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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ONDANSETRON-2MG/5ML

Manufacturer/Marketer :

Indoco Remedies Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Speronden 2mg/5ml Syrup

Speronden 2mg/5ml Syrup is a medication prescribed to prevent and treat nausea and vomiting. It is primarily used to help patients managing stomach upset caused by cancer chemotherapy, radiation therapy, or surgical procedures. This medicine helps manage these challenging symptoms so you can focus on your recovery.

Your doctor will determine how often you should take this medicine, which is typically taken consistently before your medical treatment begins. It can be taken safely with or without food. To get the best results, you can combine this treatment with simple lifestyle adjustments, such as eating small, frequent meals and keeping hydrated with clear liquids throughout the day.

While taking Speronden 2mg/5ml Syrup, some people may experience mild and temporary side effects such as headaches, constipation, or a warm, flushed feeling. While these are common and usually resolve on their own, you must consult your doctor immediately if you experience severe side effects, such as a rapid or irregular heartbeat, severe dizziness, or fainting.

Before starting this medication, talk to your doctor if you have a history of liver damage, heart rhythm conditions, or imbalances of potassium or magnesium in your blood. Do not take this if you are currently taking apomorphine, as the combination can cause a dangerous drop in blood pressure.

This medicine can interact with other substances, including certain antidepressants, which can lead to serious nervous system complications. It is also important to limit alcohol, as it can worsen dizziness and stomach upset. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of Speronden 2mg/5ml Syrup

Speronden 2mg/5ml Syrup may be prescribed for the following conditions: 

  • Chemotherapy-induced nausea and vomiting: This medicine helps prevent and manage severe stomach upset and vomiting triggered by cancer chemotherapy treatments.
  • Radiation therapy-induced nausea and vomiting: It is used to control nausea in patients undergoing radiation therapy, particularly treatments directed at the abdomen.
  • Post-operative nausea and vomiting: It prevents and treats the nausea and vomiting that commonly occur in patients waking up from anaesthesia after surgery.

Key Benefits

Speronden 2mg/5ml Syrup helps prevent and control nausea and vomiting caused by medical treatments, surgery, or other conditions. It works by blocking signals that trigger the urge to vomit, helping improve comfort and recovery.

  • Prevents Nausea and Vomiting: Helps control nausea and vomiting associated with chemotherapy, radiotherapy, surgery, and other medical conditions.
  • Provides Rapid Symptom Relief: Acts quickly to reduce feelings of nausea and prevent vomiting episodes.
  • Supports Treatment Adherence: Helps patients continue important treatments, such as chemotherapy and radiation therapy, more comfortably.
  • Reduces the Risk of Dehydration: By preventing vomiting, it helps the body retain fluids, nutrients, and prescribed medicines.
  • Promotes Recovery and Comfort: Helps improve overall well-being and supports a smoother recovery after surgery or illness.

Directions for Use

To ensure the medicine works effectively, follow these step-by-step instructions based on your specific oral dosage form:

  • If you are taking regular swallowable tablets, swallow the tablet whole with a full glass of water. You can take it with or without food. Do not crush or chew the tablet.
  • If you are taking disintegrating tablets, ensure your hands are completely dry. Gently peel back the foil backing of the blister pack rather than pushing the tablet through, as the tablet is delicate and can break. Place the tablet directly on your tongue, allow it to dissolve completely, and swallow it with your saliva. You do not need to drink water to take this form.

Always follow your doctor's exact instructions regarding your specific schedule and when to take your dose relative to your treatments.

How Speronden 2mg/5ml Syrup Works

This medicine contains ondansetron, which works by blocking serotonin, a natural chemical in your body that triggers the vomiting reflex. When you undergo chemotherapy, radiation, or surgery, your body releases large amounts of serotonin, which binds to specific receptors in your gut and brain to signal your stomach to vomit. By blocking these specific serotonin receptors, Speronden 2mg/5ml Syrup prevents those chemical signals from reaching the vomiting centre in your brain. This stops the sensation of nausea before it can escalate, giving you effective and reliable control over your symptoms.
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Alcohol

Caution

Alcohol has no known direct interaction with Speronden 2mg/5ml Syrup. However, it is advisable to avoid consuming alcohol while taking Speronden 2mg/5ml Syrup, as it may worsen the side effects like drowsiness.

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Pregnancy

Unsafe

Speronden 2mg/5ml Syrup should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Speronden 2mg/5ml Syrup, as small amounts of the medicine may pass into breast milk.

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Driving

Caution

Speronden 2mg/5ml Syrup does not affect your ability to drive. However, if you experience drowsiness or blurred vision after taking Speronden 2mg/5ml Syrup, avoid driving or operating any heavy machinery.

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Liver

Caution

In individuals with liver problems, the use of Speronden 2mg/5ml Syrup is allowed if prescribed by a doctor. However, patients with severe liver impairment should take a low dose of Speronden 2mg/5ml Syrup as much as possible. Do not take more than 8 mg of Speronden 2mg/5ml Syrup per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Speronden 2mg/5ml Syrup is considered safe in patients with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Speronden 2mg/5ml Syrup should not be given to children below 4 years of age, as its safety and effectiveness have not been established in this age group. The use of Speronden 2mg/5ml Syrup is safe in children above 4 years of age if prescribed by a doctor.

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Heart

Caution

Speronden 2mg/5ml Syrup should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Speronden 2mg/5ml Syrup.

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Geriatrics

Caution

Speronden 2mg/5ml Syrup should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Speronden 2mg/5ml Syrup.

What if I have taken an overdose of Speronden 2mg/5ml Syrup

Do not take more than the prescribed dose of Speronden 2mg/5ml Syrup, as it may lead to an overdose. Symptoms of an overdose may include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness, or light-headedness. If you suspect that you have taken an overdose of this medication or notice any unusual symptoms, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated gradually: Avoid drinking large amounts of liquid all at once. Instead, sip small amounts of water, clear broths, or electrolyte drinks continuously throughout the day.
  • Eat small, frequent meals: Rather than eating three large meals, eat five or six small portions of bland, low-fat foods. Excellent choices include crackers, toast, plain rice, oatmeal, and applesauce.
  • Avoid strong odours: Keep your eating and resting areas well-ventilated. Cooking smells, heavy perfumes, and household chemicals can quickly trigger nausea.
  • Remain upright after eating: Sit up or rest in a comfortable, upright position for at least 30 to 60 minutes after meals to help digestion and prevent acid reflux.

Have a query?

How Soon It Starts Working

  • The time required for Speronden 2mg/5ml Syrup to start to work: Speronden 2mg/5ml Syrup ideally shows its action within 2 hours after administration.
  • The time for which the effects of Speronden 2mg/5ml Syrup last: The effect of Speronden 2mg/5ml Syrup lasts for 12 to 28 hours.

What if you forget to take Speronden 2mg/5ml Syrup

If you forget to take a dose of Speronden 2mg/5ml Syrup, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and take your regular dose. Never take a double dose to make up for a forgotten dose.

Storage

• Store the tablets at room temperature, ideally between 68°F and 77°F (20°C and 25°C). • Keep your medication in a dry place away from direct light and moisture. Do not store this medicine in bathroom cabinets, as high humidity can damage the tablets.

Drug Warnings

  • Check the Dosage Form: Confirm whether you have regular tablets or orally disintegrating tablets, as they should be taken differently.
  • Handle Disintegrating Tablets Carefully: Peel back the foil gently with dry hands and avoid pushing orally disintegrating tablets through the packaging.
  • Use Caution During Activities: Avoid driving or operating machinery if Speronden 2mg/5ml Syrup causes dizziness, drowsiness, or reduced alertness.
  • Manage Constipation: Speak with your doctor or pharmacist about ways to prevent or manage constipation, which can occur during treatment.
  • Inform Healthcare Providers About Other Medicines: Tell your doctor about all medicines, vitamins, and herbal supplements you are taking before starting Speronden 2mg/5ml Syrup.

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Speronden 2mg/5ml Syrup: 

  • Apomorphine: Do not take this medicine if you are using apomorphine (a drug used for Parkinson's disease). Combining them can cause an extreme, dangerous drop in blood pressure and loss of consciousness.
  • Antidepressants (SSRIs and SNRIs): Taking Speronden 2mg/5ml Syrup alongside certain antidepressants can increase the risk of serotonin syndrome, a rare but life-threatening condition that causes high fever, agitation, and muscle stiffness.
  • Heart rhythm medications: Combining this medicine with drugs that alter your heart's electrical activity can increase the risk of irregular heartbeats.


Drug-Food Interactions

The following food or drink may affect your treatment with Speronden 2mg/5ml Syrup: 

  • Alcohol: Avoid drinking alcohol while taking this medicine. Alcohol can significantly worsen side effects like drowsiness and dizziness, and it can further irritate your stomach.


Drug-Disease Interactions

Inform your doctor if you have any of the following conditions before taking Speronden 2mg/5ml Syrup: 

  • Liver damage: If you have severe liver damage, your body may process this medicine much slower than normal. Your doctor may need to prescribe a lower daily dose.
  • Heart conditions: If you have a history of long QT syndrome, heart failure, or irregular heartbeats, use this medicine with extreme caution, as it can affect your heart's electrical rhythm.
  • Electrolyte imbalances: Having low blood levels of potassium or magnesium increases your risk of developing heart rhythm complications while taking this medicine.

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Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Speronden 2mg/5ml Syrup is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery.

Speronden 2mg/5ml Syrup contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

Speronden 2mg/5ml Syrup may cause drowsiness and changes in vision, so avoid driving or operating any machines that require mental alertness.

People with an irregular heartbeat (arrhythmia) and phenylketonuria (too much of the protein phenylalanine in the blood) should not take Speronden 2mg/5ml Syrup as it may cause serious conditions. The patient with liver disease should not take more than 8 mg of Speronden 2mg/5ml Syrup daily. Taking Speronden 2mg/5ml Syrup with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Speronden 2mg/5ml Syrup contains Ondansetron, an antiemetic drug, used in the prevention of vomiting and nausea.

Before taking Speronden 2mg/5ml Syrup, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Also, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Common side effects of Speronden 2mg/5ml Syrup may include constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. However, not every person experiences these side effects, and some of the unpleasant effects of Speronden 2mg/5ml Syrup do not require medical attention. If the side effects persist or worsen, please consult your doctor.

Speronden 2mg/5ml Syrup works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Speronden 2mg/5ml Syrup prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Yes, you can take Speronden 2mg/5ml Syrup half an hour to 1 hour before meals.

If you forget to take a dose of Speronden 2mg/5ml Syrup, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and take your regular dose. Never take a double dose to make up for a forgotten dose.

If you take more than the recommended dose of Speronden 2mg/5ml Syrup, it may result in an overdose. Signs and symptoms of an overdose of Speronden 2mg/5ml Syrup may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

No, Speronden 2mg/5ml Syrup is not a steroid. Speronden 2mg/5ml Syrup belongs to a class of drugs known as antiemetics.

While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.

Take Speronden 2mg/5ml Syrup exactly as prescribed by the doctor. Take it at the same time daily, as it will help you remember to take the medication.

Yes, Speronden 2mg/5ml Syrup can be given during pregnancy if prescribed by a doctor. However, it is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

Yes, you can take this medicine with or without food. If you find that taking it on an empty stomach makes you feel slightly uneasy, try taking your dose with a small snack or a light meal. Talk to your doctor or pharmacist if your nausea makes it difficult to eat.

This medicine generally starts working within 1 to 2 hours after you take it. If you are taking the orally disintegrating tablet, it dissolves rapidly on your tongue and begins absorbing quickly to help keep your symptoms controlled. Talk to your doctor if your nausea does not improve after taking it.

Feeling tired or drowsy is a known, common side effect of this medicine. If you experience drowsiness, lightheadedness, or dizziness, avoid driving, riding a bicycle, or operating tools and machinery. Talk to your doctor if this sleepiness interferes with your daily routine.

You must consult your doctor before using this medicine during pregnancy. While it is sometimes prescribed for severe pregnancy-related nausea, your doctor will carefully evaluate your situation to ensure it is the safest option for both you and your developing baby. Talk to your doctor for personalised advice.

It is highly recommended to avoid alcohol while taking this medicine. Alcohol can worsen side effects like drowsiness, headache, and dizziness, and it can also irritate your stomach lining, which may make your nausea worse. Talk to your doctor if you have questions about alcohol use.

If you vomit shortly after taking your dose, do not take an immediate replacement dose, as you may accidentally absorb too much medicine. Contact your doctor or pharmacist right away for specific, safe instructions on whether to take another dose or wait.

This medicine is generally not effective for motion sickness. It targets chemical pathways in the body associated with chemotherapy, radiation, and surgery rather than the balance centres in the inner ear. Talk to your doctor or pharmacist to find a more appropriate treatment for travel-related nausea.

You should only take this medicine for the exact duration prescribed by your doctor. The duration of treatment depends on the condition being treated and your doctor's recommendation. Some people may use Speronden 2mg/5ml Syrup for a short period around chemotherapy, surgery, or radiation therapy, while others may require treatment for longer. Talk to your doctor if your nausea persists beyond your prescribed treatment days.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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