Simbrinza Opthalmic Suspension 5 ml
MRP ₹731.5
(Inclusive of all Taxes)
₹109.7 Cashback (15%)
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About Simbrinza Opthalmic Suspension 5 ml
Simbrinza Opthalmic Suspension 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Glaucoma causes damage to the optic nerve and results in reduced vision. Ocular hypertension is increased pressure in the eye.
Simbrinza Opthalmic Suspension 5 ml contains Brinzolamide and Brimonidine, which decrease the production of aqueous humour, thereby helping lower the increased pressure in the eye.
This medicine may cause side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Talk to your doctor if you experience these side effects persistently.
Consult a doctor if you are pregnant or breastfeeding. Simbrinza Opthalmic Suspension 5 ml might cause dizziness, drowsiness, and abnormal/blurred vision, so drive only if you have clear vision.
Uses of Simbrinza Opthalmic Suspension 5 ml
Simbrinza Opthalmic Suspension 5 ml is used to manage elevated eye pressure. The detailed uses of Simbrinza Opthalmic Suspension 5 ml include:
- Treatment of open-angle glaucoma: Simbrinza Opthalmic Suspension 5 ml helps reduce intraocular pressure in individuals with open-angle glaucoma, thereby preventing damage to the optic nerve and vision loss.
- Management of ocular hypertension: Simbrinza Opthalmic Suspension 5 ml lowers high pressure inside the eyes in patients without glaucoma but who are at risk, helping to reduce the likelihood of future optic nerve damage.
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Directions for Use
- Simbrinza Opthalmic Suspension 5 ml is for ophthalmic (for eye) use only.
- It is recommended to apply one drop of Simbrinza Opthalmic Suspension 5 ml thrice daily or as prescribed by your doctor.
- Check the label for directions before using this medication.
- Lie down and tilt your head backwards. Gently pull your lower eyelid with your index finger to form a pocket. Instil the prescribed number of drops into the pocket. Close your eyes for 1-2 minutes.
- Replace the cap tightly after each use.
- Avoid touching the container tip to the eye or eyelids to prevent contamination.
Medicinal Benefits
- Simbrinza Opthalmic Suspension 5 ml helps decrease high pressure inside the eyes, a major risk factor for optic nerve damage and vision loss in glaucoma.
- Brinzolamide (a carbonic anhydrase inhibitor) works by reducing the formation of aqueous humour (fluid in the eye).
- Brimonidine (an alpha-2 adrenergic receptor agonist) lowers IOP by decreasing fluid production and increasing fluid drainage.
- By maintaining normal eye pressure, Simbrinza Opthalmic Suspension 5 ml helps protect the optic nerve and supports long-term vision health.
- It is suitable for patients who require combination therapy to achieve target intraocular pressure levels.
- It combines two active ingredients in a single formulation, improving patient compliance and treatment outcomes.
How Simbrinza Opthalmic Suspension 5 ml Works
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What if I have taken an overdose of Simbrinza Opthalmic Suspension 5 ml
Drug Warnings
- Do not use Simbrinza Opthalmic Suspension 5 ml if you are allergic to any of its components, if you are taking monoamine oxidase inhibitors, antidepressants, if you have severe kidney problems or excess acidity in the blood.
- Inform your doctor if you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, or poor or disturbed blood circulation.
- Consult your doctor before using Simbrinza Opthalmic Suspension 5 ml if you are pregnant or breastfeeding.
- Simbrinza Opthalmic Suspension 5 ml is not recommended for children below 18 years, as safety and effectiveness have not been established.
- Simbrinza Opthalmic Suspension 5 ml might cause dizziness, drowsiness, abnormal/blurred vision; so, drive only if you are alert.
- Let your doctor know if you are taking any other medicines, including supplements or herbal products.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Simbrinza Opthalmic Suspension 5 ml with Aspirin may cause side effects.
How to manage the interaction:
Although there is a possible interaction between aspirin and Simbrinza Opthalmic Suspension 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, please contact a doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Simbrinza Opthalmic Suspension 5 ml with diflunisal can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction, Simbrinza Opthalmic Suspension 5 ml should be used with diflunisal only if prescribed by the doctor. Consult a doctor if you experience vomiting, headache, dizziness, or fever. Do not stop using any medications without first talking to your doctor.
Concomitant use of Simbrinza Opthalmic Suspension 5 ml with sodium salicylate may cause ringing in the ears, nausea, vomiting, headache, dizziness, confusion, hallucinations, rapid breathing, fever, and seizure (convulsions).
How to manage the interaction:
Although there is an interaction, Simbrinza Opthalmic Suspension 5 ml should be used with sodium salicylate only if prescribed by the doctor. However, if you experience ringing in the ears, vomiting, headache, dizziness, or fever, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
Concomitant use of Simbrinza Opthalmic Suspension 5 ml with salsalate can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction, Simbrinza Opthalmic Suspension 5 ml should be used with salsalate only if prescribed by the doctor. Consult a doctor immediately if you experience ringing in the ears, vomiting, headache, dizziness, and fever. Do not stop using any medications without first talking to your doctor.
Taking Simbrinza Opthalmic Suspension 5 ml with Choline salicylate may increase the risk of side effects.
How to manage the interaction:
Although taking Simbrinza Opthalmic Suspension 5 ml and Choline salicylate together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
Simbrinza Opthalmic Suspension 5 ml may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Concomitant use of brivaracetam with Simbrinza Opthalmic Suspension 5 ml may increase the risk of these side effects.
How to manage the interaction:
Although there is an interaction brivaracetam can be taken with Simbrinza Opthalmic Suspension 5 ml if prescribed by the doctor. Consult the prescriber if you notice dizziness, drowsiness, and difficulty concentrating.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Include fresh fruits and vegetables in your diet.
- Avoid smoking and alcohol consumption.
- Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine, as these foods may worsen glaucoma and damage the optic nerve.
- Cut down your coffee intake as it may increase pressure in the eye. Replace coffee with green tea.
- Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.
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Alcohol
Caution
Avoid consuming alcohol while using Simbrinza Opthalmic Suspension 5 ml as it might cause increased dizziness and drowsiness. Please consult your doctor if you have any concerns.
Pregnancy
Unsafe
Simbrinza Opthalmic Suspension 5 ml belongs to pregnancy category C. Use effective contraception while using Simbrinza Opthalmic Suspension 5 ml. Avoid using Simbrinza Opthalmic Suspension 5 ml during pregnancy unless clearly indicated by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Unsafe
Simbrinza Opthalmic Suspension 5 ml might pass into breastmilk. Avoid breastfeeding while using Simbrinza Opthalmic Suspension 5 ml.
Driving
Unsafe
Simbrinza Opthalmic Suspension 5 ml might cause dizziness, drowsiness, and blurred/abnormal vision. So, avoid driving or operating machinery until your vision is clear.
Liver
Caution
Please consult your doctor if you have any concerns regarding the usage of Simbrinza Opthalmic Suspension 5 ml in patients with liver impairment.
Kidney
Caution
Please consult your doctor if you have any concerns regarding the usage of Simbrinza Opthalmic Suspension 5 ml in patients with kidney impairment. Simbrinza Opthalmic Suspension 5 ml is not recommended for patients with severe kidney disease.
Children
Unsafe
Simbrinza Opthalmic Suspension 5 ml is not recommended for children below 18 years, as the safety and effectiveness have not been established.
Heart
Please inform your doctor if you have a history of heart disease before using Simbrinza Opthalmic Suspension 5 ml. Your doctor will prescribe it only if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Simbrinza Opthalmic Suspension 5 ml should be used in elderly patients only if prescribed by a doctor. If you have any concerns about using Simbrinza Opthalmic Suspension 5 ml in older adults, please consult your doctor.
FAQs
Simbrinza Opthalmic Suspension 5 ml is used to lower high intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Simbrinza Opthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helping to lower the increased pressure in the eye.
Continue using Simbrinza Opthalmic Suspension 5 ml for as long as your doctor has prescribed it to you. Consult the doctor if irritation occurs or worsens.
Simbrinza Opthalmic Suspension 5 ml might cause blurred or abnormal vision. So, avoid driving or operating machinery until your vision is clear to prevent any mishap.
Do not wear contact lenses while using Simbrinza Opthalmic Suspension 5 ml. Remove contact lenses before using Simbrinza Opthalmic Suspension 5 ml and put them back 15minutes after using Simbrinza Opthalmic Suspension 5 ml.
Dry mouth could be a side effect of Simbrinza Opthalmic Suspension 5 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Simbrinza Opthalmic Suspension 5 ml can be used with other eye medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Simbrinza Opthalmic Suspension 5 ml and other eye medications.
Simbrinza Opthalmic Suspension 5 ml may cause common side effects such as blurred vision, eye redness, discomfort, drowsiness, and a bad taste in the mouth. In most cases, these side effects are temporary and don't require medical attention, resolving on their own over time. However, if you experience persistent side effects, it's best to consult your doctor for guidance.
Yes, Simbrinza Opthalmic Suspension 5 ml requires a prescription. It is a combination of brinzolamide and brimonidine, used to treat elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Simbrinza Opthalmic Suspension 5 ml is not recommended for individuals allergic to its components, those taking monoamine oxidase inhibitors or antidepressants, and people with severe kidney problems or excess acidity in the blood. Additionally, children under 18 years old should not take Simbrinza Opthalmic Suspension 5 ml, as its safety and effectiveness have not been established. If you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, or poor blood circulation, inform your doctor before taking pramipexole.
Lie down and tilt your head backwards. Gently pull your lower eyelid with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
Simbrinza Opthalmic Suspension 5 ml is not recommended for use during pregnancy and breastfeeding unless prescribed by the doctor. The risks and benefits should be carefully discussed with your doctor before using this medication.
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