctor about whether you should take progestin.

Diet & Lifestyle Advise

  • Wear loose, layered clothing during the nighttime, especially in warm weather. This prevents hot flushes.
  • Manage your weight. Shed excess weight by exercising regularly if you are obese or overweight. 
  • Talk to a psychologist if you feel low, sad, isolated, or have any sleeping issues.
  • Apply moisturizers to prevent skin dryness.
  • Limit alcohol intake and quit smoking.
  • Try to eat foods that are rich in iron and Vitamin C, including red meat, shellfish, eggs, beans, and leafy green vegetables.

Habit Forming

No

Therapeutic Class

HORMONES

Premarin Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Consumption of alcohol while using this medicine may cause interactions. Discuss with your doctor for more information.

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Pregnancy

Unsafe

Premarin Tablet is a category X drug. This medicine is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor. Your doctor may prescribe an alternative based on your medical condition.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and reduce the production of milk. Hence, inform your doctor before starting treatment with Premarin Tablet if you are breastfeeding. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Safe

Premarin Tablet may not affect your ability to drive.

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Liver

Unsafe

Premarin Tablet should not be used in patients with liver diseases. Hence inform your doctor if you have/had a history of liver disease before starting treatment with this medicine.

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Kidney

Caution

Premarin Tablet should be used with caution in patients with severe kidney diseases. Hence If you have a pre-existing or a history of kidney disease, inform your doctor before taking Premarin Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

The safety of Premarin Tablet in children is not established. Hence, the use is not recommended.

Have a query?

FAQs

Premarin Tablet is used as hormone replacement therapy to treat symptoms and conditions associated with menopause.

Premarin Tablet works by replacing the deficient estrogen hormone in menopausal women. It effectively reduces the symptoms and improves health conditions.

Premarin Tablet is not a form of contraception. Because pregnancy is possible early in menopause while you are still experiencing monthly cycles, you should consult with your doctor about another (non-hormonal) type of birth control.

Your doctor decides the dose of Premarin Tablet based on your health condition. It is advised not to take more than the recommended dose.

Premarin Tablet may cause weight changes. Premarin Tablet contains 'conjugated estrogen' that regulates metabolism and body weight. However, exercise regularly and eat a well-balanced diet to control body weight. In case of unusual weight gain, consult your doctor.

Premarin Tablet increases the risk of breast cancer when it is used as Hormonal replacement therapy for longer durations.

You are not recommended to stop taking Premarin Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Premarin Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Premarin Tablet , please consult your doctor.

When estrogen combined with smoking increases the risk of blood clots, heart attacks, high blood pressure, and strokes, especially in women over the age of 35, so you should avoid smoking and using tobacco. Take sun protection by using appropriate precautions such as using sunscreens and shades. Be cautious of any adverse effects and report them to your doctor right away.

There is no documented evidence available as of now. If you are concerned about weight loss or if you experience any drastic changes in weight loss, seek medical attention.

Usually, Premarin Tablet is taken once daily. The dosage may vary depending on the disease being treated and person to person. It is important to follow your doctor's medication instructions.

Premarin Tablet is a mixture of estrogen hormones, derived from the urine of pregnant mares or synthetically derived from plant materials.

If you were experiencing menoporosis (bone thinning) or menopause symptoms and disorders (menstrual periods ending permanently). In that case, your doctor may prescribe this medication to you. Take this medication orally as your physician prescribes, with or without a meal.

Do not miss your medication as per instructions. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. If it is almost time for your next dose, skip it and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Common side effects of Premarin Tablet may include, abnormal vaginal bleeding or spotting, vaginal discharge, pain and swelling in the breasts, discharge from the nipples, changes in breast tissue, feeling or being sick, bloating, abdominal pain, headache, dizziness, mood changes, irritability, joint pain, leg cramps, increased or decreased libido (sexual desire), swelling of face or ankles, rashes on the skin, changes in hair growth, eye, weight and triglyceride levels (fats), intolerance to glucose, memory loss and jaundice (yellowing of the skin or eyes).

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ?G? Block , Bandra Kurla Complex, Bandra East , Mumbai ? 400051.
Other Info - PRE0263

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:40 AM IST

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Reference

  1. https://www.mayoclinic.org/drugs-supplements/conjugated-estrogens-oral-route/description/drg-20075319#:~:text=Conjugated%20estrogens%20are%20a%20medicine,amounts%20of%20estrogen%20(hypoestrogenism).
  2. https://www.mayoclinic.org/drugs-supplements/conjugated-estrogens-oral-route/side-effects/drg-20075319?p=1
  3. https://www.rxlist.com/premarin-drug.htm
  4. https://www.cigna.com/knowledge-center/hw/medications/conjugated-estrogens-d00541a1
  5. https://www.news-medical.net/drugs/Premarin.aspx

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