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About Solupleg 20ml Injection
Solupleg 20ml Injection is a cardioprotective medication used to induce cardioplegia during heart surgeries that involve cardiopulmonary bypass. It is commonly used in procedures such as heart valve replacement and heart transplants to keep a donated heart safe. Cardioplegia is a treatment administered during heart surgeries to deliberately and temporarily stop the heart, helping to protect the heart muscle (myocardium).
Solupleg 20ml Injection contains Magnesium chloride (an electrolyte), Potassium chloride (an electrolyte), and Procaine (a local anaesthetic). Magnesium Chloride and Potassium Chloride lower the heart's oxygen demand by calming its electrical activity, which prevents muscle damage during heart surgery. Procaine decreases the sensation of pain by blocking the transmission of nerve impulses.
A trained healthcare professional will administer Solupleg 20ml Injection through an infusion during surgery; do not self-administer. Consult the doctor immediately if you experience unusual symptoms after surgery, such as nausea, muscle twitching, tremors, convulsions, or irregular/slow heartbeat.
Before receiving Solupleg 20ml Injection, inform your doctor if you are allergic to any of its ingredients. Also, let your doctor know if you are taking any prescription or non-prescription medications, vitamins, and herbal supplements or have any pre-existing medical conditions to rule out any side effects or interactions. Please consult your doctor if you are pregnant or breastfeeding before receiving Solupleg 20ml Injection.
Uses of Solupleg 20ml Injection
Solupleg 20ml Injection is used to induce cardioplegia during heart surgery. The detailed uses of Solupleg 20ml Injection are as follows:

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Medicinal Benefits
Solupleg 20ml Injection is a cardioprotective medication used to induce cardioplegia (temporarily stop the heart) during heart surgeries that involve cardiopulmonary bypass. It is commonly used in procedures such as heart valve replacement and heart transplants to keep a donated heart safe. It contains Magnesium chloride, Potassium chloride, and Procaine. Potassium chloride works by increasing potassium levels, which causes the heart muscle to contract. This action triggers the release of calcium ions, temporarily pausing the activity of the heart. Magnesium chloride also works by reducing the heart’s contractions. Together, they lower the heart's oxygen demand by calming its electrical activity, which prevents muscle damage while the heart is temporarily stopped during surgery. Procaine works by blocking the transmission of nerve impulses, which helps decrease the sensation of pain.
How Solupleg 20ml Injection Works
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What if I have taken an overdose of Solupleg 20ml Injection
Drug Warnings
Before receiving Solupleg 20ml Injection, inform your doctor if you are allergic to any of its ingredients. Also, let your doctor know if you are taking any prescription or non-prescription medications, vitamins, and herbal supplements or have any pre-existing medical conditions to rule out any side effects or interactions. It is not known whether Solupleg 20ml Injection can harm an unborn baby during pregnancy or pass into breast milk during breastfeeding. Therefore, please consult your doctor if you are pregnant or breastfeeding before receiving Solupleg 20ml Injection.
Drug-Drug Interactions
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Habit Forming
Therapeutic Class
Alcohol
Consult your doctor
It is not known if alcohol interacts with Solupleg 20ml Injection. Please consult your doctor before consuming alcohol.
Pregnancy
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There is no information available about the use of Solupleg 20ml Injection during pregnancy. Please consult your doctor if you have any concerns regarding the use of Solupleg 20ml Injection during pregnancy.
Breast Feeding
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It is not known if Solupleg 20ml Injection passes into breastmilk. Please consult your doctor if you have any concerns regarding the use of Solupleg 20ml Injection during breastfeeding.
Driving
Caution
Avoid driving and operating machinery until your doctor confirms that it is safe to do so.
Liver
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Please consult your doctor before receiving Solupleg 20ml Injection if you have liver problems.
Kidney
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Please consult your doctor before receiving Solupleg 20ml Injection if you have kidney problems.
Children
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Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Solupleg 20ml Injection in children.
Heart
Inform your doctor if you have heart problems before using Solupleg 20ml Injection.
Geriatrics
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Solupleg 20ml Injection can be given to geriatrics. If you have any concerns regarding the use of Solupleg 20ml Injection, please consult a doctor.
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