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  3. Reniva-M 500/100 mg Tablet 10's

Reniva-M 500/100 mg Tablet 10's, Pack of 10
Reniva-M 500/100 mg Tablet 10's, Pack of 10
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Reniva-M 500/100 mg Tablet is an anti-diabetic medicine used in the treatment of Type II diabetes. This combination medicine works by increasing the amount of insulin generated by the pancreas and helps remove excess sugar from the body via urine. This medicine may cause common side effects like stomach upset, hypoglycaemia, headache, nausea, and vomiting.
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Composition :

METFORMIN-500MG + REMOGLIFLOZIN-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Reniva-M 500/100 mg Tablet

Reniva-M 500/100 mg Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus adjunct to diet and exercise. Type-2 diabetes mellitus is also known as non-insulin-dependent diabetes or adult-onset diabetes. It is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.
 
Reniva-M 500/100 mg Tablet is a combination of two drugs, namely: Remogliflozin and Metformin. Remogliflozin helps in removing excess sugar from the body via urine. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the body’s sensitivity to insulin. Together, Reniva-M 500/100 mg Tablet helps control the blood sugar levels.
 
Take Reniva-M 500/100 mg Tablet as prescribed. You are advised to take Reniva-M 500/100 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as stomach upset, hypoglycaemia, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Reniva-M 500/100 mg Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Reniva-M 500/100 mg Tablet as it might cause unpleasant side-effects. Limited information is available regarding the usage of Reniva-M 500/100 mg Tablet in children, so please consult a doctor. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Reniva-M 500/100 mg Tablet

Treatment of Type-2 diabetes mellitus

Directions for Use

• Take Reniva-M 500/100 mg Tablet with food to prevent stomach upset or as advised by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow it as a whole with a glass of water.• Do not break, crush or chew it.

Medicinal Benefits

Reniva-M 500/100 mg Tablet contains Remogliflozin and Metformin used to treat type-2 diabetes mellitus. Remogliflozin helps in removing excess sugar from the body via urine. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the body's sensitivity to insulin. Together, Reniva-M 500/100 mg Tablet helps control the blood sugar levels.

How Reniva-M 500/100 mg Tablet Works

Reniva-M 500/100 mg Tablet is a combination of two drugs, namely: Remogliflozin and Metformin. Remogliflozin helps in removing excess sugar from the body via urine. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the body’s sensitivity to insulin. Together, Reniva-M 500/100 mg Tablet helps control the blood sugar levels.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Reniva-M 500/100 mg Tablet out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Reniva-M 500/100 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.

What if I have taken an overdose of Reniva-M 500/100 mg Tablet

Take Reniva-M 500/100 mg Tablet only as prescribed by the physician. Do not exceed the recommended dose as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Reniva-M 500/100 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have heart problems, diabetic ketoacidosis, skin problems, acute pancreatitis, low blood sugar levels, kidney or liver problems. Consult your doctor before taking Reniva-M 500/100 mg Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Reniva-M 500/100 mg Tablet as it might cause unpleasant side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects. 

Drug-Drug Interactions

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MetforminIobitridol
Critical
MetforminIomeprol
Critical

Drug-Drug Interactions

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MetforminIobitridol
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Reniva-M 500/100 mg Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Iomeprol with Reniva-M 500/100 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Iopamidol with Reniva-M 500/100 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoglicic acid
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Ioglicic acid with Reniva-M 500/100 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Iopentol with Reniva-M 500/100 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIofendylate
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Iofendylate with Reniva-M 500/100 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Iotroxic acid with Reniva-M 500/100 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Iopydol with Reniva-M 500/100 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Reniva-M 500/100 mg Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Reniva-M 500/100 mg Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Reniva-M 500/100 mg Tablet:
Co-administration of Iopromide with Reniva-M 500/100 mg Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Reniva-M 500/100 mg Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables in your diet.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Follow a healthy diet and walk for at least 45 minutes to complement treatment with Reniva-M 500/100 mg Tablet .
  • Maintain a healthy weight by exercising regularly.
  • Rest properly, avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Reniva-M 500/100 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Reniva-M 500/100 mg Tablet to prevent unpleasant side effects.

bannner image

Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether Reniva-M 500/100 mg Tablet can be given to breastfeeding mothers or not.

bannner image

Driving

Caution

It is not known if Reniva-M 500/100 mg Tablet affects your ability to drive. Drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Limited information is available regarding the usage of Reniva-M 500/100 mg Tablet in children, so please consult a doctor.

Have a query?

FAQs

Reniva-M 500/100 mg Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus adjunct to diet and exercise.

Reniva-M 500/100 mg Tablet contains Remogliflozin and Metformin. Remogliflozin helps in removing excess sugar from the body via urine. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the body’s sensitivity to insulin. Together, Reniva-M 500/100 mg Tablet helps control the blood sugar levels.

Do not stop taking Reniva-M 500/100 mg Tablet without consulting your doctor as it may cause an increase in blood glucose levels. Continue taking Reniva-M 500/100 mg Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Reniva-M 500/100 mg Tablet .

Hypoglycaemia/low blood sugar levels could be the side effect of Reniva-M 500/100 mg Tablet . Hypoglycaemia generally occurs when Reniva-M 500/100 mg Tablet is taken along with other antidiabetic medicines, without food or with alcohol. Consume sugary food such as candy or fruit juice if you experience hypoglycaemic symptoms such as dizziness, cold sweats, anxiety, or tremor. Regularly monitor blood glucose levels while taking Reniva-M 500/100 mg Tablet .

If you miss a dose, try to take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead. Avoid taking the double dose as it might cause unpleasant side effects or overdose.

Low fibre, high fat diet, sugary diet, obesity, smoking, stress, lack of exercise, age, genetic factors, and certain medical conditions are the common causes of diabetes.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - REN0432

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:24 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.glenmarkpharma.com/sites/default/files/Glenmark-receives-approval-for-combination-of-Remogliflozin-Etabonate-an.pdf
  2. https://www.drugs.com/metformin.html
  3. https://adisinsight.springer.com/drugs/800055671

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