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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sainzen-K (AS) Capsule is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. It contains Diclofenac and Serratiopeptidase, which works by inhibiting the production od substnaces that cause pain and swelling at the injured or damaged tissue.Also, it helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue. It may cause common side effects like stomach pain, diarrhoea, nausea, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Sain Medicaments Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sainzen-K (AS) Capsule

Sainzen-K (AS) Capsule belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of diclofenac and serratiopeptidase. Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury.

Sainzen-K (AS) Capsule is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

You can take Sainzen-K (AS) Capsule with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take Sainzen-K (AS) Capsule based on your medical condition. Sainzen-K (AS) Capsule may have common side effects like stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Sainzen-K (AS) Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Sainzen-K (AS) Capsule if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. Sainzen-K (AS) Capsule may be associated with a small increased risk of heart attack ‘myocardial infarction. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Sainzen-K (AS) Capsule

Sainzen-K (AS) Capsule is used in the treatment of pain. The detailed uses of Sainzen-K (AS) Capsule are as follows:

  • Relieve pain: Sainzen-K (AS) Capsule is used to treat pain in conditions such as osteoarthritis and rheumatoid arthritis, spondylitis and ankylosing spondylitis, dental pain, migraine and tension headaches, soft tissue injuries and menstrual pain (dysmenorrhea).
  • Post-traumatic pain: Sainzen-K (AS) Capsule is used in the post-traumatic pain (e.g. sprains, strains, fractures).

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Directions for Use

  • Sainzen-K (AS) Capsule can be taken with or without food. However, taking it with food may help reduce stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Sainzen-K (AS) Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Sainzen-K (AS) Capsule plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Sainzen-K (AS) Capsule relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Serratiopeptidase present in Sainzen-K (AS) Capsule is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

How Sainzen-K (AS) Capsule Works

Sainzen-K (AS) Capsule is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Sainzen-K (AS) Capsule

Do not take more than the prescribed dose of Sainzen-K (AS) Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Sainzen-K (AS) Capsule as it may lead to an increase in the risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Sainzen-K (AS) Capsule. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to pain killers and, complications like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Sainzen-K (AS) Capsule. Do not drive or operate heavy machinery as intake of Sainzen-K (AS) Capsule may cause dizziness. Patients who had recently undergone heart bypass surgery should take Sainzen-K (AS) Capsule with caution and only under medical supervision. Use of Sainzen-K (AS) Capsule is contraindicated in kidney failure patients or who are undergoing dialysis.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Sainzen-K (AS) Capsule:
Co-administration of Sainzen-K (AS) Capsule with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Sainzen-K (AS) Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Sainzen-K (AS) Capsule:
Concomitant administration of Sainzen-K (AS) Capsule and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Sainzen-K (AS) Capsule and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Sainzen-K (AS) Capsule:
Coadministration of Sainzen-K (AS) Capsule and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Sainzen-K (AS) Capsule and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Sainzen-K (AS) Capsule:
The combined use of Sainzen-K (AS) Capsule and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Sainzen-K (AS) Capsule and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Sainzen-K (AS) Capsule:
Co-administration of Sainzen-K (AS) Capsule with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Sainzen-K (AS) Capsule and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Sainzen-K (AS) Capsule:
Co-administration of Sainzen-K (AS) Capsule and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Sainzen-K (AS) Capsule and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DiclofenacOmacetaxine mepesuccinate
Severe
How does the drug interact with Sainzen-K (AS) Capsule:
Taking Sainzen-K (AS) Capsule with Omacetaxine mepesuccinate can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Sainzen-K (AS) Capsule and Omacetaxine mepesuccinate but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacLomitapide
Severe
How does the drug interact with Sainzen-K (AS) Capsule:
Taking Sainzen-K (AS) Capsule with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between Sainzen-K (AS) Capsule and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
DiclofenacSulindac
Severe
How does the drug interact with Sainzen-K (AS) Capsule:
Co-administration of Sainzen-K (AS) Capsule and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Sainzen-K (AS) Capsule and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Sainzen-K (AS) Capsule:
Coadministration of Sainzen-K (AS) Capsule with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Sainzen-K (AS) Capsule and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a foot rest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Alcohol

Caution

You are recommended not to consume alcohol along with Sainzen-K (AS) Capsule to avoid unpleasant side-effects.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant before taking Sainzen-K (AS) Capsule.

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Breast Feeding

Caution

Sainzen-K (AS) Capsule may pass into the breast milk. Consult your doctor for more information on this if you are a breastfeeding mother.

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Driving

Caution

Sainzen-K (AS) Capsule may affect driving as it causes dizziness. Drive or operate machinery only when you are alert.

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Liver

Caution

Sainzen-K (AS) Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Sainzen-K (AS) Capsule to be taken with caution if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Sainzen-K (AS) Capsule is not recommended for children under 10 years of age. For them dose has to be adjusted and recommended by a child specialist only.

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Heart

Sainzen-K (AS) Capsule should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Caution

Sainzen-K (AS) Capsule should be used under caution in geriatric patients as it can lead to serious side effects/

FAQs

Sainzen-K (AS) Capsule is used in the treatment of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain.

Sainzen-K (AS) Capsule when taken by patients who are allergic to pain-killers can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.

You should only take Sainzen-K (AS) Capsule if doctor has prescribed you. The maximum recommended dose of Sainzen-K (AS) Capsule is twice daily. Sainzen-K (AS) Capsule can be one in the morning and one in the evening.

Rheutamoid arthritis is an autoimmune disease that causes chronic inflammation and pain of the joints.

Ankylosing spondylitis is a arthritis of the spine which can lead to the fusion of the vertebrae, lead to pain and inflammation in the spine.

Country of origin

India
Other Info - SA61568

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