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  3. Simtil 10 mg Tablet 10's

Simtil 10 mg Tablet 10's, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Simtil 10 mg Tablet 10's is used to treat high cholesterol. It contains Simvastatin which works by lowering the levels of bad cholesterol, and triglycerides and raising the levels of good cholesterol. In some cases, this medicine may cause side effects such as headache, stomach pain, constipation, and nausea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

SIMVASTATIN-10MG

Manufacturer/Marketer :

Tablets India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Simtil 10 mg Tablet 10's

Simtil 10 mg Tablet 10's is used to lower the levels of increased cholesterol in the body. Additionally, Simtil 10 mg Tablet 10's is also used to lower the risk of heart diseases such as heart attack or stroke. High cholesterol levels might cause a build-up of cholesterol on the artery walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke.

Simtil 10 mg Tablet 10's contains 'Simvastatin' that works by blocking HMG-CoA reductase, an enzyme necessary for cholesterol production in the body. Simtil 10 mg Tablet 10's helps lower the levels of LDL (bad) cholesterol, and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Simtil 10 mg Tablet 10's lowers the raised levels of fats, triglycerides and cholesterol, which lowers the risk of heart attack or stroke. 

You are advised to take Simtil 10 mg Tablet 10's as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side effects, such as headache, stomach pain, constipation, and nausea in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Simtil 10 mg Tablet 10's if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Simtil 10 mg Tablet 10's and consult a doctor immediately if you become pregnant while taking Simtil 10 mg Tablet 10's. Simtil 10 mg Tablet 10's may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Simtil 10 mg Tablet 10's as it could lead to increased dizziness. Simtil 10 mg Tablet 10's is not recommended for children below 10 years as safety and effectiveness have not been established. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side effects or interactions.

Uses of Simtil 10 mg Tablet 10's

Treatment of Hyperlipidaemia (high cholesterol)

Directions for Use

Swallow Simtil 10 mg Tablet 10's a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Simtil 10 mg Tablet 10's contains 'Simvastatin', which belongs to a group of lipid-lowering agents called HMG-CoA reductase inhibitors to lower the increased levels of cholesterol or fat. Simtil 10 mg Tablet 10's works by blocking the HMG-CoA reductase enzyme, which is necessary for cholesterol production in the body. Simtil 10 mg Tablet 10's helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Simtil 10 mg Tablet 10's lowers the blood level of fats and cholesterol and helps prevent a heart attack or stroke. Simtil 10 mg Tablet 10's as an adjunct to dietary measures is used to reduce the risk of having a heart event due to cardiovascular diseases, the incidence of non-fatal heart attack or stroke, the need for revascularisation procedures (restoration of blood flow to the heart), people with diabetes, pre-existing heart disease, and peripheral vascular disease.  

How Simtil 10 mg Tablet 10's Works

Simtil 10 mg Tablet 10's contains 'Simvastatin' that works by blocking HMG-CoA reductase, an enzyme necessary for cholesterol production in the body. Simtil 10 mg Tablet 10's helps lower the levels of LDL (bad) cholesterol, and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Simtil 10 mg Tablet 10's lowers the raised levels of fats, triglycerides and cholesterol, which lowers the risk of heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight
Side effects of Simtil 10 mg Tablet
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.

What if I have taken an overdose of Simtil 10 mg Tablet 10's

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Simtil 10 mg Tablet 10's if you are allergic to any of its contents; if you are taking fusidic acid or have taken it in the past 7 days. Inform your doctor if you are due to have surgery, drink large amounts of alcohol; if you have liver or kidney problems. Do not take Simtil 10 mg Tablet 10's if you are pregnant, breastfeeding, think you may be pregnant or if you are trying for pregnancy. Stop taking Simtil 10 mg Tablet 10's and consult a doctor immediately if you become pregnant while taking Simtil 10 mg Tablet 10's. Simtil 10 mg Tablet 10's may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Simtil 10 mg Tablet 10's as it could lead to increased dizziness. Simtil 10 mg Tablet 10's is not recommended for children below 10 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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SimvastatinIdelalisib
Critical
SimvastatinTelithromycin
Critical

Drug-Drug Interactions

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SimvastatinIdelalisib
Critical
How does the drug interact with Simtil 10 mg Tablet:
Combining Idelalisib and Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Idelalisib and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinTelithromycin
Critical
How does the drug interact with Simtil 10 mg Tablet:
Combining Telithromycin and Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Telithromycin and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinFosamprenavir
Critical
How does the drug interact with Simtil 10 mg Tablet:
Combining Fosamprenavir and Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Fosamprenavir and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinErythromycin
Critical
How does the drug interact with Simtil 10 mg Tablet:
Coadministration of erythromycin and Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Erythromycin and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain or weakness, dark-colored urine, joint pain, itching, fatigue, or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinPosaconazole
Critical
How does the drug interact with Simtil 10 mg Tablet:
Taking Posaconazole with Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Posaconazole and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinNefazodone
Critical
How does the drug interact with Simtil 10 mg Tablet:
Combining Nefazodone and Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Nefazodone and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinVoriconazole
Critical
How does the drug interact with Simtil 10 mg Tablet:
Taking Voriconazole and Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects (liver damage and rhabdomyolysis - involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Voriconazole and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience muscle pain, fever or dark-colored urine, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinMifepristone
Critical
How does the drug interact with Simtil 10 mg Tablet:
Combining Mifepristone with Simtil 10 mg Tablet can increase the blood levels of Simtil 10 mg Tablet, which may increase the risk of side effects.

How to manage the interaction:
Taking Simtil 10 mg Tablet with Mifepristone is not recommended, but can be taken if prescribed by the doctor. If you experience any symptoms, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinSaquinavir
Critical
How does the drug interact with Simtil 10 mg Tablet:
Combining Saquinavir and Simtil 10 mg Tablet can increase the blood levels and effects of Simtil 10 mg Tablet. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Saquinavir and Simtil 10 mg Tablet together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-coloured urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinRitonavir
Critical
How does the drug interact with Simtil 10 mg Tablet:
Taking Ritonavir and Simtil 10 mg Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Simtil 10 mg Tablet with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, tiredness, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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SIMVASTATIN-10MGGrapefruit and Grapefruit Juice, Vitamin-K rich foods
Severe

Drug-Food Interactions

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SIMVASTATIN-10MGGrapefruit and Grapefruit Juice, Vitamin-K rich foods
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, Green Tea

How to manage the interaction:
Taking grapefruit or grape juice and green tea or green tea extracts can increase the blood levels of Simtil 10 mg Tablet and can increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). Taking grapefruit or grape juice and green tea or green tea extracts can lead to an interaction. However, if you experience any symptoms like muscle pain, tenderness, or weakness during treatment, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Avoid taking grapefruit or grape juice and green tea or green tea extracts.

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.

  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.

  • Limit salt and sugar intake.

  • Avoid smoking and alcohol consumption. 

  • Choose healthy fats and cut down on trans-fat.

  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.

  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Simtil 10 mg Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Simtil 10 mg Tablet 10's as it may cause increased dizziness.

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Pregnancy

Unsafe

Simtil 10 mg Tablet 10's belongs to pregnancy category X. Do not take Simtil 10 mg Tablet 10's if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Simtil 10 mg Tablet 10's and consult a doctor immediately if you become pregnant while taking Simtil 10 mg Tablet 10's.

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Breast Feeding

Unsafe

It is not known if Simtil 10 mg Tablet 10's passes into breastmilk. Do not take Simtil 10 mg Tablet 10's if you are breastfeeding.

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Driving

Caution

Usually, Simtil 10 mg Tablet 10's does not interfere with your ability to drive or usage of machinery. However, Simtil 10 mg Tablet 10's may cause dizziness in some people. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Simtil 10 mg Tablet 10's is not recommended for children below 10years as the safety and effectiveness have not been established.

Have a query?

FAQs

Simtil 10 mg Tablet 10's is used to lower the levels of increased cholesterol in the body. Additionally, Simtil 10 mg Tablet 10's is also used to lower the risk of heart diseases such as heart attack or stroke.

Simtil 10 mg Tablet 10's works by blocking HMG-CoA reductase, an enzyme necessary for the production of cholesterol in the body. Simtil 10 mg Tablet 10's helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Simtil 10 mg Tablet 10's lowers the blood level of raised fats and cholesterol and helps prevent a heart attack or stroke.

Do not discontinue Simtil 10 mg Tablet 10's without consulting your doctor as it could lead to the rise of cholesterol. To treat your condition effectually, continue taking Simtil 10 mg Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Simtil 10 mg Tablet 10's.

Constipation could be a side-effect of Simtil 10 mg Tablet 10's. Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you have severe constipation.

Simtil 10 mg Tablet 10's can be taken by diabetes patients if prescribed by the doctor. Your doctor will monitor your condition closely if you have diabetes. Regular monitoring of blood sugar levels is advised.

Simtil 10 mg Tablet 10's should not be taken with antibiotics such as fusidic acid as it could lead to a serious muscle problem called rhabdomyolysis (the breakdown of muscle tissue). Inform the doctor that you are taking Simtil 10 mg Tablet 10's if your doctor has prescribed fusidic acid, the doctor may ask you to temporarily stop taking Simtil 10 mg Tablet 10's to treat your infection. Your doctor will decide when it is safe to restart treatment with Simtil 10 mg Tablet 10's.

Simtil 10 mg Tablet 10's might cause muscle problems, particularly when taken at high doses. In rare conditions, Simtil 10 mg Tablet 10's might cause serious muscle problems such as rhabdomyolysis (muscle tissue breakdown). Consult your doctor immediately if you experience muscle pain, weakness, and tenderness, especially if associated with fever or tiredness.

Simtil 10 mg Tablet 10's may cause side effects such as nausea, headache, stomach pain, and constipation. If these side effects persist or worsen, please consult your doctor.

Swallow Simtil 10 mg Tablet 10's as a whole. Do not crush or break while taking Simtil 10 mg Tablet 10's.

You are recommended to avoid alcohol consumption while taking Simtil 10 mg Tablet 10's as it may increase dizziness and also increase the risk of muscle breakdown. If you have still have any concerns regarding this, please discuss with your doctor.

Take Simtil 10 mg Tablet 10's as advised by your doctor. It is usually taken once a day mostly after dinner. Try to take Simtil 10 mg Tablet 10's at the same time every day for effective results and to remember taking it.

You should take Simtil 10 mg Tablet 10's for as long as it is advised by your doctor. You might need to take it lifelong as cholesterol levels will be maintained only while you are taking Simtil 10 mg Tablet 10's. If you stop Simtil 10 mg Tablet 10's without starting other treatment, your cholesterol levels may increase again. Therefore, do not stop taking it without first consulting your doctor.

You should avoid foods rich in calories like junk food and fried food. It is recommended to eat a low-cholesterol diet and a low-fat. Make sure to follow all the exercise and dietary recommendations made by your dietician or doctor.

Yes, Simtil 10 mg Tablet 10's can make you feel tired. Additionally, Simtil 10 mg Tablet 10's may cause muscle damage which further worsens the tiredness. Therefore, if you feel tired while taking Simtil 10 mg Tablet 10's, consult your doctor.

Yes, Simtil 10 mg Tablet 10's is safe to take in prescribed dose and duration. The patient should follow doctor’s recommendations. Do not exceed the recommended daily dose.

Country of origin

India
Other Info - SI37210

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.542.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019766s085lbl.pdf
  3. https://www.nhs.uk/medicines/simvastatin/
  4. https://www.drugs.com/simvastatin.html
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