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compositionComposition:DAPAGLIFLOZIN-5MG+SITAGLIPTIN-50MG
prescriptionPrescription Medicine
Sitaclass D 50/5 Tablet 10's

Sitaclass D 50/5 Tablet is used to treat type-2 diabetes mellitus. It contains Dapagliflozin and Sitagliptin. Dapagliflozin lowers blood glucose levels and increases glucose excretion in the urine. By improving insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces. Thus, it helps control blood sugar levels. Common side effects of this medicine include diarrhoea, hypoglycaemia, headache, nausea, and vomiting.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DAPAGLIFLOZIN-5MG+SITAGLIPTIN-50MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sitaclass D 50/5 Tablet

Sitaclass D 50/5 Tablet is used to treat Type 2 diabetes. Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups to lead a normal life.

Sitaclass D 50/5 Tablet contains Dapagliflozin and Sitagliptin. This medicine works by increasing the removal of sugar by your kidneys. Linagliptin works by increasing levels of natural substances called incretins. Incretins help regulate blood sugar levels by stimulating insulin release, particularly after meals. They also decrease the amount of sugar your liver makes.

Not everyone who is taking Sitaclass D 50/5 Tablet will get these side effects. In some cases, you may experience certain common side effects, such as frequent urination, dizziness, or light-headedness. To reduce the risk of dizziness and light-headedness, get up slowly when rising from a sitting or lying position. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. The dosage is based on your medical condition and response to treatment. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsens (if your blood sugar is too high or too low).

Before taking this medication, tell your doctor or pharmacist if you are allergic to empagliflozin or linagliptin; or have other allergies. Sitaclass D 50/5 Tablet should not be stopped even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Sitaclass D 50/5 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss, kidney damage, and nerve damage. Sitaclass D 50/5 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Consult the doctor if you are pregnant or breastfeeding.

It is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, limb loss, and sexual dysfunction. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Uses of Sitaclass D 50/5 Tablet

Sitaclass D 50/5 Tablet is used in the treatment of Type-2 diabetes mellitus. The detailed uses of Sitaclass D 50/5 Tablet are as follows:

  • Control blood sugar levels: Sitaclass D 50/5 Tablet helps lower elevated blood glucose in adults with type 2 diabetes, especially when diet, exercise, and other medications alone are not enough.
  • Combination therapy: Sitaclass D 50/5 Tablet improves insulin sensitivity, reduce glucose production in the liver, and increase glucose excretion through urine.
  • Reduce risk of diabetes-related complications: By maintaining better glycemic control, Sitaclass D 50/5 Tablet may help lower the risk of long-term complications like kidney damage, nerve issues, and cardiovascular events.

Key Benefits

  • Sitaclass D 50/5 Tablet helps treat type 2 diabetes, along with a balanced diet and regular exercise. It works by removing excess sugar from the body through urine.
  • It helps control the rise of blood sugar levels in your body after a meal.
  • Sitaclass D 50/5 Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.
  • This medicine is also used to treat chronic kidney disease in adults with reduced kidney function. It helps protect your kidneys from losing their function, which may help some people live longer.
Side effects of Sitaclass D 50/5 Tablet
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Consult your doctor about alternative medications if side effects occur.
  • Ensure adequate intake of food rich in vitamin B12, such as meat, poultry, seafood (salmon and cod), dairy, and eggs.
  • Consider a Vitamin B12 supplement, but consult your doctor for the proper dosage.
  • Avoid drinking too much alcohol.
  • Schedule regular doctor visits to monitor your B12 levels.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Take Sitaclass D 50/5 Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Sitaclass D 50/5 Tablet Works

Sitaclass D 50/5 Tablet contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors) and Sitagliptin (dipeptidyl peptidase-4 inhibitor). Dapagliflozin lowers blood glucose levels and increases the excretion of glucose in the urine. By increasing insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces. Thus, Sitaclass D 50/5 Tablet helps control blood sugar levels.
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Alcohol

Unsafe

Avoid consumption of alcohol during treatment with Sitaclass D 50/5 Tablet as it may cause serious side effects.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before starting treatment with Sitaclass D 50/5 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Sitaclass D 50/5 Tablet on breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking Sitaclass D 50/5 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Sitaclass D 50/5 Tablet may occasionally cause dizziness. Hence, drive only if you are alert after taking this medicine.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Sitaclass D 50/5 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Sitaclass D 50/5 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Sitaclass D 50/5 Tablet is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

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Heart

Safe

Sitaclass D 50/5 Tablet is safe to be used in heart conditions. This medicine shows potential benefits in patients with heart failure and other associated conditions.

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Geriatrics

Safe

Sitaclass D 50/5 Tablet is not generally contraindicated in elderly patients, but caution is advised, and it should be used with careful consideration of potential risks and benefits.

What if I have taken an overdose of Sitaclass D 50/5 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Sitaclass D 50/5 Tablet may include hypoglycemia and severe gastrointestinal problems. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Eat foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Follow a healthy diet and walk/exercise for at least 45 minutes.
  • Maintain a healthy weight by exercising regularly.
  • Rest properly and avoid stress by doing meditation or yoga.

Have a query?

How Soon It Starts Working

The time required for Sitaclass D 50/5 Tablet to start to work: Sitaclass D 50/5 Tablet ideally shows its action within few hours after administration. The time for which the effects of Sitaclass D 50/5 Tablet last: The effect of Sitaclass D 50/5 Tablet lasts for 24 hours.

What if you forget to take Sitaclass D 50/5 Tablet

If you miss a dose of Sitaclass D 50/5 Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Sitaclass D 50/5 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Before taking this medication, tell your doctor or pharmacist if you are allergic to any of its contents. 
  • Sitaclass D 50/5 Tablet should not be stopped even if you feel better, without consulting your doctor, as your sugar level keeps changing. If you stop taking Sitaclass D 50/5 Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). 
  • Please inform your doctor if you have heart disease.
  • It may be harder to control your blood sugar when your body is stressed (such as when you have a fever, infection, injury, or surgery). 
  • Also, if you eat less or cannot eat due to these conditions or any illness, this can lead to other side effects while taking this medication. 
  • Before surgery, tell your doctor or dentist about all the products you use (including prescription, nonprescription, and herbal products).
  • Be alert for signs of low blood sugar (hypoglycemia), such as sweating, dizziness, dry mouth, dry skin, fast heartbeat, shivering, intense thirst, or frequent urination. If you experience any of these symptoms, take honey or sugar candies right away.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Sitaclass D 50/5 Tablet may interact with anti-diabetic (insulin glargine), diuretics (furosemide), hormone (levothyroxine) and corticosteroids.

Drug-Food Interactions: Avoid alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have hypoglycaemia (low blood sugar levels), heart problems and liver/kidney disease.

Sitagliptin + MetforminIopamidol
Critical
Sitagliptin + MetforminIomeprol
Critical

Drug-Drug Interactions

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Sitagliptin + MetforminIopamidol
Critical
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Iopamidol with Sitaclass D 50/5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaclass D 50/5 Tablet with Iopamidol is not recommended, please consult a doctor before taking it.
Sitagliptin + MetforminIomeprol
Critical
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Iomeprol with Sitaclass D 50/5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaclass D 50/5 Tablet with Iomeprol is not recommended, please consult a doctor before taking it.
Sitagliptin + MetforminIopromide
Critical
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Iopromide with Sitaclass D 50/5 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Sitaclass D 50/5 Tablet is not recommended, please consult a doctor before taking it.
Sitagliptin + MetforminGatifloxacin
Critical
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Sitaclass D 50/5 Tablet with Gatifloxacin can cause both hypoglycemia (low blood glucose) and, less frequently, hyperglycemia (high blood glucose).

How to manage the interaction:
There is a possibility of interaction between Sitaclass D 50/5 Tablet and Gatifloxacin but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms like headache, dizziness, drowsiness, nervousness, confusion, tremors, hunger, weakness, sweating, palpitation, and tachycardia(fast heart rate). Do not discontinue without consulting a doctor.
Sitagliptin + MetforminIodamide
Critical
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Sitaclass D 50/5 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Sitaclass D 50/5 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult a doctor before taking it.
Sitagliptin + MetforminIodixanol
Critical
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Iodixanol with Sitaclass D 50/5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaclass D 50/5 Tablet with Iodixanol is not recommended, please consult a doctor before taking it.
Sitagliptin + MetforminMetrizamide
Critical
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Sitaclass D 50/5 Tablet and Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Sitaclass D 50/5 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, nausea, vomiting, diarrhea, muscle cramps or pain, body weakness, extreme fatigue, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sitagliptin + MetforminAcetazolamide
Severe
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Sitaclass D 50/5 Tablet with Acetazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Sitaclass D 50/5 Tablet and Acetazolamide, you can take these medicines together if prescribed by your doctor. However, if you have symptoms such as weakness, muscle pain, difficulty breathing, dizziness, chest pain or discomfort, fatigue, or loss of appetite, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sitagliptin + MetforminMethazolamide
Severe
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Sitaclass D 50/5 Tablet with Methazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Sitaclass D 50/5 Tablet and Methazolamide, you can take these medicines together if prescribed by your doctor. However, if you have symptoms such as weakness, muscle pain, respiratory distress, fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, or chills, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
Sitagliptin + MetforminEthanol
Severe
How does the drug interact with Sitaclass D 50/5 Tablet:
Co-administration of Sitaclass D 50/5 Tablet with Ethanol may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Sitaclass D 50/5 Tablet and Ethanol, you can take these medicines together if prescribed by your doctor. However, if you have symptoms such as weakness, muscle pain, increased drowsiness, dizziness, stomach pain or discomfort, slow or irregular heartbeat difficulty in breathing, or loss of appetite, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Sitaclass D 50/5 Tablet is used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus (also known as non-insulin-dependent diabetes or adult-onset diabetes) is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.

Low-fibre diets, high-fat diets, sugary diets, obesity, smoking, stress, lack of exercise, age, genetic factors, and certain medical conditions are the common causes of diabetes.

Sitaclass D 50/5 Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin lowers blood glucose levels and increases the excretion of glucose in the urine. By increasing insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces.

Disclaimer

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - SIT0324

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