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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Sinex Plus Tablet is used to treat the common cold and allergic symptoms such as sneezing, watery eyes or itchy/watery nose and throat, as well as to relieve cough associated with cold and flu. It works by blocking the action of histamine, a substance responsible for causing allergic reactions, thereby relieving allergy symptoms and constricting nasal blood vessels to reduce congestion. Additionally, it suppresses cough by reducing activity in the brain’s cough centre, providing relief. Some people may experience drowsiness, nausea, fatigue, dizziness, nervousness, dryness in the mouth, headache, stomach pain, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sinex Plus Tablet

Sinex Plus Tablet belongs to a category of  'cough and cold medications' primarily used to treat the common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat, as well as to relieve cough associated with cold and flu. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets when a sick person sneezes, coughs or talks. A dry cough is a persistent cough that does not produce mucus or phlegm. It is commonly triggered by viral infections, asthma, allergies, acid reflux, or environmental irritants like smoke and dust. Unlike a wet cough, it often causes a tickling or irritating sensation in the throat.

Sinex Plus Tablet contains Cetirizine (antihistamine/anti allergic), Dextromethorphan (antitussive), Paracetamol (mild analgesic and antipyretic), and Phenylephrine (decongestant). Cetirizine belongs to the class of antihistamines (antiallergic drugs) that work by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, runny nose, watery eyes, itching, swelling, congestion, or stiffness. Dextromethorphan helps suppress cough by reducing activity in the brain’s cough centre, providing relief. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Together, they can effectively treat symptoms of the common cold, flu, allergies, and respiratory infections, including runny nose, sneezing, watery eyes, nasal congestion, cough, fever, and body aches.

Sinex Plus Tablet should be taken as prescribed by the doctor. Your doctor will recommend how often you take Sinex Plus Tablet based on your medical condition. Some people may experience drowsiness, nausea, fatigue, dizziness, nervousness, dryness in the mouth, headache, stomach pain, and vomiting. Everyone doesn't need to experience the above side effects. Most of these side effects of Sinex Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting Sinex Plus Tablet . Let your doctor know if you have emphysema, chronic bronchitis, high blood pressure (hypertension),  liver or kidney disease, or coronary artery disease (heart disease) before taking Sinex Plus Tablet to rule out potential interactions. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Sinex Plus Tablet if you have taken an MAO inhibitor (antidepressant medication like Isocarboxazid, Phenelzine, Selegiline and Tranylcypromine) in the last 14 days. Sinex Plus Tablet can make you dizzy or drowsy, so do not drive or operate heavy machinery after taking Sinex Plus Tablet until you are fully alert.

Uses of Sinex Plus Tablet

Sinex Plus Tablet is used to treat Cough, allergies (allergic rhinitis), and common cold.

Directions for Use

Swallow Sinex Plus Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Sinex Plus Tablet is primarily used to treat the common cold, allergies (allergic rhinitis), and related symptoms such as runny or blocked nose, sneezing, congestion, pain, fever, and cough by suppressing the cough reflex. It is composed of four medicines, namely, Cetirizine (antihistamine/antiallergic), Dextromethorphan (anti-tussive), Paracetamol (mild analgesic and antipyretic), and Phenylephrine (decongestant). Cetirizine belongs to the class of antihistamines (antiallergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Dextromethorphan helps suppress cough by reducing activity in the brain’s cough centre, providing relief. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Together, they can effectively treat symptoms of the common cold, flu, allergies, and respiratory infections, including runny nose, sneezing, watery eyes, nasal congestion, cough, fever, and body aches.

How Sinex Plus Tablet Works

Sinex Plus Tablet contains Cetirizine (antihistamine/anti-allergic), Dextromethorphan (antitussive), Paracetamol (mild analgesic and antipyretic), and Phenylephrine (decongestant). Cetirizine belongs to the class of antihistamines (antiallergic drugs) that work by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, runny nose, watery eyes, itching, swelling, congestion, or stiffness. Dextromethorphan helps suppress cough by reducing activity in the brain’s cough centre, providing relief. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Sinex Plus Tablet

Do not take more than the prescribed dose of Sinex Plus Tablet as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sinex Plus Tablet if you are allergic to Sinex Plus Tablet or any of its ingredients. Please inform your doctor if you are pregnant or breastfeeding before starting Sinex Plus Tablet . If you have high blood pressure, emphysema, chronic bronchitis, kidney or liver disease, or coronary artery disease, please inform your doctor before taking Sinex Plus Tablet to rule out potential interactions. Also, inform your doctor about all other medications you have taken before starting Sinex Plus Tablet . Do not stop taking Sinex Plus Tablet , even if you feel better, without asking your doctor, as your symptoms may come back and even worsen your condition. Sinex Plus Tablet may cause drowsiness and sleepiness, so it is advised not to drive or operate heavy machinery until you are fully alert. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Sinex Plus Tablet if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days. Also, avoid tobacco consumption as it may worsen your condition further.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Sinex Plus Tablet:
Co-administration of Sinex Plus Tablet with Sevoflurane can increase the levels of Sinex Plus Tablet and lead to side effects.

How to manage the interaction:
Taking Sinex Plus Tablet with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Sinex Plus Tablet:
Taking Tranylcypromine with Sinex Plus Tablet can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Sinex Plus Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Sinex Plus Tablet:
Taking Furazolidone with Sinex Plus Tablet can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Sinex Plus Tablet is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Sinex Plus Tablet only after 14 days of stopping Furazolidone.
How does the drug interact with Sinex Plus Tablet:
Taking Sinex Plus Tablet with Propofol may lead to increased levels of Sinex Plus Tablet leading to side effects like high blood pressure.

How to manage the interaction:
Taking Sinex Plus Tablet with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Sinex Plus Tablet:
Co-administration of Selegiline with Sinex Plus Tablet together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Sinex Plus Tablet is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Sinex Plus Tablet:
Co-administration of Isocarboxazid with Sinex Plus Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Sinex Plus Tablet and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Sinex Plus Tablet:
Taking Rasagiline with Sinex Plus Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Sinex Plus Tablet with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Sinex Plus Tablet:
Co-administration of Sinex Plus Tablet and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Sinex Plus Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Sinex Plus Tablet:
Taking Tranylcypromine with Sinex Plus Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Sinex Plus Tablet with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Sinex Plus Tablet:
Co-administration of Sinex Plus Tablet and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Sinex Plus Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • To improve overall health, eat plenty of foods rich in good bacteria, like yoghurt.
  • Drink plenty of fluids to avoid dehydration.
  • Stay away from dust, irritants, and strong odors.
  • Drink warm water, herbal teas, and broths to ease congestion.
  • Gargle with salt water for relief from a sore throat.
  • Avoid alcohol consumption with Sinex Plus Tablet , as it may cause drowsiness, tiredness, or lack of concentration.
  • Wash your hands with soap and water regularly to prevent the spread of germs.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Sinex Plus Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol with Sinex Plus Tablet , as it may increase drowsiness. Please consult a doctor before consuming alcohol with Sinex Plus Tablet .

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Pregnancy

Caution

The safety of Sinex Plus Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Sinex Plus Tablet in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Sinex Plus Tablet may cause drowsiness or dizziness. Therefore, avoid driving or operating heavy machinery unless you are fully alert.

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Liver

Caution

Take Sinex Plus Tablet with caution in case of liver impairment. Please inform your doctor if you have liver disease before taking Sinex Plus Tablet .

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Kidney

Caution

Take Sinex Plus Tablet with caution, especially if you have a history of kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Caution

Sinex Plus Tablet is not recommended for children below 12 years of age. However, please consult a doctor before giving Sinex Plus Tablet to children.

Have a query?

FAQs

Sinex Plus Tablet is used to treat common colds, allergies (allergic rhinitis), and cough relief by suppressing the cough reflex.

Sinex Plus Tablet contains Cetirizine (antihistamine/anti-allergic), Dextromethorphan (antitussive), Paracetamol (mild analgesic and antipyretic), and Phenylephrine (decongestant). Cetirizine belongs to the class of antihistamines (antiallergic drugs) that work by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, runny nose, watery eyes, itching, swelling, congestion, or stiffness. Dextromethorphan helps suppress cough by reducing activity in the brain’s cough centre, providing relief. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Together, they can effectively treat symptoms of the common cold, flu, allergies, and respiratory infections, including runny nose, sneezing, watery eyes, nasal congestion, cough, fever, and body aches.

Yes, Sinex Plus Tablet may cause dry mouth as a common side effect. If you experience this symptom, drink plenty of fluids or water to stay hydrated, sip on sugar free drinks and herbal teas, suck on sugar free candies, limit caffeine, and alcohol, and avoid spicy, salty and acidic foods.

No, you are not recommended to take Sinex Plus Tablet with warfarin as co-administration of these two medicines may increase the bleeding risk. However, please consult a doctor immediately if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately for safe use.

It is not recommended to take Sinex Plus Tablet along with any antidepressant medication as it contains phenylephrine, which is contraindicated with antidepressant medications, especially MAO inhibitors. Also, Sinex Plus Tablet should be taken at least 15 days after your last dose of antidepressants.

Yes, the Sinex Plus Tablet may cause drowsiness. It is not necessary for everyone taking Sinex Plus Tablet to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Sinex Plus Tablet .

Sinex Plus Tablet may cause side effects like drowsiness, nausea, fatigue, dizziness, nervousness, dryness in the mouth, headache, stomach pain, and vomiting. Most of these side effects of Sinex Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (India).
Other Info - SIN0197

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