Pyrodex 20 Tablet 10's
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About Pyrodex 20 Tablet
Pyrodex 20 Tablet is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Osteoarthritis is a degenerative joint disease caused by the breakdown of cartilage (a protective covering) and the underlying bone.
Pyrodex 20 Tablet contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins.
In some cases, you may experience common side effects, such as diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Most of these side effects do not require medical attention. However, speak to your doctor if you experience these side effects persistently.
Do not take Pyrodex 20 Tablet if you are allergic to any of its ingredients or have a history of an asthma attack or severe allergic reaction to NSAIDs. Consult your doctor before taking Pyrodex 20 Tablet if you are pregnant or planning to become pregnant. Pyrodex 20 Tablet is not recommended for children under 18 years, as its safety and efficacy have not been established.
Uses of Pyrodex 20 Tablet
Pyrodex 20 Tablet is used to treat joint pain and inflammation associated with various conditions. The detailed uses of Pyrodex 20 Tablet are as follows:
- Rheumatoid Arthritis: It helps reduce inflammation and joint damage caused by autoimmune activity.
- Osteoarthritis: It helps relieve joint pain, inflammation, and stiffness caused by cartilage wear and tear.
- Ankylosing Spondylitis: It helps alleviate spinal pain and stiffness associated with this chronic inflammatory disease.
- Menstrual Pain (Dysmenorrhea) Management: It can effectively relieve pain caused by menstrual cramps, providing comfort during menstruation (periods).
- Postoperative Pain Management: It is often prescribed for short-term pain and inflammation management following surgical procedures.
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Directions for Use
- Pyrodex 20 Tablet can be taken with or without food. However, taking it after food may help reduce stomach upset.
- It is usually taken 1-2 times daily at the same time each day or as prescribed by your doctor.
- Swallow it as a whole with a glass of water.
- Do not crush, chew, break, or open the medication.
Medicinal Benefits
- Pyrodex 20 Tablet belongs to the group of painkillers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
- Pyrodex 20 Tablet is used to relieve symptoms associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, such as stiffness, swelling, and joint pain.
- Pyrodex 20 Tablet contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins.
- Prostaglandins are produced at injury sites and cause pain and swelling.
- By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.
How Pyrodex 20 Tablet Works
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- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- Get help from a health care professional.
- Manage your feelings and things that trigger them.
- Fuel your body with good food like fruits, veggies, and whole grains.
- Find calm through activities like meditation or yoga.
- Work on changing negative patterns and thoughts.
- Focus on being healthy overall, not just how you look.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
What if I have taken an overdose of Pyrodex 20 Tablet
Drug Warnings
- Do not take Pyrodex 20 Tablet if you are allergic to any of its ingredients or have a history of an asthma attack or severe allergic reaction to NSAIDs.
- Pyrodex 20 Tablet may increase the risk of serious heart-related problems, like heart attack and stroke.
- It may also cause stomach and intestinal bleeding/ulcers. So, inform your doctor if you have any heart or stomach problems before taking Pyrodex 20 Tablet .
- Avoid taking Pyrodex 20 Tablet if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG), as it can increase your risk of a heart attack or stroke.
- Consult your doctor before taking Pyrodex 20 Tablet if you are pregnant or planning to become pregnant.
- Avoid breastfeeding while taking Pyrodex 20 Tablet , as it can pass into breast milk.
- Pyrodex 20 Tablet is not recommended for children under 18 years, as its safety and efficacy have not been established.
- Pyrodex 20 Tablet may cause drowsiness, dizziness, and vision problems, so drive with caution.
- Avoid consuming alcohol along with Pyrodex 20 Tablet , as it may increase drowsiness and the risk of stomach bleeding.
- Inform your doctor before taking Pyrodex 20 Tablet if you have asthma, water retention (oedema), hypertension (high blood pressure), diabetes (high blood sugar), high cholesterol, blood clots, or liver/kidney disease.
Drug-Drug Interactions
Drug-Drug Interactions
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Using ketorolac tromethamine together with Pyrodex 20 Tablet may increase the risk of side effects.
How to manage the interaction:
Taking Pyrodex 20 Tablet with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
Co-administration of Cidofovir with Pyrodex 20 Tablet can increase the risk of kidney problems.
How to manage the interaction:
Taking Pyrodex 20 Tablet with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Using deferasirox together with Pyrodex 20 Tablet may increase the risk of ulcers.
How to manage the interaction:
Co-administration of Pyrodex 20 Tablet with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Sirolimus with Pyrodex 20 Tablet can increase the risk or severity of kidney damage.
How to manage the interaction:
Co-administration of Sirolimus with Pyrodex 20 Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medication without consulting your doctor.
Using captopril together with Pyrodex 20 Tablet may reduce the effects of captopril in lowering blood pressure, they may also result in kidney problems.
How to manage the interaction:
Taking Pyrodex 20 Tablet with Captopril together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Pyrodex 20 Tablet and Lomitapide may increase the risk of liver injury.
How to manage the interaction:
There may be a possibility of interaction between Pyrodex 20 Tablet and Lomitapide, but it can be taken if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Taking tacrolimus with Pyrodex 20 Tablet may increase risk of kidney problems.
How to manage the interaction:
Although taking tacrolimus and Pyrodex 20 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Coadministration of Mefenamic acid with Pyrodex 20 Tablet can increase the risk side effects such as inflammation(swelling with redness and pain), bleeding, ulceration, and perforation leading to serious blood loss.
How to manage the interaction:
Taking Mefenamic acid with Pyrodex 20 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Pyrodex 20 Tablet with Dabigatran etexilate can increase the risk of bleeding.
How to manage the interaction:
There may be a possibility of interaction between Pyrodex 20 Tablet and Dabigatran etexilate, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Pyrodex 20 Tablet with Ramucirumab can increase the risk of bleeding.
How to manage the interaction:
Taking Pyrodex 20 Tablet with Ramucirumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Performing yoga may also help improve joint flexibility and pain.
- Maintain a healthy weight by engaging in regular low-impact exercises and consuming a balanced diet.
- Get adequate sleep, as rest can help reduce inflammation and swelling.
- Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
- De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
- Acupuncture, massage, and physical therapy may also be helpful.
- Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
- Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
- Avoid smoking and alcohol consumption.
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Alcohol
Unsafe
Avoid alcohol consumption while taking Pyrodex 20 Tablet , as it may cause increased dizziness and drowsiness. It may also cause an increase in the risk of stomach/intestinal ulcers and bleeding.
Pregnancy
Caution
Avoid taking Pyrodex 20 Tablet if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe Pyrodex 20 Tablet only if the benefits outweigh the risks. Do not take Pyrodex 20 Tablet in the last 20 weeks of pregnancy, as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.
Breast Feeding
Unsafe
Pyrodex 20 Tablet can pass into breast milk. So, avoid breastfeeding while taking Pyrodex 20 Tablet . Please consult your doctor if you have any concerns regarding this.
Driving
Unsafe
Pyrodex 20 Tablet may cause drowsiness, dizziness, and vision problems. Do not drive or operate heavy machinery unless you are alert.
Liver
Caution
Dose adjustment may be needed. Pyrodex 20 Tablet should be used with caution in patients with liver impairment/liver disease.
Kidney
Caution
Dose adjustment may be needed. Pyrodex 20 Tablet should be used with caution in patients with kidney impairment/kidney disease.
Children
Unsafe
Pyrodex 20 Tablet is not recommended for children under 18 years, as its efficacy and safety have not been established.
Heart
Pyrodex 20 Tablet may increase the risk of heart attack or stroke. Do not use Pyrodex 20 Tablet immediately before or after bypass surgery. Inform your doctor if you have a history of heart disease or other heart problems.
Geriatrics
Caution
Pyrodex 20 Tablet may be used in geriatric patients, but only with caution and close medical supervision due to its long half-life and increased risk of serious side effects.
FAQs
Pyrodex 20 Tablet is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Pyrodex 20 Tablet works by blocking the effect of chemical messengers (prostaglandin), thereby reducing joint pain, stiffness, swelling, and inflammation.
Diarrhoea might be a side effect of Pyrodex 20 Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not take Pyrodex 20 Tablet for longer durations or high doses as it may cause unpleasant side effects. Do not exceed the dose and duration prescribed by your doctor.
Pyrodex 20 Tablet may increase the risk of heart attack or stroke. Do not use Pyrodex 20 Tablet within 1 week before or after bypass surgery. Inform your doctor if you have a history of heart disease or other heart problems.
Consult your doctor before taking Pyrodex 20 Tablet if you have diabetes, as Pyrodex 20 Tablet might increase your blood sugar levels.
The common side effects of Pyrodex 20 Tablet are diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/018147s029lbl.pdf
- https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/a_v7/SmPc-PIROXICAM.pdf
- https://www.medicines.org.uk/emc/files/pil.14311.pdf
- https://www.drugs.com/mtm/piroxicam.html
- https://medlineplus.gov/druginfo/meds/a684045.html
- https://www.medindia.net/doctors/drug_information/piroxicam.htm
