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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Regenta Eye/Ear Drops is an antibiotic used to treat eye and ear infections caused by bacteria such as conjunctivitis, keratitis, keratoconjunctivitis, blepharitis, blepharoconjunctivitis, otitis externa (inflammation of the ear), and corneal ulcers. It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection causing bacteria. This medicine is not practical for treating viral infections. Sometimes, you may experience specific common side effects, such as eye discomfort, irritation, eye pain, and a stinging sensation.

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Whats That

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Composition :

GENTAMICIN-0.3%W/V

Manufacturer/Marketer :

Regaine Laboratories

Consume Type :

EYE/EAR

Return Policy :

Not Returnable

Expires on or after :

About Regenta Eye/Ear Drops

Regenta Eye/Ear Drops is an antibiotic medicine that treats bacterial infections of the eye and ear. It is used to treat infections like conjunctivitis (inflammation of the mucous membrane (conjunctiva) of the eye), keratitis (inflammation of the cornea), keratoconjunctivitis (inflammation of conjunctiva and cornea), blepharitis (inflammation of the eyelids), blepharoconjunctivitis (inflammation of conjunctiva and eyelids), corneal ulcers, and otitis externa (inflammation of the ear).

Regenta Eye/Ear Drops is composed of Gentamicin, an aminoglycoside antibiotic. It prevents bacteria from synthesising essential proteins required to carry out vital functions. It has broad-spectrum activity against aerobic Gram-positive and Gram-negative bacteria. 

Regenta Eye/Ear Drops is for external use only. Common side effects of Regenta Eye/Ear Drops, when used as eye drops, include local sensitivity in the eye, irritation, itching, redness, burning or a stinging sensation at the application site, and blurred vision. Side effects of Regenta Eye/Ear Drops, when used as ear drops, include local sensitivity in the ear, burning or stinging sensation, itching, skin inflammation, and vestibular disorder/dizziness. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are allergic to Regenta Eye/Ear Drops or any other medications. Please inform your doctor if you have any liver/kidney diseases, myasthenia gravis (muscle weakness), hearing problems, and a perforated eardrum before using Regenta Eye/Ear Drops. Pregnant and breastfeeding mothers should consult the doctor before starting Regenta Eye/Ear Drops. This medicine may cause temporary blurred vision; hence drive only when you are alert and have clear vision. Avoid or limit alcohol consumption during the treatment since Regenta Eye/Ear Drops may cause dizziness. Regenta Eye/Ear Drops should be used for children only when advised by a doctor.

Uses of Regenta Eye/Ear Drops

Regenta Eye/Ear Drops is used in the treatment of bacterial eye/ear infections. The detailed uses of Regenta Eye/Ear Drops are as follows:
• Bacterial eye infections: Regenta Eye/Ear Drops is used to treat bacterial infections of the eye such as conjunctivitis, keratitis and blepharitis.
• Corneal Ulcers: Regenta Eye/Ear Drops is used to treat corneal ulcers, especially those caused by bacterial infections.
• Post-Surgical Eye Infections: Regenta Eye/Ear Drops may also be used to prevent bacterial infection after eye surgeries or after removal of foreign body from the eye.
• Ear Infections: Regenta Eye/Ear Drops is used to treat bacterial infections of outer ear (otitis externa) or middle ear (otitis media).

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • For Eye: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
  • For Ear: Lie down with the affected ear facing upwards. Hold the dropper over the ear and instil the prescribed number of drops into the ear.
  • Regenta Eye/Ear Drops is for use in eyes/ears only. Not for injection.
  • Once the nozzle is piereced, do not touch the nozzle tip as this may contaminate the solution.

Medicinal Benefits

Regenta Eye/Ear Drops treats various bacterial infections of the eye and ear. Regenta Eye/Ear Drops consists of Gentamicin, an antibiotic that prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Regenta Eye/Ear Drops may also be given as a treatment to prevent infections in the injured eye or ear.

How Regenta Eye/Ear Drops Works

Regenta Eye/Ear Drops is composed of Gentamicin, an aminoglycoside antibiotic. It prevents bacteria from synthesising essential proteins required to carry out vital functions. It has broad-spectrum activity against aerobic Gram-positive and Gram-negative bacteria.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Regenta Eye/Ear Drops

Use Regenta Eye/Ear Drops in prescribed doses only. Irreversible toxic effects may result from direct contact of the medicine with the middle and inner ear. Seek immediate medical help

Drug Warnings

Inform your doctor if you have any allergic reactions to Gentamicin before starting Regenta Eye/Ear Drops. Avoid touching the dropper with bare hands or taking it closer to the eyelids/ear while administering since it contaminates the dropper tip and solution. If you wear contact lenses, remove them while administering the medicine into the eye. It is advised to check with your doctor before using Regenta Eye/Ear Drops if you are pregnant or breastfeeding. Avoid driving or operating machines since the administration of Regenta Eye/Ear Drops may cause temporary blurred vision for a while. Avoid or limit alcohol consumption during the treatment since Regenta Eye/Ear Drops may cause dizziness. Regenta Eye/Ear Drops should be used for children only when advised by a doctor.

Drug-Drug Interactions

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GentamicinMannitol
Severe

Drug-Drug Interactions

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How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Co-administration of Regenta Eye/Ear Drops 10 ml and Temsirolimus may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Regenta Eye/Ear Drops 10 ml with Temsirolimus can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.
GentamicinMannitol
Severe
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Co-administration of Mannitol with Regenta Eye/Ear Drops 10 ml can increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Regenta Eye/Ear Drops 10 ml and Mannitol, but it can be taken if prescribed by a doctor. If you're having problems like hearing loss, ringing in your ears, feeling dizzy, or having kidney issues, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without a doctor's advice.
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Coadministration of Sirolimus with Regenta Eye/Ear Drops 10 ml may increase the risk or severity of kidney problems.

How to manage the interaction:
Although there is a possible interaction, Regenta Eye/Ear Drops 10 ml can be taken with sirolimus if prescribed by the doctor. Consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting your doctor.
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Taking Regenta Eye/Ear Drops 10 ml with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Although taking Regenta Eye/Ear Drops 10 ml and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
When Rocuronium is used with Regenta Eye/Ear Drops 10 ml, it can make the treatment more effective.

How to manage the interaction:
Co-administration of Rocuronium bromide with Regenta Eye/Ear Drops 10 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
GentamicinMetrizamide
Severe
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Co-administration of Metrizamide with Regenta Eye/Ear Drops 10 ml may increase the risk of kidney problems.

How to manage the interaction:
Taking Regenta Eye/Ear Drops 10 ml with Metrizamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let a doctor know right away. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble with your muscles, balance, or heart rhythm. Do not stop using any medications without a doctor's advice.
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Co-administration of Tenofovir alafenamide may cause kidney problems and combining it Regenta Eye/Ear Drops 10 ml may increase that risk.

How to manage the interaction:
Although there is a possible interaction, Regenta Eye/Ear Drops 10 ml can be taken with tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
GentamicinFoscarnet
Severe
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Co-administration of Regenta Eye/Ear Drops 10 ml with Foscarnet can increase the risk of kidney damage.

How to manage the interaction:
Although taking Regenta Eye/Ear Drops 10 ml and Foscarnet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away: seizures, an irregular heart rhythm, feeling sick, swelling, sudden weight gain or loss, severe pain in your upper stomach, strong heartbeats, feeling dizzy, or chest pain. Do not stop using any medications without a doctor's advice.
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Co-administration of Human immunoglobulin with Regenta Eye/Ear Drops 10 ml may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Regenta Eye/Ear Drops 10 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
GentamicinIopamidol
Severe
How does the drug interact with Regenta Eye/Ear Drops 10 ml:
Co-administration of Iopamidol with Regenta Eye/Ear Drops 10 ml may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Regenta Eye/Ear Drops 10 ml with Iopamidol can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let your doctor know right away. These changes could be a sign of problems with your kidneys, diabetes, or other health issues. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Ear infections:

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Avoid getting things like shampoo, soap, and water into the ear as it can cause itching.
  • Do not poke or scratch the ear as it can cause damage to the ear canal, leading to inflammation. The inflamed skin can be infected by bacteria or fungi, which can cause infections in the ear.

Eye infections:

  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands before inserting and after removing the contact lens.
  • Avoid staring at the digital screens for longer durations. Rest your eyes every 20 minutes.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

Alcohol consumption may worsen the side effects like dizziness; hence please avoid or limit alcohol intake while being treated with Regenta Eye/Ear Drops.

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Pregnancy

Consult your doctor

It is advised to consult your doctor if you plan to conceive or are already pregnant before starting Regenta Eye/Ear Drops.

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Breast Feeding

Consult your doctor

There are limited studies on how Regenta Eye/Ear Drops affects breastfed infants. Please consult your doctor before using Regenta Eye/Ear Drops if you are breastfeeding.

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Driving

Caution

Regenta Eye/Ear Drops may cause side effects like blurry vision or dizziness, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases or hepatic impairment before starting Regenta Eye/Ear Drops.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before starting Regenta Eye/Ear Drops.

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Children

Caution

Regenta Eye/Ear Drops can be used for children above 1 month if prescribed by a doctor.

Have a query?

FAQs

Regenta Eye/Ear Drops is an antibiotic medicine that treats bacterial infections of the eye and ear. It is used to treat infections like conjunctivitis (inflammation of the mucous membrane (conjunctiva) of the eye), keratitis (inflammation of the cornea), keratoconjunctivitis (inflammation of conjunctiva and cornea), blepharitis (inflammation of the eyelids), blepharoconjunctivitis (inflammation of conjunctiva and eyelids), corneal ulcers, and otitis externa (inflammation of the ear).

Regenta Eye/Ear Drops consists of Gentamicin, an antibiotic that prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it treats bacterial infections of the eye and ear.

It is advised to remove your contact lens while administering eye drops. Also, remember to wash your hands before and after administering eye drops to avoid contamination.

If you use other eye ointments/drops along with Regenta Eye/Ear Drops, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any ointments.

Avoid the contact of the dropper or tip with fingers, eyes, and eyelids. Topical eye products, when contaminated by patients with eye diseases, bacterial keratitis (an infection of the cornea) and ocular infections (eye infections) may occur, which result in vision loss.

You must maintain at least a 20-30 minutes gap after instilling Regenta Eye/Ear Drops if you use more than one ear drop formulation.

Country of origin

India
Other Info - REG0177

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