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compositionComposition:QUININE-300MG
prescriptionPrescription Medicine
Quinine Dihydrochloride 600 mg Injection 2 ml is used to treat malaria. Quinine Dihydrochloride 600 mg Injection 2 ml contains Quinine, which treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further. Common side effects of Quinine Dihydrochloride 600 mg Injection 2 ml are injection site reactions, nausea, restlessness, visual disturbances, vertigo (sudden internal or external spinning sensation), difficulty hearing or ringing in the ears, confusion and nervousness.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

QUININE-300MG

Manufacturer/Marketer :

Vulcan Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

Quinine Dihydrochloride 600 mg Injection 2 ml belongs to the class of anti-malarial drugs primarily used to treat malaria. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start ten days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools. Quinine Dihydrochloride 600 mg Injection 2 ml is only used to treat malaria but does not prevent it.

Quinine Dihydrochloride 600 mg Injection 2 ml contains Quinine, which treats malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Quinine Dihydrochloride 600 mg Injection 2 ml will be administered by a qualified healthcare professional; hence do not self-administer. Sometimes, you may experience common side effects like injection site reactions, nausea, restlessness, visual disturbances, vertigo (sudden internal or external spinning sensation), difficulty hearing or ringing in the ears, confusion and nervousness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Quinine Dihydrochloride 600 mg Injection 2 ml should be avoided if you are allergic to it. Let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Quinine Dihydrochloride 600 mg Injection 2 ml will affect your ability to drive or operate machinery; hence, avoid driving or using machinery. It is recommended not to consume any alcoholic beverages to rule out any possibility of side effects.

Uses of Quinine Dihydrochloride 600 mg Injection 2 ml

Quinine Dihydrochloride 600 mg Injection 2 ml is used in the treatment of Malaria. The detailed uses of Quinine Dihydrochloride 600 mg Injection 2 ml are as follows:

  • Treat severe or complicated malaria: Quinine Dihydrochloride 600 mg Injection 2 ml is primarily used as an antimalarial agent in patients who cannot take oral medications due to vomiting, coma, or convulsions. It kills Plasmodium parasites in the bloodstream and helps control life-threatening infections.
  • Alternative to injectable artesunate: In settings where artesunate is unavailable, Quinine Dihydrochloride 600 mg Injection 2 ml serves as a second-line treatment for severe malaria, especially in resource-limited environments.

Key Benefits

Quinine Dihydrochloride 600 mg Injection 2 ml belongs to the class of 'anti-malarial drugs,' containing Quinine, primarily used to treat malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Quinine Dihydrochloride 600 mg Injection 2 ml will be administered by a healthcare professional.
  • Do not self-administer.
Quinine Dihydrochloride 600 mg Injection 2 ml contains Quinine, which treats malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.
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Alcohol

Caution

Avoid alcohol while using Quinine Dihydrochloride 600 mg Injection 2 ml since it can worsen the side effects.

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Pregnancy

Caution

Quinine Dihydrochloride 600 mg Injection 2 ml is not recommended for use in pregnancy unless clearly necessary. Hence, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Quinine Dihydrochloride 600 mg Injection 2 ml.

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Breast Feeding

Caution

Quinine Dihydrochloride 600 mg Injection 2 ml is not recommended for use while breastfeeding unless clearly necessary. So, inform your doctor if you are a breastfeeding mother. Your doctor will weigh the benefits and potential risks before prescribing Quinine Dihydrochloride 600 mg Injection 2 ml.

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Driving

Caution

Quinine Dihydrochloride 600 mg Injection 2 ml may affect your ability to drive or operate machinery. Hence, avoid driving or using machinery until you are alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using the Quinine Dihydrochloride 600 mg Injection 2 ml. Your doctor may suggest tests for monitoring your liver function while on treatment with Quinine Dihydrochloride 600 mg Injection 2 ml.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using the Quinine Dihydrochloride 600 mg Injection 2 ml. Your doctor may suggest tests for monitoring your liver function while on treatment with Quinine Dihydrochloride 600 mg Injection 2 ml. Dose adjustments may be necessary based on your condition.

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Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing Quinine Dihydrochloride 600 mg Injection 2 ml. The dose of this medicine will be decided by your doctor based on the age and condition of your child.

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Heart

Caution

Quinine Dihydrochloride 600 mg Injection 2 ml can affect heart rhythm and worsen existing cardiac conditions, so it's risky for heart patients. Always consult your doctor before use to avoid serious complications.

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Geriatrics

Caution

Geriatric patients should receive Quinine Dihydrochloride 600 mg Injection 2 ml only under strict medical supervision. Older adults are more susceptible to side effects like heart rhythm disturbances and low blood sugar, so careful evaluation is essential before use.

As Quinine Dihydrochloride 600 mg Injection 2 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Diet & Lifestyle Advise

  • Eat nutritious food containing proteins and vitamins.
  • Consume light and digestible foods such as soups, gruel, khichadi, and rice.
  • Drink plenty of fluids. Lukewarm water is best as it helps in soothing.
  • Consume fruits rich in vitamins A and C, such as lemon, grapes, beetroot, and carrot.
  • Avoid high-fibre foods, fatty foods, junk foods, and caffeine.
  • Spray insecticides at home and outside to prevent mosquito breeding.
  • Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/sprays.
  • Avoid alcohol, coffee, tea, carbonated beverages, and spicy food.

Have a query?

Drug Warnings

Before starting treatment with Quinine Dihydrochloride 600 mg Injection 2 ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you are pregnant, planning to conceive or a nursing mother. And also, let your doctor know before administrating Quinine Dihydrochloride 600 mg Injection 2 ml if you have myasthenia gravis (muscle disorders), optic neuritis (Inflammation of the optic nerve), prolonged QT interval or Glucose-6-phosphate Dehydrogenase (G6PD) deficiency. Avoiding alcohol is recommended to rule out any possibility of side effects. Quinine Dihydrochloride 600 mg Injection 2 ml may cause visual disturbances and vertigo (sudden internal or external spinning sensation); thus, patients should be cautioned not to drive or operate machinery if affected.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Co-administration of Quinine Dihydrochloride 600 mg Injection 2 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Quinine Dihydrochloride 600 mg Injection 2 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Taking Alfuzosin and Quinine Dihydrochloride 600 mg Injection 2 ml can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alfuzosin and Quinine Dihydrochloride 600 mg Injection 2 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Taking Lidocaine with Quinine Dihydrochloride 600 mg Injection 2 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Lidocaine and Quinine Dihydrochloride 600 mg Injection 2 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Taking Bupivacaine and Quinine Dihydrochloride 600 mg Injection 2 ml may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking bupivacaine and Quinine Dihydrochloride 600 mg Injection 2 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Taking Ceritinib with Quinine Dihydrochloride 600 mg Injection 2 ml may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Quinine Dihydrochloride 600 mg Injection 2 ml together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Coadministration of Quinine Dihydrochloride 600 mg Injection 2 ml and erythromycin may significantly increase the blood levels and effects of Quinine Dihydrochloride 600 mg Injection 2 ml

How to manage the interaction:
Although taking erythromycin and Quinine Dihydrochloride 600 mg Injection 2 ml together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience headache, flushing, sweating, nausea, vomiting, diarrhoea, stomach pain, dizziness, ringing in the ears, hearing loss, blurred vision, vision loss, and abnormal heart rhythm, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Taking Efavirenz and Quinine Dihydrochloride 600 mg Injection 2 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Quinine Dihydrochloride 600 mg Injection 2 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Using moxifloxacin together with Quinine Dihydrochloride 600 mg Injection 2 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Quinine Dihydrochloride 600 mg Injection 2 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like an irregular heartbeat, heart problems, or feeling dizzy or short of breath, call your doctor right away. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
Taking Pazopanib with Quinine Dihydrochloride 600 mg Injection 2 ml may significantly reduces the blood levels of pazopanib.

How to manage the interaction:
Although there is a interaction between Pazopanib and Quinine Dihydrochloride 600 mg Injection 2 ml, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain or tightness, pain in your arms, back, neck, or jaw, shortness of breath, numbness or weakness on one side of your body, and difficulty speaking. Do not stop using any medications without a doctor's advice.
How does the drug interact with Quinine Dihydrochloride 600 mg Injection 2 ml Dihydrochloride 600 mg Injection 2 ml:
When taken in combination Quinine Dihydrochloride 600 mg Injection 2 ml may significantly raise the loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking loperamide with Quinine Dihydrochloride 600 mg Injection 2 ml together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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[ANTI- MALARIALS]

FAQs

Quinine Dihydrochloride 600 mg Injection 2 ml is used to treat Malaria.

Quinine Dihydrochloride 600 mg Injection 2 ml belongs to the class of anti-malarial drugs, containing Quinine that treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

You should not take Quinine Dihydrochloride 600 mg Injection 2 ml if you have or ever had a heart rhythm disorder called Long QT syndrome, glucose-6-phosphate dehydrogenase deficiency (G-6-PD), myasthenia gravis (a muscle disorder), optic neuritis (inflammation of the nerves in your eyes) if taking Quinine Dihydrochloride 600 mg Injection 2 ml in the past ever caused bleeding.

Quinine Dihydrochloride 600 mg Injection 2 ml can cause a lowering of blood sugar levels. So, if you are diabetic, please inform your doctor before starting treatment with Quinine Dihydrochloride 600 mg Injection 2 ml, and dose adjustment might be required depending upon your medical condition.

Quinine Dihydrochloride 600 mg Injection 2 ml may affect the heart rhythm and cause QT prolongation (heart muscle takes longer than usual to recharge between beats). This QT prolongation can cause a serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases.

Glucose-6-phosphate dehydrogenase deficiency is a hereditary condition that affects red blood cells. A defect in an enzyme called glucose-6-phosphate dehydrogenase in affected individuals causes red blood cells to break down prematurely. It leads to hemolytic anaemia, which happens when red blood cells are destroyed faster than the body can replenish them.

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Other Info - QUI0275
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