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  3. Tacromus 2 mg Capsule 10's

Tacromus 2 mg Capsule 10's, Pack of 10 CAPSULES
Tacromus 2 mg Capsule 10's, Pack of 10 CAPSULES
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tacromus 2 mg Capsule is used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. It contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that normally attack foreign invaders and defend the body against foreign cells and infection. Thus, it prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

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Composition :

TACROLIMUS-2MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tacromus 2 mg Capsule

Tacromus 2 mg Capsule is used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Tacromus 2 mg Capsule contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that normally attack foreign invaders and defend the body against foreign cells and infection. Thus, it prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

Take Tacromus 2 mg Capsule as prescribed. You are advised to use Tacromus 2 mg Capsule for as long as your doctor has recommended it for you based on your medical condition. Some people may experience nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. Most of these side effects of Tacromus 2 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tacrolimus or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacromus 2 mg Capsule . Avoid alcohol consumption with Tacromus 2 mg Capsule . Drive only if you are alert, as Tacromus 2 mg Capsule may cause some people vision problems or nervous disturbances. If you are about to get vaccinated, inform your doctor before taking Tacromus 2 mg Capsule . Tacromus 2 mg Capsule may increase the risk of infections or skin cancer as it lowers the body’s immune defence system.

Uses of Tacromus 2 mg Capsule

Tacromus 2 mg Capsule is used for prevention of transplanted organ rejection

Directions for Use

Take the capsule as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tacromus 2 mg Capsule contains Tacrolimus, an immunosuppressant used to prevent organ rejection after a transplant. Tacromus 2 mg Capsule suppresses the activity of T and B lymphocytes (cells in the immune system) that normally attack foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tacromus 2 mg Capsule
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Tacromus 2 mg Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. This medicine may be harmful if swallowed. Seek emergency medical attention or call your doctor if you notice any unusual symptoms or if anyone has accidentally swallowed the medication.

Drug Warnings

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacromus 2 mg Capsule . Avoid alcohol consumption with Tacromus 2 mg Capsule . Drive only if you are alert, as Tacromus 2 mg Capsule may cause vision problems or nervous disturbances in some people. If you are about to get vaccinated, inform your doctor before taking Tacromus 2 mg Capsule . Tacromus 2 mg Capsule may increase the risk of infections or skin cancer as it lowers the body’s immune defence system. While taking Tacromus 2 mg Capsule , you are advised to wear protective clothing and sunscreen while going out. You are recommended to use glass or metal materials to prepare the oral suspension. Avoid using plastic (PVC) materials to prepare the suspension, as the granules will stick to a plastic container, and your child may not receive their full dose. Do not inhale or let the granules or prepared oral suspension come in contact with your skin or eyes. In case of accidental contact with skin, wash the area well with soap and water, and if it comes in contact with the eyes, rinse with plain water.

Drug-Drug Interactions

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TacrolimusDronedarone
Critical
TacrolimusCidofovir
Critical

Drug-Drug Interactions

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TacrolimusDronedarone
Critical
How does the drug interact with Tacromus 2 mg Capsule:
Taking Tacromus 2 mg Capsule with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacromus 2 mg Capsule with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusCidofovir
Critical
How does the drug interact with Tacromus 2 mg Capsule:
Taking cidofovir with Tacromus 2 mg Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Tacromus 2 mg Capsule with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
TacrolimusZiprasidone
Critical
How does the drug interact with Tacromus 2 mg Capsule:
Taking Tacromus 2 mg Capsule with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacromus 2 mg Capsule with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TacrolimusMifepristone
Critical
How does the drug interact with Tacromus 2 mg Capsule:
Taking Tacromus 2 mg Capsule with Mifepristone may significantly increase the blood levels of Tacromus 2 mg Capsule, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacromus 2 mg Capsule with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
TacrolimusThioridazine
Critical
How does the drug interact with Tacromus 2 mg Capsule:
Combining Tacromus 2 mg Capsule with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacromus 2 mg Capsule with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusSaquinavir
Critical
How does the drug interact with Tacromus 2 mg Capsule:
Taking Tacromus 2 mg Capsule with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacromus 2 mg Capsule with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusAdalimumab
Severe
How does the drug interact with Tacromus 2 mg Capsule:
Taking Tacromus 2 mg Capsule with Adalimumab may increase the risk of serious infections.

How to manage the interaction:
Although taking Tacromus 2 mg Capsule and adalimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TacrolimusBoceprevir
Severe
How does the drug interact with Tacromus 2 mg Capsule:
Taking Tacromus 2 mg Capsule with boceprevir may significantly increase the blood levels of Tacromus 2 mg Capsule, which may lead to kidney problems, high blood pressure, heart problems and hyperkalemia(high potassium levels in blood).

How to manage the interaction:
Although taking Tacromus 2 mg Capsule and boceprevir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
TacrolimusEfavirenz
Severe
How does the drug interact with Tacromus 2 mg Capsule:
Taking Tacromus 2 mg Capsule together with efavirenz can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Tacromus 2 mg Capsule and efavirenz together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
TacrolimusAmiloride
Severe
How does the drug interact with Tacromus 2 mg Capsule:
Taking amiloride with Tacromus 2 mg Capsule may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Tacromus 2 mg Capsule and amiloride together may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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TACROLIMUS-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TACROLIMUS-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Tacromus 2 mg Capsule treatment may lead to increased Tacromus 2 mg Capsule levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Tacromus 2 mg Capsule.

Diet & Lifestyle Advise

  • Include fruits and vegetables in your daily routine.
  • Follow a vitamin-C-rich diet.
  • Reduce salt intake.
  • Eat a handful of walnuts and almonds every day.
  • Reduce intake of unhealthy cholesterol and fats.
  • Consume dark chocolate with at least 70% cocoa.

Liver and Heart transplant:

  • Eat whole-grain bread, cereals and other grains, fruits and vegetables, lean meats, fish and poultry.
  • Maintain a low-fat and low-salt diet.
  • Drink low-fat milk or eat other low-fat dairy products to maintain adequate calcium.
  • Stay hydrated by drinking sufficient water and other fluids.
  • Avoid alcohol consumption.
  • Avoid grapefruit and grapefruit juice. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Tacromus 2 mg Capsule Substitute

Substitutes safety advice

  • Pangraf 2 Capsule 10's

    by Others

    ₹78.58per tablet

  • Tacrograf 2 Capsule 10's

    by Others

    ₹84.96per tablet

  • Biomus 2 mg Capsule 10's

    by Others

    ₹78.30per tablet

  • Takfa-2 Capsule 10's

    by Others

    ₹85.01per tablet

  • Tacstead 2 mg Capsule 10's

    by AYUR

    ₹78.30per tablet

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption with Tacromus 2 mg Capsule as it may increase the risk of adverse effects. Please consult a doctor before consuming alcohol with Tacromus 2 mg Capsule .

bannner image

Pregnancy

Caution

Using Tacrolimus during pregnancy may cause kidney dysfunction or neonatal hyperkalemia (high potassium levels in the blood). Therefore, please consult a doctor if you are pregnant before taking Tacromus 2 mg Capsule and if you are a woman of childbearing age, use effective contraceptive methods while using Tacromus 2 mg Capsule .

bannner image

Breast Feeding

Consult your doctor

Tacromus 2 mg Capsule may be excreted in breast milk. Therefore, please inform your doctor if you are a breastfeeding mother before taking Tacromus 2 mg Capsule . You should avoid taking Tacromus 2 mg Capsule during breastfeeding or avoid breastfeeding while on treatment with Tacromus 2 mg Capsule .

bannner image

Driving

Caution

Tacromus 2 mg Capsule may cause vision problems or nervous disturbances in a few people. Therefore, avoid driving if you experience any of these symptoms after taking Tacromus 2 mg Capsule .

bannner image

Liver

Consult your doctor

Please consult a doctor if you have liver diseases/conditions before taking Tacromus 2 mg Capsule .

bannner image

Kidney

Consult your doctor

Please consult a doctor if you have Kidney diseases/conditions before taking Tacromus 2 mg Capsule .

bannner image

Children

Safe if prescribed

Tacromus 2 mg Capsule should be used in children in doses as advised by a doctor only.

Have a query?

FAQs

Tacromus 2 mg Capsule is used to prevent rejection of a transplanted organ such as a liver, kidney, or heart.

Tacromus 2 mg Capsule contains Tacrolimus, an immunosuppressant that works by the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Tacromus 2 mg Capsule may increase the risk of infections as it may weaken the immune system. Therefore, consult a doctor immediately if you have any signs of infection, such as sore throat or fever.

Tacromus 2 mg Capsule may increase the risk of skin cancer. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella (MMR), oral polio, varicella, yellow fever, intranasal influenza, BCG and TY21a typhoid vaccines, inform your doctor that you are taking Tacromus 2 mg Capsule because it may reduce the effectiveness of the vaccine and increase your risk of contracting the infection that the vaccine is meant to protect against.

Using Tacromus 2 mg Capsule with Sirolimus is not recommended in patients who have had heart or liver transplants. It is unknown if kidney transplant recipients can use it safely. Hence, please seek medical advice before combining Tacromus 2 mg Capsule with other medications.

Tacromus 2 mg Capsule may cause tremors, trembling and shaking of hands. Consult the doctor if this becomes bothersome.

Tacromus 2 mg Capsule is usually taken on an empty stomach or 2 to 3 hours after a meal. Wait at least 1 hour until the next meal.

Tacromus 2 mg Capsule is a macrolide antibiotic with immunosuppressant properties.

Tacromus 2 mg Capsule should not be taken by people who are allergic to any of its components, allergic to sirolimus or any macrolide-antibiotic, during breastfeeding, and receiving live vaccines.

Let the doctor know if you have long QT syndrome, low or high levels of potassium, low levels of calcium or magnesium, an irregular heartbeat, high blood pressure, high cholesterol levels, cystic fibrosis (an inborn disease), heart, kidney, or liver disease. Inform the doctor if you have a weak immune system or if you are due to undergo any vaccination.

Tacromus 2 mg Capsule decreases the activity of your immune system, increasing the risk of serious infection and cancer (lymphoma cancer). Consult the doctor if you experience symptoms of infection (sore throat, extreme tiredness, cough, flu-like symptoms, fever,) or cancer (weight loss, swollen lymph nodes in the neck, armpits, or groin, fever, excessive tiredness or weakness, night sweats, cough, chest pain, trouble breathing, or pain, swelling, or fullness in the stomach area).

No, Tacromus 2 mg Capsule does not have an abuse potential as it is not a controlled substance.

Side effects of Tacromus 2 mg Capsule include nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad €“ 380015 Gujarat, India.
Other Info - TAC0177

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 29, 2025 | 10:54 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf
  2. https://www.medsafe.govt.nz/consumers/cmi/t/tacrolimussandozcap.pdf
  3. https://www.astellas.com/us/system/files/prografwpi_3.pdf
  4. https://www.medicines.org.uk/emc/product/461/smpc
  5. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210115s000,050708s047,050709s040lbl.pdf
  6. https://www.drugs.com/cdi/tacrolimus-granules-for-suspension.html
  7. https://www.astellas.com/us/system/files/prografinstructionstouse_2.pdf
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