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  3. Riopah 1mg Tablet 10's

Riopah 1mg Tablet 10's, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Riopah 1mg Tablet is used to treat pulmonary arterial hypertension (PAH; high blood pressure in the lungs). It is also used to treat chronic thromboembolic pulmonary hypertension (high blood pressure in the lung arteries). Additionally, it may improve the ability to exercise in people with these conditions and may slow the worsening of symptoms in people with PAH. This medicine works by relaxing the blood vessels in the lungs. This allows blood to flow easily and lowers blood pressure.
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Composition :

RIOCIGUAT-1MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Riopah 1mg Tablet

Riopah 1mg Tablet belongs to the class of medications called soluble guanylate cyclase stimulators. It is also used to treat adults with Pulmonary Arterial Hypertension (PAH), alone or in combination with other medications. Pulmonary hypertension is a type of high blood pressure that affects the arteries in your lungs and the right side of your heart.

Riopah 1mg Tablet contains ‘Riociguat’. It works by relaxing the blood vessels in the lungs. This leads to the relaxation or widening of those vessels. Relaxing and widening the blood vessels in the lungs decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs, which generally results in the ability to be more active.

Riopah 1mg Tablet is taken dose and duration as advised by the doctor. Riopah 1mg Tablet may be prescribed alone or in combination with other blood pressure-lowering medicines depending upon your blood pressure levels. In some cases, Riopah 1mg Tablet can cause side effects like headache, diarrhoea, decreased blood pressure, dizziness, vomiting, nausea, anaemia (low number of red blood cells), gastro-oesophageal reflux disease, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have had an allergic reaction to Riopah 1mg Tablet or any ingredients in it. Let your doctor know if you have any liver disease, kidney disease, heart failure, heart valve problem or history of a heart attack. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor. Keep your doctor informed about your health condition and all the medicines you take before taking Riopah 1mg Tablet to rule out any side effects.

Uses of Riopah 1mg Tablet

Treatment of Pulmonary hypertension

Directions for Use

• Riopah 1mg Tablet can be taken with or without food because food does not significantly affect its absorption or effectiveness.• It is usually taken three times a day, or as prescribed by your doctor.• Swallow Riopah 1mg Tablet as a whole with a glass of water.• Do not chew, crush, or break it.

Medicinal Benefits

Riopah 1mg Tablet  belongs to the class of medications called soluble guanylate cyclase stimulators. Cyclic guanosine monophosphate (cyclic GMP) is a substance produced in the lungs and other parts of the body by an enzyme called guanylate cyclase in response to nitric oxide. Cyclic GMP causes the blood vessels (arteries) to relax and widen. Riociguat increases guanylate cyclase activity in two ways so that more cyclic GMP is available for the blood vessels inside the lungs. This leads to relaxation or widening of those vessels. Relaxing and widening the blood vessels in the lungs decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs, which generally results in the ability to be more active.

How Riopah 1mg Tablet Works

Riopah 1mg Tablet contains ‘Riociguat’. It works by relaxing the blood vessels in the lungs. This leads to the relaxation or widening of those vessels. Relaxing and widening the blood vessels in the lungs decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs, which generally results in the ability to be more active.

Storage

Keep Riopah 1mg Tablet out of sight and reach of children.
Side effects of Riopah 1mg Tablet
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Riopah 1mg Tablet

Take Riopah 1mg Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. In cases of overdose, blood pressure should be closely monitored and supported as needed. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you have had an allergic reaction to Riopah 1mg Tablet or any ingredients in it. Let your doctor know if you have any liver disease, kidney disease, heart failure, heart valve problem or history of a heart attack. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You must closely monitor your blood pressure if you have ever had a stroke, or heart attack or currently taking other blood pressure-lowering pills. Keep your doctor informed about your health condition and all the medicines you take before taking Riopah 1mg Tablet to rule out any side effects. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Do not drive or operate machinery since Riopah 1mg Tablet may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with Riopah 1mg Tablet as it may increase the risk of low blood pressure. Riopah 1mg Tablet is not recommended in patients younger than 18 years of age.

Drug-Drug Interactions

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RiociguatSildenafil
Critical
RiociguatTheophylline
Critical

Drug-Drug Interactions

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RiociguatSildenafil
Critical
How does the drug interact with Riopah 1mg Tablet:
Co-administration of Sildenafil with Riopah 1mg Tablet may lower the blood pressure.

How to manage the interaction:
Taking Riopah 1mg Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RiociguatTheophylline
Critical
How does the drug interact with Riopah 1mg Tablet:
Co-administration of Theophylline with Riopah 1mg Tablet can increase the risk of low blood pressure.

How to manage the interaction:
Taking Theophylline with Riopah 1mg Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
RiociguatIsosorbide mononitrate
Critical
How does the drug interact with Riopah 1mg Tablet:
Taking Riopah 1mg Tablet with Isosorbide mononitrate can cause low blood pressure.

How to manage the interaction:
Taking Isosorbide mononitrate with Riopah 1mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
RiociguatNitroprusside
Critical
How does the drug interact with Riopah 1mg Tablet:
Coadministration of Nitroprusside with Riopah 1mg Tablet can increase the risk of low blood pressure.

How to manage the interaction:
Taking Nitroprusside with Riopah 1mg Tablet is avoided, but it can be taken when prescribed by your doctor. However, contact your doctor immediately if you experience any side effects such as dizziness, lightheadedness, headache, and nasal congestion. Do not discontinue any medications without consulting a doctor.
RiociguatDipyridamole
Critical
How does the drug interact with Riopah 1mg Tablet:
Taking Dipyridamole with Riopah 1mg Tablet may lower blood pressure.

How to manage the interaction:
Taking Dipyridamole with Riopah 1mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion Do not discontinue any medications without consulting a doctor.
RiociguatIsosorbide dinitrate
Critical
How does the drug interact with Riopah 1mg Tablet:
Taking Riopah 1mg Tablet with Isosorbide dinitrate may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate with Riopah 1mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
RiociguatAminophylline
Critical
How does the drug interact with Riopah 1mg Tablet:
Coadministration of Aminophylline with Riopah 1mg Tablet may significantly lower your blood pressure.

How to manage the interaction:
Taking Aminophylline with Riopah 1mg Tablet can cause an interaction, however, it can be taken only if a doctor has advised it. If you experience dizziness, lightheadedness, shortness of breath, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RiociguatAvanafil
Critical
How does the drug interact with Riopah 1mg Tablet:
Taking Avanafil with Riopah 1mg Tablet may significantly lower blood pressure.

How to manage the interaction:
Taking Riopah 1mg Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion Do not discontinue any medications without consulting a doctor.
RiociguatTadalafil
Critical
How does the drug interact with Riopah 1mg Tablet:
Taking Tadalafil with Riopah 1mg Tablet may increase the risk or severity of lower the blood pressure.

How to manage the interaction:
Taking Riopah 1mg Tablet with Tadalafil is generally not recommended as it can lead to an interaction, but it can be taken together if prescribed by a doctor. However, if you experience dizziness, headache, and nasal congestion consult a doctor. Do not discontinue any medications without consulting a doctor.
RiociguatVardenafil
Critical
How does the drug interact with Riopah 1mg Tablet:
Taking Vardenafil with Riopah 1mg Tablet may significantly lower the blood pressure.

How to manage the interaction:
Taking Riopah 1mg Tablet with Vardenafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Reduce sodium intake in your diet to maintain your blood pressure.
  • Eat natural and healthy foods by cutting down on high-sodium processed foods.
  • Lose those extra pounds since being obese can be a risk factor for hypertension.
  • Exercise regularly to maintain good heart health.
  • Avoid smoking and alcohol intake.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time to relax and do activities you enjoy.
  • Try to include heart-healthy omega-3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Riopah 1mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advised to limit alcohol intake since alcohol consumption with Riopah 1mg Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Riopah 1mg Tablet in pregnant women.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Riopah 1mg Tablet in breastfeeding/nursing mothers.

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Driving

Caution

It is not known whether Riopah 1mg Tablet alters the ability to drive. Do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

bannner image

Liver

Caution

Please consult your doctor if you have any concerns regarding using Riopah 1mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using Riopah 1mg Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the use of Riopah 1mg Tablet in children. Please consult your doctor.

Have a query?

FAQs

Riopah 1mg Tablet is used to treat pulmonary arterial hypertension (high blood pressure in the lungs).

Riopah 1mg Tablet contains ‘Riociguat’. It works by relaxing the blood vessels in the lungs to allow blood to flow easily. Thereby, it increases the blood supply to the lungs.

Please do not stop using Riopah 1mg Tablet without consulting your doctor on your own. Continue using Riopah 1mg Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Riopah 1mg Tablet .

Riopah 1mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Riopah 1mg Tablet belongs to the group of medications called soluble guanylate cyclase stimulators used to treat Pulmonary Arterial Hypertension (PAH). It works by relaxing and widening blood vessels in the lungs, reducing pulmonary pressure and improving heart function. This helps lower blood pressure in the lungs and enhances physical activity.

Patients with lactose intolerance should exercise caution when taking Riopah 1mg Tablet . If you have a rare hereditary problem such as galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption, you should not take Riopah 1mg Tablet due to its lactose content. Consult your healthcare professional for guidance and concerns.

It's not recommended to take Riopah 1mg Tablet and sildenafil together, as this combination may increase the risk of significant hypotension (low blood pressure). Using these medications together can lead to side effects such as dizziness, light-headedness, flushing, fainting, headache, and nasal congestion. To ensure safe use, do not take them together; instead, consult your doctor or seek medical attention for guidance.

To make swallowing Riopah 1mg Tablet easier, take it with a full glass of water or use a pill-swallowing aid. Please consult your doctor about alternative options, like crushing or splitting the tablet if needed.

Regular blood pressure monitoring is crucial while taking Riopah 1mg Tablet to ensure its effectiveness and safety. This is because Riopah 1mg Tablet can cause low blood pressure (hypotension), dizziness, fainting, or weakness. By regularly monitoring blood pressure, you can detect any sudden drops or fluctuations, allowing for timely adjustments to the dosage if needed and ensuring safe and effective treatment under your doctor's guidance.

The side effects of Riopah 1mg Tablet include headache, dizziness, diarrhoea, decreased blood pressure, vomiting, nausea, anemia (low number of red blood cells), gastro-oesophageal reflux disease, and constipation. These side effects are not familiar to everyone and vary individually. Please consult the doctor if you notice any side effects that are not manageable.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RIO0046

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:54 AM IST

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Reference

  1. https://phassociation.org/patients/treatments/riociguat/
  2. https://reference.medscape.com/drug/adempas-riociguat-999863

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