Rebopag 75 Tablet 10's

Prescription drug

MRP ₹5343.5

(Inclusive of all Taxes)

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Written By Thota sri Harshini ,

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rebopag 75 Tablet 10's is used to treat low platelet count. It contains Eltrombopag, which works by causing the cells in the bone marrow to produce more platelets. In some cases, this medicine may cause side effects such as nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, and cough. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Rebopag 75 Tablet 10's

Rebopag 75 Tablet 10's is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Rebopag 75 Tablet 10's is also used to treat severe aplastic anemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused by the hepatitis C virus. Severe aplastic anemia is a condition in which the bone marrow doesn't make enough blood cells.

Rebopag 75 Tablet 10's contains Eltrombopag, which belongs to the class of 'thrombopoietin receptor agonists. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Rebopag 75 Tablet 10's works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Rebopag 75 Tablet 10's helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

In some cases, Rebopag 75 Tablet 10's can cause common side effects like nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, anemia (lack of blood cells), cough, and tingling numbness. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Rebopag 75 Tablet 10's or any other medicines before starting Rebopag 75 Tablet 10's. Consult the doctor if you are pregnant or planning to conceive. Rebopag 75 Tablet 10's is not indicated for use in breastfeeding since it passes into the breast milk.

Uses of Rebopag 75 Tablet 10's

Rebopag 75 Tablet 10's is used to treat low platelet count and severe aplastic anemia (SAA). The detailed uses of Rebopag 75 Tablet 10's are as follows:

Chronic immune thrombocytopenia (ITP): Rebopag 75 Tablet 10's helps prevent excessive bleeding in patients with low platelet counts.
Severe aplastic anemia: Rebopag 75 Tablet 10's is used to treat severe aplastic anemia when other treatments have failed.
Chronic hepatitis C-related thrombocytopenia: Rebopag 75 Tablet 10's helps maintain platelet levels before and during interferon therapy.

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Directions for Use

Rebopag 75 Tablet 10's can be taken with or without food.
Follow your doctor's instructions on the dosage and timing of this medication.
Shake well before use. Measure the prescribed dose using a measuring cup and administer it orally.
Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Rebopag 75 Tablet 10's contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections, and severe aplastic anemia (SAA).
Rebopag 75 Tablet 10's works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets.
The increase in these bone marrow cells stimulates the production of platelets.
Thus, Rebopag 75 Tablet 10's prevents bleeding episodes by increasing the number of platelets in the blood.

How Rebopag 75 Tablet 10's Works

Rebopag 75 Tablet 10's contains Eltrombopag, which belongs to the class of 'thrombopoietin receptor agonists. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Rebopag 75 Tablet 10's works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Rebopag 75 Tablet 10's helps increase these bone marrow cells, stimulating the number of platelets and further lowering the risk of bleeding.

Storage

• Store in a cool and dry place away from sunlight.• Keep Rebopag 75 Tablet 10's out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Rebopag 75 Tablet

Flu Symptoms

Get plenty of rest and sleep.
Keep your body warm.
Drink plenty of fluids to stay hydrated.
Avoid strenuous activities.
Maintain good hygiene to prevent flu from spreading.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Joint Pain

Here are the steps to manage Joint Pain caused by medication usage:

Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Depression

Managing depression as a side effect of medication: a comprehensive guide.

Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
Tell your doctor about your depression symptoms to adjust medication.
Consult a therapist or counsel for emotional support.
Engage in regular exercise to release endorphins (neurotransmitters).
Practice stress-reducing techniques like meditation and deep breathing.
Build a support network of friends, family, and support groups.
Establish a consistent sleep schedule.
Eat a nutritious diet rich in fruits, vegetables, and whole grains.
Limit or avoid alcohol and recreational substances.
Keep a mood journal to track symptoms and progress.

Common Cold

Here are the steps to manage the medication-triggered Upper respiratory tract infection:

Inform your doctor about the symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Rebopag 75 Tablet 10's

Take Rebopag 75 Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include rash, slowed heartbeat, and excessive tiredness. It may also cause life-threatening blood clots. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Rebopag 75 Tablet 10's or other medicines, please inform your doctor in advance.
Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Rebopag 75 Tablet 10's.
Take Rebopag 75 Tablet 10's at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Rebopag 75 Tablet 10's.
It is not recommended during pregnancy since it may have harmful effects on the foetus.
Consult your doctor before using Rebopag 75 Tablet 10's if you are a breastfeeding mother.
Do not drive or operate machinery since Rebopag 75 Tablet 10's may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive.
Avoid or limit alcohol consumption with Rebopag 75 Tablet 10's as it may affect the efficacy of Rebopag 75 Tablet 10's.
It is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

Drug-Drug Interactions

EltrombopagMagnesium oxide

Critical

EltrombopagFerrous gluconate

Critical

Drug-Drug Interactions

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EltrombopagMagnesium oxide

Critical

How does the drug interact with Rebopag 75 Tablet:
Coadministration of Magnesium oxide with Rebopag 75 Tablet can impair the absorption of Rebopag 75 Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Rebopag 75 Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

EltrombopagFerrous gluconate

Critical

How does the drug interact with Rebopag 75 Tablet:
Ferrous gluconate can make Rebopag 75 Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Rebopag 75 Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Rebopag 75 Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.

EltrombopagMagnesium citrate

Critical

How does the drug interact with Rebopag 75 Tablet:
Taking magnesium citrate with Rebopag 75 Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Rebopag 75 Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Rebopag 75 Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.

EltrombopagAluminium hydroxide

Critical

How does the drug interact with Rebopag 75 Tablet:
Coadministration of Rebopag 75 Tablet and aluminum hydroxide may interfere with the absorption of Rebopag 75 Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Rebopag 75 Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.

EltrombopagFerric maltol

Critical

How does the drug interact with Rebopag 75 Tablet:
Ferric maltol can make Rebopag 75 Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Rebopag 75 Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Rebopag 75 Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.

EltrombopagCalcium chloride

Critical

How does the drug interact with Rebopag 75 Tablet:
When Rebopag 75 Tablet is mixed with Calcium chloride, the amount of Rebopag 75 Tablet in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Rebopag 75 Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

EltrombopagInterferon alfa-2b

Severe

How does the drug interact with Rebopag 75 Tablet:
When Interferon alfa-2b is taken with Rebopag 75 Tablet, it can lower the metabolism of Rebopag 75 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rebopag 75 Tablet and Interferon alfa-2b, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to call a doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Do not discontinue any medications without consulting a doctor.

EltrombopagInterferon alfa-n1

Severe

How does the drug interact with Rebopag 75 Tablet:
Coadministration of Rebopag 75 Tablet and Interferon alfa-n1 can increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Rebopag 75 Tablet and Interferon alfa-n1 together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.

EltrombopagPeginterferon alfa-2a

Severe

How does the drug interact with Rebopag 75 Tablet:
Combining Rebopag 75 Tablet with Peginterferon alfa-2a can lower the metabolism of Rebopag 75 Tablet. This can increase the risk or severity of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Rebopag 75 Tablet and Peginterferon alfa-2a, but it can be taken if prescribed by a doctor. If you have any of these symptoms like confusion, changes in consciousness, harmful substances in the blood, bleeding from enlarged veins, bleeding, infection of the abdominal wall, complications, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, feeling tired, feeling sick, throwing up, bleeding, pain, dark urine, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.

EltrombopagInterferon alfacon-1

Severe

How does the drug interact with Rebopag 75 Tablet:
Coadministration of Rebopag 75 Tablet and Interferon alfacon-1 can increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Rebopag 75 Tablet and Interferon alfacon-1 together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat natural and healthy foods by cutting down on fatty and sodium-processed foods.
Exercise regularly to maintain good health.
Avoid smoking and alcohol intake.
Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
A high-protein diet, such as lean meat, chicken, crab, turkey, beef, and fish, can help increase platelet count.
Eating Papaya is the best natural remedy to increase your platelet count, and you can also use Papaya leave's mixture.
Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit, and broccoli can also boost your platelet count.

Habit Forming

No

Therapeutic Class

PLATELET STIMULATING AGENTS

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Alcohol

Caution

Limit alcohol intake, along with Rebopag 75 Tablet 10's, to attain the maximum efficacy of Rebopag 75 Tablet 10's and rule out any possibility of worsening of side effects.

Pregnancy

Unsafe

Rebopag 75 Tablet 10's is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.

Breast Feeding

Consult your doctor

It is not known if Rebopag 75 Tablet 10's is excreted into the breast milk. If you are a nursing mother, please consult your doctor for more information before taking Rebopag 75 Tablet 10's.

Driving

Caution

Rebopag 75 Tablet 10's may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Rebopag 75 Tablet 10's. It may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Rebopag 75 Tablet 10's based on your health condition.

Kidney

Caution

Rebopag 75 Tablet 10's should be used with caution in cases of renal impairment. Seek a doctor's advice before starting Rebopag 75 Tablet 10's if you have any kidney problems is advised.

Children

Safe if prescribed

Rebopag 75 Tablet 10's is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

Heart

If you have a heart disease or any related concerns, Please consult your doctor before using Rebopag 75 Tablet 10's.

Geriatrics

Consult your doctor

Please consult your doctor before giving Rebopag 75 Tablet 10's to elderly people.

FAQs

Country of origin

India

Manufacturer/Marketer address

Msn House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, India

Other Info - REB0208

Author Details

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 14, 2025 | 12:50 PM IST

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