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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

SPIRONOLACTONE-50MG

Manufacturer/Marketer :

Knoll Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Spironol-50 Tablet 10's

Spironol-50 Tablet 10's is a medicine primarily used to treat high blood pressure, heart failure, and swelling caused by excess fluid in the body (oedema). It helps remove extra water and salt from your body while keeping your potassium levels from dropping too low. This treatment is crucial for reducing the workload on your cardiovascular system.

This medicine is typically taken once or twice a day, and it is highly important to take it consistently at the same time each day. You can take this medicine with or without food, but you should choose one method and stick to it with every dose to ensure even absorption. Adopting a low-salt diet and staying active can significantly support the benefits of this treatment.

While taking Spironol-50 Tablet 10's, you may experience mild side effects like dizziness, headache, or an upset stomach as your body adjusts. However, you must contact your doctor immediately if you experience signs of serious issues, such as an irregular heartbeat, severe muscle weakness, or a severe skin rash.

Talk to your doctor before taking this medicine if you have kidney problems, liver damage, or high potassium levels in your blood. Do not take this if you have Addison's disease, severe kidney failure, or if you are unable to pass urine.

This medicine can interact with other drugs like blood pressure pills, pain relievers, and potassium supplements, which can dangerously increase potassium levels in your body. Do not use Spironol-50 Tablet 10's during pregnancy unless specifically advised by your doctor, as it may affect the development of the unborn baby. If you become pregnant while taking this medicine, inform your doctor immediately. If you are breastfeeding or are an older adult, consult your doctor or pharmacist regarding safe use.

Uses of Spironol-50 Tablet 10's

Spironol-50 Tablet 10's may be prescribed for the following conditions: 

  • High blood pressure (hypertension): Spironol-50 Tablet 10's helps lower blood pressure, which reduces the workload on your heart and blood vessels.
  • Fluid retention (oedema): It assists the body in shedding excess fluid trapped in tissues due to heart, kidney, or liver conditions.
  • Heart failure: By reducing fluid buildup and easing blood pressure, it helps the heart pump blood more efficiently and lowers the risk of hospitalisation.
  • Excess aldosterone (hyperaldosteronism): It treats conditions where the body produces too much of the hormone aldosterone, which causes salt and water retention.
  • Acne and hormonal conditions in women: Spironol-50 Tablet 10's may be prescribed by dermatologists or gynaecologists to help manage acne, excessive hair growth (hirsutism), and symptoms related to polycystic ovary syndrome (PCOS) by reducing the effects of certain male hormones (androgens). 

Key Benefits

Spironol-50 Tablet 10's helps remove excess fluid from the body while lowering blood pressure and maintaining healthy potassium levels. It is commonly used in conditions associated with fluid retention and cardiovascular health.

  • Reduces Fluid Retention: Helps remove excess fluid from the body, relieving swelling in the legs, ankles, abdomen, and other affected areas.
  • Improves Breathing Comfort: By reducing fluid buildup, it may help relieve breathlessness associated with certain heart and liver conditions.
  • Lowers Blood Pressure: Helps control high blood pressure and reduces strain on the heart and blood vessels.
  • Protects Heart and Blood Vessel Health: Effective blood pressure control may help reduce the long-term risk of heart attack, stroke, and other cardiovascular complications.
  • Helps Maintain Potassium Levels: Unlike many other diuretics, Spironol-50 Tablet 10's helps conserve potassium, reducing the risk of low potassium-related muscle cramps and weakness.

Directions for Use

  • Spironol-50 Tablet 10's can be taken with or without food. However, taking it with food may help reduce side effects like nausea (feeling sick).
  • It is usually taken once daily in the morning; however, your doctor may adjust the dose of this medication based on your medical condition.
  • Swallow the medication as a whole with water.
  • Do not crush, break, or chew it.

How Spironol-50 Tablet 10's Works

The active ingredient, spironolactone, is a potassium-sparing diuretic (water tablet). It works by blocking the action of a natural hormone in your body called aldosterone. Aldosterone normally signals your kidneys to hold onto sodium and water while excreting potassium. By blocking this hormone, Spironol-50 Tablet 10's prompts your kidneys to pass more sodium and water into your urine, while holding onto potassium. This process decreases the overall volume of fluid circulating through your blood vessels, lowering your blood pressure and easing swelling without depleting your potassium levels.
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Alcohol

Caution

You are recommended not to consume alcohol along with Spironol-50 Tablet 10's to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

Spironol-50 Tablet 10's is not recommended during pregnancy unless strongly advised by your doctor. Please consult your doctor so that the dosage of Spironol-50 Tablet 10's can be prescribed accordingly.

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Breast Feeding

Unsafe

Breastfeeding should be avoided during treatment with Spironol-50 Tablet 10's.

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Driving

Unsafe

It is not recommended to drive after taking Spironol-50 Tablet 10's, as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).

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Liver

Caution

Spironol-50 Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver condition.

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Kidney

Caution

Spironol-50 Tablet 10's to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney condition.

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Children

Unsafe

Spironol-50 Tablet 10's is not recommended for children below 12 years of age, as its safety and effectiveness have not been established.

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Heart

Safe if prescribed

Spironol-50 Tablet 10's is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Spironol-50 Tablet 10's should be used with caution in geriatric patients as it can cause side effects, including increased potassium levels in some cases. Please consult your physician.

What if I have taken an overdose of Spironol-50 Tablet 10's

If you suspect an overdose, seek immediate medical attention or contact a poison control centre right away. Symptoms of an overdose can include severe drowsiness, confusion, muscle

Diet & Lifestyle Advise

  • Avoid Potassium-Containing Salt Substitutes: Do not use salt substitutes containing potassium unless advised by your doctor.
  • Monitor Potassium Intake: Limit excessive consumption of potassium-rich foods, such as bananas, oranges, leafy green vegetables, and coconut water, if recommended by your healthcare provider.
  • Maintain Appropriate Hydration: Stay hydrated, but follow your doctor's advice regarding fluid intake, especially if you have heart failure or fluid retention.
  • Track Blood Pressure and Weight: Monitor your blood pressure and body weight regularly and share these records with your healthcare provider.
  • Avoid Alcohol: Limit or avoid alcohol, as it may increase dizziness, lightheadedness, and the risk of fainting.

Have a query?

How Soon It Starts Working

  • The time required for Spironol-50 Tablet 10's to start to work: Spironol-50 Tablet 10's ideally shows its action within 2 to 4 hours after administration.
  • The time for which the effects of Spironol-50 Tablet 10's last: The effect of Spironol-50 Tablet 10's lasts for 2 to 3 days.

What if you forget to take Spironol-50 Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Spironol-50 Tablet 10's tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original packaging to protect them from light and moisture.

Drug Warnings

  • Stand Up Slowly: Rise gradually from sitting or lying positions to help prevent dizziness and reduce the risk of falls.
  • Attend Regular Blood Tests: Keep all appointments for kidney function and potassium monitoring, as regular testing is important during treatment.
  • Inform Healthcare Providers: Tell your doctor, dentist, surgeon, or other healthcare professionals that you are taking Spironol-50 Tablet 10's before any medical procedure.
  • Check Before Use: Do not take tablets that appear damaged, chipped, or discoloured.
  • Use Caution During Activities: Avoid driving or operating machinery until you know how Spironol-50 Tablet 10's affects you, as it may cause dizziness or drowsiness.

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Spironol-50 Tablet 10's:

  • ACE Inhibitors, ARBs, and Potassium Supplements: These medicines may increase the risk of dangerously high potassium levels when used with Spironol-50 Tablet 10's.
  • NSAIDs: Medicines such as ibuprofen may reduce the effectiveness of Spironol-50 Tablet 10's and increase the risk of kidney problems.
  • Lithium: Spironol-50 Tablet 10's may increase lithium levels in the body, raising the risk of lithium toxicity.


Drug-Food Interactions

Certain foods and beverages may affect how Spironol-50 Tablet 10's works or increase the risk of side effects: 

  • Potassium-Containing Salt Substitutes: Avoid salt substitutes containing potassium, as they may increase the risk of high blood potassium levels.
  • High-Potassium Foods: Excessive intake of potassium-rich foods may increase the risk of hyperkalaemia and should be discussed with your doctor.


Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Spironol-50 Tablet 10's, as it may worsen your condition or require closer monitoring.

  • Kidney Disease: Severe kidney impairment is a contraindication, while mild to moderate kidney disease requires close monitoring of kidney function and potassium levels.
  • Addison's Disease: Spironol-50 Tablet 10's is not recommended for people with Addison's disease.
  • Hyperkalaemia: Do not use this medicine if you already have high potassium levels in your blood.
  • Liver Disease: Inform your doctor if you have liver impairment, as closer monitoring may be needed during treatment.

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Habit Forming

No

Therapeutic Class

[DIURETIC]

FAQs

Spironol-50 Tablet 10's is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure.

Spironol-50 Tablet 10's contains spironolactone (a short-acting diuretic) that increases the amount of urine excreted by the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Yes, Spironol-50 Tablet 10's may affect the menstrual cycle. It can lead to irregular and painful periods. In addition to this, taking Spironol-50 Tablet 10's can also lead to pain and swelling of the breast. If any of these problems persist and discomfort increases, please consult your doctor for the best advice.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

Store in a cool, dry place, away from heat and direct light. Keep Spironol-50 Tablet 10's out of the sight and reach of children.

Avoid using potassium-rich supplements. Combining potassium-rich foods with spironolactone can result in elevated potassium levels. Excess potassium can cause irregular heartbeat, perhaps leading to a heart attack and other complications.

Spironol-50 Tablet 10's is not recommended during pregnancy or breastfeeding unless strongly advised by your doctor. If you have any concerns regarding this, please consult your doctor.

As Spironol-50 Tablet 10's is a potassium-sparing diuretic, you should avoid alcoholic beverages and potassium-containing supplements or sports drinks, as well as consuming too many high-potassium foods such as papaya, cantaloupe, prune juice, honeydew melons, bananas, raisins, mangoes, kiwis, oranges, orange juice, tomatoes, tomato juice, white and sweet potatoes, asparagus, pumpkin, and Brussels sprouts. Avoid salt replacements containing potassium chloride rather than sodium chloride and low-sodium milk products.

Spironol-50 Tablet 10's is usually taken once a day in the morning, but some people should take it twice. If you take it twice daily, take the second dose 4 hours before going to bed. Waiting until later may mean you have to wake up at night to pee. Even so, following the doctor's directions is essential for obtaining the maximum benefits of Spironol-50 Tablet 10's.

If you forget to take a dose of Spironol-50 Tablet 10's, take it as soon as you remember, unless it's after 6 p.m. In this case, skip the missed dose and take your next dose at the usual time the next day. Do not take two doses to make up for a forgotten dose.

Yes, Spironol-50 Tablet 10's can be used to treat hypertension. It works by increasing the amount of urine passed out from the kidneys. This effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of future heart attack, stroke, or angina (chest pain).

No, Spironol-50 Tablet 10's is not intended for weight loss. However, it might help reduce weight related to fluid retention, especially in women with bloating and swelling due to PMS. Even so, do not use this medication on your own without consulting your doctor.

Here are some lifestyle changes you should consider while taking Spironol-50 Tablet 10's such as: • Stay hydrated by drinking plenty of water. • Engage in moderate exercise like walking or swimming. • Get enough sleep. • Manage stress through relaxation techniques like yoga or meditation. • Limit your intake of potassium-rich foods like bananas, spinach, and potatoes. • Avoid salt substitutes containing potassium. • Avoid alcohol and caffeine, as they can increase dehydration.

Spironol-50 Tablet 10's does not affect any type of contraception, including the combined pill and emergency contraception.

No, usually, it does not impact the kidney. Spironol-50 Tablet 10's may reduce proteinuria and retard renal progression in chronic kidney disease patients.

Swallow the tablet whole with a drink of water. Do not chew it. Take Spironol-50 Tablet 10's with a meal to help reduce side effects such as feeling sick. Follow the doctor's recommendations for dose and duration.

Common side effects of Spironol-50 Tablet 10's may include hypotension (low blood pressure), dehydration, drowsiness, dizziness, hyperkalaemia (high potassium levels), hyponatraemia (low sodium levels), elevated creatinine levels, headache, vomiting, nausea, diarrhoea, fatigue, weakness, lethargy (somnolence), gynaecomastia (breast enlargement in males), and amenorrhea (absence of periods in females). Most of the side effects of Spironol-50 Tablet 10's do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, contact your doctor.

Yes, Spironol-50 Tablet 10's may interact with certain medications such as blood pressure-lowering pills, anti-epilepsy medicines, immune-suppressing drugs, anti-depression medicines and so on. So, do not take any other medication with Spironol-50 Tablet 10's unless recommended by the doctor.

Before taking the Spironol-50 Tablet 10's, let your doctor know about all your medical conditions, sensitivities, and medications you are using. And inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

If prescribed, you can take Spironol-50 Tablet 10's for a long time. Your doctor may perform specific blood tests during the treatment to ensure that the electrolytes in your blood, such as potassium, are correctly balanced.

Spironol-50 Tablet 10's can make some people feel dizzy or tired, especially when they first start taking it or after taking a more significant dose. If this happens, do not drive a car or ride a bike until you feel better.

You are recommended not to consume alcohol along with Spironol-50 Tablet 10's to avoid unpleasant side effects.

Yes, because Spironol-50 Tablet 10's is a water tablet (diuretic), it helps your body get rid of excess water by increasing how often you urinate, especially when you first start taking it. Talk to your doctor or pharmacist if this becomes highly bothersome.

For fluid retention, you may notice a difference in a few days, but for high blood pressure, it may take several weeks to see the full benefit. Talk to your doctor or pharmacist if you feel your condition is not improving.

Your doctor will order regular blood tests to check your kidney function and monitor your potassium levels to make sure they do not rise too high. Talk to your doctor or pharmacist if you miss a scheduled blood test.

Yes, Spironol-50 Tablet 10's can cause breast tenderness or enlargement in both men and women due to its effects on certain hormones. This is usually reversible once the medicine is stopped. Talk to your doctor or pharmacist if this becomes uncomfortable or concerning.

Spironol-50 Tablet 10's can help reduce the effects of certain hormones called androgens, which may contribute to acne, oily skin, and excessive hair growth in some women. It is commonly prescribed by dermatologists and gynaecologists for these conditions. Talk to your doctor if you have questions about why this medicine has been recommended for you.

The duration of treatment depends on the condition being treated. Some people take Spironol-50 Tablet 10's for a few weeks to manage fluid retention, while others may use it long term for heart failure, high blood pressure, acne, or hormonal conditions. Your doctor will review your progress regularly and determine how long treatment should continue.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

M-17, Pharma Tower, Basement & Ground Floor, Badli Industrial Area, New Delhi 110 042.
Other Info - SPI0488
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