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  3. Sisflozin-M 12.5/500 Tablet 10's

Sisflozin-M 12.5/500 Tablet 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Sisflozin-M 12.5/500 Tablet 10's is used to treat type 2 diabetes. It works by removing excess sugar from the body through urine and increasing the body’s sensitivity to insulin. It helps lower blood sugar levels and prevents the complications of diabetes. In some cases, this medicine may cause side effects such as frequent urination, mild skin rash or itchy skin, nausea, vomiting or diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

EMPAGLIFLOZIN-12.5MG + METFORMIN-500MG

Manufacturer/Marketer :

Siskan Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sisflozin-M 12.5/500 Tablet 10's

Sisflozin-M 12.5/500 Tablet 10's is used to treat Type 2 diabetes. Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups to lead a normal life.

Sisflozin-M 12.5/500 Tablet 10's is composed of Empagliflozin and Metformin. This medicine works by blocking the sodium-glucose co-transporter-2 (SGLT-2) enzyme. This lowers renal reabsorption of glucose and increases urine excretion of glucose via inhibiting SGLT2.

In some cases, you may experience certain common side effects, such as frequent urination, mild skin rash or itchy skin, or diarrhoea, stomach ache, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. The dosage is based on your medical condition and response to treatment. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsens (if your blood sugar is too high or too low).

Do not consume Sisflozin-M 12.5/500 Tablet 10's if you are allergic to any component present in Sisflozin-M 12.5/500 Tablet 10's. If you are pregnant or breastfeeding, consult your doctor before taking Sisflozin-M 12.5/500 Tablet 10's. Avoid drinking alcohol while taking Sisflozin-M 12.5/500 Tablet 10's since it may produce unpleasant side effects. Inform your doctor about all of the medications you are taking, as well as your medical history, to rule out any undesirable side effects or interactions. Sisflozin-M 12.5/500 Tablet 10's should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease.

Uses of Sisflozin-M 12.5/500 Tablet 10's

Sisflozin-M 12.5/500 Tablet 10's is used for the treatment of Type 2 diabetes mellitus. The detailed uses of Sisflozin-M 12.5/500 Tablet 10's are as follows: <br/>
• Management of Type 2 diabetes: Sisflozin-M 12.5/500 Tablet 10's helps to manage type 2 diabetes by lowering blood sugar levels and improving glycemic control.<br/>
• Cardiovascular benefits: Sisflozin-M 12.5/500 Tablet 10's also offers cardiovascular benefits by reducing the risk of heart attacks, strokes, and other cardiovascular events in patients with type 2 diabetes and heart disease.<br/>
• Weight management: Sisflozin-M 12.5/500 Tablet 10's can aid in weight loss by causing the body to excrete excess glucose through urine, leading to a reduction in body weight.<br/>
• Renal protection: Sisflozin-M 12.5/500 Tablet 10's may be involved in protecting kidney function in patients with type 2 diabetes, slowing the progression of diabetic kidney disease.<br/>
• Lowering blood pressure: Sisflozin-M 12.5/500 Tablet 10's can also help in lowering blood pressure levels, providing additional benefits for patients with diabetes and hypertension.<br/>

Directions for Use

• Sisflozin-M 12.5/500 Tablet 10's should be taken with meals to prevent stomach upset. • It is recommended to take Sisflozin-M 12.5/500 Tablet 10's twice daily at the same time each day or as prescribed by your doctor. • Swallow Sisflozin-M 12.5/500 Tablet 10's as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

  • Sisflozin-M 12.5/500 Tablet 10's is composed of two antidiabetic medicines:
  • It reduces blood sugar levels in people with diabetes. It does this by helping remove excess sugar from your body through your pee.
  • Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients.
  • It lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively.
  • Sisflozin-M 12.5/500 Tablet 10's also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy) or even loss of a foot.

How Sisflozin-M 12.5/500 Tablet 10's Works

Sisflozin-M 12.5/500 Tablet 10's is composed of two antidiabetic medicines: Empagliflozin and Metformin. Empagliflozin is a type of medicine known as a sodium-glucose co-transporter-2 (SGLT2) inhibitor. It reduces blood sugar levels in people with diabetes. It does this by helping remove excess sugar from your body through your pee. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively.

Storage

• Store in a cool and dry place away from sunlight.• Keep Sisflozin-M 12.5/500 Tablet 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Sisflozin-M 12.5/500 Tablet 10's

Take Sisflozin-M 12.5/500 Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Overdose of Sisflozin-M 12.5/500 Tablet 10's may cause lactic acidosis. Symptoms may include trouble breathing, unusual muscle pain, weakness, and irregular heartbeats. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Before taking this medication, tell your doctor or pharmacist if you are allergic to empagliflozin and Metformin, or have other allergies.
  • This product may contain inactive ingredients that can cause allergic reactions or other adverse effects.
  • Sisflozin-M 12.5/500 Tablet 10's should not be stopped even if you feel better, without consulting your doctor, as your sugar level keeps changing.
  • If you stop taking Sisflozin-M 12.5/500 Tablet 10's abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).
  • Sisflozin-M 12.5/500 Tablet 10's should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease.
  • It's generally not recommended to take empagliflozin during pregnancy/breastfeeding. Discuss the risks and benefits with your doctor.
  • Sisflozin-M 12.5/500 Tablet 10's is only for adults (from 18 years). It is not recommended for anyone aged 85 years or older.
  • It may be harder to control your blood sugar when your body is stressed (such as when you have a fever, infection, injury, or surgery). 
  • Also, if you eat less or cannot eat due to these conditions or any illness, this can lead to other side effects while taking this medication. 

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Sisflozin-M 12.5/500 Tablet 10's more than once per day. Do not use other over-the-counter medicines, herbal or vitamin supplements without informing your pharmacist or doctor when you take Sisflozin-M 12.5/500 Tablet 10's.
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include reducing sugars and fatty foods and avoiding carbonated drinks and foods that cause gas.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Sisflozin-M 12.5/500 Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.

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Pregnancy

Caution

Empagliflozin in Sisflozin-M 12.5/500 Tablet 10's is not generally recommended in pregnancy. It is not clear whether empagliflozin can harm an unborn baby. Your doctor may suggest other medications to control your blood sugar levels. Please consult your doctor before starting the Sisflozin-M 12.5/500 Tablet 10's if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Sisflozin-M 12.5/500 Tablet 10's may be unsafe to use during breastfeeding since it is excreted into breast milk. Please seek medical advice for further information.

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Driving

Caution

You’re driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

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Liver

Caution

Inform your doctor before receiving Sisflozin-M 12.5/500 Tablet 10's if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving Sisflozin-M 12.5/500 Tablet 10's if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Sisflozin-M 12.5/500 Tablet 10's is not recommended for people younger than 18 years of age.

Have a query?

FAQs

Sisflozin-M 12.5/500 Tablet 10's is used to treat Type 2 diabetes, a condition that causes the level of glucose (sugar) in the blood to become too high.

Sisflozin-M 12.5/500 Tablet 10's is composed of two antidiabetic medicines: Empagliflozin and Metformin. Empagliflozin works by increasing the amount of sugar that leaves your body in your pee. Metformin lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively.

Your doctor may advise Sisflozin-M 12.5/500 Tablet 10's with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to control blood sugar levels while using Sisflozin-M 12.5/500 Tablet 10's with or without other antidiabetic drugs.

It is not recommended to use Sisflozin-M 12.5/500 Tablet 10's along with diuretics. Simultaneous use of Sisflozin-M 12.5/500 Tablet 10's with diuretics can cause dehydration, and may these can increase your risk of dehydration and lower your blood pressure.

Diabetes is normally treated for the rest of one&amp;#039;s life. Do not discontinue taking Sisflozin-M 12.5/500 Tablet 10's pills without first consulting your doctor.

It is safe to take empagliflozin for a long time. There is no proof that this medication is harmful to your overall health.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

There is no cure for diabetes. Sisflozin-M 12.5/500 Tablet 10's only helps to control type 2 diabetes. However, it is advised to maintain proper diet and exercise along with Sisflozin-M 12.5/500 Tablet 10's to control blood sugar levels.

You should take Sisflozin-M 12.5/500 Tablet 10's with or without food or as prescribed by your doctor. Do not change the dose or prolong the duration of intake.

Country of origin

India

Manufacturer/Marketer address

Maninagar, Ahmedabad(Gujarat).
Other Info - SIS0085

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 26, 2025 | 6:56 PM IST

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Reference

  1. https://www.nhs.uk/medicines/empagliflozin/#:~:text=Empagliflozin%20is%20a%20type%20of,your%20body%20through%20your%20pee.
  2. https://www.nhs.uk/medicines/metformin/

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