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Simlo EZ 10 mg Tablet belongs to the class of medicines called 'anti hyperlipidemic drugs' or cholesterol-lowering agents primarily used to lower bad cholesterol and triglycerides (type of fat) and increase good cholesterol levels. This reduces the risk of heart attack and stroke in future. High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy cholesterol balance in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged, contributing to heart diseases like stroke and heart attack.
Simlo EZ 10 mg Tablet is a combination of Ezetimibe and Simvastatin. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract. Simvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart.
Take Simlo EZ 10 mg Tablet as prescribed. Your doctor will advise how often you take Simlo EZ 10 mg Tablet based on your medical condition. Sometimes, this medicine may cause common side effects such as muscle pain, headache, diarrhoea, upper respiratory tract infection or increased liver enzyme levels. Most of these side effects of Simlo EZ 10 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Ezetimibe, Simvastatin or other medicines, please tell your doctor. If you are aged 65 years or older, please inform your doctor. Avoid using Simlo EZ 10 mg Tablet if you are pregnant. Also, you are advised to take effective birth control measures while taking Simlo EZ 10 mg Tablet to avoid pregnancy. Please inform your doctor if you are a breastfeeding mother. Simlo EZ 10 mg Tablet is not recommended for children below 10 years of age as the safety and effectiveness were not established. If you feel dizzy after taking Simlo EZ 10 mg Tablet , avoid driving or operating machinery.
Simlo EZ 10 mg Tablet is used in the treatment of High cholesterol and prevention of heart attack and stroke. The detailed uses of Simlo EZ 10 mg Tablet are as follows:
Simlo EZ 10 mg Tablet contains Ezetimibe and Simvastatin, used to lower the levels of bad cholesterol and triglycerides (type of fat) and increase good cholesterol levels. This reduces the risk of heart attack and stroke in future. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract. Simvastatin works by inhibiting the production of cholesterol your body makes by itself. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Simlo EZ 10 mg Tablet is used for patients whose cholesterol levels are not controlled by diet and exercise alone.
Unsafe
Avoid consumption of alcohol with Simlo EZ 10 mg Tablet as it may increase the risk of liver damage. Inform your doctor if you consume alcohol daily.
Unsafe
Simlo EZ 10 mg Tablet is not recommended in pregnancy as it may harm your unborn baby. If pregnancy occurs while on treatment with Simlo EZ 10 mg Tablet , it should be discontinued immediately and seek medical advice.
Consult your doctor
It is unknown whether Simlo EZ 10 mg Tablet is excreted in the breast milk. Therefore, if you are a breastfeeding mother, inform your doctor before taking Simlo EZ 10 mg Tablet .
Caution
Simlo EZ 10 mg Tablet usually does not affect your ability to drive or operate machinery. However, if you feel dizzy after taking Simlo EZ 10 mg Tablet , avoid driving or operating machinery.
Caution
Simlo EZ 10 mg Tablet is contraindicated in patients with active liver disease or unexplained persistent elevations in liver transaminases. If you have liver problems, inform your doctor before taking this medicine.
Consult your doctor
If you have chronic kidney disease, inform your doctor before taking Simlo EZ 10 mg Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
Caution
Simlo EZ 10 mg Tablet is not recommended for children below 10 years of age as the safety and effectiveness were not established.
Safe if prescribed
Simlo EZ 10 mg Tablet is generally safe for heart patients if prescribed, but should be used under medical supervision.
Safe if prescribed
Simlo EZ 10 mg Tablet is generally safe for elderly patients. However, please consult your doctor if you have any concerns.

Have a query?
If you are allergic to Ezetimibe, Simvastatin or any other medicines, please tell your doctor. If you are aged 65 years or older, please inform your doctor. Avoid using Simlo EZ 10 mg Tablet if you are pregnant. Also, you are advised to take effective birth control measures while taking Simlo EZ 10 mg Tablet to avoid pregnancy. Please inform your doctor if you are a breastfeeding mother. Simlo EZ 10 mg Tablet is not recommended for children below 10 years of age as the safety and effectiveness were not established. If you feel dizzy after taking Simlo EZ 10 mg Tablet , avoid driving or operating machinery. Maintain a low-fat diet along with Simlo EZ 10 mg Tablet for effective results. If you have diabetes or are at risk of developing diabetes, your doctor will monitor you closely while on treatment with Simlo EZ 10 mg Tablet . You are likely to be at risk of developing diabetes if you have high levels of sugars and fats in the blood, high blood pressure and are overweight.
Drug-Drug Interaction: Avoid taking Simlo EZ 10 mg Tablet if you take antifungals (posaconazole, ketoconazole, itraconazole, voriconazole), antibiotics (clarithromycin, erythromycin, telithromycin), medicines used to treat HIV/AIDS (indinavir, saquinavir, nelfinavir, tipranavir, ritonavir, atazanavir), antidepressants (nefazodone), medicines containing cobicistat, a medicine used to manage endometriosis (danazol), immunosuppressant (cyclosporine), or drugs used to treat hepatitis C (telaprevir, boceprevir). Inform your doctor if you are taking other medicines used to lower cholesterol (fenofibrate, lomitapide, gemfibrozil), antiarrhythmic drugs (amiodarone, dronedarone), medicines used to treat high blood pressure, chest pain associated with heart disease (diltiazem, verapamil, ranolazine, amlodipine), anti-gout drug (colchicine), vitamin B3 (niacin), or blood thinners (warfarin).
Drug-Food Interaction: Avoid consumption of grapefruit juice with Simlo EZ 10 mg Tablet as it may increase the risk of muscle problems.
Drug-Disease Interaction: If you have unexplained muscle pains or weakness, severe lung disease, diabetes, thyroid, kidney or liver problems, inform your doctor before taking Simlo EZ 10 mg Tablet .
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Simlo EZ 10 mg Tablet is used to treat high cholesterol and Prevent heart attacks and strokes.
Simlo EZ 10 mg Tablet contains Ezetimibe and Simvastatin. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract. Simvastatin works by inhibiting the production of cholesterol your body makes by itself. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart.
You are recommended to inform your doctor if you are taking niacin or niacin-containing product, as it may increase the risk of muscle problems.
Simlo EZ 10 mg Tablet may increase the risk of rhabdomyolysis (the breakdown of muscle tissue) in some patients. It is not common for everyone who takes Simlo EZ 10 mg Tablet . However, if you experience unexplained muscle pain, weakness or tenderness, especially along with fever, dark-coloured urine or unusual tiredness, please consult your doctor immediately.
You are not recommended to stop taking Simlo EZ 10 mg Tablet without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Simlo EZ 10 mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Simlo EZ 10 mg Tablet , please consult your doctor so that the dose may be gradually reduced.
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