Solonase 1.5MIU Injection

Solonase 1.5MIU Injection belongs to the class of medicines called antifibrinolytic agents. It is used to dissolve blood clots that have formed in the blood vessels in various conditions such as Intravascular dissolution of thrombi and emboli in extensive deep vein thrombosis, Pulmonary embolism, Acute or subacute occlusion of peripheral arteries, Central retinal venous and Arterial thrombosis.

Solonase 1.5MIU Injection contains Streptokinase. Streptokinase creates a highly specific 1:1 enzymatic complex with plasminogen that transforms inactive plasminogen molecules into active plasmin. Plasmin destroys fibrin clots, as well as fibrinogen and other plasma proteins. This, in turn, causes the breakdown of blood clots.

Solonase 1.5MIU Injection should be administered to patients only in a hospital setting by an experienced healthcare professional. Solonase 1.5MIU Injection may cause certain common side effects, including allergic reactions, hypotension, tachycardia, bradycardia, hypotension, heart rate and rhythm disorders, angina pectoris, nausea, diarrhoea, epigastric pain, vomiting, headache, back pain, musculoskeletal pain, chills, fever, asthenia, elevations of serum transaminases and bilirubin. These side effects usually go away on their own. If you develop any other serious side effects, such as vision problems while using Solonase 1.5MIU Injection, consult your doctor immediately.

Solonase 1.5MIU Injection is indicated in adults. Solonase 1.5MIU Injection is not recommended for children below 18 years of age as the safety and effectiveness were not established. Inform your doctor if you are pregnant or planning for pregnancy or breastfeeding since Solonase 1.5MIU Injection is contra-indicated in pregnancy, especially within the first 18 weeks of pregnancy. It is unknown whether Streptokinase is excreted in human milk. Breast milk should be discarded during the first 24 hours following thrombolytic therapy.

Solonase 1.5MIU Injection is used to dissolve blood clots that have formed in the blood vessels and Treatment of Pulmonary embolism, Acute or subacute occlusion of peripheral arteries, Central retinal venous, and Arterial thrombosis. The detailed uses of Solonase 1.5MIU Injection are as follows:

• Treat acute myocardial infarction (heart attack): Solonase 1.5MIU Injection dissolves clots in coronary arteries, restoring blood flow to the heart muscle and reducing damage when administered within hours of symptom onset.
• Manage pulmonary embolism: Solonase 1.5MIU Injection breaks down clots in the lungs, improving oxygen exchange and reducing the risk of life-threatening complications.
• Treat deep vein thrombosis (DVT): Solonase 1.5MIU Injection helps dissolve clots in deep veins, typically in the legs, preventing progression to pulmonary embolism.
• Address arterial thrombosis and embolism: Solonase 1.5MIU Injection is used to lyse clots in arteries that may cause strokes or limb ischemia, improving circulation and preventing tissue damage.

• Follow your doctor’s instructions on the dosage and timing of this medication, to improve effectiveness.
• Solonase 1.5MIU Injection will be administered by a healthcare professional.
• Do not self-administer it.

Solonase 1.5MIU Injection contains ‘Streptokinase’, which belongs to the class of anti-fibrinolytic agents. It acts by regulating the breakdown of blood clots in the body. It blocks the release and action of plasmin, an enzyme essential for the breakdown of clots in the blood. This effect helps to slow down abnormal bleeding.

Before taking Solonase 1.5MIU Injection, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Usage of Solonase 1.5MIU Injection contraindicated to use in persons with certain medical conditions that cause risk of bleeding such as existing or recent internal haemorrhage (internal bleeding), recent cerebrovascular accident, intracranial or intraspinal surgery, intracranial neoplasm (brain tumour), recent head trauma, arteriovenous malformation (an abnormal connection between arteries and veins), neoplasm  (a cancerous tumour) with risk of bleeding, pancreas inflammation, severe liver or kidney damage and simultaneous or recent treatment with oral anticoagulants. So, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.