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compositionComposition:AMISULPRIDE-50MG
prescriptionPrescription Medicine

$anem is used to treat mental health conditions such as schizophrenia. It helps improve abnormal thoughts, hallucinations, mood changes, and behavioural problems by balancing certain chemical messengers in the brain, thereby improving mental stability and daily functioning.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMISULPRIDE-50MG

Manufacturer/Marketer :

Cyrus Remedies Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Synapride-50 Tab

Synapride-50 Tab is primarily used to treat long-term (chronic) schizophrenia. In schizophrenic disorders, there are positive symptoms (like delusions, hallucinations and thought disorders) along with negative symptoms (like blunted affect, emotional and social withdrawal).

Synapride-50 Tab contains amisulpride, which helps balance dopamine activity in the brain. It improves thinking, mood, and behaviour while reducing abnormal mental symptoms. It also supports better emotional and social functioning. This helps maintain mental stability and daily well-being.

Take Synapride-50 Tab as prescribed by your doctor. Common side effects include drowsiness, dizziness, weight gain, increased appetite, nausea, vomiting, constipation, dry mouth, blurred vision, insomnia (trouble sleeping), anxiety, or agitation (feeling restless or uneasy). If you notice any side effects that are not manageable, please consult your doctor.

Synapride-50 Tab should be avoided if you are allergic to it or any other medicines. Synapride-50 Tab is not recommended for children under 18 years. Synapride-50 Tab should not be taken if you are pregnant or breastfeeding. Use Synapride-50 Tab with extreme caution in elderly patients above 65 years of age, as there is an increased risk of severe adverse effects.  

Uses of Synapride-50 Tab

Synapride-50 Tab is used in the treatment of schizophrenia. The detailed uses of Synapride-50 Tab are as follows:

  • Schizophrenia: Synapride-50 Tab is used in the treatment of both acute and chronic schizophrenia, helping to manage symptoms like hallucinations, delusions, and disorganised thinking, and improving quality of life and social functioning.

Key Benefits

  • Helps reduce hallucinations, delusions, and disturbed thinking.
  • Improves clarity of thoughts and emotional control.
  • Supports better daily functioning and social interaction.
  • Helps manage both acute and long-term symptoms.
  • Improves overall quality of life and mental stability.
Side effects of Synapride-50 Tablet
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.

Directions for Use

  • Synapride-50 Tab can be taken before meals or as advised by your doctor.
  • Take Synapride-50 Tab twice daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow the medicines as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Synapride-50 Tab Works

Amisulpride acts by regulating dopamine activity in the brain. It reduces excessive dopamine signals related to hallucinations (seeing or hearing things that are not real) and disordered thinking while preserving normal brain function. This helps stabilise mood, behaviour, and overall mental health.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Synapride-50 Tab as it may lead to increased dizziness and drowsiness.

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Pregnancy

Caution

Synapride-50 Tab should not be taken by pregnant women. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Synapride-50 Tab is unsafe and should not be taken by breastfeeding mothers. Consult your doctor for further advice.

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Driving

Caution

Synapride-50 Tab may cause dizziness, drowsiness and uncontrolled movements. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Take Synapride-50 Tab with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. However, Synapride-50 Tab is not recommended for patients with severe liver disease. Inform your doctor immediately if you experience fatigue, loss of appetite, nausea, vomiting, abdominal pain or yellow discolouration of the eyes or skin.

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Kidney

Caution

Synapride-50 Tab should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustments and regular monitoring of electrolytes may be required as it may alter electrolyte levels in the body.

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Children

Unsafe

Synapride-50 Tab should not be given to children, as its safety and effectiveness have not been established.

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Heart

Caution

Synapride-50 Tab may be used in patients with heart disease if prescribed by a physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Synapride-50 Tab should be used with caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Synapride-50 Tab

Take Synapride-50 Tab only as prescribed by the physician. Avoid exceeding the recommended dose, as this may lead to adverse effects. Symptoms of adverse effects may include tremors, bradycardia, seizures, involuntary muscle movements, and syncope. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Mood Monitoring:

  • Track your mood regularly alongside sleep, medications, and daily activities.
  • Noting patterns can help manage mood changes better.

Physical Activity:

  • Exercise daily to relieve tension and improve mental well-being.
  • Regular physical activity also helps prevent weight gain related to medications.

Stress Management:

  • Practice calming techniques like meditation and deep breathing.
  • These methods help reduce stress and emotional strain.

Sleep Routine:

  • Get enough sleep each night to help stabilise mood.
  • Maintain a regular sleep schedule.

Diet:

  • Eat a healthy, balanced diet to support mental health.
  • Keep a food log to see how certain foods affect your mood.
  • Discuss diet choices with your doctor or nutritionist if needed.

Positive Mindset:

  • Stay optimistic and patient with treatment progress.
  • Improvement takes time, and consistent care supports recovery.

Have a query?

How Soon It Starts Working

  • The time required for Synapride-50 Tab to start to work: Synapride-50 Tab ideally starts to show its action within 1 to 2 hours of administration.
  • The time for which the effects of Synapride-50 Tab last: Synapride-50 Tab effect lasts for 24 hours.

What if you forget to take Synapride-50 Tab

If you miss a dose of Synapride-50 Tab , take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Synapride-50 Tab out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Synapride-50 Tab if you are allergic (hypersensitive) to amisulpride or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumour or breast cancer, phaeochromocytoma (a tumour on the adrenal gland), or pituitary tumour.
  • Synapride-50 Tab should not be given to children as safety has not been established.
  • Use Synapride-50 Tab with extreme caution in elderly patients above 65 years of age, as there is an increased risk of severe adverse effects.
  • Synapride-50 Tab should not be taken if you are pregnant or breastfeeding. Synapride-50 Tab may impair fertility, so inform your doctor if you are planning a pregnancy.
  • Inform your doctor if you are previously diagnosed with kidney disease, liver disease epilepsy or seizures (fits), Parkinson's disease, unusual heart rate (rhythm), slow heartbeat (less than 55 beats per minute), low potassium levels in your blood, prolonged QT interval (heart conduction problem), if you or someone else in your family has a history of blood clots, heart problems, stroke, diabetes, have a low number of white blood cells (agranulocytosis), leucopenia (blood disorder).
  • Synapride-50 Tab may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Synapride-50 Tab as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

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Drug-Drug Interaction: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.

  • Heart rhythm medicine – Antiarrhythmic (Dronedarone)
    • Potential effect: May increase the risk of severe irregular heart rhythm and serious cardiac side effects.
  • Stomach-movement medicines (Cisapride, Metoclopramide)
    Potential effect: May increase the risk of irregular heart rhythm, especially in patients with heart problems.
  • Antipsychotic medicines (Pimozide, Ziprasidone)
    Potential effect: May increase the risk of severe irregular heart rhythm and lead to serious side effects.
  • Anti-HIV medicine (Saquinavir)
    Potential effect: May increase the risk of severe irregular heart rhythm.
  • Antibiotic medicine (Grepafloxacin)
    Potential effect: May increase the risk of severe irregular heart rhythm.
  • Heart-related medicine used for chest pain (Ranolazine)
    Potential effect: May increase the risk of severe irregular heart rhythm when used together.

Drug- Food Interaction:

  • Grapefruit juice and Alcohol: Avoid grapefruit juice and alcohol while taking Synapride-50 Tab , as they may increase the risk of side effects.

Drug-Disease Interaction: Inform your doctor if you have a history of this condition before taking Synapride-50 Tab .

  • Breast cancer
  • Pheochromocytoma (tumour of the adrenal gland)
  • Pituitary gland prolactinoma (tumour of the pituitary gland)
  • Fits
  • Parkinson’s disease
  • Kidney problems
  • Heart problems
AmisulprideGrepafloxacin
Critical

Drug-Drug Interactions

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How does the drug interact with Synapride-50 Tablet:
Taking Pimozide with Synapride-50 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Pimozide with Synapride-50 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideGrepafloxacin
Critical
How does the drug interact with Synapride-50 Tablet:
Taking Synapride-50 Tablet with Grepafloxacin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Synapride-50 Tablet with Grepafloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Synapride-50 Tablet:
Co-administration of Ziprasidone with Synapride-50 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Synapride-50 Tablet but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Synapride-50 Tablet:
Taking Synapride-50 Tablet with Dronedarone can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Synapride-50 Tablet with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Synapride-50 Tablet:
Taking Synapride-50 Tablet with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Synapride-50 Tablet with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideSaquinavir
Critical
How does the drug interact with Synapride-50 Tablet:
Taking Saquinavir with Synapride-50 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Synapride-50 Tablet with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Synapride-50 Tablet:
Taking Metoclopramide with Synapride-50 Tablet may increase the risk or severity of side effects.

How to manage the interaction:
Taking Synapride-50 Tablet with Metoclopramide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideMesoridazine
Critical
How does the drug interact with Synapride-50 Tablet:
Taking Synapride-50 Tablet with Mesoridazine can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Synapride-50 Tablet with Mesoridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideDroperidol
Severe
How does the drug interact with Synapride-50 Tablet:
Using Synapride-50 Tablet together with droperidol can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Synapride-50 Tablet and Droperidol together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any of these symptoms - irregular heartbeat, heart problems, a condition called long qt syndrome, issues with your heart's electrical system, severe or long-lasting diarrhea, vomiting, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations - call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Synapride-50 Tablet:
Taking Synapride-50 Tablet with granisetron increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking granisetron along with Synapride-50 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Synapride-50 Tab is used to treat long-term (chronic) schizophrenia.

Synapride-50 Tab contains amisulpride, which works by balancing dopamine activity in the brain. It improves thinking, mood, and behaviour while reducing abnormal mental symptoms.

Synapride-50 Tab can be used to treat psychotic disorders like schizophrenia, bipolar disorder and depression. However, you should not take this medication without a doctor's advice.

Synapride-50 Tab may affect fertility as it may cause hyperprolactinemia (excessive levels of prolactin hormone in the blood) resulting in amenorrhea (absence of menstrual periods), anovulation (lack of egg release) and impaired fertility.

You are not recommended to stop taking Synapride-50 Tab without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Synapride-50 Tab for as long as your doctor has prescribed it, and if you experience any difficulty while taking Synapride-50 Tab , please consult your doctor so that the dose may be gradually reduced.

Synapride-50 Tab is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Synapride-50 Tab .

Stopping Synapride-50 Tab abruptly can cause withdrawal symptoms, and stopping it too early could make your illness come back. Please consult your doctor if you want to stop taking Synapride-50 Tab .

Take Synapride-50 Tab with caution in patients with diabetes, as it may increase the risk of having diabetes. It is advised to monitor your blood sugar levels regularly while taking Synapride-50 Tab .

Synapride-50 Tab is not recommended for children as the safety and effectiveness have not been established.

Synapride-50 Tab should be used with caution and only if prescribed by the doctor in elderly patients due to the possible risk of low blood pressure and sedation.

Synapride-50 Tab should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustment and regular electrolyte monitoring may be required, as Synapride-50 Tab may alter electrolyte levels.

Synapride-50 Tab may cause sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

Synapride-50 Tab should be taken at the same time daily or as prescribed by the doctor.

Synapride-50 Tab modulates certain chemical messengers (dopamine D2) in the brain, which helps regulate mood and behaviour.

No, Synapride-50 Tab is not indicated for anxiety. It is used to treat schizophrenia and postoperative nausea and vomiting.

Do not take Synapride-50 Tab if you are allergic (hypersensitive) to amisulpride or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumour or breast cancer, phaeochromocytoma (a tumour on the adrenal gland), or pituitary tumour.

No, Synapride-50 Tab has no habit-forming tendency and is not addictive.

Withdrawal symptoms of Synapride-50 Tab are nausea, vomiting, difficulty sleeping, sweating, extreme restlessness, abnormal movements, or muscle stiffness.

Synapride-50 Tab may cause side effects such as dry mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to remain still), parkinsonism, and increased blood prolactin levels. Most of these side effects of Synapride-50 Tab do not require medical attention and gradually resolve over time. However, if the side effects persist, consult your doctor immediately.

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Country of origin

India
Other Info - SYN0357
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