Sitashine-DM Tablet 10's
MRP ₹215.5
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About Sitashine-DM Tablet
Sitashine-DM Tablet is an antidiabetic medicine used to treat Type II Diabetes. In type 2 diabetes, the pancreas does not produce enough insulin, or the body is unable to use insulin effectively. As a result, blood sugar levels become elevated.
Sitashine-DM Tablet contains Dapagliflozin, Sitagliptin, and Metformin. It works by removing excess sugar from the body through urine, increasing the levels of certain natural substances that lower blood sugar when it is high, reducing sugar production by cells in the liver, and delaying sugar absorption from the intestines.
Take Sitashine-DM Tablet as advised by your doctor. Sitashine-DM Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and stomach upset. Most of these side effects do not need medical attention and resolve over time. If these side effects persist or worsen, please consult your doctor.
Do not take Sitashine-DM Tablet if you are allergic to any of its components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Sitashine-DM Tablet . Let your doctor know if you are pregnant or breastfeeding before taking Sitashine-DM Tablet . It is not recommended for use in children below 18 years of age.
Uses of Sitashine-DM Tablet
Sitashine-DM Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Sitashine-DM Tablet are as follows:
- Type 2 Diabetes Management: Sitashine-DM Tablet is used to improve blood sugar control in adults with type 2 diabetes. It combines three agents that work together to reduce glucose production, enhance insulin response, and promote glucose excretion through urine.
- Cardiovascular and Kidney Protection: Sitashine-DM Tablet helps lower the risk of heart failure and diabetic kidney disease by improving vascular function, reducing albuminuria, and supporting healthy blood pressure levels.
- Weight and Metabolic Control: Sitashine-DM Tablet supports weight loss and improves metabolic health by reducing excess glucose and enhancing insulin sensitivity, making it beneficial for overweight or obese diabetic patients.
- HbA1c Reduction and Glycemic Stability: Sitashine-DM Tablet effectively lowers HbA1c levels and helps maintain steady blood sugar throughout the day, reducing the risk of hypoglycemia and long-term complications.
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Directions for Use
- Take Sitashine-DM Tablet with food to reduce stomach upset or gastrointestinal side effects.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Key Benefits
- Sitashine-DM Tablet is a combination of three antidiabetic medicines: Sitagliptin, Dapagliflozin, and Metformin, used in the management of Type 2 Diabetes Mellitus, along with proper diet and exercise.
- Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase insulin release and decrease glucagon levels in the body, lowering blood sugar levels when they are high.
- Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, works by removing excess glucose through the urine, thereby lowering blood sugar levels.
- Metformin is a biguanide which reduces the amount of sugar produced by the liver and delays glucose absorption from the intestine.
- It improves the body’s sensitivity to insulin, promoting better glucose uptake by muscles and tissues.
- The combined effect of these three drugs offers multi-targeted control of blood sugar levels, especially in patients not controlled by single or dual therapy.
- Sitashine-DM Tablet helps manage blood glucose levels and prevents diabetes-related complications, such as eye problems, nerve problems, and kidney impairment.
How Sitashine-DM Tablet Works
Storage
- Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
- To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
- Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
- Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
- Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
- Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
- If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
- Drink plenty of water and caffeine-free drinks.
- Eat more fibre by consuming fruits, vegetables, and whole grains.
- Avoid processed, spicy, or fatty foods.
- Try not to skip meals, delay eating, or eat too quickly.
- Regular exercise can help improve digestion and promote better stool movement.
- If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
- Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
- Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
- Make medication adjustments as recommended by your doctor to prevent future episodes.
- Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
- Monitor your blood sugar levels closely for patterns and changes.
- Track your progress by recording your blood sugar levels, food intake, and physical activity.
- Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
- Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
- Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
- Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
- Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
- Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
- Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
- Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
What if I have taken an overdose of Sitashine-DM Tablet
Drug Warnings
- Sitashine-DM Tablet should be avoided if you are allergic to any of the components in it.
- Before starting treatment, inform your doctor about your medical history and the medications you are taking, including any herbs and supplements. This can help prevent unwanted effects.
- Sitashine-DM Tablet is not recommended for use in patients with severe liver or kidney disease.
- Consult your doctor if you are pregnant or breastfeeding.
- It is not recommended for use in children below 18 years of age.
- Avoid drinking alcohol while on Sitashine-DM Tablet as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Sitashine-DM Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Gatifloxacin can be taken with Sitashine-DM Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
Co-administration of Iohexol with Sitashine-DM Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Sitashine-DM Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Iodixanol with Sitashine-DM Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Sitashine-DM Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Iopromide with Sitashine-DM Tablet can increase the risk of lactic acidosis.
How to manage the interaction:
Taking Iopromide with Sitashine-DM Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
Co-administration of Sitashine-DM Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).
How to manage the interaction:
Taking Sitashine-DM Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Iopentol with Sitashine-DM Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Sitashine-DM Tablet with Iopentol is not recommended, please consult your doctor before taking it.
Co-administration of Sitashine-DM Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).
How to manage the interaction:
Taking Sitashine-DM Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
Co-administration of Iopanoic acid with Sitashine-DM Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Sitashine-DM Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
Co-administration of Iofendylate with Sitashine-DM Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Sitashine-DM Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Ioglicic acid with Sitashine-DM Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Sitashine-DM Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
- Include whole-grain foods, fruits and veggies, and other fibre-enriched foods.
- Add omega-3 fatty acid-containing oils for daily cooking.
- Avoid too much stress, as it may elevate your blood sugar level. To control stress-related blood sugar changes, you can adopt stress management techniques like mindfulness, meditation, or yoga.
- Weight loss gradually to achieve a healthy body mass index (18.5 to 24.9).
- Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
- Avoid smoking and alcohol consumption while on treatment with Sitashine-DM Tablet .
- Take short, frequent meals, and avoid prolonged fasting when taking Sitashine-DM Tablet .
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Alcohol
Safe if prescribed
Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Sitashine-DM Tablet .
Pregnancy
Consult your doctor
There are no adequate studies on the effect of Sitashine-DM Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Sitashine-DM Tablet .
Breast Feeding
Consult your doctor
Sitashine-DM Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Sitashine-DM Tablet .
Driving
Safe if prescribed
Sitashine-DM Tablet usually does not affect your ability to drive or operate machinery.
Liver
Consult your doctor
Use Sitashine-DM Tablet with caution, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
Consult your doctor
Renal impairment also increases the risk of lactic acidosis. Hence, Sitashine-DM Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Safe if prescribed
Sitashine-DM Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.
Heart
Please consult your doctor before receiving Sitashine-DM Tablet if you have pre-existing heart problems. Your doctor will prescribe Sitashine-DM Tablet if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Please consult a doctor before administering Sitashine-DM Tablet to geriatric patients. Your doctor will prescribe Sitashine-DM Tablet if the benefits outweigh the risks.
FAQs
Sitashine-DM Tablet is used to treat type II diabetes mellitus, a condition wherein the body doesn't use insulin effectively, which causes unusual blood glucose levels.
Sitashine-DM Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.
If you forget to take Sitashine-DM Tablet , take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double-dose to make up the missed dose. Taking an overdose might cause your sugar level to fall rapidly.
Sitashine-DM Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and allergic reactions. If these side effects persist or worsen, please consult your doctor.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022044s022lbl.pdf
- https://medlineplus.gov/druginfo/meds/a606023.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
- https://www.drugs.com/metformin.html
- https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/#:~:text=Sitagliptin%20is%20prescribed%20for%20people,is%20only%20available%20on%20prescription.
